chrX:47582408:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chrX:47,441,807-47,446,188 
hg38 chrX:47,582,408-47,586,789

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.007 squamous cell carcinoma NA BeFree,LHGDN Detail
<0.001 Cardiomyopathy, Dilated NA BeFree Detail
<0.001 Cardiovascular Diseases However, until now only a handful number of genetic variants were reported to be... BeFree 25169573 Detail
0.003 carotid stenosis NA BeFree,LHGDN Detail
<0.001 celiac disease NA BeFree Detail
<0.001 CNS disorder NA BeFree Detail
<0.001 Central Nervous System Infection NA BeFree Detail
0.083 intracranial aneurysm NA BeFree,LHGDN,RGD Detail
<0.001 Malignant tumor of cervix NA BeFree Detail
0.080 cholestasis NA RGD Detail
0.002 chorioamnionitis NA GAD Detail
<0.001 choriocarcinoma NA BeFree Detail
0.006 ulcerative colitis NA BeFree,LHGDN Detail
0.003 Colonic Neoplasms NA BeFree,LHGDN Detail
0.005 colorectal carcinoma TIMP-1 expression in human colorectal cancer is associated with SMAD3 gene expre... BeFree 25532000 Detail
0.012 Colorectal Neoplasms NA BeFree,LHGDN Detail
0.003 Febrile Convulsions NA BeFree,LHGDN Detail
<0.001 Coronary Arteriosclerosis NA BeFree Detail
0.005 Coronary heart disease NA BeFree,GAD Detail
0.006 Crohn Disease NA BeFree,GAD,LHGDN Detail
0.003 Dermatitis, Atopic NA LHGDN Detail
<0.001 Stasis dermatitis NA BeFree Detail
<0.001 scleroderma NA BeFree Detail
0.001 Diabetes However, until now only a handful number of genetic variants were reported to be... BeFree 25169573 Detail
0.001 diabetes mellitus However, until now only a handful number of genetic variants were reported to be... BeFree 25169573 Detail
0.200 Diabetes Mellitus, Experimental NA CTD_human,RGD Detail
0.001 Diabetes Mellitus, Insulin-Dependent NA BeFree Detail
0.121 Diabetes Mellitus, Non-Insulin-Dependent The presence of type 2 diabetes associated with 3.2-fold increased PAI-1 express... BeFree,CTD_human 25496999 Detail
0.002 Diabetic Angiopathies NA GAD Detail
0.001 Diabetic Nephropathy NA BeFree Detail
<0.001 diabetic retinopathy NA BeFree Detail
0.003 Muscular Dystrophy, Duchenne NA BeFree,LHGDN Detail
0.003 duodenal ulcer NA BeFree,GAD Detail
0.003 Edema NA LHGDN Detail
<0.001 encephalitis NA BeFree Detail
0.002 Endometrial Neoplasms NA GAD Detail
0.003 endometriosis NA BeFree,LHGDN Detail
0.002 Fetal Membranes, Premature Rupture NA GAD Detail
<0.001 breast fibrocystic disease NA BeFree Detail
0.005 Fibrosis NA LHGDN Detail
0.001 glioblastoma NA BeFree Detail
0.003 Glioma NA BeFree Detail
0.003 glomerulonephritis NA BeFree,LHGDN Detail
0.120 IgA glomerulonephritis NA CTD_human Detail
<0.001 goiter NA BeFree Detail
0.002 Graft Occlusion, Vascular NA GAD Detail
0.200 Heart Diseases NA BeFree,CTD_human,RGD Detail
0.081 Heart failure NA BeFree,RGD Detail
<0.001 congestive heart failure NA BeFree Detail
0.120 heart valve disease NA CTD_human Detail
<0.001 hemochromatosis NA BeFree Detail
0.003 Hemorrhage NA LHGDN Detail
0.120 Hepatolenticular Degeneration NA CTD_human Detail
<0.001 Hepatosplenomegaly NA BeFree Detail
<0.001 HIV Infections NA BeFree Detail
0.003 Hodgkin Disease NA BeFree,LHGDN Detail
0.003 Hypercholesterolemia, Familial NA BeFree,LHGDN Detail
0.083 Hypertensive disease The presence of type 2 diabetes associated with 3.2-fold increased PAI-1 express... BeFree,LHGDN,RGD 25496999 Detail
0.003 Hypertension, Portal NA LHGDN Detail
0.123 Inflammation NA CTD_human,LHGDN Detail
0.004 Inflammatory Bowel Diseases NA BeFree,LHGDN Detail
<0.001 ischemia NA BeFree Detail
<0.001 Keloid NA BeFree Detail
0.001 keratoconus NA BeFree Detail
0.003 Kidney Diseases NA BeFree,LHGDN Detail
