Diabetic foot ulcer
Information
- Disease name
- Diabetic foot ulcer
- Disease ID
- Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03754465 | Active, not recruiting | Phase 2 | Clinical Study of ALLO-ASC-SHEET in Subjects With Diabetic Foot Ulcers | May 9, 2019 | May 2024 |
| NCT06213337 | Active, not recruiting | N/A | Virtual Classroom Training and SMS Supported Interventions Improving Foot Care and Self-Efficacy | March 1, 2023 | April 2024 |
| NCT05009602 | Active, not recruiting | Diagnostic Tools to Establish the Presence and Severity of Peripheral Arterial Disease in People With Diabetes | March 14, 2022 | February 28, 2024 | |
| NCT04828304 | Active, not recruiting | N/A | PLASOMA Ultimate Safety & Efficacy Study | May 26, 2021 | December 2024 |
| NCT04927702 | Active, not recruiting | N/A | Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU) | July 19, 2021 | August 1, 2024 |
| NCT04133493 | Active, not recruiting | N/A | Omega3 Wound Fish Skin Graft in the Treatment of DFUs | July 31, 2019 | January 30, 2023 |
| NCT05007301 | Active, not recruiting | Geko™ Cross Therapy Registry - Wound | April 4, 2022 | March 2028 | |
| NCT05687643 | Active, not recruiting | Shear Load In-shoe Plantar Sensing/Strain Analyses and Mapping in Diabetic Foot Ulcers | July 1, 2022 | April 3, 2024 | |
| NCT06003530 | Active, not recruiting | Phase 1 | Study for Treatment of Chronic Diabetic Foot Ulcers With the Investigational Allogeneic Cell Therapy Product, hOMSC200 | January 6, 2022 | December 31, 2024 |
| NCT06292026 | Active, not recruiting | N/A | Efficacy of ProgenaMatrix™ in the Management of DFUs | March 14, 2022 | September 2026 |
| NCT04939038 | Active, not recruiting | N/A | Timing of Revascularization in Patients With Diabetic Foot Ulcer and Non-critical Peripheral Artery Disease | January 25, 2022 | January 24, 2026 |
| NCT05165628 | Active, not recruiting | Phase 1 | Safety, Tolerability and Efficacy of CYP-006TK in Adults With Diabetic Foot Ulcers | January 4, 2022 | September 2024 |
| NCT06067022 | Completed | Temporomandibular Dysfunction in Patients With Diabetic Foot Ulcers | January 5, 2023 | July 5, 2023 | |
| NCT06000722 | Completed | SGLT-i Use in Diabetic Foot Ulcer Disease | December 5, 2023 | April 30, 2024 | |
| NCT00915486 | Completed | Phase 2 | A Dose Finding Study of Topically Applied I-020201 as an Adjunct to Good Standard-of-care in Patients With Chronic Diabetic Foot Ulcers | May 2009 | March 2012 |
| NCT00289497 | Completed | Phase 2/Phase 3 | TempTouch IR Thermometry & Diabetic Patient Self-Care | June 2000 | July 2003 |
| NCT00935051 | Completed | Early Phase 1 | Matrix Metalloproteinase-1/Tissue Inhibitor of Metalloproteinase-1 (MMP-1/TIMP-1) Ratio and Diabetic Foot Ulcers | May 2009 | November 2013 |
| NCT01108120 | Completed | Phase 2 | The Therapeutical Role of Continuous Intra-femoral Artery Infusion of Urokinase on Diabetic Foot Ulcers | May 2010 | December 30, 2022 |
| NCT01113515 | Completed | Phase 1/Phase 2 | Clinical Investigation of Galnobax® for the Treatment of Diabetic Foot Ulcers | February 20, 2014 | October 17, 2015 |
| NCT01181440 | Completed | Phase 3 | Dermagraft(R) for the Treatment of Patients With Diabetic Foot Ulcers | September 1994 | January 1997 |
| NCT01181453 | Completed | Phase 3 | Pivotal Trial of Dermagraft(R) to Treat Diabetic Foot Ulcers | December 1998 | March 2000 |
| NCT01389362 | Completed | Phase 2/Phase 3 | The Healing Effect of a Two-Herb Recipe on Foot Ulcer in Chinese Patients With Type 2 Diabetes | May 2009 | May 2011 |
| NCT01427569 | Completed | Phase 2 | Efficacy Study of IZN-6D4 Gel for the Treatment of Diabetic Foot Ulcers | March 2012 | August 2015 |
| NCT01450943 | Completed | Phase 3 | VA MERIT: A Comparative Efficacy Study: Treatment of Non-Healing Diabetic | October 1, 2011 | April 4, 2018 |
| NCT05797285 | Completed | N/A | Evaluating The Efficacy Of A Keratin Graft In Treating Non-Healing Diabetic Foot Ulcers | February 28, 2023 | December 20, 2023 |
| NCT01552499 | Completed | N/A | Comparative Study of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers | March 2012 | August 2012 |
| NCT05786612 | Completed | N/A | A Clinical Investigation Comparing the Clinical Performance and Cost Effectiveness of Biatain® Silicone Compared With SoC | January 30, 2023 | December 27, 2023 |
| NCT05729334 | Completed | N/A | Clinical Investigation EUCLIDES-01 for the Calculation of the Area of Skin Lesions | November 28, 2022 | March 21, 2023 |
| NCT01645891 | Completed | N/A | A Prospective, Randomized, Double-Blind Multicenter Study Comparing Continuous Diffusion of Oxygen (CDO) Therapy to Standard Moist Wound Therapy (MWT) in the Treatment of Diabetic Foot Ulcers | April 2012 | November 2016 |
| NCT01657474 | Completed | N/A | Comparative Study of Two Application Regimens of Amniotic Membrane Wound Graft In the Management of Diabetic Foot Ulcers | September 2012 | November 2013 |
| NCT01676272 | Completed | Multi Center Site , Controlled Trial Comparing a Bioengineered Skin Substitute to a Human Skin Allograft | July 2012 | November 2015 | |
| NCT01693133 | Completed | N/A | Trial of Dehydrated Human Amnion/Chorion Membrane (dHACM) In the Management of Diabetic Foot Ulcers | July 2012 | June 2018 |
| NCT01731808 | Completed | N/A | Outpatient Nurse Managed Counseling Program for Patients With Diabetic Foot Ulceration: a Pilot Study | October 2010 | March 2013 |
| NCT01813305 | Completed | Phase 2 | CSTC1 for Diabetic Foot Ulcers Phase II Study | July 9, 2014 | January 7, 2020 |
| NCT01814267 | Completed | Phase 2/Phase 3 | Medico-economical Assessment of Telemedicine During Chronic Diabetes-related Foot Wound Management | March 2013 | June 2015 |
| NCT05687656 | Completed | N/A | Sterilised, Porcine Placental Tissue in the Treatment of Chronic Diabetic Foot Ulcers | October 6, 2022 | January 31, 2024 |
| NCT01835379 | Completed | Phase 4 | Study of Oasis Ultra in Diabetic Foot Ulcers | May 2013 | September 2014 |
| NCT01844479 | Completed | N/A | Multi-layer Insoles for a Patient-specific Approach to Shear and Pressure Reduction in Diabetes-related Foot Ulcer | December 2012 | January 2014 |
| NCT01921491 | Completed | N/A | DHACM vs Other Commercially Available Treatments | August 2013 | September 2015 |
| NCT01951768 | Completed | Phase 4 | Efficacy and Safety of Garamycin® Sponge in Diabetic Patients With a Moderate or Severe Foot Ulcer Infection | September 2013 | June 2016 |
| NCT05671250 | Completed | Phase 2 | Bioactive Smart Dressings for Diabetic Foot Ulcers: Randomized Controlled Trial | July 15, 2021 | January 1, 2023 |
| NCT01970163 | Completed | N/A | DermACELL in Subjects With Chronic Wounds of the Lower Extremities | October 2013 | April 2016 |
