chr2:136114349:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr2:136,871,919-136,876,747 
hg38 chr2:136,114,349-136,119,177

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.027 squamous cell carcinoma NA BeFree,GAD,LHGDN Detail
0.120 Neoplastic Cell Transformation NA CTD_human Detail
<0.001 cerebral infarction NA BeFree Detail
0.002 Malignant tumor of cervix ATO inhibited CXCR4-mediated cervical cancer cell invasion in vitro and distant ... BeFree 25047463 Detail
0.002 Malignant tumor of cervix Epigenetic silencing of CXCR4 promotes loss of cell adhesion in cervical cancer. BeFree 25114911 Detail
<0.001 chondrosarcoma NA BeFree Detail
<0.001 choriocarcinoma NA BeFree Detail
<0.001 ulcerative colitis NA BeFree Detail
<0.001 Colonic Polyps NA BeFree Detail
0.008 colorectal carcinoma The association of CXCR4 expression with prognosis and clinicopathological indic... BeFree 24422942 Detail
0.008 colorectal carcinoma SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colore... BeFree 25150783 Detail
0.008 colorectal carcinoma Treatment of CRC cells with the CXCR4 antagonist AMD3100 attenuated SEMA3F knock... BeFree 25866254 Detail
0.011 Colorectal Neoplasms NA BeFree,LHGDN Detail
0.002 Coronary heart disease NA GAD Detail
<0.001 craniopharyngioma High expression levels of CXCL12 and CXCR4 predict recurrence of adamanti-nomato... BeFree 24934367 Detail
0.004 adenoid cystic carcinoma NA BeFree,LHGDN Detail
<0.001 Phyllodes Tumor NA BeFree Detail
<0.001 Presenile dementia NA BeFree Detail
<0.001 Diabetes These observations demonstrate a potentially reno-protective role for CXCR4 in d... BeFree 25549045 Detail
<0.001 diabetes mellitus These observations demonstrate a potentially reno-protective role for CXCR4 in d... BeFree 25549045 Detail
0.005 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree,GAD Detail
<0.001 Diabetic Nephropathy Although CXCR4 expression was also increased in biopsy tissue from patients with... BeFree 25549045 Detail
<0.001 Drug abuse NA BeFree Detail
<0.001 Experimental Autoimmune Encephalomyelitis NA BeFree Detail
<0.001 endometriosis NA BeFree Detail
<0.001 Esophageal Neoplasms Moreover, therapy targeting the CXCL12/CXCR4 axis may open a new direction for t... BeFree 26130416 Detail
<0.001 Fanconi anemia NA BeFree Detail
<0.001 breast fibrocystic disease NA BeFree Detail
<0.001 Gastrointestinal Neoplasms NA BeFree Detail
<0.001 Gingival Diseases NA BeFree Detail
0.007 glioblastoma VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a ... BeFree,LHGDN 25676691 Detail
0.017 Glioma NA BeFree,LHGDN Detail
<0.001 Graves Disease NA BeFree Detail
<0.001 Hematological Disease NA BeFree Detail
<0.001 hemolytic-uremic syndrome NA BeFree Detail
<0.001 Hepatitis, Alcoholic NA BeFree Detail
<0.001 Herpes Simplex Infections NA BeFree Detail
<0.001 Von Hippel-Lindau syndrome NA BeFree Detail
0.095 HIV Infections Increased CXCR4 use of HIV-1 subtype C identified by population sequencing in pa... BeFree,GAD,LHGDN 24205895 Detail
0.095 HIV Infections The CX3CR1 A allele and lower genetic scores may restrict the switch of HIV-1 tr... BeFree,GAD,LHGDN 24750723 Detail
0.095 HIV Infections CXCR4 usage can emerge independently, in multiple lineages, along the course of ... BeFree,GAD,LHGDN 25032817 Detail
0.095 HIV Infections When pDC were depleted prior to HIV-1 infection, the induction of IFN-I and inte... BeFree,GAD,LHGDN 25077616 Detail
0.095 HIV Infections Furthermore, a mutated virus that is capable of using both CCR5 and CXCR4 as ent... BeFree,GAD,LHGDN 25330146 Detail
0.095 HIV Infections Our study demonstrates that individuals may be infected by minority X4 viruses f... BeFree,GAD,LHGDN 25730507 Detail
0.095 HIV Infections The interaction of HIV-1 and target cells involves sequential binding of the vir... BeFree,GAD,LHGDN 25966986 Detail
0.095 HIV Infections Chemokine receptors CXCR4 and CCR5 are indispensable co-receptors for HIV-1 entr... BeFree,GAD,LHGDN 26018859 Detail
0.095 HIV Infections HIV-1 Nef downregulates the viral entry receptor CD4 as well as the coreceptors ... BeFree,GAD,LHGDN 26178998 Detail
0.095 HIV Infections Treatment failure with drug-resistant virus is particularly interesting because ... BeFree,GAD,LHGDN 26339063 Detail
0.003 Hyperplasia NA LHGDN Detail
0.003 Immunologic Deficiency Syndromes NA BeFree Detail
<0.001 Immune System Diseases NA BeFree Detail
0.001 Inflammatory Bowel Diseases NA BeFree Detail
0.002 ischemia NA BeFree Detail
<0.001 Kidney Failure, Acute NA BeFree Detail
0.003 Kidney Neoplasm NA LHGDN Detail
0.010 leukemia There is marked evidence that the SDF-1/CXCR4 axis is involved in the pathogenes... BeFree,LHGDN 25070183 Detail
0.010 leukemia CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphobl... BeFree,LHGDN 26058076 Detail
0.010 chronic lymphocytic leukemia It has previously been shown that SDF1/CXCR4-induced migration is dependent on a... BeFree,GAD,LHGDN 25294819 Detail
0.010 chronic lymphocytic leukemia Circulating chronic lymphocytic leukemia (CLL) cells display an abnormal increas... BeFree,GAD,LHGDN 26282174 Detail
<0.001 Acute Erythroblastic Leukemia NA BeFree Detail
<0.001 lymphoid leukemia NA BeFree Detail
0.002 Acute lymphocytic leukemia NA BeFree Detail
0.009 Leukemia, Myelocytic, Acute CXCR4 expression accounts for clinical phenotype and outcome in acute myeloid le... BeFree,LHGDN 24500843 Detail
0.009 Leukemia, Myelocytic, Acute The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression. BeFree,LHGDN 25193961 Detail
0.009 Leukemia, Myelocytic, Acute Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML. BeFree,LHGDN 25294819 Detail
0.009 Leukemia, Myelocytic, Acute A designed peptide targeting CXCR4 displays anti-acute myelocytic leukemia activ... BeFree,LHGDN 25312253 Detail
0.009 Leukemia, Myelocytic, Acute Patients with defective NK cells showed a profound gene expression decrease in A... BeFree,LHGDN 26246143 Detail
<0.001 myeloid leukemia NA BeFree Detail
0.002 Myeloid Leukemia, Chronic Role of the hybrid Bcr/Abl kinase in the pathogenesis of chronic myeloid leukemi... BeFree 25265345 Detail
<0.001 Precursor B-Cell Lymphoblastic Leukemia-Lymphoma NA BeFree Detail
<0.001 Leukemia, T-Cell NA BeFree Detail
<0.001 Adult T-Cell Lymphoma/Leukemia NA BeFree Detail
0.001 leukopenia NA BeFree Detail
<0.001 Liver diseases NA BeFree Detail
0.003 Liver neoplasms NA BeFree,GAD Detail
0.003 Lung diseases NA LHGDN Detail
0.022 Lung Neoplasms Immunophenotypic analysis of lung tumor cells intravenously injected or spontane... BeFree,LHGDN 26141860 Detail
0.004 Lupus Erythematosus, Systemic NA BeFree,LHGDN Detail
0.003 Lymphatic Metastasis NA BeFree,GAD Detail
0.002 lymphoma NA BeFree Detail
0.003 Lymphoma, Follicular NA BeFree,LHGDN Detail
0.002 Lymphoma, Non-Hodgkin NA GAD Detail
<0.001 lymphopenia NA BeFree Detail
0.004 Malignant neoplasm of stomach Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine re... BeFree 24929539 Detail
0.004 medulloblastoma These results demonstrate crosstalk among WIP1, CXCR4 and GRK5, which may be imp... BeFree,LHGDN 24632620 Detail
0.004 medulloblastoma Role of CXCL12 and CXCR4 in normal cerebellar development and medulloblastoma. BeFree,LHGDN 25400097 Detail
0.024 melanoma Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with ... BeFree,LHGDN 25211166 Detail
0.024 melanoma Deregulation of the CXCR4/CXCL12 axis was reported in melanoma tumorigenesis whi... BeFree,LHGDN 25839711 Detail
0.024 melanoma PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma. BeFree,LHGDN 26205821 Detail
<0.001 multiple endocrine neoplasia type 2B NA BeFree Detail
<0.001 meningioma NA BeFree Detail
<0.001 Monoclonal Gammopathy of Undetermined Significance NA BeFree Detail
0.002 Mouth Neoplasms NA GAD Detail
0.006 multiple myeloma In 176 paired clinical samples, BTK and CXCR4 expression was lower in myeloma ce... BeFree 25083818 Detail
0.006 multiple myeloma It has previously been shown that SDF1/CXCR4-induced migration is dependent on a... BeFree 25294819 Detail
0.006 multiple myeloma Several chemokines/chemokine receptors such as CXCL12, CCL3, CXCR4 and CCR1 attr... BeFree 25962684 Detail
0.005 multiple sclerosis NA BeFree,GAD Detail
<0.001 Mycobacterium avium-intracellulare Infection NA BeFree Detail
<0.001 myelofibrosis This trafficking pattern could not be attributed to discordant expression of int... BeFree 25461253 Detail
