congenital heart disease

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Information
Disease name
congenital heart disease
Disease ID
DOID:1682
Description
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
HYAL2 3 50,317,790 50,322,782 8
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT02979587 Active, not recruiting N/A The Medtronic Harmony™ Transcatheter Pulmonary Valve Clinical Study January 2017 February 2031
NCT02892136 Active, not recruiting Technical Development for Pediatric Cardiovascular MRI May 2013 December 2026
NCT04271358 Active, not recruiting N/A Peer Coaching Intervention in Young Adults With Congenital Heart Disease October 8, 2020 March 2, 2032
NCT02492269 Active, not recruiting Phase 2 Stress Response and Neurodevelopmental Outcome After Cardiac Surgery Utilizing CPB in Children: A Prospective, Double Blinded and Randomized Study May 2014 December 2025
NCT04769167 Active, not recruiting N/A Congenital Heart Anomaly Risk in Maternal Enteroviral Infection and Diabetes February 1, 2021 December 2027
NCT06031831 Active, not recruiting Analysis of Risk Factors and Prognosis of Pediatric Patients After Operations for Congenital Heart Disease May 15, 2022 December 31, 2024
NCT02410473 Active, not recruiting Evaluation of Coagulation Testing in Patients Undergoing Cardiac Surgery April 2015 December 2023
NCT03303248 Active, not recruiting N/A Evaluation of Web-based Transition Education to Enhance Transition Readiness August 27, 2018 December 30, 2024
NCT03363932 Active, not recruiting French Observatory of Congenital Ventricular Septal Defect With Pulmonary Overload June 1, 2018 June 2030
NCT04130243 Active, not recruiting Biomarkers in Pediatric Congenital Heart Disease and PAH December 5, 2017 December 1, 2024
NCT06392555 Active, not recruiting Fetal Heart Ultrasound Suspicious Radiographic Finding Identification - Reader Study May 3, 2024 July 2024
NCT03130777 Active, not recruiting N/A ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent August 22, 2017 June 2032
NCT00513240 Completed Phase 1/Phase 2 Erythropoetin Neuroprotection for Neonatal Cardiac Surgery September 2006 September 2015
NCT00538785 Completed Phase 2 A Study to Evaluate MEDI-524 In Children With Hemodynamically Significant Congenital Heart Disease October 2005 June 2008
NCT00556231 Completed Multi-site Near Infrared Spectroscopy (NIRS) Monitoring of Children During Exercise November 2007 December 2012
NCT00564122 Completed The Accuracy of an Artificially-intelligent Stethoscope December 2007 June 2008
NCT00585013 Completed Phase 1/Phase 2 Inhaled NO as an Anti-inflammatory and Anti-reperfusion Agent in Infants and Children Undergoing Cardiopulmonary Bypass January 2008 June 2011
NCT00693498 Completed N/A Washed Versus Standard Blood Cell Transfusions in Pediatric Open Heart Surgery July 2008 November 2009
NCT00713635 Completed Prenatal Effects of Congenital Heart Disease (CHD) on Neurodevelopmental Outcome December 2010 January 2016
NCT00751712 Completed Cerebral Oximetric Monitoring of the Posterior Circulation May 2006 April 2008
NCT00848250 Completed N/A Angiotensin Converting Enzyme Inhibitors During Cardiopulmonary Bypass in Infants and Children September 2008 July 2010
NCT00868101 Completed Phase 1/Phase 2 The Effect of Remote Ischemic Preconditioning Applied in Children the Day Before Open Heart Surgery January 2008 December 2009
NCT00911833 Completed The Roles of Trust and Respect in Patient Reactions to Race-based and Personalized Medicine Vignettes: An Experimental Study May 19, 2009 March 30, 2011
NCT00930800 Completed N/A Exercise Training in Children With Congenital Heart Defect December 2007 November 2008
NCT00934843 Completed N/A Preoperative Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass March 2007 September 2011
NCT00989911 Completed N/A Endothelin Blockade in Patients With Single Ventricle Physiology May 2010 March 2013
NCT00994994 Completed N/A Tranexamic Acid in Pediatric Cardiac Surgery January 2006 April 2008
NCT01006629 Completed Phase 2/Phase 3 Palivizumab for Prevention of Severe Respiratory Syncytial Virus Infection in Russian Children November 2009 July 2010
NCT02133573 Completed Phase 2 Randomized Trial of Maternal Progesterone Therapy July 2014 November 2021
NCT00165945 Completed 4-D Visualization Using Magnetic Resonance Imaging (MRI) in the Congenital Heart Disease Population June 2004 March 2010
NCT00165984 Completed Influence of Genetic Polymorphisms on Ventricular Structure and Function in Patients With Single Ventricle Anatomy January 2004 August 2010
NCT00238810 Completed Relationship of Brain Natriuretic Peptide (BNP) Levels to Cardiac Diagnosis, Operation Performed, Post-operative Course and Outcome April 2005 November 2014
NCT00284570 Completed Pro-Calcitonin Levels Following Pediatric Cardiac Surgery January 2006 March 2007
NCT00308230 Completed N/A Pilot Study of B-Type Natrieutic Peptide (BNP) Levels in Patients With Congenital Heart Disease(BNP) December 2001 September 2004
NCT00341133 Completed Genetic Analysis of Left-Right Axis Formations December 13, 1999
NCT00350220 Completed Phase 2 Transfusion Strategies in Pediatric Cardiothoracic Surgery July 2006 September 2009
NCT00374088 Completed Phase 2 N-Acetylcysteine in Neonatal Congenital Heart Surgery (INACT Study) February 2005 June 2008
NCT00399555 Completed Neurodevelopmental Outcomes in Hypoplastic Left Heart Syndrome November 2006 July 2009
NCT00412386 Completed Abnormal 3-D MRI Flow Patterns in Adolescents Patients With Bicuspid Aortic Valve December 2006 March 2012
NCT00446108 Completed Retrospective Pulmonary Valve Replacement Imaging February 2007 November 2012