| NCT01982565 | Completed | Phase 1/Phase 2 | Nitric Oxide Generating Gel Dressing in Patients With Diabetic Foot Ulcers | June 2013 | December 2015 |
| NCT02019082 | Completed | N/A | Electrical Stimulation and Expression of VEGF and NO in Diabetic Foot Ulcer | March 2011 | December 2011 |
| NCT02070835 | Completed | N/A | Study of Autologous Skin Cell Treating for Diabetic Foot Ulcers | April 2014 | December 2022 |
| NCT05619237 | Completed | N/A | Pivotal Study of an Antimicrobial Wound Dressing to Treat Chronic Wounds | December 6, 2022 | May 30, 2023 |
| NCT05551988 | Completed | Predictors of Foot Amputation in Diabetic Foot Ulcers | June 1, 2021 | June 30, 2022 | |
| NCT02091596 | Completed | Phase 2 | Topical PluroGel N for the Treatment of Mildly Infected Diabetic Foot Ulcers | October 2013 | September 2014 |
| NCT02119754 | Completed | Phase 2 | Topical PluroGel PN for the Treatment of Mildly Infected Diabetic Foot Ulcers | October 2013 | September 2014 |
| NCT05422846 | Completed | N/A | Investigation of the Effects of Different Exercise on Wound Healing in Patients wıth Diabetic Foot Wounds | August 1, 2022 | July 1, 2023 |
| NCT05324930 | Completed | N/A | Evaluating the Effectiveness of Piscean Derived Collagen Dressing on Neuropathic Diabetic Foot Ulcer in T2DM Patients | December 2, 2021 | September 1, 2022 |
| NCT05243810 | Completed | N/A | EPC Silver Wound Gel (EPC-123) Feasibility Study in the Management of Mildly Infected Diabetic Foot Ulcers | November 28, 2022 | September 21, 2023 |
| NCT02224742 | Completed | Phase 4 | LeucoPatch in the Management of Hard-to-heal Diabetic Foot Ulcers | August 2013 | May 2018 |
| NCT02236793 | Completed | Phase 3 | A Phase 3 Clinical Trial to Assess the Effectiveness of BioChaperone PDGF-BB In the Treatment of Chronic Diabetic Foot Ulcer | December 2014 | August 2016 |
| NCT02251418 | Completed | N/A | Shockwave Therapy of Chronic Diabetic Foot Ulcers | February 2015 | December 2015 |
| NCT05215730 | Completed | N/A | Comparison of Wound Healing Between MedCu Dressings With Copper Oxide and Negative Pressure Wound Therapy Treatment | July 7, 2021 | October 10, 2023 |
| NCT02328508 | Completed | Phase 1 | Hyperbaric Oxygen Therapy in Diabetics With Chronic Foot Ulcers and Improvement of Quality of Life | June 2011 | June 2013 |
| NCT02329366 | Completed | Development of a Cellular Biomarker for the Diagnosis and Treatment of Diabetic Foot Ulcers | December 2014 | December 1, 2020 | |
| NCT02361931 | Completed | Phase 1/Phase 2 | Topical Erythropoietin Hydrogel Formulation for Diabetic Foot Ulcers | March 21, 2016 | June 12, 2018 |
| NCT02379468 | Completed | Phase 3 | Efficacy & Safety of Pedyphar Ointment in Diabetic Foot Ulcer Treatment | April 2013 | October 2014 |
| NCT02394886 | Completed | Phase 1 | Safety of ALLO-ASC-DFU in the Patients With Diabetic Foot Ulcers | November 2014 | July 2015 |
| NCT02405767 | Completed | N/A | BioimPEDance of Diabetic Foot Ulcers | April 2015 | September 2, 2016 |
| NCT05148390 | Completed | Study to Examine Clinical Performance and Safety of Cutimed® Gelling Fiber in Routine Clinical Practice | April 24, 2022 | July 26, 2023 | |
| NCT02440282 | Completed | Comparison of Anesthetic Modalities on Hemodynamic Stability and Postoperative Pain in Diabetic Foot Patients Undergoing Minor Lower Extremity Amputation | January 2012 | December 2014 | |
| NCT02452086 | Completed | N/A | Low Level Laser Therapy and Expression of VEGF, NO, VEGFR-2, HIF-1α in Diabetic Foot Ulcers | June 2013 | February 2015 |
| NCT02581098 | Completed | miR-200b & miR-21 in Diabetic Wounds | August 2015 | June 26, 2023 | |
| NCT05145439 | Completed | N/A | A Non-significant Risk Clinical Study of Therapeutic Ultrasound for Patients With Diabetic Foot Ulcers. | January 14, 2023 | December 13, 2023 |
| NCT02619877 | Completed | Phase 2 | Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Foot Ulcers | October 2015 | October 2016 |
| NCT02632877 | Completed | Phase 1/Phase 2 | Efficacy of Pirfenidone Plus MODD in Diabetic Foot Ulcers | January 2014 | December 2015 |
| NCT02632929 | Completed | Prevention of Amputation in Diabetic Foot Ulcers Using Amniotic Tissue | May 30, 2015 | September 30, 2019 | |
| NCT02657876 | Completed | Phase 1 | ExpressGraft-C9T1 Skin Tissue as a Treatment of Diabetic Foot Ulcers | January 31, 2018 | May 28, 2019 |
| NCT02677779 | Completed | N/A | CO2-Laser Treatment in Patients With Diabetic Infected Foot Ulcers | January 2016 | March 2016 |
| NCT05101473 | Completed | N/A | Exercise Therapy for People With a Diabetic Foot Ulcer - a Feasibility Study | September 1, 2021 | April 1, 2022 |
| NCT02783066 | Completed | Phase 2 | Novel Offloading for Diabetic Foot Ulcers With PulseFlow: A Prospective Study | January 2016 | October 30, 2019 |
| NCT02799121 | Completed | Phase 4 | A Feasibility Study of the ReGenerCell™ Autologous Cell Harvesting Device for Diabetic Foot Ulcers | May 2016 | March 29, 2019 |
| NCT06464250 | Completed | N/A | The Effect of Bundle Approach on Foot Care Behaviors and Diabetic Wound Healing in Patients | September 1, 2023 | February 29, 2024 |
| NCT02870816 | Completed | N/A | Prospective, Comparitive, Randomized Study of Allograft Versus Skin Substitute in Non-healing Diabetic Foot Ulcers | August 31, 2016 | June 14, 2018 |
| NCT02967900 | Completed | Longitudinal Study of Chronic Wounds Using Novel Wound Measurement Technologies | October 1, 2017 | March 1, 2018 | |
| NCT05071235 | Completed | N/A | Quality of Life and Self-care in Patients With Diabetic Foot Ulcers Treated With Low-level Laser Therapy | August 27, 2019 | November 30, 2022 |
| NCT05039645 | Completed | N/A | Use of Remote Thermovisual Monitoring in Patients With a Previous Diabetic Foot Ulcer | March 31, 2022 | December 12, 2023 |
| NCT02994966 | Completed | N/A | Diabetes Foot Care Clinical Pathway - Orpyx Medical Technologies | November 2016 | February 26, 2020 |
| NCT02995863 | Completed | N/A | This Research Hypothesizes That the Use of a Rigid Rocker Sole Reduces the Recurrence Rate of Diabetic Foot Ulcers in Patients With Peripheral Neuropathy. | December 10, 2016 | May 10, 2018 |
| NCT03002155 | Completed | N/A | Effects of a Exercise Program on Health Outcomes in People With Diabetic Foot Ulcers | January 2017 | June 2018 |
| NCT03010319 | Completed | N/A | PriMatrix for the Management of Diabetic Foot Ulcers | January 2017 | August 2020 |
| NCT03021811 | Completed | N/A | EUREKA Italy - Evaluation of Real-life Use of KLOX BioPhotonic System in Chronic Wounds Management | October 2015 | April 2017 |
| NCT04959071 | Completed | N/A | Mean Healing Time of Wound After Vacuum Assisted Closure (VAC) Versus Conventional Dressing in Diabetic Foot Ulcer Patients | February 28, 2020 | August 27, 2020 |
