Germ cell tumor
Information
- Disease name
- Germ cell tumor
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03426865 | Active, not recruiting | Role of Axumin PET Scan in Germ Cell Tumor | March 1, 2018 | July 5, 2024 | |
| NCT03500991 | Active, not recruiting | Phase 1 | HER2-specific CAR T Cell Locoregional Immunotherapy for HER2-positive Recurrent/Refractory Pediatric CNS Tumors | July 26, 2018 | July 26, 2039 |
| NCT02076906 | Active, not recruiting | Phase 1 | MR-guided High Intensity Focused Ultrasound (HIFU) on Pediatric Solid Tumors | April 2014 | November 24, 2024 |
| NCT04483778 | Active, not recruiting | Phase 1 | B7H3 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | July 13, 2020 | December 2040 |
| NCT04035447 | Active, not recruiting | N/A | Symptom Management for YA Cancer Survivors | January 22, 2020 | May 30, 2024 |
| NCT02375204 | Active, not recruiting | Phase 3 | Standard-Dose Combination Chemotherapy or High-Dose Combination Chemotherapy and Stem Cell Transplant in Treating Patients With Relapsed or Refractory Germ Cell Tumors | August 5, 2015 | June 2024 |
| NCT03158064 | Active, not recruiting | Phase 2 | Evaluating Immune Therapy, Duravalumab (MEDI4736) With Tremelimumab for Relapsed/Refractory Germ Cell Tumors | May 15, 2017 | November 2024 |
| NCT03418844 | Active, not recruiting | N/A | Living After a Rare Cancer of the Ovary: Chronic Fatigue, Quality of Life and Late Effects of Chemotherapy | May 7, 2018 | December 2024 |
| NCT03638167 | Active, not recruiting | Phase 1 | EGFR806-specific CAR T Cell Locoregional Immunotherapy for EGFR-positive Recurrent or Refractory Pediatric CNS Tumors | March 19, 2019 | March 2040 |
| NCT03950830 | Completed | Phase 2 | Disulfiram and Cisplatin in Refractory TGCTs. | May 14, 2019 | January 31, 2022 |
| NCT03194906 | Completed | Phase 2 | Memantine for Prevention of Cognitive Late Effects in Pediatric Patients Receiving Cranial Radiation Therapy for Localized Brain Tumors | November 7, 2017 | June 28, 2023 |
| NCT01331135 | Completed | Phase 1 | Aflac ST0901 CHOANOME - Sirolimus in Solid Tumors | April 2011 | August 9, 2017 |
| NCT01466231 | Completed | Phase 2 | Everolimus in Refractory Testicular Germ Cell Cancer | November 2011 | June 2015 |
| NCT01625351 | Completed | Phase 1 | A Study of CD45RA+ Depleted Haploidentical Stem Cell Transplantation in Children With Relapsed or Refractory Solid Tumors and Lymphomas | August 20, 2012 | February 10, 2020 |
| NCT06341998 | Completed | Phase 2/Phase 3 | Clinical Study of Chemotherapy in the Treatment of Recurrent/Refractory Yolk Sac Tumor in Children | June 1, 2020 | February 1, 2024 |
| NCT02340884 | Completed | Phase 2 | A Pilot RCT of the PRISM Intervention for AYAs With Cancer | January 30, 2015 | December 19, 2021 |
| NCT02414685 | Completed | Phase 2 | First Line TIP in Poor Prognosis TGCTs. | April 2015 | June 2020 |
| NCT02429466 | Completed | Phase 1 | Study of the Hypomethylating Drug Guadecitabine (SGI-110) Plus Cisplatin in Relapsed Refractory Germ Cell Tumors | April 27, 2015 | February 13, 2019 |
| NCT06329323 | Not yet recruiting | SerUm and Plasma MicroRNAs in Malignant Ovarian gERm Cell Tumours | April 14, 2024 | April 2028 | |
| NCT06363201 | Not yet recruiting | N/A | Effect and Safety of Ocoxin Oral Solution on the Quality of Life of Paediatric Patients With Advanced Stage Solid Tumours | April 28, 2024 | December 15, 2025 |
| NCT06421805 | Recruiting | Establishing Prospective Mediastinal Tumor Database of PUMCH | January 1, 2012 | December 30, 2045 | |
| NCT00898755 | Recruiting | Collecting and Storing Tissue From Young Patients With Cancer | March 5, 2007 | ||
| NCT02099734 | Recruiting | Germ Cell Tumor and Testicular Tumor DNA Registry | January 2014 | January 2026 | |
| NCT03067181 | Recruiting | Phase 3 | Active Surveillance, Bleomycin, Etoposide, Carboplatin or Cisplatin in Treating Pediatric and Adult Patients With Germ Cell Tumors | May 25, 2017 | June 30, 2027 |
| NCT04435756 | Recruiting | A Study of miRNA 371 in Patients With Germ Cell Tumors | July 28, 2020 | October 1, 2026 | |
| NCT04791228 | Recruiting | Phase 2 | A Pilot Study of Thermodox and MR-HIFU for Treatment of Relapsed Solid Tumors | November 10, 2022 | December 1, 2025 |
| NCT04804007 | Recruiting | Phase 2 | Maintenance Oral Etoposide or Observation Following High-dose Chemo for GCT | March 3, 2021 | December 2028 |
| NCT04876456 | Recruiting | Phase 2 | A Phase II Trial of Cabozantinib With Patients With Refractory GCTs | June 10, 2021 | December 2025 |