NCT01045356 Completed Pharmacokinetics of Tranexamic Acid (TXA) in Children Undergoing Repair of Congenital Heart Defects Utilizing Cardiopulmonary Bypass January 2010 December 2014
NCT01063712 Completed Phase 2 Safety and Effectiveness of the Device "Nit-Occlud® PDA-R" June 2009 December 2010
NCT01069510 Completed Phase 2 Spironolactone in Adult Congenital Heart Disease February 2010 March 2017
NCT01126372 Completed Prediction of Feeding Problems in Prostaglandin-dependent Prematurely Born Infants With Congenital Heart Disease May 2010 June 2013
NCT01135485 Completed Evaluation of Panel Reactive Antibody in Children Following Stage I Palliation for Hypoplastic Left Heart Syndrome March 2010 December 2016
NCT01178710 Completed N/A Effect of Simvastatin on Cardiac Function September 2010 July 2012
NCT01189981 Completed Phase 2 Effect of eHealth Encouragements to Intensive Exercise in Adolescents With Congenital Heart Disease October 2010 May 2014
NCT01202916 Completed Quality of Life Among Children With Congenital Heart Disease September 2009 September 2011
NCT01228305 Completed N/A Acetaminophen for Oxidative Stress After Cardiopulmonary Bypass July 2011 March 2014
NCT01260259 Completed N/A Seattle Cardiorenal Remote Ischemic Preconditioning Trial December 2010 August 2013
NCT01280227 Completed N/A Supporting Patient Provider Communication in Paediatric Care January 2005 July 2016
NCT01287026 Completed Phase 1/Phase 2 Real-time MRI Right Heart Catheterization Using Passive Catheters February 23, 2011 March 21, 2019
NCT01368705 Completed Phase 4 Nitrogen Balance in Infants After Post Cardiothoracic Surgery August 2009 June 2012
NCT01479049 Completed N/A The Myocardial Protective Effects of a Moderate-potassium Blood Cardioplegia in Pediatric Cardiac Surgery October 2009 October 2010
NCT01484886 Completed N/A Restrictive Versus Liberal Transfusion Protocol in Infants Undergoing Cardiac Surgery January 2012 September 2014
NCT01501786 Completed N/A Does Ketamine Attenuate Depression of Respiratory and Cardiac Functions January 2012 May 2013
NCT01503307 Completed Parenting After Infant Congenital Heart Defect Diagnosis January 2009 July 2016
NCT01531985 Completed Urine and Serum Biomarkers for Early Detection of Acute Kidney Injury April 2010 March 2012
NCT01548950 Completed N/A Drug Therapy and Surgery in Congenital Heart Disease With Pulmonary Hypertension September 2011 March 2020
NCT01572363 Completed N/A Fontan Patients: Comprehensive Evaluation of Pulmonary Circulation and Ventricular Function April 2012 March 2014
NCT01579513 Completed N/A Corticosteroid Therapy in Neonates Undergoing Cardiopulmonary Bypass June 2012 December 19, 2018
NCT01616394 Completed Postoperative Troponin in Children With Congenital Heart Disease February 2012 October 2014
NCT01656941 Completed Genetic Determinants of Congenital Heart Disease Outcomes March 2011 March 16, 2017
NCT01656993 Completed Antiplatelet Activity of Aspirin in Infants After Aortopulmonary and Cavopulmonary Shunts November 2012 December 2014
NCT01665261 Completed Newborn Screening for Congenital Heart Disease July 2012 February 2013
NCT01669057 Completed Study on Clinical Prognosis, Risk Factors and Genetic Basis of Congenital Heart Disease October 2011 August 2014
NCT01723332 Completed N/A The CHAPTER II Study - Congenital Heart Adolescents Participating in Transition Evaluation Research November 2012 December 1, 2016
NCT01739088 Completed N/A Pediatric Remote Ischemic Pre-conditioning Prior to Complex Cardiac Surgery March 2013 March 31, 2017
NCT01749059 Completed The Impact of Implementing a Universal Newborn Screening for Critical Congenital Heart Disease June 2012 October 2016
NCT01762124 Completed N/A Study of the Native Outflow Tract Transcatheter Pulmonary Valve (TPV) October 2012 July 2020
NCT01774890 Completed ST2, a Novel Biomarker for Cardiac Remodeling in Adults With Congenital Heart Disease March 2013 January 2017
NCT01810978 Completed N/A Synbiotics in Infants With Cyanotic Congenital Heart Disease October 2012 May 2013
NCT01821287 Completed Nutritional Failure in Infants With Single Ventricle Congenital Heart Disease September 2010 October 2013
NCT01822769 Completed N/A Cardiopulmonary Rehabilitation for Adolescents and Adults With Congenital Heart Disease April 2013 December 2017
NCT01834976 Completed Cardiac Biomarker in Pediatric Heart Disease November 2012 December 2014
NCT01841177 Completed Phase 2 Evaluating Precision of Therapy - Milrinone April 2013 August 2020
NCT01849120 Completed NIRS Predict Low Cardiac Output State in Neonates and Infants in Cardiac Surgery May 2013 September 2015
NCT01909583 Completed N/A Pediatric Cardiac Surgery Pre-operative Counselling Study June 2013 September 2015
NCT01929174 Completed Diffuse Myocardial Fibrosis in Fontan Patients August 1, 2013 March 1, 2019
NCT01941667 Completed N/A Transitional Telehealth Home Care: REACH July 2012 July 2017
NCT01952171 Completed The Genetic Basis of Congenital Heart Disease in Africa September 17, 2013
NCT01966237 Completed Milrinone Pharmacokinetics and Acute Kidney Injury September 2013 July 2018
NCT01977222 Completed N/A Improving Functional Capacity in Fontan Patients Through Inspiratory Muscle Training December 2013 March 2015
NCT02026557 Completed Mortality Among Children With Congenital Heart Defects in Norway January 1994 July 2017
NCT02043379 Completed N/A Post-bypass Prophylactic IVIG in Infants and Neonates May 2014 June 2015
NCT02064179 Completed Assessment of the Efficacy of the First Aspirin Dose in Children Undergoing Surgery for Congenital Heart Disease (CHD) Who Require Post-operative Antiplatelet Therapy April 2014 June 2015