| NCT03044132 | Completed | N/A | DermACELL AWM® in Chronic Wagner Grade 3/4 Diabetic Foot Ulcers | January 15, 2017 | December 31, 2018 |
| NCT03063138 | Completed | Evaluation of 3D Imaging Ulcer Camera | August 1, 2015 | March 1, 2017 | |
| NCT04058626 | Completed | TEsting for Arterial Disease in Diabetes (TrEAD) Study | March 4, 2019 | October 18, 2019 | |
| NCT04104451 | Completed | Phase 1 | PHASE 1, OPEN-LABEL SAFETY STUDY OF UMBILICAL CORD LINING MESENCHYMAL STEM CELLS (CORLICYTE®) TO HEAL CHRONIC DIABETIC FOOT ULCERS | November 12, 2019 | August 1, 2023 |
| NCT06373809 | Completed | Early Phase 1 | Placenta Derived Stem Cells for Treating of Chronic Ulcers and Neuropathy | October 8, 2021 | March 31, 2024 |
| NCT00393510 | Completed | Phase 2 | Herbal Preparation Used as Adjuvant Therapy on Diabetic Ulcers | November 2000 | March 2006 |
| NCT00477022 | Completed | N/A | The Effects of Vacuum-Compression Therapy on the Healing of Diabetic Foot Ulcers | February 2006 | November 2006 |
| NCT00593567 | Completed | Phase 2 | Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With a Mild Infection of a Foot Ulcer | December 2007 | May 2009 |
| NCT06160817 | Completed | N/A | Ulcer Location and Debridement Frequency: Weekly vs. Biweekly Sharp Debridement in Diabetic Foot Ulcers | January 11, 2024 | May 6, 2024 |
| NCT00659646 | Completed | Phase 2 | The Safety and Efficacy of an Antibiotic Sponge in Diabetic Patients With Moderately Infected Foot Ulcers | April 2008 | February 2010 |
| NCT00662831 | Completed | Phase 2/Phase 3 | Study Of The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients | April 2008 | October 2010 |
| NCT00719251 | Completed | N/A | Effects of High Voltage Pulsed Current (HVPC) and Low Level Laser Therapy (LLLT) on Wound Healing in Diabetic Ulcers | March 2004 | December 2006 |
| NCT00764361 | Completed | Phase 2 | Safety Study of Topical Doxycycline Gel for Adult Diabetic Lower Extremity Ulcers | January 2009 | August 2010 |
| NCT00765063 | Completed | Phase 2/Phase 3 | The Effect Of Fragmin In The Treatment Of Neuroischaemic Foot Ulcers In Diabetic Patients (A6301086) | October 2008 | October 2010 |
| NCT04025853 | Completed | Inflammatory Biomarkers to Diagnose and Monitor Diabetic Foot Osteomyelitis | June 2015 | March 2018 | |
| NCT04054804 | Completed | Digital Foot Check by Using the D-Foot, a New Software | September 16, 2019 | December 31, 2019 | |
| NCT04055064 | Completed | N/A | The Effects of Nutrition Supplementation and Education on the Healing of Diabetic Foot Ulcer (DFU) | May 23, 2017 | May 9, 2018 |
| NCT04154020 | Completed | N/A | Treatment of Ulcers Associated With Hammer, Mallet and Claw Toe Deformities in the Diabetic Patient Setting | November 30, 2019 | October 28, 2021 |
| NCT03135964 | Completed | N/A | The Study of Wound Dressings for Portable NPWT | February 2011 | March 2016 |
| NCT03136822 | Completed | N/A | DERMALIX Efficacy on Diabetic Foot Ulcers | April 26, 2017 | August 1, 2018 |
| NCT00338923 | Completed | Phase 1 | Wound Healing Effects of HO/03/03 In Patients With Diabetic Neuropathic Plantar and Venous Ulcers, Pilot Study. | June 2006 | May 2007 |
| NCT03146845 | Completed | N/A | Evaluation Of An Advanced Borderless Dressing | June 15, 2017 | June 18, 2018 |
| NCT04918784 | Completed | N/A | Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers | May 5, 2021 | December 1, 2022 |
| NCT03182582 | Completed | N/A | Efficacy of Laser Debridement on Pain and Bacterial Load in Chronic Wounds | January 5, 2017 | March 17, 2017 |
| NCT03183726 | Completed | A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-101 Clinical Trial | January 11, 2016 | July 31, 2017 | |
| NCT03183804 | Completed | A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-201 Clinical Trial | December 29, 2015 | October 24, 2018 | |
| NCT03205436 | Completed | N/A | Affinity Prospective Diabetic Foot Trial Crossover Group | May 1, 2017 | August 15, 2019 |
| NCT04817228 | Completed | Phase 2 | A Study to Evaluate the Clinical Performance, Safety and Pharmacology Effect of EscharEx in Patients With Lower Leg Ulcers | April 21, 2021 | May 20, 2022 |
| NCT03232333 | Completed | MIRODERM H2H DFU Study | July 21, 2017 | September 20, 2018 | |
| NCT04803708 | Completed | Phase 1/Phase 2 | Bacteriophage Therapy TP-102 in Diabetic Foot Ulcers | March 22, 2021 | September 5, 2022 |
| NCT04769115 | Completed | N/A | A Predictive Technology for Prevention of Diabetic Foot Ulcers | February 24, 2021 | July 1, 2021 |
| NCT03312595 | Completed | N/A | Clinical Outcomes After Treatment With RestrataTM Wound Matrix in Diabetic Foot Ulcers (DFU) | September 14, 2017 | July 30, 2018 |
| NCT03341559 | Completed | Spatial Frequency Domain Imaging (SFD) for Assessment of Diabetic Foot Ulcer Development and Healing | March 20, 2018 | February 13, 2020 | |
| NCT03370874 | Completed | Phase 3 | Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Foot Ulcers. | June 27, 2018 | February 20, 2020 |
| NCT03398538 | Completed | N/A | Resorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers | December 26, 2017 | October 31, 2018 |
| NCT04755647 | Completed | Phase 1/Phase 2 | Nitric Oxide Footbath for Treatment of Diabetic Foot Ulcers | February 23, 2021 | May 20, 2023 |
| NCT04753294 | Completed | N/A | Confirm Safety and Performance of Avance Solo and Avance Solo Adapt NPWT Systems | June 14, 2021 | July 21, 2023 |
| NCT04698720 | Completed | N/A | Contribution of Psychological Factors in the Healing of the Diabetic Foot Ulcer | February 1, 2019 | July 25, 2022 |
| NCT03476876 | Completed | Phase 2/Phase 3 | Comparative Effectiveness of Two Acellular Matrices (Dermacell vs. Integra) for Management of Deep Diabetic Foot Ulcers | April 2, 2018 | April 2, 2021 |
| NCT03503370 | Completed | Phase 2 | Preventing Diabetic Foot Ulcers Through Cleaner Feet | January 2, 2019 | January 6, 2023 |
| NCT04652999 | Completed | N/A | Relaxation Intervention in Patients With Diabetic Foot Ulcer | March 19, 2019 | November 30, 2021 |
| NCT03547635 | Completed | N/A | AMNIOEXCEL® Plus vs A Marketed Comparator vs SOC in the Management of Diabetic Foot Ulcers | May 3, 2018 | February 26, 2019 |
| NCT03583593 | Completed | Phase 2 | Evaluation of DIAMEL® Combined With Insulin in Diabetic Foot Ulcer | May 23, 2014 | November 30, 2017 |
| NCT03615755 | Completed | N/A | Short Duration Hyperbaric Oxygen Therapy to Improve HbA1c, Leukocyte, and Serum Creatinine | December 27, 2016 | March 31, 2017 |
| NCT03624023 | Completed | Phase 1/Phase 2 | TWB-103 for Treating Lower Limb Ulcers on Patients With DM | December 19, 2019 | July 9, 2021 |
| NCT04633642 | Completed | N/A | Ultrasound Assisted Wound Debridement (UAW) Versus Standard Wound Treatment in Complicated Diabetic Foot Ulcers (DFU) | November 1, 2017 | December 31, 2019 |