0.003 myositis NA LHGDN Detail
0.246 Neoplasm Metastasis In addition, a significant association was revealed between positive CXCR4 expre... BeFree,CTD_human,LHGDN 24422942 Detail
0.246 Neoplasm Metastasis Because breast cancer patient survival inversely correlates with metastasis, we ... BeFree,CTD_human,LHGDN 24467226 Detail
0.246 Neoplasm Metastasis Furthermore, coexpression of HIF-1α and CXCR4 was significantly higher in patien... BeFree,CTD_human,LHGDN 24618817 Detail
0.246 Neoplasm Metastasis This study reveals the highly plastic and dynamic nature of CXCR4 expression in ... BeFree,CTD_human,LHGDN 24651452 Detail
0.246 Neoplasm Metastasis Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by dere... BeFree,CTD_human,LHGDN 24840182 Detail
0.246 Neoplasm Metastasis Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine re... BeFree,CTD_human,LHGDN 24929539 Detail
0.246 Neoplasm Metastasis The role of both CXCR4 (a chemokine inducing cytoskeletal rearrangement and cell... BeFree,CTD_human,LHGDN 24992171 Detail
0.246 Neoplasm Metastasis More promisingly, miR-302a inhibited the invasion and metastasis of breast cance... BeFree,CTD_human,LHGDN 25030358 Detail
0.246 Neoplasm Metastasis Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A... BeFree,CTD_human,LHGDN 25047463 Detail
0.246 Neoplasm Metastasis These findings demonstrate the first evidence that epigenetic silencing of CXCR4... BeFree,CTD_human,LHGDN 25114911 Detail
0.246 Neoplasm Metastasis CXCR7 was not detectable in secondary tumors but CXCR4 was expressed. BeFree,CTD_human,LHGDN 25227814 Detail
0.246 Neoplasm Metastasis CXCR4 is a marker of poor prognosis in various neoplasms, correlating with metas... BeFree,CTD_human,LHGDN 25231113 Detail
0.246 Neoplasm Metastasis The subsequent increase in circulating granulocyte number, with an increase in s... BeFree,CTD_human,LHGDN 25270220 Detail
0.246 Neoplasm Metastasis The chemokine receptor CXCR4 and signal transducer and activator of transcriptio... BeFree,CTD_human,LHGDN 25310198 Detail
0.246 Neoplasm Metastasis Our findings suggest that ΔNP63α regulation of CXCR4 may have strong implication... BeFree,CTD_human,LHGDN 25376609 Detail
0.246 Neoplasm Metastasis SNCG, MAP2, SDF-1 and CXCR4 may play an important role in the carcinogenesis, pr... BeFree,CTD_human,LHGDN 25400739 Detail
0.246 Neoplasm Metastasis The HIF-1α/CXCR4 pathway supports hypoxia-induced metastasis of human osteosarco... BeFree,CTD_human,LHGDN 25444927 Detail
0.246 Neoplasm Metastasis In conclusion, our result shows that high CXCR4 expression is associated with IH... BeFree,CTD_human,LHGDN 25471741 Detail
0.246 Neoplasm Metastasis The present study indicates that the inflammatory cytokine, TNF-α, partially fun... BeFree,CTD_human,LHGDN 25503960 Detail
0.246 Neoplasm Metastasis Downregulation of CXCR4 by SDF-KDEL in SBC-5 cells inhibits their migration in v... BeFree,CTD_human,LHGDN 25504108 Detail
0.246 Neoplasm Metastasis These results indicated that miR-518c-5p regulates the growth and metastasis of ... BeFree,CTD_human,LHGDN 25536052 Detail
0.246 Neoplasm Metastasis Finally, IL-24 when combined with CXCR4 inhibitors (AMD3100, SJA5) or with CXCR4... BeFree,CTD_human,LHGDN 25775124 Detail
0.246 Neoplasm Metastasis Treatment of CRC cells with the CXCR4 antagonist AMD3100 attenuated SEMA3F knock... BeFree,CTD_human,LHGDN 25866254 Detail
0.246 Neoplasm Metastasis High expression of CXCR4 may help oral squamous cancer cells invade local tissue... BeFree,CTD_human,LHGDN 25866764 Detail
0.246 Neoplasm Metastasis Recent evidence suggests that CXCR4-mediated proliferation and metastasis of tum... BeFree,CTD_human,LHGDN 25884570 Detail
0.246 Neoplasm Metastasis Downregulation of the CXCR4/CXCL12 axis thus reduces cancer growth and metastasi... BeFree,CTD_human,LHGDN 25960214 Detail
0.246 Neoplasm Metastasis Here, we show that CD133(+)/CXCR4(+) cancer-initiating cells (CIC) directly isol... BeFree,CTD_human,LHGDN 26141860 Detail
0.246 Neoplasm Metastasis The chemokine receptor CXCR4 is active in melanoma metastasis, although the mech... BeFree,CTD_human,LHGDN 26205821 Detail
0.246 Neoplasm Metastasis Chemokine receptor CXCR4 is involved in tumor growth, angiogenesis and metastasi... BeFree,CTD_human,LHGDN 26321665 Detail
<0.001 multiple endocrine neoplasia NA BeFree Detail
<0.001 nervous system disorder NA BeFree Detail
0.120 Neuralgia NA CTD_human Detail
0.008 neuroblastoma The present study indicates that the inflammatory cytokine, TNF-α, partially fun... BeFree,GAD,LHGDN 25503960 Detail
0.008 neuroblastoma Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and ind... BeFree,GAD,LHGDN 25774696 Detail
0.008 neuroblastoma Finally, coexpression of CXCR4 and CXCR7 receptors significantly and selectively... BeFree,GAD,LHGDN 25955316 Detail
<0.001 neutropenia NA BeFree Detail
<0.001 obesity NA BeFree Detail
<0.001 Opportunistic Infections NA BeFree Detail
<0.001 Degenerative polyarthritis Although chemokine stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 ... BeFree 24516346 Detail
0.011 osteosarcoma Hypoxia promotes migration and induces CXCR4 expression via HIF-1α activation in... BeFree,LHGDN 24618817 Detail
0.011 osteosarcoma Our study provides further evidence of the contributions of hypoxia and the HIF-... BeFree,LHGDN 25444927 Detail
0.011 osteosarcoma Higher CXCR4 mRNA levels were detected in the osteosarcoma cell lines compared t... BeFree,LHGDN 25890096 Detail
0.006 ovarian carcinoma Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA i... BeFree 25149650 Detail
0.012 Pancreatic Neoplasm NA BeFree,LHGDN Detail
<0.001 Periodontal Diseases NA BeFree Detail
<0.001 pituitary adenoma NA BeFree Detail
0.001 Pituitary Diseases NA BeFree Detail
0.003 Pituitary Neoplasms NA BeFree,LHGDN Detail
<0.001 pneumonia This two-layered microfluidic system provides a feasible platform for perfusion ... BeFree 25486073 Detail
<0.001 polyps NA BeFree Detail
<0.001 prolactinoma NA BeFree Detail
0.031 Prostatic Neoplasms Here we show that, in the LNCaP prostate-tumor cell line, androgens coordinate t... BeFree,LHGDN 25884570 Detail
<0.001 pterygium NA BeFree Detail
<0.001 pulmonary fibrosis NA BeFree Detail
0.009 rhabdomyosarcoma NA BeFree,LHGDN Detail
<0.001 sarcoidosis NA BeFree Detail
0.006 systemic scleroderma NA BeFree,LHGDN Detail
<0.001 Septicemia NA BeFree Detail
0.009 Stomach Neoplasms NA BeFree,LHGDN Detail
<0.001 Cerebrovascular accident NA BeFree Detail
<0.001 Superinfection HIV-1 Nef downregulates the viral entry receptor CD4 as well as the coreceptors ... BeFree 26178998 Detail
<0.001 synovial sarcoma Prognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localize... BeFree 25613038 Detail
<0.001 Thrombocythemia, Essential NA BeFree Detail
0.009 Thyroid Neoplasm NA BeFree,LHGDN Detail
<0.001 thyroiditis NA BeFree Detail
<0.001 tuberculosis NA BeFree Detail
0.003 Tuberculosis, Pulmonary NA BeFree,LHGDN Detail
<0.001 uveitis NA BeFree Detail
<0.001 Vascular Diseases NA BeFree Detail
0.002 Virus Diseases NA BeFree Detail
<0.001 B-Cell Lymphomas NA BeFree Detail
0.001 diffuse large B-cell lymphoma CXCR4 expression enhances diffuse large B cell lymphoma dissemination and decrea... BeFree 25231113 Detail
<0.001 T-Cell Lymphoma NA BeFree Detail
<0.001 Lymphoma, T-Cell, Cutaneous Importantly, our results demonstrate that BZ inhibits expression of the chemokin... BeFree 25681335 Detail
0.002 severe combined immunodeficiency NA BeFree Detail
<0.001 Polyendocrinopathies, Autoimmune NA BeFree Detail
0.003 Liver failure NA LHGDN Detail
<0.001 Synovial Cyst NA BeFree Detail
<0.001 acute leukemia NA BeFree Detail
<0.001 Hamman-Rich syndrome NA BeFree Detail
<0.001 Hypogammaglobulinemia NA BeFree Detail
<0.001 Epstein-Barr Virus Infections NA BeFree Detail
0.001 Small cell carcinoma of lung Thus, CXCR4 may prove to be a promising target for the prevention and effective ... BeFree 25504108 Detail
<0.001 Genital ulceration NA BeFree Detail
<0.001 Thyroid Gland Follicular Adenoma NA BeFree Detail
<0.001 Cutaneous Melanoma Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with ... BeFree 25211166 Detail
0.001 esophageal carcinoma Moreover, therapy targeting the CXCL12/CXCR4 axis may open a new direction for t... BeFree 26130416 Detail
<0.001 congenital heart disease NA BeFree Detail
<0.001 Idiopathic pulmonary hypertension NA BeFree Detail