NCT02074527 Completed CHAIN_brazilian Registry of Congenital HeArt Disease INtervention and Angiography October 2012 December 2015
NCT02112448 Completed N/A Continuous Infusion Versus Bolus Dosing for Pain Control After Pediatric Cardiothoracic Surgery June 2014 May 2016
NCT00027170 Completed Technical Development of Cardiovascular Magnetic Resonance Imaging November 26, 2001 November 19, 2020
NCT02193243 Completed Value of 6-minute Walk Test in Grown Ups With Congenital Heart Defects (GUCH) June 2013 August 2014
NCT02283255 Completed N/A Cardiovascular, Pulmonary and Skeletal Muscle Evaluation Postoperative in Fontan Patients: Effects of Exercise Training January 31, 2013 October 30, 2020
NCT02287753 Completed N/A Relationship Between Parameters of VOT Using NIRS and Clinical Outcomes in Pediatric Cardiac Surgery November 2013 December 2016
NCT02326649 Completed Noninvasive Measurement of CO Using Impedance Cardiography in Patients With CHD December 2014 March 2016
NCT02352675 Completed Determination of the Minimal Concentration of Antifibrinolytics Required to Inhibit t-PA-activated Fibrinolysis April 2015 March 2016
NCT02378857 Completed Fontan Circulation and Cardiopulmonary Function: Prognostic Factors, Hemodynamics and Long-term Effects March 2015 April 26, 2019
NCT02389491 Completed N/A Effect of a High Density Formula on Growth and Safety in Congenital Heart Disease Infants March 2015 October 2015
NCT02433990 Completed Risk Factors for Acquired Cardiovascular Disease in Adults With Congenital Heart Disease April 2014 August 24, 2019
NCT02438293 Completed 'The Impact of Rhinovirus Infections in Paediatric Cardiac Surgery' June 2015 June 2018
NCT02463292 Completed Quality of Life in Young Adults With Congenital Heart Disease May 2015 May 2016
NCT02475759 Completed N/A Nutritional Prehabilitation Program and Cardiac Surgery Outcome in Pediatrics November 1, 2017 November 1, 2019
NCT02537392 Completed N/A Multi-micronutrient Supplementation During Peri-conception and Congenital Heart Disease September 2015 December 2019
NCT02549625 Completed Phase 1 Phase I Safety and Feasibility Study of Intracoronary Delivery of Autologous Bone Marrow Derived Mononuclear Cells August 2015 November 2020
NCT02567786 Completed N/A Fresh Frozen Plasma and Plasmalyte ® for Priming Cardiopulmonary Bypass in Infants and Children October 2015 July 2018
NCT02587039 Completed N/A An Intervention to Reduce Delirium After Cardiac Surgery June 2014 December 2015
NCT02614417 Completed Sleep-disordered Breathing in Eisenmenger Syndrome June 2013 September 2015
NCT02647541 Completed N/A Preoperative Nutritional Intervention and Outcomes of Children Submitted to Heart Surgery for Congenital Heart Diseases February 2011 November 2013
NCT02675361 Completed N/A Effectiveness of a Transition Program for Adolescents With Congenital Heart Disease in the Transition to Adulthood July 1, 2016 June 30, 2021
NCT02692443 Completed SVR III: Brain Connectome and Neurodevelopmental Outcomes August 2015 April 30, 2022
NCT02700646 Completed N/A Improving Motor Skill Development in Infants After Cardiac Surgery January 5, 2016 May 13, 2019
NCT02700737 Completed N/A Evaluation of Image-Based Modelling on Clinical Decisions in Coarctation of the Aorta May 2016 August 2016
NCT02710825 Completed N/A Osteopathy and Children With Congenital Heart Disease Surgery May 2016 February 23, 2017
NCT02728128 Completed Platelet and Tissue cAMP: Novel Biomarkers of Milrinone Efficacy in Children August 2016 August 17, 2017
NCT02737644 Completed Peri-conception Key Nutritional Factors and Congenital Heart Disease March 2016 December 30, 2020
NCT02746029 Completed Cardiac Murmurs in Children: Predictive Value of Cardiac Markers September 2016 October 2021
NCT02753348 Completed Copenhagen Baby Heart April 2016 November 2018
NCT02759263 Completed N/A Improving Neurodevelopment in Adolescents With Congenital Heart Disease June 2016 October 2018
NCT02814539 Completed Brain Function in Children With Congenital Heart Disease (CHD) March 2016 September 2019
NCT02839486 Completed Vancomycin and Cefoxitin During Pediatric Cardiopulmonary Bypass October 1, 2017 July 1, 2019
NCT02877238 Completed Phase 2 Remote Preconditioning and Myocardial Protection August 2016 May 2017
NCT02895334 Completed N/A MyHeartBaby: An Initial Evaluation of the MyHeartBaby Psychosocial Telemedicine Program July 2015 April 7, 2017
NCT02968264 Completed Tetralogy of Fallot for Life June 8, 2015 July 1, 2022
NCT02980393 Completed N/A Smart Heart Trial: Structured Lifestyle Intervention for Overweight and Obese Youth With Operated Heart Defects May 2012 November 2016
NCT02990754 Completed N/A Fearless Physical Activity: Getting and Keeping Ontarians With Congenital Heart Disease Active October 25, 2016 June 30, 2018
NCT03014700 Completed Phase 4 Fibrinogen Concentrate vs Cryoprecipitate March 2016 April 25, 2018
NCT03048071 Completed Morbimortality of Contegra Duct Replacements Versus Homografts in Pulmonary Position February 14, 2017 June 1, 2017
NCT03050112 Completed N/A Long-term Quality of Life of Patients With a Congenital Heart Disease, Treated by Surgery in Adulthood at the Brugmann Hospital. February 14, 2017 June 1, 2017
NCT03082716 Completed Phase 2 Custodiol Versus Blood Cardioplegaia in Paediatric Cardiac Surgery March 16, 2016 March 29, 2018
NCT03088345 Completed Phase 2/Phase 3 Early Use of Vasopressin in Post-Fontan Management March 6, 2017 January 28, 2019
NCT03099967 Completed Cardiac Troponin T After Transcatheter Closure of the Interatrial Septum January 1, 2005 January 1, 2017