| NCT04624516 | Completed | N/A | Effect of Self-foot Exercise on the Incidence of Plantar Foot Diabetic Ulcer Recurrence | September 4, 2019 | July 30, 2020 |
| NCT03662997 | Completed | N/A | Clinical Study to Compare 3 Multi-Layered Foam Dressings for the Management of Chronic Wounds | March 19, 2019 | November 15, 2019 |
| NCT03670225 | Completed | N/A | Evaluating Clinical Acceptance of a NPWT Wound Care System | October 16, 2018 | January 30, 2020 |
| NCT04593693 | Completed | N/A | A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System | December 10, 2020 | May 18, 2021 |
| NCT04590703 | Completed | A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-301 Clinical Trial | June 24, 2020 | June 2, 2023 | |
| NCT04577183 | Completed | N/A | A Prospective, Open Label, Multicenter Trial for Evaluating the Efficacy of Treating and Managing Wounds in Elderly Population in Specialized Nursing Facilities Using RD1 | July 11, 2018 | February 1, 2019 |
| NCT03716141 | Completed | N/A | Autologous Platelets Rich Plasma (APRP) Treatment Vs Saline Dressing for the Management of Diabetic Foot Ulcer | January 1, 2018 | August 30, 2018 |
| NCT03717233 | Completed | N/A | Assistive ExoSkeletons to Enable Wearable Rehabilitation Robotics | October 18, 2018 | October 17, 2019 |
| NCT04558775 | Completed | TEWL Biomarker Study for Diabetic Foot Ulcer Recurrence | June 17, 2020 | December 30, 2022 | |
| NCT04537520 | Completed | N/A | Interventional Clinical Trial Comparing Kerecis Omega3 Wound Versus SOC in Diabetic Foot Wounds | July 2, 2020 | December 16, 2022 |
| NCT03742440 | Completed | Phase 4 | GrafixPL PRIME Evaluation Case Study | November 20, 2018 | March 1, 2020 |
| NCT04467606 | Completed | N/A | Motivational Interview Based Discharge Planning for Patients With Diabetic Foot Ulcers | August 1, 2020 | November 30, 2022 |
| NCT03788642 | Completed | N/A | Low-level Laser Therapy for the Treatment of Diabetic Foot Ulcer | January 15, 2019 | October 31, 2021 |
| NCT03821675 | Completed | N/A | Electrical Stimulation to Accelerate Wound Healing | February 28, 2019 | October 8, 2021 |
| NCT04440839 | Completed | N/A | Implementation of Telemedicine for Patient With Lower Extremity Wounds | March 1, 2020 | December 31, 2023 |
| NCT04395521 | Completed | N/A | The Feasibility of a Facebook Group-based Program for Foot Self-management Support of Adults With Diabetes in Canada | February 16, 2021 | October 30, 2021 |
| NCT04336176 | Completed | N/A | Evaluating Plantar Foot Pressure in a Novel Diabetic Offloading Device | March 22, 2018 | July 29, 2018 |
| NCT03863054 | Completed | An Observational Clinical Trial Examining the Effect of Topical Oxygen Therapy (NATROX™) on the Rates of Healing of Chronic Diabetic Foot Ulcers | August 17, 2018 | May 31, 2021 | |
| NCT03865394 | Completed | Phase 1/Phase 2 | Treatment of Chronic Wounds in Diabetic Foot Syndrome With Allogeneic Adipose Derived Mesenchymal Stem Cells | July 1, 2019 | September 30, 2021 |
| NCT03881254 | Completed | N/A | SkinTE™ in the Treatment of Diabetic Foot Wounds | April 2, 2019 | July 28, 2021 |
| NCT03888053 | Completed | Phase 1 | BB-101 for Treatment of Diabetic Lower Leg and Foot Ulcers | March 28, 2018 | December 31, 2023 |
| NCT04300205 | Completed | N/A | High Intensity LED Photobiomodulation Therapy for Chronic Leg and Foot Ulcers | February 25, 2020 | June 25, 2022 |
| NCT03905863 | Completed | N/A | The Effect of Natrox® Oxygen Wound Therapy on the Healing Rate of Chronic Diabetic Foot Ulcers | June 4, 2019 | October 18, 2020 |
| NCT04281992 | Completed | Phase 1/Phase 2 | Treatment of Diabetic Foot Ulcers With AUP1602-C | January 28, 2020 | March 20, 2023 |
| NCT03939000 | Completed | Clinical Profile and Laboratory Finding of DFU From Tertiary Hospitals in Bali | March 2016 | January 2019 | |
| NCT03955289 | Completed | Treatment of Foot and Leg Ulcers Using a Laser | January 15, 2019 | February 1, 2019 | |
| NCT04257370 | Completed | N/A | Kerecis Omega3 Wound Plus SOC vs. SOC Alone in Treating Severe Diabetic Foot Ulcers and Forefoot Amputations | July 9, 2020 | November 25, 2022 |
| NCT03978715 | Completed | The Effect of Implementing a Limb Loss Prevention Program on Amputation Rates | April 14, 2021 | October 7, 2022 | |
| NCT03985306 | Completed | N/A | Treatment of Diabetic Foot Ulcers With Inforatio Technique to Promote Wound Healing | March 20, 2019 | September 26, 2019 |
| NCT04246814 | Completed | N/A | Use of Low-level Laser Therapy in the Treatment of Diabetic Foot Ulcers | August 27, 2019 | August 18, 2023 |
| NCT04233580 | Completed | N/A | Characterization of AmnioExcel Plus in Two Treatment Paradigms | July 9, 2020 | April 6, 2021 |
| NCT03998436 | Completed | Phase 3 | Phase 3 Study to Evaluate the Safety and Efficacy of Galnobax® in Treating Diabetic Foot Ulcers | December 26, 2018 | December 6, 2021 |
| NCT05804890 | Enrolling by invitation | Comparing Activated Carbon Cloth Dressing and Silver-Based Dressing in a Diabetic Foot Ulcer Population | August 1, 2022 | July 31, 2023 | |
| NCT05888259 | Enrolling by invitation | N/A | Plantar Pressure Distribution in Diabetic Foot Ulcer | September 17, 2021 | July 20, 2023 |
| NCT06395961 | Enrolling by invitation | N/A | Effect of New High Ankle Block on Wound Healing After the Operation of Debridement of Diabetes Foot | August 2, 2023 | June 15, 2024 |
| NCT01238276 | No longer available | Direct Antibiotic Delivery of Cefazolin Into Soft Tissue Infections Using Subcutaneous Injection and Ultrasonic Dispersion | |||
| NCT05968924 | Not yet recruiting | N/A | Improving DFU Outcomes: Early Detection of Foot Ulcers Using Novel Technology | May 2024 | March 2025 |
| NCT02866565 | Not yet recruiting | Phase 2 | Assessment of the Efficacy and Tolerance of Sub-cutaneous Re-injection of Autologous Adipose-derived REGEnerative Cells in the Local Treatment of Neuropathic Diabetic Foot ulcERs | June 2023 | December 2026 |
| NCT03137966 | Not yet recruiting | Phase 2 | Effect of Deferoxamine on Wound Healing Rate in Patients With Diabetes Foot Ulcers | December 30, 2022 | June 30, 2026 |
| NCT04275804 | Not yet recruiting | N/A | Vibration Enhances Diabetic ULCER Healing | January 1, 2022 | December 31, 2024 |
| NCT04796649 | Not yet recruiting | N/A | Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers (LLL&DIAB-03) | May 15, 2022 | December 15, 2024 |
| NCT05072353 | Not yet recruiting | N/A | Effectiveness of the Autologous Adipose Tissue Harvested With SEFFICARE Method for Treatment of DFU Minor Amputation | December 2021 | October 2024 |
| NCT05095389 | Not yet recruiting | Phase 3 | Adipose Derived Regenerative Cells In the Treatment of Diabetic Foot Ulcers | February 28, 2023 | July 2025 |