0.001 Kidney Failure, Chronic NA BeFree Detail
0.002 Premature Obstetric Labor NA GAD Detail
<0.001 Fibroid Tumor EPO mRNA expression was detected in 108 of 114, or 95%, of the leiomyomas. BeFree 25724399 Detail
<0.001 leukemia NA BeFree Detail
0.001 Acute Erythroblastic Leukemia NA BeFree Detail
<0.001 Acute lymphocytic leukemia NA BeFree Detail
<0.001 Leukemia, Lymphocytic, Acute, L1 NA BeFree Detail
<0.001 Leukemia, Myelocytic, Acute NA BeFree Detail
0.003 myeloid leukemia NA LHGDN Detail
<0.001 Myeloid Leukemia, Chronic NA BeFree Detail
0.003 liver cirrhosis NA BeFree,GAD Detail
0.120 Liver Cirrhosis, Alcoholic NA CTD_human Detail
0.200 Liver Cirrhosis, Experimental NA BeFree,CTD_human,RGD Detail
<0.001 Liver diseases NA BeFree Detail
0.001 Liver neoplasms NA BeFree Detail
0.006 Chronic Obstructive Airway Disease A significantly higher TIMP1 level in blood serum was observed in the COPD + can... BeFree,GAD,LHGDN 25292126 Detail
0.006 Chronic Obstructive Airway Disease Effect of Liuweibuqi capsule, a Chinese patent medicine, on the JAK1/STAT3 pathw... BeFree,GAD,LHGDN 25842729 Detail
<0.001 Lupus Erythematosus, Systemic NA BeFree Detail
0.007 lymphoma NA BeFree,LHGDN Detail
0.003 Lymphoma, Non-Hodgkin NA BeFree,GAD Detail
<0.001 Lymphoproliferative Disorders NA BeFree Detail
<0.001 Mycetoma NA BeFree Detail
0.003 Malignant neoplasm of stomach Real-Time PCR and western blot showed increasing of HIF-1α in mRNA and protein l... BeFree 24927122 Detail
<0.001 Marfan syndrome NA BeFree Detail
0.005 melanoma NA BeFree,LHGDN Detail
0.003 meningioma NA BeFree,LHGDN Detail
0.003 viral meningitis NA BeFree,LHGDN Detail
<0.001 Metabolic Diseases NA BeFree Detail
0.002 Metaplasia NA GAD Detail
<0.001 Mixed Salivary Gland Tumor NA BeFree Detail
<0.001 Moyamoya disease NA BeFree Detail
0.003 Mucocutaneous Lymph Node Syndrome NA LHGDN Detail
0.004 multiple myeloma NA BeFree,LHGDN Detail
0.005 multiple sclerosis NA BeFree,LHGDN Detail
<0.001 muscular dystrophy NA BeFree Detail
0.006 myocardial infarction Our findings indicate that overexpression of MMP-9 and TIMPs in blood mononuclea... BeFree,GAD,LHGDN 25153995 Detail
<0.001 Nasal Polyps NA BeFree Detail
<0.001 Necrotizing Scleritis NA BeFree Detail
0.123 Neoplasm Invasiveness NA CTD_human,LHGDN Detail
0.022 Neoplasm Metastasis Our findings identify hRAB37 as a novel metastasis suppressor Rab that functions... BeFree,LHGDN 25183545 Detail
0.022 Neoplasm Metastasis In summary, this study presents novel functions of TIMP-1 in promoting cancer me... BeFree,LHGDN 25578494 Detail
<0.001 nephroblastoma NA BeFree Detail
<0.001 nervous system disorder NA BeFree Detail
0.003 Neuromuscular Diseases NA LHGDN Detail
<0.001 obesity NA BeFree Detail
0.121 oral submucous fibrosis NA BeFree,CTD_human Detail
0.001 Degenerative polyarthritis NA BeFree Detail
<0.001 osteosarcoma NA BeFree Detail
0.001 ovarian carcinoma NA BeFree Detail
<0.001 Pancreatic Neoplasm NA BeFree Detail
0.001 periodontitis NA BeFree Detail
<0.001 pituitary adenoma NA BeFree Detail
<0.001 Pituitary Diseases NA BeFree Detail
<0.001 Pleural effusion disorder NA BeFree Detail
<0.001 pneumonia NA BeFree Detail
0.003 polycystic ovary syndrome NA LHGDN Detail
0.002 polycythemia NA BeFree Detail
<0.001 polycythemia vera NA BeFree Detail
0.002 pre-eclampsia NA GAD Detail
<0.001 progeria NA BeFree Detail
0.003 Prostatic Neoplasms NA LHGDN Detail
0.120 pulmonary fibrosis NA BeFree,CTD_human Detail
0.005 pyelonephritis NA LHGDN Detail
<0.001 Refractive Errors NA BeFree Detail
<0.001 kidney failure NA BeFree Detail
<0.001 Respiratory Syncytial Virus Infections NA BeFree Detail
<0.001 retinal degeneration NA BeFree Detail