0.002 Malignant neoplasm of mouth These results indicated that miR-518c-5p regulates the growth and metastasis of ... BeFree 25536052 Detail
0.002 Malignant neoplasm of mouth The CXCL12-CXCR4 biological axis consisting of the chemotactic factor CXCL12 and... BeFree 25866764 Detail
0.003 Secondary malignant neoplasm of lung This study reveals the highly plastic and dynamic nature of CXCR4 expression in ... BeFree 24651452 Detail
0.003 Secondary malignant neoplasm of lung The mechanism of pulmonary metastasis inhibition involved decreased expression o... BeFree 25402182 Detail
0.003 Secondary malignant neoplasm of lung Importantly, we show that knockdown of either CXCR4 or MIF abrogates MSC homing ... BeFree 25712213 Detail
0.003 Secondary malignant neoplasm of lung Additionally, IL-24, when combined with CXCR4 inhibitors exhibited enhanced anti... BeFree 25775124 Detail
<0.001 Secondary malignant neoplasm of kidney In in vivo experiments, the knockout of CXCR4 suppressed the development of meta... BeFree 25504108 Detail
0.003 Secondary malignant neoplasm of bone We compared the expression levels of C-X-C chemokine receptor type 4 (CXCR4) in ... BeFree 25504108 Detail
0.003 Secondary malignant neoplasm of bone In addition, we used a xenograft mouse model established by intracardiac injecti... BeFree 25773070 Detail
<0.001 acute myocardial infarction NA BeFree Detail
<0.001 Chronic obstructive asthma (with obstructive pulmonary disease) CXCL12/CXCR4 and CCL19/CCR7 enhanced fibrocyte transmigration in the Asthma AE g... BeFree 25441632 Detail
<0.001 Malnutrition NA BeFree Detail
<0.001 Cicatrix, Hypertrophic NA BeFree Detail
<0.001 Aortic Aneurysm, Abdominal NA BeFree Detail
0.001 Agenesis of corpus callosum NA BeFree Detail
0.008 Tumor Progression The role of both CXCR4 (a chemokine inducing cytoskeletal rearrangement and cell... BeFree 24992171 Detail
0.008 Tumor Progression In the network of chemokine signaling pathways, recent reports have described th... BeFree 25114911 Detail
0.008 Tumor Progression Stromal cell-derived factor 1 (SDF-1) and its receptor, CXCR4, play an important... BeFree 25150783 Detail
0.008 Tumor Progression The expression of chemokine receptors CXCR3 and CXCR4 in predicting postoperativ... BeFree 25232565 Detail
0.003 Rhabdomyosarcoma, Embryonal NA LHGDN Detail
<0.001 mucoepidermoid carcinoma NA BeFree Detail
0.003 cholangiocarcinoma NA BeFree,LHGDN Detail
0.004 hemangioblastoma NA BeFree,LHGDN Detail
<0.001 Adult Acute Myeloblastic Leukemia NA BeFree Detail
<0.001 pediatric acute myeloblastic leukemia NA BeFree Detail
0.001 uveal melanoma NA BeFree Detail
<0.001 Malignant neoplasm of salivary gland NA BeFree Detail
0.002 Lip and oral cavity carcinoma These results indicated that miR-518c-5p regulates the growth and metastasis of ... BeFree 25536052 Detail
0.002 Lip and oral cavity carcinoma The CXCL12-CXCR4 biological axis consisting of the chemotactic factor CXCL12 and... BeFree 25866764 Detail
<0.001 Metastatic malignant neoplasm to brain NA BeFree Detail
<0.001 Hyperviscosity syndrome NA BeFree Detail
<0.001 Malignant neoplasm of female breast NA BeFree Detail
<0.001 gallbladder carcinoma NA BeFree Detail
0.007 pancreatic carcinoma Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by dere... BeFree 24840182 Detail
0.007 pancreatic carcinoma Furthermore, we show that Nodal promotes pancreatic cancer cell migration and in... BeFree 25557170 Detail
0.007 pancreatic carcinoma Stromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural i... BeFree 25605248 Detail
<0.001 Hereditary pancreatitis NA BeFree Detail
<0.001 desquamative interstitial pneumonia NA BeFree Detail
<0.001 Anaplastic thyroid carcinoma NA BeFree Detail
<0.001 Medullary carcinoma of thyroid NA BeFree Detail
0.003 Papillary thyroid carcinoma The role of both CXCR4 (a chemokine inducing cytoskeletal rearrangement and cell... BeFree 24992171 Detail
0.003 Papillary thyroid carcinoma A previous study demonstrated CXCR4 and nucleolin co-expressed in cell lines, an... BeFree 25326811 Detail
<0.001 Interstitial fibrosis NA BeFree Detail
<0.001 Hepatitis, Autoimmune NA BeFree Detail
0.002 Malignant neoplasm of lung Endogenous CXCR4 protein expression levels varied among the four human lung canc... BeFree 25775124 Detail
0.003 Disease Progression NA LHGDN Detail
<0.001 Sepsis NA BeFree Detail
<0.001 Psoriasiform eczema NA BeFree Detail
<0.001 Epithelial hyperplasia of skin NA BeFree Detail
<0.001 Chronic heart failure NA BeFree Detail
<0.001 Impaired glucose tolerance Semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) analy... BeFree 25303939 Detail
<0.001 Acquired aplastic anemia NA BeFree Detail
0.002 Myelokathexis NA BeFree Detail
<0.001 Coinfection NA BeFree Detail
0.001 Carcinoma breast stage IV Liposomes were modified with anti-CXCR4 antibodies to target metastatic breast c... BeFree 24467226 Detail
<0.001 Malignant neoplasm of stomach stage IV NA BeFree Detail
<0.001 inflammatory breast carcinoma NA BeFree Detail
<0.001 Stage IV Ovarian Carcinoma NA BeFree Detail
<0.001 gastric adenocarcinoma Expression of SNCG, MAP2, SDF-1 and CXCR4 in gastric adenocarcinoma and their cl... BeFree 25400739 Detail
<0.001 Metastatic melanoma Studies ascertaining the potential utility of CXCR4 mRNA as a prognosticator in ... BeFree 25211166 Detail
<0.001 Non-small cell lung cancer metastatic NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus NA BeFree Detail
<0.001 Conventional (Clear Cell) Renal Cell Carcinoma NA BeFree Detail
0.001 Solid tumour NA BeFree Detail
<0.001 Squamous cell carcinoma of the hypopharynx NA BeFree Detail
<0.001 Adenocarcinoma of pancreas NA BeFree Detail
<0.001 intraocular lymphoma NA BeFree Detail
<0.001 Vascular Neoplasms NA BeFree Detail
<0.001 Bone Marrow Neoplasms NA BeFree Detail
0.002 cervix carcinoma ATO inhibited CXCR4-mediated cervical cancer cell invasion in vitro and distant ... BeFree 25047463 Detail
0.002 cervix carcinoma Epigenetic silencing of CXCR4 promotes loss of cell adhesion in cervical cancer. BeFree 25114911 Detail
<0.001 Healing ulcer NA BeFree Detail
<0.001 Tumor necrosis NA BeFree Detail
<0.001 Malignant lymphoma - lymphoplasmacytic MYD88 L265P and CXCR4 mutations in lymphoplasmacytic lymphoma identify cases wit... BeFree 25819228 Detail
<0.001 Stable angina NA BeFree Detail
<0.001 Congenital neutropenia NA BeFree Detail
<0.001 intrahepatic cholangiocarcinoma In conclusion, our result shows that high CXCR4 expression is associated with IH... BeFree 25471741 Detail
<0.001 malignant mesothelioma NA BeFree Detail
<0.001 Growth Hormone-Secreting Pituitary Adenoma NA BeFree Detail
<0.001 Multiple malignancy NA BeFree Detail
<0.001 intestinal cancer NA BeFree Detail
0.008 Malignant neoplasm of pancreas Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by dere... BeFree 24840182 Detail
0.008 Malignant neoplasm of pancreas Furthermore, we show that Nodal promotes pancreatic cancer cell migration and in... BeFree 25557170 Detail
0.008 Malignant neoplasm of pancreas Stromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural i... BeFree 25605248 Detail
<0.001 Secondary malignant neoplasm of prostate NA BeFree Detail
<0.001 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
<0.001 Human immunodeficiency virus, type 2 [HIV-2] infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
0.008 Malignant neoplasm of prostate Autocrine CXCL8-stimulation (i) increased expression of CXCR1 and CXCR2 in PTEN-... BeFree 24970800 Detail
0.008 Malignant neoplasm of prostate Moreover, the prognostic effects of Tpl2 and expressional correlation between Tp... BeFree 25274482 Detail
<0.001 Hematologic Neoplasms Bruton's tyrosine kinase (BTK) and the chemokine receptor CXCR4 are linked in va... BeFree 25083818 Detail
<0.001 Primary immune deficiency disorder NA BeFree Detail
0.450 WHIM syndrome We propose that FLNA interaction with ICL3 is central for endocytosis and signal... BeFree,CLINVAR,CTD_human,MGD,ORPHANET 25355818 Detail
0.450 WHIM syndrome In competitive mouse bone marrow (BM) transplantation experiments, Cxcr4 haploin... BeFree,CLINVAR,CTD_human,MGD,ORPHANET 25662009 Detail
<0.001 endometrial carcinoma NA BeFree Detail
0.004 Secondary malignant neoplasm of liver The expression of six genes was significantly different in primary tumors compar... BeFree 25301403 Detail
