acute pyelonephritis

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Information
Disease name
acute pyelonephritis
Disease ID
DOID:559
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04682834 Available Expanded Access Use of Sulopenem Etzadroxil/Probenecid for Complicated Urinary Tract Infection
NCT01928433 Completed Phase 2 Finafloxacin for the Treatment of cUTI and/or Acute Pyelonephritis December 2012 October 2015
NCT02034851 Completed Dexamethasone Administration in 1st Episode of Febrile Urinary Tract Infection April 2013 June 2019
NCT02166476 Completed Phase 3 Efficacy/Safety of Meropenem-Vaborbactam Compared to Piperacillin-Tazobactam in Adults With cUTI and AP November 20, 2014 April 28, 2016
NCT02168946 Completed Phase 3 Efficacy, Safety, Tolerability of Vabomere Compared to Best Available Therapy in Treating Serious Infections in Adults July 2014 July 21, 2017
NCT02420366 Completed Study of Cases of Serious Infections Due to Carbapenem-Resistant Enterobacteriaceae May 2014 January 2015
NCT02486627 Completed Phase 3 A Study of Plazomicin Compared With Meropenem for the Treatment of Complicated Urinary Tract Infection (cUTI) Including Acute Pyelonephritis (AP) January 11, 2016 September 22, 2016
NCT02753946 Completed Phase 2/Phase 3 Safety and Efficacy of ZTI-01 (IV Fosfomycin) vs Piperacillin/Tazobactam for Treatment cUTI/AP Infections April 2016 May 30, 2017
NCT03445195 Completed Phase 2 Evaluation of Safety and Efficacy of Intravenous Sulbactam-ETX2514 in the Treatment of Hospitalized Adults With Complicated Urinary Tract Infections January 17, 2018 May 17, 2018
NCT03477422 Completed Phase 3 CSE-1034 (Ceftriaxone+ Sulbactam+ EDTA) Compared to Meropenem in Complicated Urinary Tract Infections (cUTIs) Caused by ESBL Producing Gram Negative Bacteria January 11, 2014 May 8, 2017
NCT06141395 Completed NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification November 16, 2023 March 14, 2024
NCT03757234 Completed Phase 2 IV or IV/PO Omadacycline vs. IV/PO Levofloxacin for the Treatment of Acute Pyelonephritis November 19, 2018 July 24, 2019
NCT03788967 Completed Phase 3 Study to Assess the Efficacy, Safety and Pharmacokinetics of Orally Administered Tebipenem Pivoxil Hydrobromide (SPR994) Compared to Intravenous Ertapenem in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) June 3, 2019 May 27, 2020
NCT03840148 Completed Phase 3 Safety and Efficacy Study of Cefepime/VNRX-5133 in Patients With Complicated Urinary Tract Infections August 7, 2019 December 14, 2021
NCT04667195 Completed Clinical Characteristics of Acutely Hospitalized Adults With Acute Pyelonephritis March 1, 2021 June 1, 2022
NCT04686318 Completed Accuracy of Infection Biomarkers in the Investigation of Patients With Suspected Acute Pyelonephritis March 1, 2021 June 1, 2022
NCT04882085 Completed Phase 4 Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults August 26, 2021 August 31, 2023
NCT01096849 Completed Phase 2 A Study of Plazomicin Compared With Levofloxacin for the Treatment of Complicated Urinary Tract Infection (cUTI) and Acute Pyelonephritis (AP) July 13, 2010 April 3, 2012
NCT03630081 Not yet recruiting Phase 3 Study of Cefepime-tazobactam (FEP-TAZ) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) January 2024 February 2026
NCT05905055 Recruiting Phase 3 P3 Study to Assess Efficacy and Safety of Cefepime/Nacubactam and Aztreonam/Nacubactam Versus Best Available Therapy for Adults With Infection Due to Carbapenem Resistant Enterobacterales September 22, 2023 February 2025
NCT05887908 Recruiting Phase 3 Efficacy and Safety of Cefepime/Nacubactam or Aztreonam/Nacubactam Compared to Imipenem/Cilastatin in Subjects With Complicated Urinary Tract Infections or Acute Uncomplicated Pyelonephritis May 23, 2023 November 2024
NCT06059846 Recruiting Phase 3 A Study of Oral Tebipenem Pivoxil Hydrobromide (TBP-PI-HBr) Compared to Intravenous Imipenem-cilastatin in Participants With Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) December 21, 2023 December 2025
NCT05674032 Recruiting Bacterial Metallophores in the Diagnosis of Acute Pyelonephritis June 24, 2020 December 2024
NCT04654507 Recruiting Phase 3 Efficacy of Corticosteroids in Reducing Renal Scarring in Acute Pyelonephritis in Children March 3, 2021 December 2024
NCT04979806 Recruiting Phase 3 Study of Cefepime-zidebactam (FEP-ZID) in Complicated Urinary Tract Infection (cUTI) or Acute Pyelonephritis (AP) August 28, 2022 May 2024
NCT02537847 Unknown status Phase 2 Sitafloxacin and Ertapenem Treatment for Acute Pyelonephritis Caused by Escherichia Coli November 2012 May 2016
NCT05060419 Unknown status Phase 2 Meropenem-FL058 Phase 2 Study in the Treatment of Complicated Urinary Tract Infections October 8, 2021 August 31, 2022
Disase is a (Disease Ontology)
DOID:11400
Cross Reference ID (Disease Ontology)
ICD10CM:N10
Cross Reference ID (Disease Ontology)
ICD9CM:590.1
Cross Reference ID (Disease Ontology)
NCI:C123215
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:155862004
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0520575