Annotation Detail
Information
- Associated Genes
- TIMP1
- Associated Variants
-
TIMP1 MUTATION
TIMP1 MUTATION - Associated Disease
- Carcinoma of lung
- Source Database
- DisGeNET
- Description
- We compared the frequency of single nucleotide polymorphisms in genes coding for matrix proteinases (MMP1, MMP2, MMP3, MMP9, MMP12) as well as tissue inhibitor of metalloproteinases (TIMP1) in two groups of subjects: COPD patients (54 subjects) and COPD patients diagnosed for lung cancer occurrence (53 subjects).The levels of the respective proteins in blood serum were also analyzed.
- Pubmed
- 25292126
- Section of the abstract supporting the evidence
- MATERIALS AND METHODS
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00190009310456212
Drugs