NCT03119090 Completed Fontan Imaging Biomarkers (FIB) Study September 2015 July 2021
NCT03144258 Completed Evaluation of the Microcirculation During the Corrective Surgery of Congenital Heart Defects in Children February 20, 2018 December 30, 2018
NCT03150953 Completed N/A Evaluation of a Novel Patient Warming System During MRI May 26, 2016 November 30, 2018
NCT03153137 Completed Phase 3 Clinical Study Assessing the Efficacy and Safety of Macitentan in Fontan-palliated Subjects August 14, 2017 July 26, 2021
NCT03154476 Completed Phase 3 Role of Sildenafil for Fontan Associated Liver Disease (SiFALD) Study July 5, 2017 June 30, 2019
NCT03170024 Completed Health Literacy in Adults With Congenital Heart Disease October 31, 2015 May 7, 2021
NCT03170778 Completed Ocular and Vision Problems in Patients After Fontan Operation February 13, 2016 May 1, 2022
NCT03214120 Completed Does Modified Ultrafiltration Affect Thromboelastography Results? January 8, 2018 January 1, 2019
NCT03248830 Completed Non-invasive Hemoglobin Monitoring in Congenital Heart Diseased Children February 20, 2018 September 10, 2019
NCT03255850 Completed The Impact of Congenital Heart Disease on the Psychological Well Being and Quality of Life in the Hong Kong Chinese Adolescents August 15, 2017 August 31, 2018
NCT03297918 Completed N/A Impact of a Structural Phonation Training on Respiratory Muscle Function in Patients With Structural Heart Disease February 15, 2018 October 10, 2018
NCT03316508 Completed Copeptin- Relevance as a Perioperative Marker in Pediatric Cardiac Surgery June 14, 2017 August 10, 2019
NCT03347214 Completed dbGaP Protocol: The Pediatric Cardiac Genetics Consortium (PCGC) October 20, 2017 January 10, 2020
NCT03360370 Completed Neurodevelopmental Disorders in Children With Congenital Heart Disease December 6, 2017 June 6, 2018
NCT03379831 Completed Correlation Between Quality of Life and Aerobic Physical Fitness of Patients With a Systemic Right Ventricle January 12, 2018 July 4, 2019
NCT03429335 Completed N/A Just TRAC It! Transitioning Responsibly to Adult Care Using Smart Phone Technology April 17, 2018 December 1, 2020
NCT03435354 Completed N/A Enhanced Physical Activity Support in Congenital Heart Disease Clinical Care March 5, 2018 May 31, 2023
NCT03469843 Completed Characterization of the Cardiac Reinnervation of Patients With Transposition of the Great Arteries Long After Repair With the Arterial Switch Operation. Correlation With Electrocardiographic and Exercise Test Parameters April 19, 2018 September 1, 2019
NCT03470428 Completed Clinical Characteristics and Associations of the "Good Fontan" Patient March 5, 2018 April 18, 2023
NCT03487302 Completed White Matter Hyperintensities Burden in Adult Patients With Cyanotic Congenital Heart Disease: a Pilot Study October 17, 2017 December 31, 2021
NCT03488797 Completed N/A Web-based Motor Intervention to Increase Health Related Physical Fitness in Children With Congenital Heart Disease June 1, 2018 November 17, 2020
NCT03513718 Completed Acute Kidney Injury After Cardiac Surgery on CPB October 1, 2017 September 5, 2023
NCT03541291 Completed N/A Utility of MRI With Doppler Ultrasound Gating for Advanced Fetal Monitoring May 30, 2018 March 22, 2024
NCT03551600 Completed Splanchnic and Renal Tissue Oxygenation During Enteral Feedings in Neonates With Patent Ductus Arteriosus October 2015 June 30, 2022
NCT03563391 Completed N/A A Study to Evaluate the Effects of a New Formula on the Growth, Safety and Tolerance of Infants With Growth Failure January 30, 2018 May 30, 2020
NCT03564522 Completed Image-based Multi-scale Modeling Framework of the Cardiopulmonary System: Longitudinal Calibration and Assessment of Therapies in Pediatric Pulmonary Hypertension April 1, 2017 July 28, 2023
NCT03583775 Completed 3D Cine Cardiovascular Magnetic Resonance November 1, 2019 October 4, 2021
NCT03611374 Completed N/A Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER) Study June 7, 2019 April 6, 2023
NCT03620071 Completed N/A GoalKeeper: Intelligent Information Sharing for Children With Medical Complexity April 19, 2019 March 17, 2021
NCT03667703 Completed Phase 4 Stress Ulcer Prophylaxis Versus Placebo in Critically Ill Infants With Congenital Heart Disease March 10, 2019 June 30, 2022
NCT03677232 Completed The Living Experience of Hong Kong Chinese Adolescents With CHD. August 11, 2017 August 31, 2018
NCT03678909 Completed Cardiac Biomarkers in Patients With Single Ventricle Physiology March 1, 2018 July 30, 2020
NCT03757312 Completed N/A A Pilot Study of Optic Nerve Ultrasound Following Cardiopulmonary Bypass April 24, 2019 January 16, 2020
NCT03833843 Completed Sudden Cardiac Death in Systemic Right Ventricle September 1, 2018 September 1, 2019
NCT03853837 Completed Ventricular and Pulmonary Vascular Reserve After the Fontan Operation August 30, 2018 July 21, 2022
NCT03854149 Completed Apixaban in Adults With Congenital Heart Disease and Atrial Arrhythmias: the PROTECT-AR Study July 1, 2019 May 30, 2023
NCT03867903 Completed BabySparks Developmental Application Pilot Study March 14, 2019 May 17, 2023
NCT03877965 Completed Pharmacokinetics and Safety Profile of Digoxin in Infants With Single Ventricle Congenital Heart Disease August 5, 2019 January 17, 2022
NCT03882788 Completed N/A The Effect of Anesthesia on Neurodevelopmental Outcome (NDO) April 22, 2013 November 19, 2020
NCT03886935 Completed Metabolic Remodeling in Fontan Patients January 1, 2017 January 1, 2019
NCT03912025 Completed The Relationship Between Having a Positive Mindset and Exercise Capacity in Patients With Congenital Heart Disease January 30, 2020 April 25, 2021
