Ischemic cardiomyopathy

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Information
Disease name
Ischemic cardiomyopathy
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03231189 Active, not recruiting Cardiac MRI in Front Line for the Diagnosis of Coronary Artery Disease as the Etiology of Left Ventricular Dysfunction May 15, 2018 December 2023
NCT03845127 Active, not recruiting N/A Randomized Evaluation and Verification of Ventricular Enhancement January 1, 2020 December 31, 2027
NCT03493516 Active, not recruiting Prediction of ARrhythmic Events With Positron Emission Tomography II April 8, 2018 December 31, 2025
NCT04489355 Active, not recruiting The Effectiveness of Surgical Treatment of Patients With Ischemic Cardiomyopathy January 28, 2013 May 1, 2024
NCT05745571 Active, not recruiting N/A Molecular Pathways of Cardiac Remodellation in Patients With Acute and Chronic Left Ventricular Disfunction January 7, 2019 December 10, 2023
NCT00665301 Completed Cardiac Output Pulmonary Arterial Catheter Compared to FloWave™ 1000 March 2008 June 2008
NCT00824005 Completed Phase 2 Effectiveness of Stem Cell Treatment for Adults With Ischemic Cardiomyopathy (The FOCUS Study) March 2009 May 2012
NCT00896142 Completed Optima Coronary Artery Disease (CAD) (Optimal Mechanical Evaluation) October 2006
NCT04829955 Completed N/A Eccentric Manual Resistance Training in Patients With Ischemic CMP June 29, 2022 December 12, 2023
NCT03549468 Completed N/A The Effect of Low LEVel TrAgus STimulation on the Electrophysiological Substrate of Patients With Ischemic CardioMyopathy Substrate of Subjects With Ischemic CardioMyopathy May 25, 2018 March 30, 2022
NCT03607669 Completed Manganese-Enhanced Magnetic Resonance Imaging of the Myocardium June 1, 2018 February 1, 2020
NCT03857906 Completed Evaluation of Prophylactic Use of a Preoperative IABP in High-Risk Coronary Artery Bypass Graft Surgery October 21, 2014 January 19, 2019
NCT06056687 Completed N/A Alpha-lipoic Acid in Diabetic Patients With Ischemic Cardiomyopathy March 1, 2023 February 1, 2024
NCT01753440 Completed Phase 2 Allogeneic Stem Cells Implantation Combined With Coronary Bypass Grafting in Patients With Ischemic Cardiomyopathy November 2012 December 2014
NCT00305214 Completed N/A MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients October 2003 February 2007
NCT01913886 Completed Phase 1/Phase 2 Mesenchymal Stem Cells to Treat Ischemic Cardiomyopathy January 2010 March 2016
NCT01919983 Completed Inflammation, Cardiac Sympathetic Innervation, and Arrhythmic Sudden Death March 2012 September 2014
NCT01920048 Completed N/A Study of Efficacy and Safety of Percutaneous Coronary Intervention to Improve Survival in Heart Failure August 28, 2013 March 31, 2022
NCT00305240 Completed N/A MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients October 2003 February 2007
NCT01989195 Completed Phase 1/Phase 2 Efficacy of EVP 1001-1 (SeeMore) in the Assessment of Myocardial Viability in Patients With Cardiovascular Disease May 2013 June 2013
NCT05508269 Completed Genetics of Ischemic Cardiomyopathy April 1, 2021 August 17, 2022
NCT02501811 Completed Phase 2 Combination of Mesenchymal and C-kit+ Cardiac Stem Cells as Regenerative Therapy for Heart Failure October 2015 July 22, 2020
NCT04508608 Completed Scintigraphic Evaluation of Contractile and Coronary Reserve in Patients With Ischemic Cardiomyopathy September 1, 2018 September 1, 2021
NCT00568542 Completed Phase 4 Chronic, Low Dose Erythropoetin Beta in Ischemic Cardiomyopathy May 2006 October 2008
NCT02933034 Completed Phase 1/Phase 2 Clinical Trial of Manganese-Enhanced MRI (MEMRI) to Assess Peri-Infarct Injury April 2015 February 3, 2019
NCT03022487 Completed Multicentre Investigation of Novel Electrocardiogram Risk Markers in Ventricular Arrhythmia Prediction July 8, 2016 September 30, 2022
NCT04190394 Completed Comparison of Two Exercise Training Modes on Left Myocardial Regional Function After Myocardial Infarction Evaluated by 2D Strain Ultrasound March 12, 2020 July 20, 2023
NCT03209843 Completed N/A Post-stenting Assessment of Reendothelialization With OFDI After CTO Procedure (PERFECTO) March 7, 2018 February 12, 2021
NCT03212326 Completed N/A Contrast ICE for Myocardial Scar in VT Ablations March 2013 December 2018
NCT03862339 Completed The SoundScar Study The SOUNDSCAR Study November 9, 2018 April 1, 2021