<0.001 Retinal Diseases However, until now only a handful number of genetic variants were reported to be... BeFree 25169573 Detail
0.011 systemic scleroderma In contrast, TIMP-1 levels were higher in SSc but DHLA had minimal effect. BeFree,GAD,LHGDN 25123250 Detail
0.011 systemic scleroderma miR-29a repressed TAB1-mediated TIMP-1 production in dermal fibroblasts, demonst... BeFree,GAD,LHGDN 25549087 Detail
0.003 Sclerosis NA LHGDN Detail
0.003 Skin Neoplasms NA LHGDN Detail
0.003 ankylosing spondylitis NA BeFree,GAD Detail
0.003 Stomach Neoplasms NA LHGDN Detail
0.080 gastric ulcer NA RGD Detail
0.080 Cerebrovascular accident Our results provide evidence for a positive effect of simvastatin on the MMP met... BeFree,RGD 25476155 Detail
0.003 subacute sclerosing panencephalitis NA LHGDN Detail
<0.001 Subarachnoid Hemorrhage NA BeFree Detail
0.004 Thyroid Neoplasm NA BeFree,LHGDN Detail
<0.001 tuberculosis NA BeFree Detail
<0.001 Tuberculosis, Meningeal NA BeFree Detail
<0.001 Uterine Fibroids EPO mRNA expression was detected in 108 of 114, or 95%, of the leiomyomas. BeFree 25724399 Detail
0.120 Varicosity NA BeFree,CTD_human Detail
0.200 Vascular Diseases NA CTD_human,RGD Detail
<0.001 Virus Diseases NA BeFree Detail
<0.001 Werner syndrome NA BeFree Detail
0.001 Wiskott-Aldrich syndrome NA BeFree Detail
<0.001 epidermolysis bullosa acquisita NA BeFree Detail
<0.001 Hallopeau-Siemens Disease NA BeFree Detail
0.005 Helicobacter Infections NA BeFree,GAD Detail
<0.001 Ichthyosis, X-Linked NA BeFree Detail
<0.001 B-Cell Lymphomas NA BeFree Detail
<0.001 High Grade Lymphoma (neoplasm) NA BeFree Detail
<0.001 Lymphoma, Large-Cell, Follicular NA BeFree Detail
<0.001 severe combined immunodeficiency NA BeFree Detail
0.003 Meningitis, Bacterial NA LHGDN Detail
<0.001 Depressive Symptoms Our findings indicate that overexpression of MMP-9 and TIMPs in blood mononuclea... BeFree 25153995 Detail
<0.001 benign neoplasm NA BeFree Detail
0.003 Epstein-Barr Virus Infections NA LHGDN Detail
<0.001 Left Ventricular Hypertrophy NA BeFree Detail
<0.001 Squamous cell carcinoma of lung NA BeFree Detail
0.002 Premature Birth NA GAD Detail
<0.001 renal fibrosis NA BeFree Detail
<0.001 Adenocarcinoma of lung (disorder) Down-regulation of TIMP-1 inhibits cell migration, invasion, and metastatic colo... BeFree 25578494 Detail
<0.001 esophageal carcinoma NA BeFree Detail
<0.001 Idiopathic pulmonary hypertension NA BeFree Detail
<0.001 Familial erythrocytosis NA BeFree Detail
<0.001 Malignant neoplasm of gallbladder NA BeFree Detail
0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 Corneal pannus NA BeFree Detail
0.081 Intervertebral Disc Degeneration NA BeFree,RGD Detail
<0.001 Cicatrix, Hypertrophic NA BeFree Detail
0.011 Aortic Aneurysm, Abdominal NA BeFree,GAD,LHGDN Detail
0.002 Tumor Progression Only recently, TIMP-1 has been revealed as a signalling molecule that can regula... BeFree 25263437 Detail
0.002 Tumor Progression Tissue inhibitor of metalloproteinases-1 is a glycoprotein, which regulates meta... BeFree 25608838 Detail
<0.001 Microinvasive tumor NA BeFree Detail
<0.001 Anaplastic carcinoma NA BeFree Detail
<0.001 Undifferentiated carcinoma NA BeFree Detail
<0.001 Diabetic Foot This work studied the expression of selected MMP and tissue inhibitor of metallo... BeFree 25168880 Detail
0.004 Ki-1+ Anaplastic Large Cell Lymphoma NA BeFree,LHGDN Detail
<0.001 Adenomatous Polyps NA BeFree Detail
0.002 pancreatic carcinoma NA BeFree Detail
<0.001 Colitis, Collagenous NA BeFree Detail
0.001 Papillary thyroid carcinoma NA BeFree Detail
<0.001 bone destruction NA BeFree Detail