NCT03913520 Completed N/A Outcome of Patients With Congenital Heart Disease April 28, 2019 October 1, 2020
NCT03917706 Completed Development of a Quality of Life Assessment Tool for Adult Patients With a Congenital Heart Disease, Having Had Surgery During Childhood April 1, 2018 July 15, 2019
NCT03931096 Completed Quality of Life Assessment of Children With Congenital Heart Disease Aged 5 to 7 Years February 1, 2019 December 31, 2019
NCT03957824 Completed PREVENTION-ACHD Risk Score January 1, 2015 June 30, 2018
NCT03999320 Completed N/A Sophrology and Congenital Heart Disease July 19, 2019 September 19, 2023
NCT04030481 Completed Effects of Anesthetic Techniques on Renal Function January 1, 2019 September 30, 2019
NCT04041557 Completed Executive Functions in Adults With Congenital Heart Disease January 1, 2017 September 20, 2018
NCT04056104 Completed N/A Improving Critical Congenital Heart Disease Screening With Addition of Perfusion Measurements October 23, 2019 December 12, 2021
NCT04136379 Completed Comparison of Home and Standard Clinic Monitoring of INR in Patients With CHD September 30, 2019 October 31, 2021
NCT04138745 Completed Transverse Thoracic Plane Block in the Pediatric Cardiac Patient January 1, 2018 December 31, 2020
NCT04151160 Completed Point of Care Ultrasound Measurements of Perioperative Edema in Infants With Congenital Heart Disease January 13, 2020 July 1, 2021
NCT04152330 Completed N/A Proposal for Parental Guidance and Early Stimulation in Children With Congenital Heart Disease: Randomized Trial November 30, 2019 August 30, 2020
NCT04163653 Completed Lymphatic Morphology of Fontan Patients January 1, 2018 January 1, 2022
NCT04194502 Completed N/A Coronary Artery Assessement by TEE in Congenital Heart Disease April 19, 2017 July 31, 2019
NCT04221048 Completed Accuracy of Risk Prediction Scores in Pregnant Women December 30, 2018 October 30, 2019
NCT04231591 Completed NT-proBNP Levels in the Prediction of Intrapartum and Postpartum Events in Adult Congenital Heart Disease Patients November 13, 2019 December 1, 2023
NCT04260204 Completed N/A Effect of Retrograde Autologous Blood Priming on Pulmonary Mechanics in Pediatric Cardiac Surgery January 2, 2015 January 25, 2020
NCT04264650 Completed N/A Effectiveness of an mHealth Intervention for Youth With Congenital Heart Disease June 1, 2016 February 28, 2018
NCT04278625 Completed Pharmacokinetics of Acetaminophen in Pediatric Patients With Congenital Heart Disease March 23, 2021 February 16, 2022
NCT04336384 Completed Impact of Covid-19 in Congenital Heart Disease March 1, 2020 December 30, 2020
NCT04416230 Completed N/A Post-Op Massage in Infants With Congenital Heart Disease May 1, 2012 May 30, 2014
NCT04417790 Completed Utility of Lung Ultrasound in the Estimation of Extravascular Lung Water in Pediatric Population August 10, 2019 August 30, 2020
NCT04454294 Completed N/A Determining the Effect of Two Different Methods in Children to Maintain Drain Patency After Cardiac Surgery July 28, 2018 December 12, 2019
NCT04498728 Completed Cardiac Acute Transitioning Care to Home (CATCH) App Data Repository July 29, 2020 November 15, 2021
NCT04534335 Completed SNOO Smart Sleeper for Infants With CHD February 4, 2020 September 12, 2022
NCT04536194 Completed Phase 3 Dopamine Versus Norepinephrine Under General Anesthesia October 10, 2020 September 30, 2021
NCT04570878 Completed N/A Subcostal Transverse Abdominis Plane Block for Epigastric Cardiac Pacemaker Operation January 15, 2021 July 31, 2023
NCT04613934 Completed Redesigning the Care Journey of Patients With Single-ventricle Congenital Heart Disease February 4, 2020 October 16, 2020
NCT04672538 Completed N/A Fontan Physiology Ventilation Strategy March 2, 2021 May 15, 2023
NCT04740177 Completed Epidemiology of Congenital Heart Disease in France February 1, 2020 December 30, 2020
NCT04795076 Completed N/A Effect of Feeding With Nutrient Dense Formula in Malnourished Infants and Children With Congenital Heart Defects April 3, 2021 February 9, 2022
NCT04812210 Completed Quality of Life and Neurodevelopment Assessment of Children With Congenital Heart Disease Aged 2 to 4 Years April 1, 2021 December 30, 2021
NCT04814888 Completed 3D Airway Model for Pediatric Patients September 3, 2019 March 16, 2020
NCT04815577 Completed Evolution of Cardiopulmonary Fitness in Children With Congenital Heart Disease March 1, 2020 February 20, 2021
NCT04842851 Completed Cardiac Resynchronization Therapy in Congenital Heart Diseases With Systemic Right Ventricle January 1, 2004 December 31, 2020
NCT04848168 Completed Comparison of PRISM III, PIM2 and PELOD Scoring Systems February 1, 2019 May 1, 2019
NCT04897672 Completed 2D-speckle Tracking in Pediatric Renal Chronic Disease May 1, 2021 December 30, 2021
NCT04902768 Completed Assessment of Patterns of Patient Reported Outcomes in Adults With Congenital Heart Disease - International Study II August 1, 2019 December 31, 2022
NCT04933786 Completed N/A Digital Health Nudging in Adolescents With Congenital Heart Disease June 1, 2021 November 1, 2022
NCT04956952 Completed N/A Enhanced External Counterpulsation in Patients With Fontan Circulation March 31, 2022 May 17, 2023
NCT05049590 Completed Phase 3 Acute Normovolemic Hemodilution in Complex Cardiac Surgery February 28, 2022 June 22, 2023
NCT05105880 Completed Auscultation and Pulse Oximetry Combined Screening of Neonatal Congenital Heart Disease January 1, 2018 July 1, 2020
NCT05118152 Completed Correlation Between 3D Echocardiography and Cardiopulmonary Exercise Testing in Patients With Single Ventricle June 1, 2021 June 30, 2022