NCT03421834 Completed N/A Impact of PREVENTIVE Substrate Ablation of Coronary Chronic Total Occlusion on Implantable cardioVerTer-Defibrillator Interventions February 6, 2018 January 4, 2024
NCT00981006 Completed Phase 1 AutoLogous Human CArdiac-Derived Stem Cell to Treat Ischemic cArdiomyopathy (ALCADIA) April 2010 March 2013
NCT01215253 Completed Phase 3 Ranolazine Implantable Cardioverter-Defibrillator Trial September 2011 February 28, 2017
NCT01288560 Completed N/A IMAGE-HF Project I-A: Cardiac Imaging in Ischemic Heart Failure (AIMI-HF) January 2011 October 4, 2022
NCT00187291 Completed Phase 3 Study to Compare TWA Test and EPS Test for Predicting Patients at Risk for Life-threatening Heart Rhythms (ABCD Study) April 2001 July 2006
NCT01400334 Completed Prediction of ARrhythmic Events With Positron Emission Tomography July 2004 December 2012
NCT01474486 Completed N/A Feasibility and Effectiveness of Micronutrients as Palliative Care Therapy in Patients With Congestive Heart Failure April 2010 February 2016
NCT01557465 Completed Mechanical Alternans Study November 2009 April 2015
NCT01603706 Completed N/A Radial Strain ECHO-Guided Implantation of Cardiac Resynchronization Therapy May 2012 October 2017
NCT01643330 Completed Phase 2 A Study of Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure July 2012 February 2016
NCT00203203 Completed Phase 1 Autologous Stem Cells for Cardiac Angiogenesis (FOCUS HF) April 2004 November 2009
NCT05713357 Enrolling by invitation Repeated Endocardial Mapping for Efficacy Assessment After Catheter Ablation for Ischemic Ventricular Tachycardia March 15, 2023 July 1, 2026
NCT06138873 Not yet recruiting N/A Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy July 1, 2024 July 1, 2027
NCT05760924 Not yet recruiting N/A Left Bundle Branch Pacing on Outcomes and Ventricular Remodeling in Biventricular CRT Nonresponders May 1, 2024 September 1, 2028
NCT05674955 Not yet recruiting N/A CWT Versus AT on Selected Cardiovascular Indices and Functional Capacity in Patients With Ischemic Cardiomyopathy. February 8, 2024 March 8, 2024
NCT03531151 Recruiting MRI of Myocardial Infarction April 1, 2018 March 31, 2026
NCT03590925 Recruiting Evaluation of the Improvement of Primary Prevention in Ischemic Cardiomyopathy Patients Using New Screening and Referring System (Advance-ICM) March 21, 2018 June 30, 2024
NCT05828719 Recruiting N/A Revascularization Versus Medical Treatment in Patients With Ischemic Left Ventricular Dysfunction June 16, 2023 December 31, 2030
NCT05855135 Recruiting N/A Assessment of Combined CCM and ICD Device in HFrEF May 17, 2023 December 2025
NCT01999140 Recruiting Implantable Cardioverter Defibrillator (ICD Registry) June 2005 June 2030
NCT05632432 Recruiting N/A Atrial Appendage Micrograft Transplants to Assist Heart Repair After Cardiac Surgery April 1, 2024 December 31, 2026
NCT05511246 Recruiting Phase 2 Venous Ethanol for Ventricular Tachycardia April 12, 2023 December 12, 2028
NCT04339452 Recruiting Impella Supported OPCABG May 11, 2022 March 2025
NCT04852497 Recruiting SMART Identification of Ventricular Tachycardia Isthmus April 1, 2018 September 1, 2024
NCT05888662 Recruiting N/A Endo-epicardial vs Endocardial-only Catheter Ablation of Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy (EPIC-VT) October 23, 2023 October 23, 2028
NCT03536052 Recruiting N/A Ablation at Virtual-hEart pRedicted Targets for VT September 26, 2022 September 1, 2025
NCT05769036 Recruiting N/A Conventional Biventricular Versus Left Bundle Branch Pacing on Outcomes in Heart Failure Patients October 1, 2023 September 1, 2028
NCT01076660 Recruiting Left Ventricular Structural Predictors of Sudden Cardiac Death October 2003 June 2030
NCT03071653 Suspended Phase 2 Left Cardiac Sympathetic Denervation for Cardiomyopathy Feasibility Pilot Study November 24, 2016 February 2022
NCT02573207 Terminated Recovery of Hibernating Myocardium in End Stage Heart Failure March 2016 April 9, 2019
NCT01290822 Terminated Phase 1/Phase 2 Optimized Biventricular Pacing Allograft Recipients January 2007 March 2011
NCT01721902 Terminated Phase 1 Stem Cell Implantation in Patients Undergoing CABG January 2010 December 2013
NCT01759212 Terminated Phase 2/Phase 3 Left Ventricular Assist Device Combined With Allogeneic Mesenchymal Stem Cells Implantation in Patients With End-stage Heart Failure. October 2012 July 2022
NCT01966887 Terminated Phase 2 AAV1-CMV-Serca2a GENe Therapy Trial in Heart Failure December 2013 February 2016