0.004 Secondary malignant neoplasm of liver CXCR2, CXCR4, and their chemokine ligands were evaluated in liver metastases of ... BeFree 25580640 Detail
<0.001 dementia NA BeFree Detail
<0.001 Overweight NA BeFree Detail
<0.001 Recurrent tumor The upregulation of CXCR4 by VEGFR inhibitors was dependent on TGFβ/TGFβR, but n... BeFree 25676691 Detail
<0.001 Malignant neoplasm of esophagus Moreover, therapy targeting the CXCL12/CXCR4 axis may open a new direction for t... BeFree 26130416 Detail
<0.001 Thyroid carcinoma NA BeFree Detail
0.001 Ewings sarcoma Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. BeFree 24651452 Detail
0.001 Ewings sarcoma For validation at protein and functional level, the identified isoforms and norm... BeFree 26321665 Detail
<0.001 Malignant glioma NA BeFree Detail
<0.001 Squamous cell carcinoma of mouth NA BeFree Detail
0.003 Osteosarcoma of bone Hypoxia promotes migration and induces CXCR4 expression via HIF-1α activation in... BeFree 24618817 Detail
0.003 Osteosarcoma of bone Our study provides further evidence of the contributions of hypoxia and the HIF-... BeFree 25444927 Detail
0.003 Osteosarcoma of bone Higher CXCR4 mRNA levels were detected in the osteosarcoma cell lines compared t... BeFree 25890096 Detail
<0.001 Aqueous Humor Disorders NA BeFree Detail
0.004 Carcinogenesis Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine re... BeFree 24929539 Detail
0.004 Carcinogenesis The animal experiment was confirmed that silencing of CXCR4 gene by siRNA can ob... BeFree 25149650 Detail
0.004 Carcinogenesis SNCG, MAP2, SDF-1 and CXCR4 may play an important role in the carcinogenesis, pr... BeFree 25400739 Detail
<0.001 Leukemogenesis NA BeFree Detail
0.008 prostate carcinoma Autocrine CXCL8-stimulation (i) increased expression of CXCR1 and CXCR2 in PTEN-... BeFree 24970800 Detail
0.008 prostate carcinoma Moreover, the prognostic effects of Tpl2 and expressional correlation between Tp... BeFree 25274482 Detail
0.002 Epithelial ovarian cancer NA BeFree Detail
<0.001 invasive cancer NA BeFree Detail
<0.001 Refractory cancer CXCR4(WHIM) somatic mutations are common Waldenstrom's Macroglobulinemia (WM), a... BeFree 24912431 Detail
<0.001 Sentinel node (disorder) NA BeFree Detail
0.026 breast carcinoma This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing-... BeFree 24467226 Detail
0.026 breast carcinoma Inhibition of breast cancer metastasis with microRNA-302a by downregulation of C... BeFree 25030358 Detail
0.026 breast carcinoma Targeting the CXCL12-CXCR4/JAK2/STAT3 signaling pathway may be a potential thera... BeFree 25310198 Detail
0.026 breast carcinoma In a panel of LTED cell lines, C-X-C chemokine receptor type 7 (CXCR7) and CXCR4... BeFree 25358600 Detail
0.026 breast carcinoma ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to re... BeFree 25376609 Detail
0.026 breast carcinoma Previously, we and others demonstrated that CXCR4 surface expression is an indep... BeFree 25544759 Detail
0.026 breast carcinoma Finally, we found that ANGPTL2 and CXCR4 expression levels within primary tumor ... BeFree 25773070 Detail
0.026 breast carcinoma Clinical Relevance of Targeting the Gastrin-Releasing Peptide Receptor, Somatost... BeFree 26251419 Detail
0.010 Primary myelofibrosis Abnormal expression of HMGA2 and CXCR4 in IM granulocytes was dependent on the p... BeFree 16990584 Detail
0.002 Carcinoma of lung Endogenous CXCR4 protein expression levels varied among the four human lung canc... BeFree 25775124 Detail
<0.001 Malignant neoplasm of gastrointestinal tract NA BeFree Detail
0.008 Secondary malignant neoplasm of lymph node We reduced the cell surface level of CXCR4 and called the technique intracellula... BeFree 25866764 Detail
0.004 colon carcinoma The expression of chemokine receptors CXCR3 and CXCR4 in predicting postoperativ... BeFree 25232565 Detail
0.004 colon carcinoma Platelet activation with a PAR1 agonist triggered TGF-β secretion, which induced... BeFree 25846512 Detail
0.004 colon carcinoma Targeted therapy utilizing the CXCR4/CXCL12 axis could be an effective strategy ... BeFree 25960214 Detail
0.004 stomach carcinoma Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine re... BeFree 24929539 Detail
0.002 Carcinoma of bladder NA BeFree Detail
<0.001 airway disease NA BeFree Detail
0.003 Central neuroblastoma The present study indicates that the inflammatory cytokine, TNF-α, partially fun... BeFree 25503960 Detail
0.003 Central neuroblastoma Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and ind... BeFree 25774696 Detail
0.003 Central neuroblastoma Finally, coexpression of CXCR4 and CXCR7 receptors significantly and selectively... BeFree 25955316 Detail
0.002 Malignant neoplasm of kidney CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells. BeFree 24991762 Detail
<0.001 Chronic neutropenia NA BeFree Detail
<0.001 Idiopathic Inflammatory Myopathies NA BeFree Detail
<0.001 malignant pleural mesothelioma NA BeFree Detail
<0.001 thrombocytosis NA BeFree Detail
<0.001 Immunodeficiency congenital Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a... BeFree 25355818 Detail
<0.001 Invasive breast carcinoma NA BeFree Detail
<0.001 Rhabdoid Tumor of the Kidney NA BeFree Detail
<0.001 Infectious disease of lung NA BeFree Detail
<0.001 Cerebral Ischemia NA BeFree Detail
<0.001 Renal cancer metastatic NA BeFree Detail
<0.001 cancer recurrence NA BeFree Detail
<0.001 Metastatic Prostate Carcinoma NA BeFree Detail
<0.001 Primary infection NOS NA BeFree Detail
<0.001 Ovarian adenocarcinoma NA BeFree Detail
<0.001 Invasive Ductal Breast Carcinoma NA BeFree Detail
0.005 Malignant neoplasm of ovary Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA i... BeFree 25149650 Detail
0.002 HIV disease progression NA GAD Detail
<0.001 endometrial adenocarcinoma NA BeFree Detail
0.002 Squamous cell carcinoma of the head and neck CXCL12 and CXCR4, but not CXCR7, are primarily expressed by the stroma in head a... BeFree 25474514 Detail
0.002 Squamous cell carcinoma of the head and neck Construction of a CXCL12-KDEL fusion gene to inhibit head and neck squamous cell... BeFree 25866764 Detail
<0.001 Ductal Carcinoma NA BeFree Detail
<0.001 Mammary Carcinoma, Human NA BeFree Detail
<0.001 Myxoid cyst NA BeFree Detail
<0.001 Morphologically altered structure NA BeFree Detail
0.004 sarcoma NA BeFree,LHGDN Detail
<0.001 Lymphocytic infiltration NA BeFree Detail
<0.001 Precursor B-cell lymphoblastic leukemia These findings demonstrate, for the first time, that CD9 plays a key role in the... BeFree 26320102 Detail
<0.001 Chronic myeloproliferative disorder NA BeFree Detail
<0.001 Pancreatic intraepithelial neoplasia NA BeFree Detail
<0.001 Precursor T cell lymphoblastic leukemia/lymphoblastic lymphoma NA BeFree Detail
<0.001 Atypical Ductal Breast Hyperplasia NA BeFree Detail
<0.001 Gastric Mucosa-Associated Lymphoid Tissue Lymphoma NA BeFree Detail
<0.001 Invasive Carcinoma NA BeFree Detail
<0.001 Neuroblastic Tumor In NB, CXCR4 expression was shown to be associated to highly aggressive undiffer... BeFree 25955316 Detail
<0.001 Conventional Chondrosarcoma NA BeFree Detail
<0.001 Mucoepidermoid carcinoma of salivary gland NA BeFree Detail
<0.001 Sporadic Breast Carcinoma NA BeFree Detail
<0.001 differentiated thyroid gland carcinoma Well-differentiated thyroid cancer with a minor poorly differentiated component:... BeFree 24992171 Detail
0.002 renal carcinoma CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells. BeFree 24991762 Detail
<0.001 Cardiomyopathy, Familial Idiopathic NA BeFree Detail
0.041 Mammary Neoplasms Thus, understanding how CXCR4 expression is regulated in breast cancer cells cou... BeFree,LHGDN 25773070 Detail
<0.001 Hereditary Melanoma NA BeFree Detail
<0.001 Neuropathogenesis NA BeFree Detail
<0.001 Tumor Angiogenesis NA BeFree Detail
<0.001 Tumor Expansion NA BeFree Detail
0.002 Xenograft Model Herein we demonstrate that the chemokine receptor CXCR4 is essential to the LIC ... BeFree 26058076 Detail
0.010 colorectal cancer SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colore... BeFree,GAD 25150783 Detail
0.010 colorectal cancer Treatment of CRC cells with the CXCR4 antagonist AMD3100 attenuated SEMA3F knock... BeFree,GAD 25866254 Detail
<0.001 Pneumocystis jiroveci pneumonia NA BeFree Detail
0.001 Non-Malignant Ascites Adverse Event NA BeFree Detail
<0.001 Chronic Kidney Diseases NA BeFree Detail