| NCT05259605 | Recruiting | Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification | March 28, 2023 | December 15, 2026 | |
| NCT05394675 | Recruiting | Phase 1 | A Study of DS-9606a in Patients With Advanced Solid Tumors | May 31, 2022 | February 19, 2026 |
| NCT05502224 | Recruiting | N/A | Multidisciplinary Approach to Fatigue | August 19, 2022 | September 2027 |
| NCT05564026 | Recruiting | Molecular Epidemiology of Pediatric Germ Cell Tumors | April 12, 2023 | June 30, 2027 | |
| NCT05634785 | Recruiting | Phase 2 | CD30 CAR for CD30+ NSGCT | December 9, 2022 | December 2026 |
| NCT05672043 | Recruiting | Genetic and Molecular Risk Profiles of Pediatric Malignant Brain Tumors in China | January 1, 2023 | December 31, 2032 | |
| NCT05874063 | Recruiting | Phase 3 | Thromboprophylaxis in Good and Intermediate Prognosis Advanced Germ Cell Tumors | October 17, 2023 | February 2028 |
| NCT05889585 | Recruiting | Morbidity, Long-term Side Effects and Quality of Life in Germ-cell Tumor Long Survivors Treated With High-dose Chemotherapy and Autologous Stem Cell Transplant | May 31, 2023 | May 2024 | |
| NCT06133543 | Recruiting | N/A | Robot-assisted ICG-guided Sentinel Node Biopsy in Testicular Cancer | September 6, 2023 | October 31, 2026 |
| NCT06276491 | Recruiting | Phase 1 | Phase 1, Safety and Tolerability Study of XmAb®541 in Advanced Solid Tumors | April 4, 2024 | December 2028 |
| NCT06418789 | Recruiting | Phase 2 | High-dose Chemotherapy as Second-line Drug Therapy for Relapsed Germ Cell Tumors | March 1, 2024 | March 1, 2029 |
| NCT03618381 | Recruiting | Phase 1 | EGFR806 CAR T Cell Immunotherapy for Recurrent/Refractory Solid Tumors in Children and Young Adults | June 18, 2019 | June 2040 |
| NCT04185038 | Recruiting | Phase 1 | Study of B7-H3-Specific CAR T Cell Locoregional Immunotherapy for Diffuse Intrinsic Pontine Glioma/Diffuse Midline Glioma and Recurrent or Refractory Pediatric Central Nervous System Tumors | December 11, 2019 | May 2041 |
| NCT04308330 | Recruiting | Phase 1 | Vorinostat in Combination With Chemotherapy in Relapsed/Refractory Solid Tumors and CNS Malignancies | March 17, 2017 | December 31, 2024 |
| NCT02988843 | Terminated | Phase 2 | Study of Brentuximab Vedotin And Bevacizumab In Refractory CD-30 Positive Germ Cell Tumors | March 29, 2017 | December 15, 2019 |
| NCT00198172 | Terminated | Phase 2 | Phase II Study of Cisplatin Plus Epirubicin Salvage Chemo in Refractory Germ Cell Tumors | October 2000 | March 2007 |
| NCT02624388 | Terminated | Phase 2 | Study of Genistein in Pediatric Oncology Patients (UVA-Gen001) | August 2016 | September 2021 |
| NCT00369291 | Terminated | Phase 1 | CpG 7909 in Treating Patients Who Have Undergone Autologous Stem Cell Transplant | September 2003 | May 2010 |
| NCT03081923 | Terminated | Phase 2 | Durvalumab Alone or With Tremelimumab in Refractory Germ Cell Tumors | February 1, 2017 | December 6, 2019 |
| NCT01049230 | Unknown status | N/A | Proton Beam Radiation Therapy for Central Nervous System (CNS) Germ Cell Tumors | June 2010 | August 2022 |
| NCT05179850 | Unknown status | Computer Aided Diagnostic Tool on Computed Tomography Images for Diagnosis of Retroperitoneal Tumor in Children | January 1, 2021 | December 31, 2023 | |
| NCT00179816 | Unknown status | Phase 1/Phase 2 | Tandem Peripheral Blood Stem Cell (PBSC) Rescue for High Risk Solid Tumors | April 1999 | September 2012 |
| NCT00983398 | Unknown status | Phase 1/Phase 2 | Melphalan, Carboplatin, Mannitol, and Sodium Thiosulfate in Treating Patients With Recurrent or Progressive CNS Embryonal or Germ Cell Tumors | July 9, 2009 | December 31, 2022 |
| NCT00127049 | Unknown status | Phase 2 | Trial of Gemcitabine, Cisplatin, and Ifosfamide in Patients With Relapsed Non-Seminomatous Germ-Cell Tumors | December 2004 | |
| NCT03476070 | Unknown status | Adolescent and Young Adult Cancer Patients: Cognitive Toxicity on Survivorship (ACTS) | June 18, 2018 | September 1, 2022 | |
| NCT02582697 | Unknown status | Phase 3 | Accelerated v's Standard BEP Chemotherapy for Patients With Intermediate and Poor-risk Metastatic Germ Cell Tumours | February 2014 | July 2023 |
| NCT03868176 | Unknown status | Study Evaluating the Impact of Short Message Service on Compliance With Surveillance of Patients With Germ-cell Tumors | February 28, 2019 | August 2021 | |
| NCT01966913 | Unknown status | Phase 1/Phase 2 | Salvage Chemotherapy for Poor Prognosis Germ Cell Tumors | April 2012 | September 2020 |
| NCT03960151 | Withdrawn | Phase 2 | Rolapitant Plus Olanzapine in Multiday Cisplatin Chemotherapy | May 2018 | March 2022 |