Annotation Detail

Information
Associated Genes
CXCR4
Associated Variants
CXCR4 MUTATION
CXCR4 MUTATION
Associated Disease
HIV Infections
Source Database
DisGeNET
Description
Treatment failure with drug-resistant virus is particularly interesting because it tends to be rare, with lack of sensitivity usually associated with the presence of CXCR4-using virus (CXCR4 is the main alternative coreceptor HIV-1 uses, in addition to CD4).
Pubmed
26339063
Section of the abstract supporting the evidence
IMPORTANCE
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0949168283993425
Drugs