<0.001 Adenocarcinoma, Endometrioid NA BeFree Detail
<0.001 Glioblastoma multiforme NA BeFree Detail
<0.001 tumor vasculature TAMs were the predominant cells expressing immunoreactive CXCR4 in chemotherapy-... BeFree 26269531 Detail
<0.001 Secondary Focal Segmental Glomerulosclerosis NA BeFree Detail
<0.001 Painful Bladder Syndrome NA BeFree Detail
<0.001 Meningioma, benign, no ICD-O subtype NA BeFree Detail
0.001 Idiopathic Pulmonary Fibrosis The clinical relevance of these data was confirmed by strong CXCR4 expression in... BeFree 25103869 Detail
<0.001 Recurrent infections (sinusitis and bacterial pneumonia and meningitis) NA BeFree Detail
<0.001 severe congenital neutropenia NA BeFree Detail
<0.001 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma Loss of CXCR4 targeted key T-ALL regulators, including the MYC pathway, and decr... BeFree 26058075 Detail
<0.001 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphobl... BeFree 26058076 Detail
0.007 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree,LHGDN Detail
0.009 liver carcinoma Together, these data suggest that CD90+CXCR4+ HCC cells may be CTSCs and selecti... BeFree,GAD,LHGDN 25672610 Detail
<0.001 Allergic rhinitis (disorder) NA BeFree Detail
<0.001 Combined immunodeficiency disease NA BeFree Detail
0.001 Nasopharyngeal carcinoma NA BeFree Detail
<0.001 Clear-cell metastatic renal cell carcinoma NA BeFree Detail
<0.001 Pulmonary arterial hypertension NA BeFree Detail
<0.001 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) NA BeFree Detail
<0.001 Micropapillary carcinoma NA BeFree Detail
0.120 Juvenile arthritis NA CTD_human Detail
0.001 Triple Negative Breast Neoplasms During co-culture CXCR4 protein expression of TNBC cell lines HCC1806 and HCC193... BeFree 25420519 Detail
0.001 Triple Negative Breast Neoplasms Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin. BeFree 25544759 Detail
0.014 Infection NA LHGDN Detail
<0.001 Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia NA BeFree Detail
<0.001 Experimental Organism Basal Cell Carcinoma NA BeFree Detail
<0.001 Cytogenetically normal acute myeloid leukemia NA BeFree Detail
0.003 acquired immunodeficiency syndrome NA BeFree,LHGDN Detail
0.006 adenocarcinoma NA BeFree,LHGDN Detail
<0.001 adenoma NA BeFree Detail
0.010 Primary myelofibrosis This trafficking pattern could not be attributed to discordant expression of int... BeFree,LHGDN 25461253 Detail
0.003 AIDS Dementia Complex NA BeFree,LHGDN Detail
<0.001 Alzheimer's disease NA BeFree Detail
<0.001 aplastic anemia CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltratio... BeFree 25647836 Detail
<0.001 Angina, Unstable NA BeFree Detail
0.003 Anoxia NA LHGDN Detail
<0.001 arteriosclerosis CXCR4 blockade induces atherosclerosis by affecting neutrophil function. BeFree 24816217 Detail
0.004 arthritis NA BeFree,LHGDN Detail
0.125 rheumatoid arthritis Although chemokine stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 ... BeFree,CTD_human,LHGDN 24516346 Detail
0.005 asthma The CXCR4/CXCL12 axis contributes to chemotaxis of fibrocytes in patients in the... BeFree,GAD 25441632 Detail
0.002 Astrocytoma NA BeFree Detail
<0.001 atherosclerosis CXCR4 blockade induces atherosclerosis by affecting neutrophil function. BeFree 24816217 Detail
<0.001 Autoimmune Diseases The chemokine CXCL12 and its G protein-coupled receptors CXCR4 and ACKR3 are imp... BeFree 26216880 Detail
<0.001 Bacterial Infections NA BeFree Detail
<0.001 bipolar disorder Treatment of the CXCR4(+) NPCs with a pharmacological inhibitor of glycogen synt... BeFree 25733313 Detail
0.002 Malignant neoplasm of urinary bladder NA BeFree Detail
0.003 Bladder Neoplasm NA BeFree,LHGDN Detail
<0.001 Blast Phase NA BeFree Detail
<0.001 Bone Diseases NA BeFree Detail
<0.001 Bone neoplasms NA BeFree Detail
<0.001 Brain Diseases NA BeFree Detail
0.005 Brain Neoplasms The role of CXCL12 and CXCR4 in the development of brain tumors requires further... BeFree,LHGDN 24934367 Detail
0.005 Brain Neoplasms Differential expression of CXCR4 and CXCR7 in brain tumors derived cells compare... BeFree,LHGDN 25227814 Detail
0.029 Malignant neoplasm of breast This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing-... BeFree,GAD 24467226 Detail
0.029 Malignant neoplasm of breast Inhibition of breast cancer metastasis with microRNA-302a by downregulation of C... BeFree,GAD 25030358 Detail
0.029 Malignant neoplasm of breast Targeting the CXCL12-CXCR4/JAK2/STAT3 signaling pathway may be a potential thera... BeFree,GAD 25310198 Detail
0.029 Malignant neoplasm of breast In a panel of LTED cell lines, C-X-C chemokine receptor type 7 (CXCR7) and CXCR4... BeFree,GAD 25358600 Detail
0.029 Malignant neoplasm of breast ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to re... BeFree,GAD 25376609 Detail
0.029 Malignant neoplasm of breast Previously, we and others demonstrated that CXCR4 surface expression is an indep... BeFree,GAD 25544759 Detail
0.029 Malignant neoplasm of breast Finally, we found that ANGPTL2 and CXCR4 expression levels within primary tumor ... BeFree,GAD 25773070 Detail
0.029 Malignant neoplasm of breast Clinical Relevance of Targeting the Gastrin-Releasing Peptide Receptor, Somatost... BeFree,GAD 26251419 Detail
<0.001 Breast Diseases NA BeFree Detail
<0.001 bronchiolitis obliterans NA BeFree Detail
0.004 Malignant tumor of colon The expression of chemokine receptors CXCR3 and CXCR4 in predicting postoperativ... BeFree 25232565 Detail
0.004 Malignant tumor of colon Platelet activation with a PAR1 agonist triggered TGF-β secretion, which induced... BeFree 25846512 Detail
0.004 Malignant tumor of colon Targeted therapy utilizing the CXCR4/CXCL12 axis could be an effective strategy ... BeFree 25960214 Detail
<0.001 female breast carcinoma NA BeFree Detail
<0.001 Rectal Carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
0.003 Noninfiltrating Intraductal Carcinoma NA BeFree,LHGDN Detail
0.003 Non-small cell lung carcinoma Here, we show that CD133(+)/CXCR4(+) cancer-initiating cells (CIC) directly isol... BeFree 26141860 Detail
0.003 renal cell carcinoma HIF2α is involved in the expansion of CXCR4-positive cancer stem-like cells in r... BeFree 26439684 Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
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ATO inhibited CXCR4-mediated cervical cancer cell invasion in vitro and distant metastasis in vivo. DisGeNET Detail
Epigenetic silencing of CXCR4 promotes loss of cell adhesion in cervical cancer. DisGeNET Detail
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The association of CXCR4 expression with prognosis and clinicopathological indicators in colorectal ... DisGeNET Detail
SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colorectal cancer by activ... DisGeNET Detail
Treatment of CRC cells with the CXCR4 antagonist AMD3100 attenuated SEMA3F knockdown-induced invasio... DisGeNET Detail
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High expression levels of CXCL12 and CXCR4 predict recurrence of adamanti-nomatous craniopharyngioma... DisGeNET Detail
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These observations demonstrate a potentially reno-protective role for CXCR4 in diabetes that is impe... DisGeNET Detail
These observations demonstrate a potentially reno-protective role for CXCR4 in diabetes that is impe... DisGeNET Detail
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Although CXCR4 expression was also increased in biopsy tissue from patients with diabetic nephropath... DisGeNET Detail
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Moreover, therapy targeting the CXCL12/CXCR4 axis may open a new direction for treatment of EC patie... DisGeNET Detail
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VEGFR inhibitors upregulate CXCR4 in VEGF receptor-expressing glioblastoma in a TGFβR signaling-depe... DisGeNET Detail
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Increased CXCR4 use of HIV-1 subtype C identified by population sequencing in patients failing antir... DisGeNET Detail
The CX3CR1 A allele and lower genetic scores may restrict the switch of HIV-1 tropism from R5 to X4. DisGeNET Detail
CXCR4 usage can emerge independently, in multiple lineages, along the course of HIV infection.The mo... DisGeNET Detail
When pDC were depleted prior to HIV-1 infection, the induction of IFN-I and interferon-stimulated ge... DisGeNET Detail
