Annotation Detail
Information
- Associated Genes
- TIMP1
- Associated Variants
-
TIMP1 MUTATION
TIMP1 MUTATION - Associated Disease
- breast carcinoma
- Source Database
- DisGeNET
- Description
- Angiogenic cytokines which are known to regulate tumorigenicity and angiogenesis, such as GM-CSF, IGFBP-2, VEGF, and uPA, were inhibited, while several anti-angiogenic cytokines such as TIMP-1 and Serpin E1were induced in breast cancer cells.
- Pubmed
- 24941346
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00977190739489092
Drugs