| NCT05251480 | Not yet recruiting | N/A | Examining the Effectiveness of DermGEN™ in the Treatment of Diabetic Foot Ulcers in First Nations People | December 30, 2022 | December 1, 2025 |
| NCT05581966 | Not yet recruiting | Wound Assessment Using Spectral Imaging EU/UK | March 15, 2023 | July 30, 2023 | |
| NCT05704075 | Not yet recruiting | N/A | Clinical and Mechanistic Study of Transverse Tibial Transport in Complex Foot Ulcers | December 1, 2023 | January 31, 2026 |
| NCT05762432 | Not yet recruiting | N/A | Diabetic Foot Ulcer Research Study | February 26, 2024 | August 1, 2024 |
| NCT05843929 | Not yet recruiting | N/A | Prevalence of the Appearance of Diabetic Ulcers in Patients With 3D Insole and LSCI. | February 1, 2024 | April 1, 2025 |
| NCT05877378 | Not yet recruiting | N/A | Efficacy of PICO Single-use System in Chronic Ulcers | September 15, 2023 | April 1, 2024 |
| NCT05950659 | Not yet recruiting | N/A | WIREDUP: Wearable Insoles for Recurrent Diabetic Ulcer Prevention | January 1, 2024 | June 1, 2027 |
| NCT05977309 | Not yet recruiting | N/A | Effect of Topical Ozone on The Healing Diabetic Foot Ulcer | August 1, 2023 | August 30, 2023 |
| NCT06137222 | Not yet recruiting | N/A | Prospective, Multicenter, RCT of the Tenex Ultrasound System | December 4, 2023 | December 4, 2025 |
| NCT06150209 | Not yet recruiting | N/A | A Controlled Prospective Treatment Study to Evaluate the Efficacy of Vendaje. | January 15, 2024 | June 15, 2025 |
| NCT06227520 | Not yet recruiting | N/A | Acellular Dermal Allograft for Chronic Diabetic Wounds | April 1, 2024 | December 30, 2026 |
| NCT06231771 | Not yet recruiting | Phase 1/Phase 2 | Safety and Efficacy of Stem Cells for Diabetic Foot Ulcer | May 2024 | December 30, 2024 |
| NCT06278935 | Not yet recruiting | N/A | Lifestyle Tailored Offloading for Diabetic Foot Ulcers | April 2024 | April 2026 |
| NCT06312579 | Not yet recruiting | Phase 2 | At-Home Exercise Study for Veterans With Healed Diabetic Foot Ulcers | October 1, 2024 | March 31, 2026 |
| NCT06384183 | Not yet recruiting | Kerecis Real World Registry | July 2024 | June 2027 | |
| NCT06402565 | Not yet recruiting | Phase 1 | NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers | May 15, 2024 | June 30, 2025 |
| NCT06416462 | Not yet recruiting | N/A | Action of Photodynamic Therapy on Wound Quality and Tissue Repair in the Diabetic Foot | July 30, 2024 | December 30, 2024 |
| NCT06420245 | Not yet recruiting | N/A | Clinical Utility of an Amniotic Membrane Allograft for Diabetic Foot Ulcer Wound Management | June 2024 | July 2025 |
| NCT06437028 | Not yet recruiting | N/A | Evaluating the Efficacy of Perinatal Membrane Allografts for the Treatment of Diabetic Foot Ulcers. | September 2024 | September 2026 |
| NCT06439667 | Not yet recruiting | VIRTUALLY SUPERVISED TELE-EXERCISE PLATFORM FOR ACCELERATING PLANTAR WOUND HEALING | September 3, 2024 | January 3, 2028 | |
| NCT06444906 | Not yet recruiting | N/A | A Two-Part, Randomized Study of Dermacyte® Amniotic Wound Care Matrix | September 1, 2024 | May 31, 2025 |
| NCT06453187 | Not yet recruiting | N/A | A Modified Platform Trial of Multiple CAMPs for the Management of Diabetic Foot Ulcers and Venous Leg Ulcers | June 30, 2024 | August 31, 2026 |
| NCT06455475 | Not yet recruiting | N/A | Derm-Maxx in Patients With Diabetic Foot Ulcers Unresponsive to Standard of Care Treatment Alone | June 2024 | September 2025 |
| NCT06383013 | Recruiting | Phase 2 | Phase II Study of BB-101 for the Treatment of Diabetic Lower Leg and Foot Ulcers | February 29, 2024 | December 31, 2028 |
| NCT05189470 | Recruiting | N/A | Inforatio Technique to Promote Wound Healing of Diabetic Foot Ulcers | March 10, 2022 | February 2025 |
| NCT05193929 | Recruiting | N/A | A Clinical Investigation Evaluating Wound Closure With OptiPulse™ Versus SOC in the Treatment of Non-Healing DFU's | December 15, 2021 | December 15, 2024 |
| NCT05579743 | Recruiting | N/A | Feasibility and Effectiveness of a Remote Monitoring Program for the Treatment of Diabetic Foot Ulcers | January 6, 2023 | June 30, 2025 |
| NCT05236660 | Recruiting | N/A | Personalised Assistive Devices Approach for Diabetic Foot Ulcer Prevention | March 2, 2022 | July 2025 |
| NCT05570877 | Recruiting | N/A | ChitoCare Medical Wound Healing Gel PMCF Study on Healing of Chronic Wounds | January 11, 2022 | June 2023 |
| NCT04164641 | Recruiting | N/A | Noraxon myoRESEARCH™ Software Gait Analysis Evaluation and Orthotic Gait Correction in Reducing Diabetic Foot Ulceration Or Subsequent Amputation in Patients With a History of a Diabetic Foot Ulceration | December 9, 2019 | June 30, 2025 |
| NCT05519501 | Recruiting | N/A | Multi-Center, Randomized Controlled Clinical Investigation Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System in the Healing of Diabetic Foot Ulcers | October 10, 2021 | December 2025 |
| NCT04564443 | Recruiting | N/A | A Unique Micro Water Jet Technology Device Versus Standard Debridement in the Treatment of Diabetic Foot | September 11, 2020 | March 2024 |
| NCT05316298 | Recruiting | Diabetic Foot Osteomyelitis Treatment Using Gentamicin-loaded Calcium Sulfate-hydroxyapatite Biocomposite | December 1, 2022 | January 1, 2025 | |
| NCT04058639 | Recruiting | N/A | Diabetic Foot Ulcers: Shorter Treatment Period Using Custom Felt Relief? | October 1, 2019 | June 1, 2024 |
| NCT05464524 | Recruiting | Environmental Factors on DFUs Incidence - a Mixed-mode Survey | October 19, 2023 | January 30, 2025 | |
| NCT05415683 | Recruiting | Wound Assessment Using Spectral Imaging US | June 22, 2022 | June 2024 | |
| NCT04569409 | Recruiting | Phase 3 | Clinical Study to Evaluate Efficacy and Safety of ALLO-ASC-DFU in Patients With Diabetic Wagner Grade 2 Foot Ulcers. | July 14, 2020 | September 30, 2024 |
| NCT06319287 | Recruiting | Phase 2 | Phase 2a Multi-Center Prospective, Randomized Trial to Evaluate the Safety & Efficacy of Topical PEP-TISSEEL for Diabetic Foot Ulcers (DFU) | February 27, 2024 | July 12, 2025 |
| NCT06135987 | Recruiting | Clinical Evaluation in Real Life of TLC-NOSF Dressings in the Local Treatment of Chronic Wounds (DFU and VLU) | June 24, 2022 | October 2024 | |
| NCT04591691 | Recruiting | C-myc Biomarker Study for Diabetic Foot Ulcers | October 14, 2020 | December 31, 2023 | |
| NCT06111183 | Recruiting | Phase 2 | Evaluation of AUP12602-C as New Topical Treatment for DFUs (DIAMEND STUDY) | July 21, 2023 | October 31, 2025 |
| NCT04614038 | Recruiting | DETEC® pH Point of Care Wound Diagnostic Test | January 1, 2022 | December 31, 2024 | |
| NCT04614870 | Recruiting | DETEC® Esterase for Screening Wound Infection at Point of Care | May 1, 2022 | December 31, 2024 | |