Furthermore, a mutated virus that is capable of using both CCR5 and CXCR4 as entry coreceptor is spe... DisGeNET Detail
Our study demonstrates that individuals may be infected by minority X4 viruses from a population tha... DisGeNET Detail
The interaction of HIV-1 and target cells involves sequential binding of the viral gp120 Env protein... DisGeNET Detail
Chemokine receptors CXCR4 and CCR5 are indispensable co-receptors for HIV-1 entry into host cells. DisGeNET Detail
HIV-1 Nef downregulates the viral entry receptor CD4 as well as the coreceptors CCR5 and CXCR4 from ... DisGeNET Detail
Treatment failure with drug-resistant virus is particularly interesting because it tends to be rare,... DisGeNET Detail
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There is marked evidence that the SDF-1/CXCR4 axis is involved in the pathogenesis of leukemia and t... DisGeNET Detail
CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia. DisGeNET Detail
It has previously been shown that SDF1/CXCR4-induced migration is dependent on activation of downstr... DisGeNET Detail
Circulating chronic lymphocytic leukemia (CLL) cells display an abnormal increase in the surface lev... DisGeNET Detail
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CXCR4 expression accounts for clinical phenotype and outcome in acute myeloid leukemia. DisGeNET Detail
The N-terminal CEBPA mutant in acute myeloid leukemia impairs CXCR4 expression. DisGeNET Detail
Ibrutinib inhibits SDF1/CXCR4 mediated migration in AML. DisGeNET Detail
A designed peptide targeting CXCR4 displays anti-acute myelocytic leukemia activity in vitro and in ... DisGeNET Detail
Patients with defective NK cells showed a profound gene expression decrease in AML blasts for cytoki... DisGeNET Detail
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Role of the hybrid Bcr/Abl kinase in the pathogenesis of chronic myeloid leukemia lacking C-Abl and ... DisGeNET Detail
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Immunophenotypic analysis of lung tumor cells intravenously injected or spontaneously disseminated t... DisGeNET Detail
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Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine receptor 4 (CXCR4) is ... DisGeNET Detail
These results demonstrate crosstalk among WIP1, CXCR4 and GRK5, which may be important for the aggre... DisGeNET Detail
Role of CXCL12 and CXCR4 in normal cerebellar development and medulloblastoma. DisGeNET Detail
Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with established histopat... DisGeNET Detail
Deregulation of the CXCR4/CXCL12 axis was reported in melanoma tumorigenesis while also linked to BR... DisGeNET Detail
PAX3 and FOXD3 Promote CXCR4 Expression in Melanoma. DisGeNET Detail
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In 176 paired clinical samples, BTK and CXCR4 expression was lower in myeloma cells purified from a ... DisGeNET Detail
It has previously been shown that SDF1/CXCR4-induced migration is dependent on activation of downstr... DisGeNET Detail
Several chemokines/chemokine receptors such as CXCL12, CCL3, CXCR4 and CCR1 attract multiple myeloma... DisGeNET Detail
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This trafficking pattern could not be attributed to discordant expression of integrins or chemokine ... DisGeNET Detail
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In addition, a significant association was revealed between positive CXCR4 expression and age (less ... DisGeNET Detail
Because breast cancer patient survival inversely correlates with metastasis, we engineered vehicles ... DisGeNET Detail
Furthermore, coexpression of HIF-1α and CXCR4 was significantly higher in patients with distant meta... DisGeNET Detail
This study reveals the highly plastic and dynamic nature of CXCR4 expression in Ewing sarcoma and su... DisGeNET Detail
Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by deregulating the express... DisGeNET Detail
Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine receptor 4 (CXCR4) is ... DisGeNET Detail
The role of both CXCR4 (a chemokine inducing cytoskeletal rearrangement and cell adhesion) and BRAF ... DisGeNET Detail
More promisingly, miR-302a inhibited the invasion and metastasis of breast cancer cells in vitro and... DisGeNET Detail
Arsenic trioxide inhibits CXCR4-mediated metastasis by interfering miR-520h/PP2A/NF-κB signaling in ... DisGeNET Detail
These findings demonstrate the first evidence that epigenetic silencing of CXCR4 makes the cells ine... DisGeNET Detail
CXCR7 was not detectable in secondary tumors but CXCR4 was expressed. DisGeNET Detail
CXCR4 is a marker of poor prognosis in various neoplasms, correlating with metastatic disease and de... DisGeNET Detail
The subsequent increase in circulating granulocyte number, with an increase in serum CXCL12 and gran... DisGeNET Detail
The chemokine receptor CXCR4 and signal transducer and activator of transcription 3 (STAT3) play an ... DisGeNET Detail
Our findings suggest that ΔNP63α regulation of CXCR4 may have strong implications in the regulation ... DisGeNET Detail
SNCG, MAP2, SDF-1 and CXCR4 may play an important role in the carcinogenesis, progression, invasion ... DisGeNET Detail
The HIF-1α/CXCR4 pathway supports hypoxia-induced metastasis of human osteosarcoma cells. DisGeNET Detail
In conclusion, our result shows that high CXCR4 expression is associated with IHCC progression and m... DisGeNET Detail
The present study indicates that the inflammatory cytokine, TNF-α, partially functions through the N... DisGeNET Detail
Downregulation of CXCR4 by SDF-KDEL in SBC-5 cells inhibits their migration in vitro and organ metas... DisGeNET Detail
These results indicated that miR-518c-5p regulates the growth and metastasis of oral cancer as a dow... DisGeNET Detail
Finally, IL-24 when combined with CXCR4 inhibitors (AMD3100, SJA5) or with CXCR4 siRNA demonstrated ... DisGeNET Detail
Treatment of CRC cells with the CXCR4 antagonist AMD3100 attenuated SEMA3F knockdown-induced invasio... DisGeNET Detail
High expression of CXCR4 may help oral squamous cancer cells invade local tissues and metastasize to... DisGeNET Detail
Recent evidence suggests that CXCR4-mediated proliferation and metastasis of tumor cells is regulate... DisGeNET Detail
Downregulation of the CXCR4/CXCL12 axis thus reduces cancer growth and metastasis. DisGeNET Detail
Here, we show that CD133(+)/CXCR4(+) cancer-initiating cells (CIC) directly isolated from patient-de... DisGeNET Detail
The chemokine receptor CXCR4 is active in melanoma metastasis, although the mechanism for the promot... DisGeNET Detail
Chemokine receptor CXCR4 is involved in tumor growth, angiogenesis and metastasis. DisGeNET Detail
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The present study indicates that the inflammatory cytokine, TNF-α, partially functions through the N... DisGeNET Detail
Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in ... DisGeNET Detail
Finally, coexpression of CXCR4 and CXCR7 receptors significantly and selectively increased NB dissem... DisGeNET Detail
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Although chemokine stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 induce degradation o... DisGeNET Detail
Hypoxia promotes migration and induces CXCR4 expression via HIF-1α activation in human osteosarcoma. DisGeNET Detail
Our study provides further evidence of the contributions of hypoxia and the HIF-1α/CXCR4 pathway to ... DisGeNET Detail
Higher CXCR4 mRNA levels were detected in the osteosarcoma cell lines compared to BMSCs. DisGeNET Detail
Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA in nude mice model of... DisGeNET Detail
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This two-layered microfluidic system provides a feasible platform for perfusion culture, and was use... DisGeNET Detail
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Here we show that, in the LNCaP prostate-tumor cell line, androgens coordinate the expression of CXC... DisGeNET Detail
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HIV-1 Nef downregulates the viral entry receptor CD4 as well as the coreceptors CCR5 and CXCR4 from ... DisGeNET Detail
Prognostic and predictive role of CXCR4, IGF-1R and Ezrin expression in localized synovial sarcoma: ... DisGeNET Detail