0.005 Fibrosis, Liver Hepatocyte growth factor (HGF) gene transfer inhibits liver fibrosis by regulati... BeFree 25380300 Detail
0.005 Fibrosis, Liver Serum from patients with liver fibrosis was examined for adiponectin and tissue ... BeFree 25575598 Detail
<0.001 Interstitial fibrosis NA BeFree Detail
0.001 Malignant neoplasm of lung This new pro-tumourigenic signalling function of TIMP-1 may explain why elevated... BeFree 25263437 Detail
0.001 Malignant neoplasm of lung We compared the frequency of single nucleotide polymorphisms in genes coding for... BeFree 25292126 Detail
0.001 Malignant neoplasm of lung Tissue inhibitor metalloproteinase-1 (TIMP-1) is clinically associated with a po... BeFree 25578494 Detail
<0.001 age related macular degeneration NA BeFree Detail
0.080 Hyperoxia NA RGD Detail
0.003 Sepsis NA LHGDN Detail
<0.001 Childhood asthma NA BeFree Detail
<0.001 Cerebral Vasospasm NA BeFree Detail
<0.001 Ichthyosis linearis circumflexa Interestingly, the highest level of EPO/% retic ratio as indicated for EPO non-r... BeFree 25477265 Detail
<0.001 Chronic Periodontitis NA BeFree Detail
<0.001 Intestinal metaplasia of gastric mucosa NA BeFree Detail
<0.001 Ocular albinism, type II NA BeFree Detail
<0.001 Endometrioma NA BeFree Detail
<0.001 Impaired glucose tolerance NA BeFree Detail
<0.001 Tuberculosis, Central Nervous System NA BeFree Detail
<0.001 Carcinoma breast stage IV NA BeFree Detail
<0.001 Metastatic melanoma NA BeFree Detail
<0.001 Invasive lobular breast carcinoma NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus The aim of this study was to investigate the role of RUNX3 in esophageal squamou... BeFree 25428380 Detail
<0.001 Adenocarcinoma Of Esophagus NA BeFree Detail
<0.001 laryngeal squamous cell carcinoma NA BeFree Detail
<0.001 Vascular Neoplasms NA BeFree Detail
<0.001 cervix carcinoma NA BeFree Detail
0.004 Restenosis NA BeFree,GAD Detail
<0.001 Chronic ulcer NA BeFree Detail
<0.001 Superficial ulcer NA BeFree Detail
<0.001 anaplastic astrocytoma NA BeFree Detail
<0.001 pilocytic astrocytoma NA BeFree Detail
<0.001 X-linked retinitis pigmentosa NA BeFree Detail
<0.001 Glaucoma, Primary Open Angle NA BeFree Detail
<0.001 Stable angina NA BeFree Detail
<0.001 Chronic liver disease NA BeFree Detail
<0.001 sialuria NA BeFree Detail
<0.001 Benign neoplasm of breast NA BeFree Detail
0.001 Malignant neoplasm of pancreas NA BeFree Detail
<0.001 Isolated aortic stenosis NA BeFree Detail
<0.001 Ischemic cardiomyopathy NA BeFree Detail
0.002 Malignant neoplasm of prostate Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction... BeFree 25623427 Detail
<0.001 Hereditary gingival fibromatosis NA BeFree Detail
<0.001 Lipodermatosclerosis NA BeFree Detail
<0.001 endometrial carcinoma NA BeFree Detail
0.003 Secondary malignant neoplasm of liver NA BeFree Detail
0.003 dementia NA LHGDN Detail
<0.001 Necrotizing Enterocolitis NA BeFree Detail
<0.001 Fibrosis of bile duct NA BeFree Detail
<0.001 acute pyelonephritis NA BeFree Detail
<0.001 Metabolic syndrome X In MetS; the T-allele associated with 5.5 fold increase in event rate (p<0.0001)... BeFree 25191702 Detail
0.003 Hepatitis B, Chronic NA LHGDN Detail
0.003 Hepatitis C, Chronic NA BeFree,GAD Detail
<0.001 Thyroid carcinoma NA BeFree Detail
<0.001 Malignant glioma NA BeFree Detail
<0.001 Squamous cell carcinoma of mouth NA BeFree Detail
<0.001 Osteosarcoma of bone NA BeFree Detail
<0.001 Carcinogenesis NA BeFree Detail
<0.001 hyperhomocysteinemia NA BeFree Detail
<0.001 Leukemogenesis NA BeFree Detail
0.003 prostate carcinoma Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction... BeFree 25623427 Detail
<0.001 Epithelial ovarian cancer NA BeFree Detail