| NCT04328181 | Recruiting | N/A | Comparison of Imaging Quality Between Spectral Photon Counting Computed Tomography (SPCCT) and Dual Energy Computed Tomography (DECT) | January 29, 2021 | January 29, 2026 |
| NCT06141811 | Recruiting | A Follow-up Study to Evaluate the Safety of ALLO-ASC-DFU in ALLO-ASC-DFU-302 Clinical Trial | April 25, 2023 | March 31, 2026 | |
| NCT03960255 | Recruiting | Effect of Adiposity and Associated Local Microbial Factors on Healing and Progression of Diabetic Foot Ulcers | February 20, 2021 | May 20, 2023 | |
| NCT04460573 | Recruiting | Phase 2 | Smart Boot Use to Measure Offloading Adherence | October 19, 2021 | December 2025 |
| NCT04689425 | Recruiting | Phase 3 | Umbilical Cord Blood Mononuclear Cell Gel in the Treatment of Refractory Diabetic Foot Ulcer | March 30, 2021 | December 31, 2024 |
| NCT06104969 | Recruiting | DFC 004 Biomarkers for Active Diabetic Foot Ulcers | June 15, 2023 | June 15, 2028 | |
| NCT05588583 | Recruiting | N/A | A Clinical Investigation to Follow the Progress of Exuding Chronic Wounds Using Mepilex® Up as the Primary Dressing. | October 31, 2022 | March 2024 |
| NCT05170984 | Recruiting | N/A | MAtrix Therapy for Hard-to-heal ChrOnic Wounds | February 10, 2022 | July 2024 |
| NCT06037369 | Recruiting | N/A | The Short Message-based Customized Standardized | September 14, 2023 | July 30, 2026 |
| NCT04723134 | Recruiting | Phase 2 | Evaluation of a Folic Acid Wound Treatment (FAWT) for Chronic, Early-Stage Diabetic Foot Ulcer (DFU) Healing | December 1, 2021 | July 2024 |
| NCT06035536 | Recruiting | N/A | Clinical Study Evaluating Symphony™ Versus Standard of Care in the Treatment of Non-Healing Diabetic Foot Ulcers | June 8, 2023 | December 27, 2024 |
| NCT03404895 | Recruiting | N/A | The Mount Sinai Diabetic Foot Ulcer Prospective Trial | April 13, 2018 | December 2024 |
| NCT06028386 | Recruiting | N/A | Use of AC5® Advanced Wound System in the Treatment of Diabetic Foot Ulcers | August 15, 2023 | August 30, 2024 |
| NCT04791449 | Recruiting | N/A | Exercise Enhances Wound Healing in Patients With Diabetic Foot Ulcers | October 10, 2021 | May 31, 2025 |
| NCT04232631 | Recruiting | Non-Invasive Testing to Evaluate Wound Healing in Diabetes | April 28, 2021 | September 2025 | |
| NCT06025422 | Recruiting | In-shoe Pressures Associated With Footwear Fit Guidelines | March 13, 2023 | November 29, 2024 | |
| NCT06024590 | Recruiting | Phase 4 | Outcomes of Irrisept Irrigation as an Adjunctive Treatment in the Management of Diabetic Foot Ulcers | October 3, 2023 | September 25, 2024 |
| NCT04497805 | Recruiting | Phase 2 | Clinical Study of ALLO-ASC-SHEET in Subjects With Diabetic Wagner Grade II Foot Ulcers | September 8, 2020 | June 2025 |
| NCT04831606 | Recruiting | N/A | Blue Light Photobiomodulation Therapy on Neuroischemic Patients | July 31, 2021 | August 2025 |
| NCT04920253 | Recruiting | N/A | Real World Evidence With the Debritom+ TM Novel Micro Water Jet Technology at a Single Wound Center | November 29, 2021 | December 2023 |
| NCT06004219 | Recruiting | N/A | Peer Support for Patients With Diabetic Foot Ulcers | November 21, 2023 | January 30, 2025 |
| NCT06003400 | Recruiting | N/A | Proof of Concept Open Label, Clinical Trial to Evaluate the Safety and Efficacy of the "FITT" Device in Diabetic Foot Ulcers Patients | March 29, 2023 | January 2025 |
| NCT06316115 | Recruiting | N/A | Effect On Paın And Anxıety Of Stress Ball Use Durıng Sharp Debrıdement | December 12, 2023 | April 10, 2024 |
| NCT05930210 | Recruiting | Phase 3 | A Study to Evaluate ENERGI-F703 GEL in Diabetic Foot Ulcer | May 30, 2023 | December 1, 2024 |
| NCT05804097 | Recruiting | Phase 4 | Does Increasing Oxygen Nurture Your Symptomatic Ischemic Ulcer Sufficiently? | October 8, 2021 | December 31, 2026 |
| NCT05772507 | Recruiting | N/A | Efficacy and Tolerance of URGO AWC_008 and URGO AWC_022 Dressings (EXPANSION) | August 22, 2023 | October 2024 |
| NCT06236750 | Recruiting | N/A | Post-Marketing Surveillance of Dehydrated Human Amnion/Chorion Membrane (DHACM) in Non-Ischemic Chronic Wounds | August 4, 2023 | January 2027 |
| NCT05046158 | Recruiting | N/A | Diabetic Foot Ulcers-Comparing Transforming Powder to Standard of Care | August 16, 2021 | December 31, 2023 |
| NCT05758545 | Recruiting | N/A | Trial to Evaluate the Safety and Effectiveness of Treatment With COMS One Device in Subjects With Diabetic Foot Ulcers | June 19, 2023 | June 19, 2025 |
| NCT04533152 | Recruiting | Prognostic Determinants in Patients With Diabetic Foot Ulcer. | November 24, 2021 | November 2029 | |
| NCT06403605 | Recruiting | N/A | Bioresorbable Glass Fiber Matrix in the Treatment of Diabetic Foot Ulcers | August 29, 2022 | December 31, 2024 |
| NCT05610865 | Recruiting | Phase 1 | Efficacy of Adipose Tissue Derived Stem Cells for the Treatment of Diabetic Foot Ulcers | November 20, 2020 | December 2023 |
| NCT05092620 | Recruiting | Adjunct Collection of Additional Biorepository Data From Patients Enrolled in Diabetic Foot Consortium (DFC) Trials | May 1, 2021 | December 30, 2024 | |
| NCT05094037 | Recruiting | N/A | Orthotic Treatment of Diabetic Foot Ulcers | December 4, 2023 | March 31, 2026 |
| NCT06185465 | Recruiting | N/A | Effectiveness and Safety of Using Prontosan to Treat Bacterial Biofilm | January 3, 2024 | February 28, 2025 |
| NCT05608187 | Recruiting | Phase 2 | Evaluating Safety and Biological Effect on Wound Healing of ILP100-Topical in Subjects With Diabetic Foot Ulcers | September 26, 2022 | December 2027 |
| NCT05132179 | Recruiting | N/A | Treating Diabetic Foot Ulcers, Comparing Two Topical Antimicrobial Agents, Dakin´s and Prontosan | February 1, 2022 | December 31, 2026 |
| NCT05607979 | Recruiting | Phase 2/Phase 3 | Restoring Tissue and Evaluating Novel Treatments for Efficacy in Wounds | December 15, 2022 | May 1, 2024 |
| NCT05595681 | Recruiting | Phase 1 | Effect of Mesenchymal Stem Cells on Healing of Foot Ulcers in Diabetes Patients. | December 15, 2022 | November 1, 2025 |
| NCT04210089 | Recruiting | N/A | Total Contact Soft Cast in Diabetic Foot Ulcers | October 13, 2020 | October 1, 2024 |
| NCT04247451 | Suspended | N/A | Diabetic Foot Surgery Patients: What is Their Metabolic Profile and Are Nutritional Goals Met | January 1, 2020 | December 31, 2024 |
| NCT06020664 | Suspended | Phase 1 | NOX1416 in Treatment of Chronic Non-Healing Diabetic Foot Ulcers (NTCDU) | August 16, 2023 | November 24, 2024 |
| NCT04178525 | Terminated | N/A | Clinical Trial Evaluating the Safety and Efficacy of the Use of Chitosan Gel in Patients With Chronic Wounds | August 2, 2018 | September 22, 2020 |
| NCT03654989 | Terminated | Phase 1/Phase 2 | Iontophoresis of Treprostinil to Enhance Wound Healing in Diabetic Foot Skin Ulcers | January 28, 2020 | December 7, 2021 |