NCT05154864 Completed Ultrafiltration in Pediatric Cardiac Surgery: An Observational Cohort Study August 1, 2020 June 30, 2021
NCT05312177 Completed Congenital Heart Disease: Impact on Learning and Development in Down Syndrome (CHILD-DS) May 1, 2022 December 31, 2023
NCT05332860 Completed Extubation Times in Postoperative Congenital Cardiovascular Surgeries May 1, 2020 February 15, 2021
NCT05344872 Completed N/A ATC Vs PSV for Ventilatory Weaning of Pediatrics Postcardiac Surgery April 15, 2022 January 25, 2023
NCT05425173 Completed N/A Limbs Range of Motion Exercises Along With Chest Physical Therapy After Correction of Congenital Heart Diseases in ICU June 20, 2022 December 30, 2022
NCT05525195 Completed Influence of Preop Fibrinogen on Blood in Pediatric Cardiac Surgery September 17, 2022 February 10, 2023
NCT05526469 Completed N/A Ultrasound-Guided Serratus Anterior Plane Block Versus Erector Spinae Plane Block in Pediatric Cardiac Surgery July 24, 2022 March 31, 2023
NCT05526768 Completed N/A Evaluation of VITLS Compared to Traditional Inpatient Monitoring in Cardiac Shunt-Dependent Children October 26, 2022 May 10, 2023
NCT05665712 Completed Pediatric Enhanced Recovery After Cardiac Surgery November 1, 2019 August 15, 2023
NCT05717049 Completed Phase 2 Theophylline Effects in the Fontan Circulation February 9, 2023 September 15, 2023
NCT05763238 Completed N/A Exercise Training in Children With Corrective Cardiac Surgeries March 1, 2023 February 15, 2024
NCT05824650 Completed Frailty and Non-Fragile Congenital Heart Disease April 20, 2023 February 15, 2024
NCT05853263 Completed N/A Morphine IV vs Paracetamol IV in Neonates and Infants After Cardiac Surgery March 9, 2016 July 20, 2020
NCT05934578 Completed N/A Lymphatic Function in Patients With Fontan Circulation: Effect of Physical Training September 26, 2022 December 22, 2022
NCT05976204 Completed Prognostic Value of NLR, TLR, and ALC in Predicting ToF Primary Repair Outcome January 1, 2020 June 30, 2023
NCT06107491 Completed N/A Preoperative Educational Videos on Maternal Stress Whose Children Received Congenital Heart Disease Surgery: During COVID-19 Panic October 4, 2021 January 1, 2023
NCT06186258 Completed Infective Endocarditis in Percutaneous Pulmonary Revalvulation: Comparison Between Melody and Sapien Valves December 17, 2021 July 31, 2023
NCT06292910 Completed Central Venous to Arterial CO2 Difference and Low Cardiac Output Syndrome Related Outcomes in Children After Cardiac Surgery August 8, 2021 December 26, 2023
NCT06295575 Completed N/A Effect of Probiotics on Patients With Congenital Heart Disease Following Cardiopulmonary Bypass June 1, 2021 July 1, 2022
NCT06347510 Completed The Level of sST2 in Pediatric Heart Failure August 16, 2021 February 16, 2024
NCT05101746 Enrolling by invitation Phase 2/Phase 3 Nitric Oxide Effect on Brain and Kidney in Pediatric Patients Undergoing Cardiopulmonary Bypass April 25, 2022 November 2024
NCT03322345 Enrolling by invitation Characterizing the Effect of Dopamine on Markers of Lymph Re-circulation in Fontan-associated Protein-losing Enteropathy April 9, 2019 April 1, 2025
NCT05195788 Enrolling by invitation N/A Cardiac Rehabilitation in Congenital Heart Disease: Effects on Brain and Cognitive Functions February 7, 2022 April 2024
NCT03149341 Enrolling by invitation MRI and Computational Simulation Cardiology Study February 2008 February 2025
NCT04150120 Enrolling by invitation N/A eHealth as an Aid for Facilitating and Supporting Self-management in Families With Long-term Childhood Illness October 15, 2019 December 31, 2024
NCT05454501 Enrolling by invitation N/A The Effects of Telerehabilitation and Exercise Training in Pediatric Arrhythmia Patients With Pacemakers May 31, 2022 September 2023
NCT04548804 Enrolling by invitation N/A Better Mechanistic Understanding of and Risk Stratification for Ventricular Tachyarrhythmias Through ECGI June 10, 2020 February 12, 2026
NCT05670132 Not yet recruiting N/A Neuro-cardiac Rehabilitation in Youth With Congenital Heart Disease (QUALINEUROREHAB) April 1, 2023 April 1, 2025
NCT06434207 Not yet recruiting Extracellular Vesicle Micro RNA Profiling in Congenital Heart Disease: Fetal-Maternal Regulation in Neonatal Thrombosis June 1, 2024 June 1, 2025
NCT05546008 Not yet recruiting Comparison Between Multislice CT and Echocardiography in Diagnosis of Pediatric Congenital Heart Disease September 10, 2022 November 10, 2022
NCT05916976 Not yet recruiting N/A Repaired Tetralogy of Fallot: Risc Score From MRI & Clinical Data to Predict the Need for Change of Treatment October 15, 2023 April 30, 2026
NCT05891210 Not yet recruiting Nutrition in Congenital Heart Disease September 1, 2023 December 1, 2024
NCT06221150 Not yet recruiting N/A Bilateral Two Levels Serratus Anterior Plane Block in Pediatric Cardiac Surgery With Median Sternotomy February 20, 2024 February 2025
NCT05524324 Not yet recruiting N/A Cardiac Resynchronization Therapy in Adult Congenital Heart Disease With Systemic Right Ventricle: RIGHT-CRT September 2022 March 2025
NCT05869825 Not yet recruiting N/A HFNC vs NIPPV Following Extubation May 2024 May 2026
NCT06193863 Not yet recruiting An Observational Study to Learn More About How Safe Rivaroxaban is And How Well it Works in Children With Congenital Heart Disease Who Had a Heart Surgery Called the Fontan Procedure May 31, 2024 December 31, 2026
NCT06325280 Not yet recruiting Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease June 1, 2024 December 31, 2027
NCT05852106 Not yet recruiting N/A The Effect of 3D Heart Modelling on Family Quality of Life and Surgical Success July 1, 2023 February 1, 2024