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CXCR4 expression enhances diffuse large B cell lymphoma dissemination and decreases patient survival... DisGeNET Detail
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Importantly, our results demonstrate that BZ inhibits expression of the chemokine receptor CXCR4 in ... DisGeNET Detail
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Thus, CXCR4 may prove to be a promising target for the prevention and effective treatment of metasta... DisGeNET Detail
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Correlation of chemokine receptor CXCR4 mRNA in primary cutaneous melanoma with established histopat... DisGeNET Detail
Moreover, therapy targeting the CXCL12/CXCR4 axis may open a new direction for treatment of EC patie... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
These results indicated that miR-518c-5p regulates the growth and metastasis of oral cancer as a dow... DisGeNET Detail
The CXCL12-CXCR4 biological axis consisting of the chemotactic factor CXCL12 and its specific recept... DisGeNET Detail
This study reveals the highly plastic and dynamic nature of CXCR4 expression in Ewing sarcoma and su... DisGeNET Detail
The mechanism of pulmonary metastasis inhibition involved decreased expression of CXC chemokine rece... DisGeNET Detail
Importantly, we show that knockdown of either CXCR4 or MIF abrogates MSC homing to tumors in an in v... DisGeNET Detail
Additionally, IL-24, when combined with CXCR4 inhibitors exhibited enhanced anti-metastatic activity... DisGeNET Detail
In in vivo experiments, the knockout of CXCR4 suppressed the development of metastastic lesions in t... DisGeNET Detail
We compared the expression levels of C-X-C chemokine receptor type 4 (CXCR4) in the human small cell... DisGeNET Detail
In addition, we used a xenograft mouse model established by intracardiac injection of tumor cells to... DisGeNET Detail
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CXCL12/CXCR4 and CCL19/CCR7 enhanced fibrocyte transmigration in the Asthma AE group and in patients... DisGeNET Detail
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The role of both CXCR4 (a chemokine inducing cytoskeletal rearrangement and cell adhesion) and BRAF ... DisGeNET Detail
In the network of chemokine signaling pathways, recent reports have described the SDF-1α/CXCR4 axis ... DisGeNET Detail
Stromal cell-derived factor 1 (SDF-1) and its receptor, CXCR4, play an important role in angiogenesi... DisGeNET Detail
The expression of chemokine receptors CXCR3 and CXCR4 in predicting postoperative tumour progression... DisGeNET Detail
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These results indicated that miR-518c-5p regulates the growth and metastasis of oral cancer as a dow... DisGeNET Detail
The CXCL12-CXCR4 biological axis consisting of the chemotactic factor CXCL12 and its specific recept... DisGeNET Detail
NA DisGeNET Detail
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Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by deregulating the express... DisGeNET Detail
Furthermore, we show that Nodal promotes pancreatic cancer cell migration and invasion, induces epit... DisGeNET Detail
Stromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural invasion in pancreati... DisGeNET Detail
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The role of both CXCR4 (a chemokine inducing cytoskeletal rearrangement and cell adhesion) and BRAF ... DisGeNET Detail
A previous study demonstrated CXCR4 and nucleolin co-expressed in cell lines, and the present study ... DisGeNET Detail
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Endogenous CXCR4 protein expression levels varied among the four human lung cancer cell lines. DisGeNET Detail
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Semi-quantitative reverse transcription polymerase chain reaction (RT-PCR) analysis revealed decreas... DisGeNET Detail
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Liposomes were modified with anti-CXCR4 antibodies to target metastatic breast cancer (MBC) cells an... DisGeNET Detail
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Expression of SNCG, MAP2, SDF-1 and CXCR4 in gastric adenocarcinoma and their clinical significance. DisGeNET Detail
Studies ascertaining the potential utility of CXCR4 mRNA as a prognosticator in melanoma have focuse... DisGeNET Detail
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ATO inhibited CXCR4-mediated cervical cancer cell invasion in vitro and distant metastasis in vivo. DisGeNET Detail
Epigenetic silencing of CXCR4 promotes loss of cell adhesion in cervical cancer. DisGeNET Detail
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MYD88 L265P and CXCR4 mutations in lymphoplasmacytic lymphoma identify cases with high disease activ... DisGeNET Detail
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In conclusion, our result shows that high CXCR4 expression is associated with IHCC progression and m... DisGeNET Detail
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Ran GTPase protein promotes metastasis and invasion in pancreatic cancer by deregulating the express... DisGeNET Detail
Furthermore, we show that Nodal promotes pancreatic cancer cell migration and invasion, induces epit... DisGeNET Detail
Stromal-derived factor-1α/CXCL12-CXCR4 chemotactic pathway promotes perineural invasion in pancreati... DisGeNET Detail
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Autocrine CXCL8-stimulation (i) increased expression of CXCR1 and CXCR2 in PTEN-deficient CaP cells ... DisGeNET Detail
Moreover, the prognostic effects of Tpl2 and expressional correlation between Tpl2 and EMT-related m... DisGeNET Detail
Bruton's tyrosine kinase (BTK) and the chemokine receptor CXCR4 are linked in various hematologic ma... DisGeNET Detail
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We propose that FLNA interaction with ICL3 is central for endocytosis and signaling of WT and WHIM-l... DisGeNET Detail
In competitive mouse bone marrow (BM) transplantation experiments, Cxcr4 haploinsufficiency was suff... DisGeNET Detail
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The expression of six genes was significantly different in primary tumors compared with their matche... DisGeNET Detail
CXCR2, CXCR4, and their chemokine ligands were evaluated in liver metastases of colorectal cancer in... DisGeNET Detail
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The upregulation of CXCR4 by VEGFR inhibitors was dependent on TGFβ/TGFβR, but not HGF/MET, signalin... DisGeNET Detail
Moreover, therapy targeting the CXCL12/CXCR4 axis may open a new direction for treatment of EC patie... DisGeNET Detail
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Stress-induced CXCR4 promotes migration and invasion of ewing sarcoma. DisGeNET Detail
For validation at protein and functional level, the identified isoforms and normal CXCR4 were cloned... DisGeNET Detail
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Hypoxia promotes migration and induces CXCR4 expression via HIF-1α activation in human osteosarcoma. DisGeNET Detail
Our study provides further evidence of the contributions of hypoxia and the HIF-1α/CXCR4 pathway to ... DisGeNET Detail
Higher CXCR4 mRNA levels were detected in the osteosarcoma cell lines compared to BMSCs. DisGeNET Detail
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Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine receptor 4 (CXCR4) is ... DisGeNET Detail
The animal experiment was confirmed that silencing of CXCR4 gene by siRNA can obviously inhibit the ... DisGeNET Detail
SNCG, MAP2, SDF-1 and CXCR4 may play an important role in the carcinogenesis, progression, invasion ... DisGeNET Detail
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Autocrine CXCL8-stimulation (i) increased expression of CXCR1 and CXCR2 in PTEN-deficient CaP cells ... DisGeNET Detail
Moreover, the prognostic effects of Tpl2 and expressional correlation between Tpl2 and EMT-related m... DisGeNET Detail
NA DisGeNET Detail
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CXCR4(WHIM) somatic mutations are common Waldenstrom's Macroglobulinemia (WM), and are associated wi... DisGeNET Detail
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This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing--significantly reduc... DisGeNET Detail