| NCT03640988 | Terminated | N/A | The Effects of High Energy Acoustic Shock Wave Therapy on Local Skin Perfusion and DFUs | April 25, 2019 | January 3, 2021 |
| NCT04634838 | Terminated | N/A | Efficacy of Wound Dressings With Copper Oxide | February 2, 2021 | April 30, 2023 |
| NCT03509870 | Terminated | Phase 1 | Bone Marrow Derived Allogeneic Mesenchymal Stromal Cells to Non-healing Diabetic Foot Wounds | June 1, 2018 | April 1, 2020 |
| NCT04709419 | Terminated | N/A | Celliant Socks to Increase Tissue Oxygenation and Complete Wound Closure in Diabetic Foot Wounds | October 27, 2022 | December 1, 2023 |
| NCT00387101 | Terminated | Phase 3 | Efficacy and Safety Study in the Treatment of Chronic Diabetic Foot Ulcers | February 2006 | April 2008 |
| NCT03204149 | Terminated | N/A | Evaluation of Safety of Low Level Laser Device Treatment in Chronic Wounds | June 14, 2017 | June 14, 2019 |
| NCT00658957 | Terminated | Phase 2 | Prevention of Infection Using a Topical Gentamicin-Collagen Sponge in Diabetic Patients With An Uninfected Foot Ulcer | April 2008 | October 2009 |
| NCT02586519 | Terminated | N/A | Pressure-Sensing Insoles in the Neuropathic Ulcer Treatment Pathway | June 2016 | May 2019 |
| NCT00434538 | Terminated | Phase 3 | BST-DERMON Versus Standard of Care in the Treatment of Diabetic Foot Ulcers | February 2007 | November 2008 |
| NCT05281562 | Terminated | Phase 2/Phase 3 | Immunonutrition for Diabetic Foot Ulcers | July 1, 2022 | March 20, 2023 |
| NCT02202668 | Terminated | N/A | Transcutaneous Raman Spectroscope (TRS) Analyses of Diabetic Foot Ulcers | September 2014 | November 2014 |
| NCT02181621 | Terminated | N/A | A RCT to Compare the Effects of Two Wound Products on Biofilm Disruption in DFUs | August 2014 | October 2015 |
| NCT05494450 | Terminated | N/A | An Open, Non-comparative, Multicenter Investigation to Evaluate the Safety and Performance of Exufiber Ag+, a Gelling Fiber Silver Dressing, When Used in Medium to High Exuding Chronic Wounds | January 1, 2022 | November 29, 2022 |
| NCT05666570 | Terminated | The Avelle® Negative Pressure Wound Therapy System on Chronic Wounds | May 18, 2022 | March 21, 2023 | |
| NCT01966380 | Terminated | Phase 2 | Proof of Concept (Design Validation) in Patient With Hard to Heal Wounds Such as Pressure Ulcer, Diabetic Foot Ulcer and Leg Ulcer, Leia | September 2013 | March 2014 |
| NCT01840085 | Terminated | Phase 3 | Open-Label Study in Diabetic Foot Ulcers (DFU), to Evaluate Safety of 0.03% DSC127 Topical Gel in Chronic Use | December 2015 | December 2015 |
| NCT01816672 | Terminated | N/A | Efficacy of AutoloGel Therapy to Usual and Customary Care in Wagner gd 1 and 2 Diabetic Foot Ulcers. | April 2013 | July 2015 |
| NCT01608776 | Terminated | Phase 4 | RESPOND Restoring Equilibrium and Wound Stimulation to Promote Healing Of Non-healing DFUs | May 2012 | March 2013 |
| NCT01531517 | Terminated | Phase 3 | Study of the Efficacy of PedyPhar® Ointment on the Diabetic Foot Ulcers | July 2011 | July 2013 |
| NCT00368693 | Terminated | Phase 3 | Efficacy and Safety Study of Dermal-Living Skin Replacement to Treat Diabetic Foot Ulcers | August 2005 | September 2007 |
| NCT00820703 | Terminated | Phase 1/Phase 2 | The ASCEND Study: A Study to Investigate the Safety and Clinical Effect of Nexagon to Treat Slow Healing Diabetic Foot Ulcers | April 2009 | December 2009 |
| NCT04123093 | Terminated | N/A | Safety and Efficacy of the Noxsano Wound Care Bandage | August 9, 2019 | September 9, 2020 |
| NCT04134143 | Terminated | Phase 1 | Multiple Applications of ExpressGraft-C9T1 Skin Tissue as a Treatment for Diabetic Foot Ulcers | November 7, 2019 | December 30, 2020 |
| NCT03997526 | Terminated | 3C Patch® Medicare Claims Study | July 15, 2020 | February 21, 2022 | |
| NCT04240574 | Terminated | N/A | Debritom - Micro Water Jet Technology and Wound Healing | January 24, 2020 | August 6, 2021 |
| NCT02086955 | Unknown status | N/A | Outpatient Nurse Managed Counseling Program for Patients With Diabetic Foot Ulceration | February 2013 | February 2016 |
| NCT04464213 | Unknown status | Phase 1 | Human Placental Mesenchymal Stem Cells Treatment on Diabetic Foot Ulcer | November 1, 2020 | December 31, 2023 |
| NCT04210609 | Unknown status | N/A | Effectiveness of Vaporous Hyperoxia Therapy (VHT) in the Treatment of Chronic Diabetic Foot Ulcers | October 4, 2021 | October 3, 2022 |
| NCT03781024 | Unknown status | A Subjective Observational Study of Patients Using Medicated Footbath/Footwash Treatment in Podiatry Care | December 1, 2018 | June 1, 2022 | |
| NCT05368142 | Unknown status | Phase 4 | Nocardia Cell Wall Skeleton for the Treatment of Diabetic Foot Ulcer Wounds | May 20, 2022 | December 31, 2023 |
| NCT05274295 | Unknown status | N/A | Open Label Single Arm Proof of Concept Trial to Evaluate the Efficacy and Safety of Cytori Celution System in Diabetic Leg Ulcers | February 28, 2022 | April 30, 2022 |
| NCT02087215 | Unknown status | Phase 1 | Effect of Local Application of Boron on Diabetic Foot Ulcers | January 2014 | March 2015 |
| NCT02209662 | Unknown status | N/A | Safety and Efficacy Study of APIC-PRP in Non-healing Diabetic Foot Ulcers | October 2014 | December 2015 |
| NCT02326337 | Unknown status | N/A | Efficacy, Safety and Economic Benefits of Topical Wound Oxygen Therapy in the Treatment of Chronic Diabetic Foot Ulcers | October 2014 | December 15, 2018 |
| NCT02413086 | Unknown status | N/A | Effectiveness and Safety of Early-Stage Amputation and External Herbs Chitosan for Diabetic Foot Ulcer | April 2015 | |
| NCT05145140 | Unknown status | Phase 1 | A Clinical Intervention Study of Tangningtongluo on Diabetic Foot Ulcer | January 15, 2022 | March 31, 2023 |
| NCT05135130 | Unknown status | Retrospective Record-review Study in Patients Who Had Diabetic Foot Ulcer | October 4, 2021 | January 2022 | |
| NCT02742233 | Unknown status | Phase 4 | Dipeptidyl Peptidase 4 Inhibition Facilitate Healing of Diabetic Ulcers | November 2015 | November 2017 |
| NCT05089890 | Unknown status | N/A | Clinical Investigation of Sorbact® Dressings | October 2021 | February 28, 2022 |
| NCT04437537 | Unknown status | Pilot Study of PHOENIX Impact on Wound Microbiome | May 15, 2022 | January 1, 2023 | |
| NCT05076955 | Unknown status | Early Phase 1 | Evaluating the Healing of Diabetic Foot Ulcers With Compounded Anti-Infective Irrigation Therapy | March 31, 2021 | December 2022 |
| NCT02972528 | Unknown status | Phase 1/Phase 2 | The Use of Allogenic Platelet Rich Plasma for the Treatment of Diabetic Foot Ulcer | February 3, 2018 | September 2020 |
| NCT02989961 | Unknown status | Phase 1/Phase 2 | Safety and Efficacy of Resticutis Compared to Platelet-Poor Plasma for Treating Diabetic Foot Ulcers | November 15, 2013 | November 2019 |