<0.001 invasive cancer NA BeFree Detail
0.010 breast carcinoma Our findings highlight TIMP-3 induction as a key epigenetic event modulated by G... BeFree 24481780 Detail
0.010 breast carcinoma Angiogenic cytokines which are known to regulate tumorigenicity and angiogenesis... BeFree 24941346 Detail
0.010 breast carcinoma Predictive role of HER2/neu, topoisomerase-II-alpha, and tissue inhibitor of met... BeFree 25721604 Detail
<0.001 polycythemia vera As compared to their JAK2 V617F negative counterparts, the JAK2 V617F positive p... BeFree 18616871 Detail
0.002 Carcinoma of lung This new pro-tumourigenic signalling function of TIMP-1 may explain why elevated... BeFree 25263437 Detail
0.002 Carcinoma of lung We compared the frequency of single nucleotide polymorphisms in genes coding for... BeFree 25292126 Detail
0.002 Carcinoma of lung Tissue inhibitor metalloproteinase-1 (TIMP-1) is clinically associated with a po... BeFree 25578494 Detail
<0.001 Malignant neoplasm of gastrointestinal tract NA BeFree Detail
<0.001 CNS metastases NA BeFree Detail
0.003 Secondary malignant neoplasm of lymph node NA BeFree Detail
<0.001 Community acquired pneumonia NA BeFree Detail
0.003 colon carcinoma NA BeFree Detail
0.004 stomach carcinoma Real-Time PCR and western blot showed increasing of HIF-1α in mRNA and protein l... BeFree 24927122 Detail
<0.001 Carcinoma of bladder NA BeFree Detail
<0.001 Brain Tumor, Primary NA BeFree Detail
<0.001 Helicobacter pylori infection NA BeFree Detail
<0.001 Adenoviral infections NA BeFree Detail
0.005 Pregnancy associated hypertension NA LHGDN Detail
<0.001 Post MI NA BeFree Detail
<0.001 Borderline ovarian tumour NA BeFree Detail
<0.001 Muscle fibrosis NA BeFree Detail
<0.001 Advanced cancer NA BeFree Detail
<0.001 Asthma chronic NA BeFree Detail
<0.001 Cardiomyopathies NA BeFree Detail
<0.001 Stromal Neoplasm NA BeFree Detail
0.003 ovarian neoplasm NA BeFree,LHGDN Detail
<0.001 Metastatic Prostate Carcinoma NA BeFree Detail
<0.001 precancerous lesions NA BeFree Detail
<0.001 Acute coronary syndrome NA BeFree Detail
<0.001 Primary infection NOS NA BeFree Detail
<0.001 Colorectal cancer metastatic TIMP-1 and CEA as biomarkers in third-line treatment with irinotecan and cetuxim... BeFree 25608838 Detail
<0.001 Arthritis, Collagen-Induced NA BeFree Detail
<0.001 Sialic Acid Storage Disease, Finnish Type (disorder) NA BeFree Detail
0.003 Malignant neoplasm of ovary NA BeFree,GAD Detail
<0.001 Renal anemia NA BeFree Detail
<0.001 Mammary Carcinoma, Human NA BeFree Detail
0.002 Stenosis NA GAD Detail
<0.001 Acral pseudolymphomatous angiokeratoma of children (APACHE) NA BeFree Detail
<0.001 Adenoma of large intestine NA BeFree Detail
<0.001 chronic venous insufficiency NA BeFree Detail
<0.001 Adenocarcinoma of large intestine The RPL35, RPS23 and TIMP1 genes were found to be overexpressed in both early an... BeFree 25107436 Detail
<0.001 autoimmune lymphoproliferative syndrome NA BeFree Detail
<0.001 Epithelioma NA BeFree Detail
<0.001 Cardiomyopathy, Familial Idiopathic NA BeFree Detail
<0.001 Diabetic foot ulcer This work studied the expression of selected MMP and tissue inhibitor of metallo... BeFree 25168880 Detail
0.012 Mammary Neoplasms NA BeFree,LHGDN Detail
<0.001 Breast Cancer Model NA BeFree Detail
<0.001 Tumor Angiogenesis MMPs and TIMPs play important roles in tumor angiogenesis and invasion. BeFree 25533828 Detail
0.004 colorectal cancer TIMP-1 expression in human colorectal cancer is associated with SMAD3 gene expre... BeFree 25532000 Detail
<0.001 Cirrhosis NA BeFree Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