NCT02346422 Terminated Phase 1/Phase 2 A Phase 1/2 Study of High-dose Genetically Targeted Enzyme Replacement Therapy for Advanced Heart Failure April 2015
NCT00102128 Terminated Phase 2 Study to Examine the Safety and Effectiveness of Implanted Skeletal Muscle Cells (Cells Removed From the Thigh Muscle) Into Scarred Areas of Heart Muscle After Heart Attack. November 2002 April 2007
NCT04066738 Terminated N/A Scar Location and Acute Haemodynamic Response to MultiPoint Pacing Study in Patients With Ischemic Cardiomyopathy September 27, 2017 March 30, 2020
NCT03830957 Unknown status N/A Efficacy and Safety of Ivabradine to Reduce Heart Rate Prior to Coronary CT-angiography in Advanced Heart Failure: Comparison With β-Blocker November 26, 2018 December 2019
NCT03244748 Unknown status Amiodarone Usage After Ischemic Ventricular Tachycardia Ablation January 1, 2016 March 1, 2018
NCT00955539 Unknown status N/A Viability and Cardiac Resynchronization Therapy August 2009 June 2013
NCT00626314 Unknown status Phase 2 Study to Assess the Efficacy and Safety of Transplanting Autologous Skeletal Myoblasts, Into Infarcted Heart, Using an Catheter Delivery System March 2008 August 2010
NCT03798652 Unknown status Improved Prediction of Functional Recovery After Revascularisation Using Combined Assessment of Myocardial Ischaemia and Viability by CMR - Pilot Study March 3, 2019 June 30, 2022
NCT04146701 Unknown status Metabolomics and Microbiomics in Cardiovascular Diseases February 1, 2019 December 31, 2022
NCT03147027 Unknown status Catheter Ablation for Nonsustained Ventricular Tachycardia in Patients With Ischemic Cardiomyopathy May 2, 2017 December 2020
NCT02930265 Unknown status N/A Clinical Study of Liraglutide in Improving Cardiac Function for Patients With Ischemic Cardiomyopathy September 2016 March 2018
NCT02666391 Unknown status Phase 1/Phase 2 Safety and Exploratory Efficacy Study of UCMSCs in Patients With Ischemic Heart Disease (SEESUPIHD) May 2016 December 2017
NCT02506166 Unknown status N/A European Sleep Apnea and Sudden CArdiac Death ProjEct January 2016 December 2022
NCT04588675 Unknown status Stress Cardiac MRI in Ischemic Patients November 2021 June 2022
NCT02504437 Unknown status Phase 1/Phase 2 Therapy of Preconditioned Autologous BMMSCs for Patients With Ischemic Heart Disease November 2015 December 2017
NCT02368587 Unknown status Phase 2 Intracoronary or Intravenous Infusion Human Wharton' Jelly-derived Mesenchymal Stem Cells in Patients With Ischemic Cardiomyopathy January 1, 2020 July 2021
NCT04897997 Unknown status Effect of Smoking on Activated Clotting Time Values During Coronarography and Angioplasty January 6, 2020 September 30, 2022
NCT05194865 Unknown status Coronary Revascularization Based on CMR Viability Study Vs Direct Revascularization in Ischemic Cardiomyopathy Patients February 1, 2022 July 2023
NCT02358746 Unknown status N/A Ventricular Tachycardia in Ischemic Cardiomyopathy; a Combined Endo-Epicardial Ablation Within the First Procedure Versus a Stepwise Approach May 2015 December 2019
NCT02293603 Unknown status Phase 1 Dilated cardiomYopathy iNtervention With Allogeneic MyocardIally-regenerative Cells (DYNAMIC) November 2014 April 2020
NCT02058771 Unknown status Utilising Lifemap to Investigate Malignant Arrhythmia Therapy October 2013 November 2022
NCT01946048 Unknown status Phase 1 Umbilical Cord Derived Mesenchymal Stem Cells Therapy in Ischemic Cardiomyopathy October 2013 December 2014
NCT01447069 Unknown status N/A Use of Beta-agonists in Stable Severe Congestive Heart Failure October 2011 March 2012
NCT01019226 Unknown status Implementation of Work in Progress (WIP) Sequences in Magnetic Resonance Imaging (MRI) December 2009 May 2011
NCT00972114 Unknown status Phase 1/Phase 2 CABG Combined Pedicled Omentum Wrapped Autologous Atrial Tissue Patch Cardiomyoplasty for Ischemic Cardiomyopathy October 2009 December 2011
NCT00962364 Unknown status Long-term Evaluation of Patients Receiving Bone Marrow-derived Cell Administration for Heart Disease October 2001 December 2021
NCT00326690 Withdrawn N/A Study Tests Whether a Standardized LVR Performed With the Blue Egg Device Improves Cardiopulmonary Exercise Capacity November 2005 December 2008
NCT01825239 Withdrawn N/A Virtual LV Lead Navigation in Patients With Ischemic Cardiomyopathy April 2014 October 2014
NCT01496209 Withdrawn Phase 1 REgenerative CardiOsphere iNjection to STRengthen dysfUnCTional Hearts July 2015 September 2017