Inhibition of breast cancer metastasis with microRNA-302a by downregulation of CXCR4 expression. DisGeNET Detail
Targeting the CXCL12-CXCR4/JAK2/STAT3 signaling pathway may be a potential therapeutic strategy for ... DisGeNET Detail
In a panel of LTED cell lines, C-X-C chemokine receptor type 7 (CXCR7) and CXCR4 were upregulated co... DisGeNET Detail
ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to regulate breast cancer... DisGeNET Detail
Previously, we and others demonstrated that CXCR4 surface expression is an independent prognostic fa... DisGeNET Detail
Finally, we found that ANGPTL2 and CXCR4 expression levels within primary tumor tissues from breast ... DisGeNET Detail
Clinical Relevance of Targeting the Gastrin-Releasing Peptide Receptor, Somatostatin Receptor 2, or ... DisGeNET Detail
Abnormal expression of HMGA2 and CXCR4 in IM granulocytes was dependent on the presence and the muta... DisGeNET Detail
Endogenous CXCR4 protein expression levels varied among the four human lung cancer cell lines. DisGeNET Detail
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We reduced the cell surface level of CXCR4 and called the technique intracellular sequestration. By ... DisGeNET Detail
The expression of chemokine receptors CXCR3 and CXCR4 in predicting postoperative tumour progression... DisGeNET Detail
Platelet activation with a PAR1 agonist triggered TGF-β secretion, which induced EMT of SW620 human ... DisGeNET Detail
Targeted therapy utilizing the CXCR4/CXCL12 axis could be an effective strategy for treatment of col... DisGeNET Detail
Stromal cell-derived factor-1 (SDF-1) (CXC chemokine ligand-12)/CXC chemokine receptor 4 (CXCR4) is ... DisGeNET Detail
NA DisGeNET Detail
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The present study indicates that the inflammatory cytokine, TNF-α, partially functions through the N... DisGeNET Detail
Mesenchymal stromal cell secretome up-regulates 47 kDa CXCR4 expression, and induce invasiveness in ... DisGeNET Detail
Finally, coexpression of CXCR4 and CXCR7 receptors significantly and selectively increased NB dissem... DisGeNET Detail
CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells. DisGeNET Detail
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Warts, hypogammaglobulinemia, infections, and myelokathexis (WHIM) syndrome is a rare congenital imm... DisGeNET Detail
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Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA in nude mice model of... DisGeNET Detail
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CXCL12 and CXCR4, but not CXCR7, are primarily expressed by the stroma in head and neck squamous cel... DisGeNET Detail
Construction of a CXCL12-KDEL fusion gene to inhibit head and neck squamous cell carcinoma metastasi... DisGeNET Detail
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These findings demonstrate, for the first time, that CD9 plays a key role in the CXCR4-mediated migr... DisGeNET Detail
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In NB, CXCR4 expression was shown to be associated to highly aggressive undifferentiated tumors, whi... DisGeNET Detail
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Well-differentiated thyroid cancer with a minor poorly differentiated component: clonal heterogeneit... DisGeNET Detail
CXCR4 and CXCR7 transduce through mTOR in human renal cancer cells. DisGeNET Detail
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Thus, understanding how CXCR4 expression is regulated in breast cancer cells could suggest approache... DisGeNET Detail
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Herein we demonstrate that the chemokine receptor CXCR4 is essential to the LIC activity of T-ALL le... DisGeNET Detail
SDF-1/CXCR4 promotes epithelial-mesenchymal transition and progression of colorectal cancer by activ... DisGeNET Detail
Treatment of CRC cells with the CXCR4 antagonist AMD3100 attenuated SEMA3F knockdown-induced invasio... DisGeNET Detail
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TAMs were the predominant cells expressing immunoreactive CXCR4 in chemotherapy-treated mouse tumors... DisGeNET Detail
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The clinical relevance of these data was confirmed by strong CXCR4 expression in vessels close to fi... DisGeNET Detail
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Loss of CXCR4 targeted key T-ALL regulators, including the MYC pathway, and decreased leukemia initi... DisGeNET Detail
CXCR4 Is Required for Leukemia-Initiating Cell Activity in T Cell Acute Lymphoblastic Leukemia. DisGeNET Detail
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Together, these data suggest that CD90+CXCR4+ HCC cells may be CTSCs and selective elimination of th... DisGeNET Detail
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During co-culture CXCR4 protein expression of TNBC cell lines HCC1806 and HCC1937 was significantly ... DisGeNET Detail
Silencing of CXCR4 sensitizes triple-negative breast cancer cells to cisplatin. DisGeNET Detail
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This trafficking pattern could not be attributed to discordant expression of integrins or chemokine ... DisGeNET Detail
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CXCR4 expression on pathogenic T cells facilitates their bone marrow infiltration in a mouse model o... DisGeNET Detail
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CXCR4 blockade induces atherosclerosis by affecting neutrophil function. DisGeNET Detail
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Although chemokine stromal cell-derived factor 1 (SDF-1) and its receptor CXCR4 induce degradation o... DisGeNET Detail
The CXCR4/CXCL12 axis contributes to chemotaxis of fibrocytes in patients in the Asthma AE group, wh... DisGeNET Detail
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CXCR4 blockade induces atherosclerosis by affecting neutrophil function. DisGeNET Detail
The chemokine CXCL12 and its G protein-coupled receptors CXCR4 and ACKR3 are implicated in cancer an... DisGeNET Detail
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Treatment of the CXCR4(+) NPCs with a pharmacological inhibitor of glycogen synthase kinase 3, a kno... DisGeNET Detail
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The role of CXCL12 and CXCR4 in the development of brain tumors requires further research. DisGeNET Detail
Differential expression of CXCR4 and CXCR7 in brain tumors derived cells compared to non-tumoral sam... DisGeNET Detail
This synergistic approach--coupling the CXCR4 axis blockade with Lcn2 silencing--significantly reduc... DisGeNET Detail
Inhibition of breast cancer metastasis with microRNA-302a by downregulation of CXCR4 expression. DisGeNET Detail
Targeting the CXCL12-CXCR4/JAK2/STAT3 signaling pathway may be a potential therapeutic strategy for ... DisGeNET Detail
In a panel of LTED cell lines, C-X-C chemokine receptor type 7 (CXCR7) and CXCR4 were upregulated co... DisGeNET Detail
ΔNP63α transcriptionally activates chemokine receptor 4 (CXCR4) expression to regulate breast cancer... DisGeNET Detail
Previously, we and others demonstrated that CXCR4 surface expression is an independent prognostic fa... DisGeNET Detail
Finally, we found that ANGPTL2 and CXCR4 expression levels within primary tumor tissues from breast ... DisGeNET Detail
Clinical Relevance of Targeting the Gastrin-Releasing Peptide Receptor, Somatostatin Receptor 2, or ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The expression of chemokine receptors CXCR3 and CXCR4 in predicting postoperative tumour progression... DisGeNET Detail
Platelet activation with a PAR1 agonist triggered TGF-β secretion, which induced EMT of SW620 human ... DisGeNET Detail
Targeted therapy utilizing the CXCR4/CXCL12 axis could be an effective strategy for treatment of col... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Here, we show that CD133(+)/CXCR4(+) cancer-initiating cells (CIC) directly isolated from patient-de... DisGeNET Detail
HIF2α is involved in the expansion of CXCR4-positive cancer stem-like cells in renal cell carcinoma. DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386626619 dbSNP
Genome
hg38
Position
chr2:136,114,349-136,119,177
Variant Type
snv
Genome browser