<0.001 Aggressive periodontitis, generalized Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene pol... BeFree 24283658 Detail
0.120 Female Urogenital Diseases NA CTD_human Detail
<0.001 Meningioma, benign, no ICD-O subtype NA BeFree Detail
<0.001 Idiopathic Pulmonary Fibrosis NA BeFree Detail
<0.001 THROMBOCYTOPENIA 1 (disorder) NA BeFree Detail
<0.001 NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A NA BeFree Detail
<0.001 Dyssegmental dysplasia NA BeFree Detail
<0.001 uterine corpus cancer NA BeFree Detail
<0.001 coronary artery disease NA BeFree Detail
<0.001 Parvovirus B19 (disease) NA BeFree Detail
<0.001 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree Detail
<0.001 Postmenopausal endometrium NA BeFree Detail
0.014 liver carcinoma NA BeFree,LHGDN Detail
<0.001 Destructive Arthritis NA BeFree Detail
<0.001 Mycetoma of foot NA BeFree Detail
<0.001 RETINITIS PIGMENTOSA 2 (disorder) NA BeFree Detail
0.002 Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified NA GAD Detail
<0.001 Moyamoya disease 1 NA BeFree Detail
<0.001 Pulmonary arterial hypertension NA BeFree Detail
<0.001 Valvular disease NA BeFree Detail
0.003 Juvenile arthritis NA LHGDN Detail
0.003 Infection NA LHGDN Detail
<0.001 Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia NA BeFree Detail
<0.001 Portal fibrosis NA BeFree Detail
0.002 adenocarcinoma NA BeFree Detail
<0.001 adenoma NA BeFree Detail
0.005 Alzheimer's disease NA GAD,LHGDN Detail
<0.001 amyloidosis NA BeFree Detail
0.003 amyotrophic lateral sclerosis NA BeFree,LHGDN Detail
0.001 anemia NA BeFree Detail
0.003 Aneurysm NA BeFree,GAD Detail
<0.001 Angina, Unstable NA BeFree Detail
0.001 aortic aneurysm NA BeFree Detail
0.120 aortic valve insufficiency NA CTD_human Detail
<0.001 aortic valve stenosis NA BeFree Detail
<0.001 arteriosclerosis NA BeFree Detail
<0.001 Arteriovenous fistula NA BeFree Detail
0.003 arthritis NA BeFree,GAD Detail
<0.001 Arthritis, Psoriatic NA BeFree Detail
0.004 rheumatoid arthritis NA BeFree,GAD Detail
0.006 asthma NA BeFree,GAD,LHGDN Detail
0.001 Astrocytoma NA BeFree Detail
0.004 atherosclerosis NA BeFree,LHGDN Detail
<0.001 Autoimmune Diseases NA BeFree Detail
<0.001 Melanoma, B16 NA BeFree Detail
0.003 biliary atresia NA BeFree,LHGDN Detail
<0.001 Malignant neoplasm of urinary bladder NA BeFree Detail
<0.001 Brain Neoplasms NA BeFree Detail
0.009 Malignant neoplasm of breast Our findings highlight TIMP-3 induction as a key epigenetic event modulated by G... BeFree 24481780 Detail
0.009 Malignant neoplasm of breast Angiogenic cytokines which are known to regulate tumorigenicity and angiogenesis... BeFree 24941346 Detail
0.009 Malignant neoplasm of breast Predictive role of HER2/neu, topoisomerase-II-alpha, and tissue inhibitor of met... BeFree 25721604 Detail
0.003 bronchiolitis obliterans NA LHGDN Detail
0.005 bronchopulmonary dysplasia NA LHGDN Detail
<0.001 Burkitt lymphoma NA BeFree Detail
0.120 calcinosis NA CTD_human Detail
0.003 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
0.002 Rectal Carcinoma NA GAD Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
0.002 Non-small cell lung carcinoma NA BeFree Detail
0.002 renal cell carcinoma NA BeFree Detail
Annotation

Annotations

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However, until now only a handful number of genetic variants were reported to be associated with eit... DisGeNET Detail
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TIMP-1 expression in human colorectal cancer is associated with SMAD3 gene expression levels: a pilo... DisGeNET Detail
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However, until now only a handful number of genetic variants were reported to be associated with eit... DisGeNET Detail