NCT06267430 Not yet recruiting N/A Learning by Heart: The Effectiveness of an EF Training Program for Pre-schoolers With a Severe CHD March 1, 2024 April 30, 2027
NCT05687292 Not yet recruiting Application of a Clinical Decision Support System to Reduce Mechanical Ventilation Duration After Cardiac Surgery September 2024 March 2026
NCT05580510 Not yet recruiting Phase 2/Phase 3 " Evaluation of Safety and Efficacy of Empagliflozin and Sacubitril/Valsartan for CHF With Reduced Ejection Fraction in ACHD " February 6, 2023 March 29, 2024
NCT05568849 Not yet recruiting N/A Optical Coherence Tomography Angiography (OCTA) in Children's Cardiac Surgery October 2022 March 2024
NCT06406517 Not yet recruiting Phase 3 Comparative Effectiveness of Gadopiclenol for Evaluation of Adult Congenital Heart Anatomy and Hemodynamics May 2024 June 2025
NCT05185232 Not yet recruiting Congenital Heart Initiative-Redefining Outcomes and Navigation to Adult Centered Care April 1, 2022 June 30, 2024
NCT06373627 Not yet recruiting N/A Procedural Pain Management by Multimodal Sedation Analgesia Combining Hypnosis in Children With Congenital Heart Disease May 2, 2024 May 3, 2025
NCT06418373 Not yet recruiting N/A Development and Polit Study of Get Ready With my Heart Program June 1, 2024 May 31, 2025
NCT06081855 Not yet recruiting Predictors of Aortic Root Dilatation in Tetralogy of Fallot Patients January 1, 2024 May 1, 2025
NCT06281639 Not yet recruiting RAPID: a Comparison Study of a Novel Ultrasound Device of Automated Congenital Heart Imaging June 1, 2024 April 1, 2025
NCT06080074 Not yet recruiting N/A Multicenter Trial of ECMO in Children With Severe Cardiac Failure Using the Cardiohelp System July 1, 2024 September 30, 2027
NCT06072937 Not yet recruiting N/A IntelliStent for Pulmonary Flow Adjustment in Congenital Heart Disease and Dilated Cardiomyopathy June 4, 2024 June 4, 2026
NCT05849025 Recruiting A Study of Invasive Hemodynamic for MACHD Registry October 16, 2023 October 2026
NCT06270485 Recruiting N/A Influence of Positive-End-Expiratory-Pressure (PEEP) on Cardiac Output in Mechanically Ventilated Children November 27, 2023 June 2025
NCT05550324 Recruiting iPSC Repository of Pediatric Cardiovascular Disease July 2, 2021 December 31, 2025
NCT03775954 Recruiting Fetal Electrophysiologic Abnormalities in High-Risk Pregnancies Associated With Fetal Demise July 1, 2018 April 30, 2024
NCT03837574 Recruiting French National Registry of Patients With Tetralogy of Fallot and Implantable Cardioverter Defibrillator December 1, 2010 December 31, 2030
NCT03840928 Recruiting PatientSpot Formerly Known as ArthritisPower April 1, 2015 March 1, 2025
NCT05583656 Recruiting INSPIRIS RESILIA Valve in Pulmonary Position August 12, 2019 February 1, 2024
NCT05610787 Recruiting N/A EXCOR Active Driving System for the EXCOR Pediatric VAD IDE Study November 14, 2022 January 2024
NCT05637814 Recruiting N/A Dynamic Critical Congenital Heart Screening With Addition of Perfusion Measurements August 17, 2023 December 31, 2027
NCT05647213 Recruiting Phase 1 Autologous Induced Pluripotent Stem Cells of Cardiac Lineage for Congenital Heart Disease February 3, 2023 February 2029
NCT05654272 Recruiting Development of CIRC Technologies September 9, 2022 September 9, 2042
NCT03891160 Recruiting N/A Implementing Models for Mechanical Circulatory Support Presurgical Assessment in Congenital Heart Disease Treatment January 22, 2020 July 31, 2026
NCT05683067 Recruiting Microcirculation and Vascular Function After Fontan Surgery May 12, 2023 October 1, 2024
NCT05684562 Recruiting Pulmonary Determinants of Cardiorespiratory Fitness in Fontan Patients December 26, 2023 December 30, 2024
NCT03944837 Recruiting N/A Acute Maternal Hyperoxygenation in CHD April 26, 2019 December 31, 2025
NCT05702203 Recruiting N/A Creative Music Therapy in Newborns With Congenital Heart Disease November 22, 2022 October 24, 2026
NCT05713591 Recruiting N/A Transition Care Model for Adolescents With Congenital Heart Disease May 3, 2021 December 31, 2024
NCT01192048 Recruiting Genetics of Congenital Heart Disease December 2009 December 2025
NCT05774158 Recruiting Investigation of Adults With Congenital Heart Disease in the Scope of the ICF December 1, 2022 December 1, 2023
NCT05809310 Recruiting N/A Effects Branch PA Stenting d-TGA, ToF and TA April 18, 2023 September 30, 2025
NCT05819788 Recruiting FFP Usage in Pediatric CV Surgery August 28, 2023 May 2024
NCT06298344 Recruiting Early Phase 1 The Role of Thiamine After Transcatheter Closure in Children With Left-to-Right Shunt Congenital Heart Disease May 1, 2024 January 1, 2025
NCT05828524 Recruiting Outcome of Balloon Pulmonary Valvuloplasty in Patients With Congenital Pulmonary Stenosis in Terms of Reverse Right Ventricular Remodelling and Functional Exercise Capacity January 10, 2021 December 2024
NCT05838079 Recruiting Copenhagen Baby Heart Study - Impact November 1, 2018 July 2029
NCT01653223 Recruiting N/A Myocardial Protection Effect of Simvastatin Undergoing Cardiac Surgery January 2013 December 2026
NCT04233775 Recruiting Altered Cerebral Growth and Development in Infants With Congenital Heart Disease January 1, 2020 December 31, 2024
NCT05853705 Recruiting N/A Strong Hearts: A Remote, App-Enabled, Exercise Program for Patients With Congenital Heart Disease (Strong Hearts App) January 12, 2024 January 2025
NCT05862909 Recruiting N/A Efficacy of a Web-Based Emotion Regulation Intervention for Patients With Congenital Heart Disease August 5, 2022 September 1, 2023
NCT04299828 Recruiting Evaluation of Pro-Inflammatory Leukocyte Activity in Patients Undergoing Cardiac Surgery May 31, 2022 December 2024