| NCT04280016 | Unknown status | N/A | The Effect of Exercise on Wound Healing While Off-loading | May 14, 2021 | May 2023 |
| NCT03934944 | Unknown status | N/A | A Feasibility Study Comparing Usual Foot Education and Phone App Alerts in Patients With Increased Risk of Diabetic Foot | February 10, 2019 | April 2023 |
| NCT01493895 | Unknown status | Phase 1/Phase 2 | Study Assessing Safety and Efficacy of B-cure Laser Treating Diabetic Chronic Wounds | ||
| NCT00389636 | Unknown status | N/A | TheraGauze™ Alone and Regranex®Gel 0.01% Plus TheraGauze™ in the Treatment of Wagner Stage I Diabetic Foot Ulcers | September 2006 | July 2008 |
| NCT01342497 | Unknown status | Phase 2 | Oral BBR-012 in the Treatment of Diabetic Foot Ulcers, Proof of Concept Study | July 2011 | August 2012 |
| NCT03010215 | Unknown status | N/A | Treatment of Chronic Diabetic Foot Ulcers by Minimally Invasive Surgery | January 2010 | December 2020 |
| NCT00926068 | Unknown status | Phase 2 | Safety and Efficacy of HO/03/03 10μg in the Treatment of Plantar Neuropathic Diabetic Foot Ulcers | February 2010 | |
| NCT03041844 | Unknown status | N/A | Enhanced Ultrasound Treatment of Chronic Wounds With Monitoring of Healing and Quality of Life Outcomes | January 2017 | March 2023 |
| NCT00839865 | Unknown status | Phase 2 | Trial of Herb Yuyang Ointment to Diabetic Foot Ulcer | November 2008 | March 2011 |
| NCT03078933 | Unknown status | N/A | A Feasibility Study of Advance Plasma Therapy001 Plasma/Nitric Oxide Therapy for the Treatment of Diabetic Foot Ulcers | March 20, 2017 | July 2018 |
| NCT03890172 | Unknown status | Efficacy of Platelets Rich Plasma as a Therapeutic Tool in Diabetic Foot Ulcers | July 30, 2019 | December 30, 2021 | |
| NCT03110796 | Unknown status | N/A | Assessment of the Efficacy and Safety of a New Medical Device in the Local Treatment of Diabetic Foot Ulcers | July 31, 2017 | January 2020 |
| NCT03166423 | Unknown status | Phase 1/Phase 2 | Efficacy and Safety of Snail Slime and Natural Extracts for Healing in Diabetic Foot Ulcers | November 12, 2015 | July 1, 2017 |
| NCT03215953 | Unknown status | N/A | Offloading Interventions for Diabetic Foot Problems in Upper Egypt | February 1, 2019 | September 1, 2020 |
| NCT03248466 | Unknown status | Early Phase 1 | PRG Combined With Autologous BMMSCs for Treatment of Diabetic Foot Ulcer | August 30, 2017 | July 1, 2020 |
| NCT03414216 | Unknown status | N/A | Surgical Offloading Procedures for Diabetic Foot Ulcers | March 1, 2018 | December 31, 2019 |
| NCT04716790 | Unknown status | N/A | Comparison Between the Effect of Ultrasound Debridement and Conventional Treatment in Diabetic Foot Ulcers (DFU). | April 20, 2021 | June 23, 2023 |
| NCT00776854 | Unknown status | Phase 1 | Bioburden Reduction of Diabetic Foot Ulcer | November 2008 | November 2009 |
| NCT03458286 | Unknown status | N/A | A Study Measuring the Effectiveness of Combined Modulated Ultrasound and Electric Current Stimulation as an Adjunctive Treatment in Treating Diabetic Foot Ulcers | April 2018 | October 2018 |
| NCT03687320 | Unknown status | N/A | Laser Therapy for At-Home Treatment of DIabetic Foot Ulcers | December 2, 2019 | October 1, 2023 |
| NCT03687580 | Unknown status | N/A | Laser Therapy for At-Home Treatment of Diabetic Foot Ulcers - Canada | February 1, 2019 | October 1, 2023 |
| NCT04098562 | Unknown status | Phase 2 | Efficacy of LL-37 Cream on Bacteria Colonization, Inflammation Response and Healing Rate of Diabetic Foot Ulcers | October 2019 | January 2020 |
| NCT04117269 | Unknown status | N/A | External Shoe Lift to Improve Healing and Adherence in Patients With Diabetic Foot Ulcers | November 15, 2019 | December 2023 |
| NCT04310137 | Unknown status | N/A | Self-directed Versus Therapist-directed Re-loading on Incidence of Ulcer Recurrence | May 1, 2021 | December 2023 |
| NCT04093635 | Unknown status | Negative Pressure Wound Therapy in the Management of Diabetic Foot Ulcers | November 2019 | January 2021 | |
| NCT04323462 | Unknown status | Phase 4 | Intensive Glycemic Control For Diabetic Foot Ulcer Healing | October 1, 2021 | December 2022 |
| NCT04567563 | Unknown status | N/A | Remote Ischemic Conditioning and Diabetic Foot Ulcers | November 2020 | November 2022 |
| NCT04163055 | Unknown status | Phase 4 | Fluorescence Image-Guided Healing Trial | January 1, 2021 | December 31, 2022 |
| NCT03725917 | Unknown status | N/A | Patients With Diabetic Neuropathy Who Receive Physiotherapy Treatment Will Have a Decrease in Diabetic Foot Ulcers | March 25, 2019 | December 1, 2019 |
| NCT03855514 | Unknown status | N/A | Randomized Clinical Study Assessing NuShield Versus Standard of Care in Diabetic Foot Ulcers | February 8, 2019 | December 30, 2021 |
| NCT04198441 | Unknown status | N/A | The Omeza Protocol for Chronic Ulcers | June 2, 2020 | December 2021 |
| NCT03740581 | Unknown status | N/A | Intensive Versus Conventional Glycemic Control in Diabetic Foot Ulcer Healing | November 1, 2017 | June 30, 2019 |
| NCT03827902 | Withdrawn | Diabetic Foot Ulcer and Wound Infection | July 9, 2019 | April 2, 2020 | |
| NCT03296436 | Withdrawn | Early Phase 1 | A Pilot Study to Assess the Efficacy of NEOX® CORD 1K® in the Treatment of Complex Diabetic Wounds | January 2020 | October 2021 |
| NCT03993990 | Withdrawn | N/A | Effects of Empowerment-based Program on Post-discharge Glycemic Control, and Foot Ulcer | August 1, 2019 | July 31, 2021 |
| NCT01623882 | Withdrawn | Clinical Evaluation of the Combined Use of Apligraf® and the SNaP® Pressure Wound Therapy System | June 2012 | December 2015 | |
| NCT04332003 | Withdrawn | N/A | Evaluating Remote Ischemic Conditioning (RIC) and Standard of Care vs. Sham Therapy and Standard Care | January 1, 2021 | February 6, 2021 |
| NCT00338702 | Withdrawn | Phase 4 | A Randomized, Controlled Trial of Autologous Platelet Gel Treatment in Diabetic Foot Ulcers | March 2008 | October 2009 |
| NCT05024656 | Withdrawn | N/A | AmnioExcel® Plus vs SOC in the Management of Diabetic Foot Ulcers | September 2021 | June 2024 |
| NCT02347709 | Withdrawn | Differential Characteristics of Neuropathy in Type 2 Diabetics With and Without Lower Extremity Wounds | December 2014 | December 1, 2017 | |
| NCT03854695 | Withdrawn | Study to Evaluate Bacterial Activity That Drives the Progression of Clinical Infection | February 1, 2019 | June 1, 2024 | |
| NCT02990832 | Withdrawn | N/A | Diabetes Foot Care Clinical Pathway Project - Exciton Technologies Inc | January 2017 | May 2018 |
| NCT03675269 | Withdrawn | N/A | Adjunctive Hyperbaric Oxygen Therapy (HBOT) for Lower Extermity Diabetic Ulcer: | September 5, 2018 | September 2019 |
| NCT04285710 | Withdrawn | N/A | Adjunctive Phototherapy Treatment of Infected Diabetic Ulcers | June 2021 | April 2022 |