However, until now only a handful number of genetic variants were reported to be associated with eit... DisGeNET Detail
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The presence of type 2 diabetes associated with 3.2-fold increased PAI-1 expression (adjusted p=0.03... DisGeNET Detail
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The presence of type 2 diabetes associated with 3.2-fold increased PAI-1 expression (adjusted p=0.03... DisGeNET Detail
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EPO mRNA expression was detected in 108 of 114, or 95%, of the leiomyomas. DisGeNET Detail
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A significantly higher TIMP1 level in blood serum was observed in the COPD + cancer group than in th... DisGeNET Detail
Effect of Liuweibuqi capsule, a Chinese patent medicine, on the JAK1/STAT3 pathway and MMP9/TIMP1 in... DisGeNET Detail
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Real-Time PCR and western blot showed increasing of HIF-1α in mRNA and protein levels as well as TIM... DisGeNET Detail
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Our findings indicate that overexpression of MMP-9 and TIMPs in blood mononuclear cells and elevated... DisGeNET Detail
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Our findings identify hRAB37 as a novel metastasis suppressor Rab that functions through the TIMP1-M... DisGeNET Detail
In summary, this study presents novel functions of TIMP-1 in promoting cancer metastasis and suggest... DisGeNET Detail
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However, until now only a handful number of genetic variants were reported to be associated with eit... DisGeNET Detail
In contrast, TIMP-1 levels were higher in SSc but DHLA had minimal effect. DisGeNET Detail
miR-29a repressed TAB1-mediated TIMP-1 production in dermal fibroblasts, demonstrating that miR-29a ... DisGeNET Detail
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Our results provide evidence for a positive effect of simvastatin on the MMP metabolism in human BME... DisGeNET Detail
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EPO mRNA expression was detected in 108 of 114, or 95%, of the leiomyomas. DisGeNET Detail
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Our findings indicate that overexpression of MMP-9 and TIMPs in blood mononuclear cells and elevated... DisGeNET Detail
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Down-regulation of TIMP-1 inhibits cell migration, invasion, and metastatic colonization in lung ade... DisGeNET Detail
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Only recently, TIMP-1 has been revealed as a signalling molecule that can regulate cancer progressio... DisGeNET Detail
Tissue inhibitor of metalloproteinases-1 is a glycoprotein, which regulates metalloproteinases and m... DisGeNET Detail
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This work studied the expression of selected MMP and tissue inhibitor of metalloproteinases (TIMP) g... DisGeNET Detail
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Hepatocyte growth factor (HGF) gene transfer inhibits liver fibrosis by regulating aberrant cellular... DisGeNET Detail
Serum from patients with liver fibrosis was examined for adiponectin and tissue inhibitor of metallo... DisGeNET Detail
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This new pro-tumourigenic signalling function of TIMP-1 may explain why elevated TIMP-1 levels in lu... DisGeNET Detail
We compared the frequency of single nucleotide polymorphisms in genes coding for matrix proteinases ... DisGeNET Detail
Tissue inhibitor metalloproteinase-1 (TIMP-1) is clinically associated with a poor prognosis for var... DisGeNET Detail
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Interestingly, the highest level of EPO/% retic ratio as indicated for EPO non-responder was detecte... DisGeNET Detail
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The aim of this study was to investigate the role of RUNX3 in esophageal squamous cell carcinoma (ES... DisGeNET Detail
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Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating mac... DisGeNET Detail
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In MetS; the T-allele associated with 5.5 fold increase in event rate (p<0.0001), increased with num... DisGeNET Detail
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Targeting TR4 nuclear receptor suppresses prostate cancer invasion via reduction of infiltrating mac... DisGeNET Detail
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Our findings highlight TIMP-3 induction as a key epigenetic event modulated by GTPs in restoring the... DisGeNET Detail
Angiogenic cytokines which are known to regulate tumorigenicity and angiogenesis, such as GM-CSF, IG... DisGeNET Detail
Predictive role of HER2/neu, topoisomerase-II-alpha, and tissue inhibitor of metalloproteinases (TIM... DisGeNET Detail
As compared to their JAK2 V617F negative counterparts, the JAK2 V617F positive patients had PV-like ... DisGeNET Detail
This new pro-tumourigenic signalling function of TIMP-1 may explain why elevated TIMP-1 levels in lu... DisGeNET Detail
We compared the frequency of single nucleotide polymorphisms in genes coding for matrix proteinases ... DisGeNET Detail
Tissue inhibitor metalloproteinase-1 (TIMP-1) is clinically associated with a poor prognosis for var... DisGeNET Detail
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Real-Time PCR and western blot showed increasing of HIF-1α in mRNA and protein levels as well as TIM... DisGeNET Detail
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TIMP-1 and CEA as biomarkers in third-line treatment with irinotecan and cetuximab for metastatic co... DisGeNET Detail
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The RPL35, RPS23 and TIMP1 genes were found to be overexpressed in both early and advanced stage col... DisGeNET Detail
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This work studied the expression of selected MMP and tissue inhibitor of metalloproteinases (TIMP) g... DisGeNET Detail
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MMPs and TIMPs play important roles in tumor angiogenesis and invasion. DisGeNET Detail
TIMP-1 expression in human colorectal cancer is associated with SMAD3 gene expression levels: a pilo... DisGeNET Detail
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Matrix metalloproteinase (MMP)-8 and tissue inhibitor of MMP-1 (TIMP-1) gene polymorphisms in genera... DisGeNET Detail
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Our findings highlight TIMP-3 induction as a key epigenetic event modulated by GTPs in restoring the... DisGeNET Detail
Angiogenic cytokines which are known to regulate tumorigenicity and angiogenesis, such as GM-CSF, IG... DisGeNET Detail
Predictive role of HER2/neu, topoisomerase-II-alpha, and tissue inhibitor of metalloproteinases (TIM... DisGeNET Detail
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Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386626619 dbSNP
Genome
hg38
Position
chrX:47,582,408-47,586,789
Variant Type
snv
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