NCT05865119 Recruiting N/A OPTImal Treatment of Sinus VENOSUS Defect May 12, 2023 May 12, 2029
NCT05881564 Recruiting N/A Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery May 10, 2023 May 12, 2026
NCT04437069 Recruiting N/A Improving Patient and Family Health Using Family-Centered Outcomes and Shared Decision-Making October 1, 2020 June 30, 2025
NCT04463446 Recruiting N/A The Impact of an Innovative eHealth Transition Intervention on Self-Management Skills Among Young Adults With Congenital Heart Disease January 10, 2022 June 2024
NCT04464655 Recruiting A 10-Minute Cardiovascular Magnetic Resonance Protocol for Cardiac Disease December 12, 2019 January 31, 2025
NCT05902013 Recruiting N/A Video Laryngoscopy Versus Direct Laryngoscopy for Nasotracheal Intubation September 21, 2022 December 31, 2023
NCT05907109 Recruiting N/A NeuroCardio Baby Research Outpatient Clinic: Study on the Neurodevelopment of Infants With Congenital Heart Disease in Brazil March 16, 2021 December 31, 2025
NCT04575883 Recruiting N/A HIIT in Youth With Congenital Heart Disease (MedBIKE) November 22, 2022 December 31, 2026
NCT02258724 Recruiting Swiss National Registry of Grown up Congenital Heart Disease Patients September 2013 December 2033
NCT05968521 Recruiting N/A Cardiac Rehabilitation for Young People March 4, 2024 November 30, 2024
NCT06371937 Recruiting iPSC Biobank of Biomarkers Diversity in Cardiovascular Disease May 1, 2024 June 30, 2033
NCT04702373 Recruiting Phase 3 Training in Exercise Activities and Motion for Growth (TEAM 4 Growth) RCT February 23, 2021 June 30, 2024
NCT02414321 Recruiting The Role of the Pulmonary Vasculature in the Fontan Circulation June 2015 October 30, 2024
NCT04738474 Recruiting N/A Assessing and Promoting Resilience in Patients With Adult Congenital Heart Disease March 15, 2023 December 2024
NCT05996211 Recruiting The Swiss Neurodevelopmental Outcome Registry for Children With CHD January 1, 2019 December 31, 2032
NCT00243776 Recruiting Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development April 2005 December 31, 2025
NCT05997680 Recruiting N/A A Parent-child Yoga Intervention for Reducing Attention Deficits in Children With Congenital Heart Disease: A Feasibility Study October 1, 2023 October 1, 2025
NCT06025864 Recruiting N/A Protocol to Support Breastfeeding for Postpartum Women and Mothers of Babies With Congenital Heart Disease July 1, 2022 February 20, 2024
NCT06041685 Recruiting N/A Effect of Local Warming for Arterial Catheterization in Pediatric Anesthesia September 22, 2023 December 31, 2024
NCT04848844 Recruiting The PAtients pResenTing With COngenital HeaRt DIseAse Register (ARTORIA-R) September 2, 2020 July 30, 2030
NCT06075251 Recruiting N/A Online Support 4 CHD Kids & Caregivers February 15, 2024 December 31, 2028
NCT06078943 Recruiting N/A ABL90 FP MC Neonatal Arterial, Venous, Capillary Blood March 17, 2023 January 30, 2024
NCT04920643 Recruiting N/A High-exchange ULTrafiltration to Enhance Recovery After Pediatric Cardiac Surgery September 28, 2021 June 30, 2025
NCT04992793 Recruiting Paediatric Brain Injury Following Cardiac Interventions September 9, 2021 November 1, 2024
NCT04998643 Recruiting Muscle Catabolism and Outcomes in Children Following Cardiac Surgery July 15, 2022 June 1, 2024
NCT05006404 Recruiting N/A Autus Valve Pivotal Study February 5, 2024 February 2036
NCT05034354 Recruiting N/A Virtual Remote Physiological Monitoring Program of Children With Heart Disease February 8, 2022 December 31, 2024
NCT06089902 Recruiting European Prospective Registry on Anomalous Aortic Origin of the Coronary Arteries January 1, 2019 January 1, 2029
NCT05077774 Recruiting N/A Harmony TPV Post-Approval Study October 25, 2021 March 2035
NCT05081115 Recruiting Stress Echo 2030: the Novel ABCDE-(FGLPR) Protocol to Define the Future of Imaging April 1, 2021 December 31, 2030
NCT06171698 Recruiting N/A Impedance During Cardiac Catheterization to Build a Non-Invasive Cardiac Output Algorithm March 30, 2023 December 31, 2027
NCT05122962 Recruiting Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases November 1, 2021 October 2026
NCT03152773 Recruiting N/A Heart Catheterization Using Magnetic Resonance Imaging (MRI) Fluoroscopy and Passive Guidewires August 2, 2017 December 30, 2025
NCT05129631 Recruiting N/A HEARTPrep: A Virtually-delivered Psychosocial Intervention for Mothers Expecting a Baby With Congenital Heart Disease July 14, 2023 December 1, 2024
NCT05140343 Recruiting N/A Mobile Electrocardiogram Monitoring for Detecting Arrhythmias in Children April 7, 2021 August 30, 2024
NCT03209583 Recruiting ATrial Tachycardia PAcing Therapy in Congenital Heart September 1, 2018 September 1, 2024
NCT05213598 Recruiting Fontan Associated Liver Disease and the Evaluation of Biomarkers for Disease Severity Assessment September 7, 2022 June 30, 2051
NCT05241418 Recruiting Atrial Late Gadolinium Enhancement in Patients With Repaired Congenital Heart Disease March 23, 2022 June 30, 2029
NCT05258981 Recruiting N/A The Relationship Between Brain MRI Phenotypes, Genes and Cognitive Outcome in CHD Adults July 1, 2022 June 2026
NCT05262907 Recruiting N/A Ventripoint Single Ventricle Study July 8, 2022 August 1, 2025
NCT05263843 Recruiting Gender Difference in NET Activation in Patients With Congenital Heart Disease and Heart Failure February 22, 2022 February 23, 2025
NCT03408340 Recruiting Phase 4 Paravertebral Nerve Blocks in Neonates July 18, 2018 December 2024
NCT06190210 Recruiting Predictive Value of Neurovascular Coupling in Infants With COngenital Heart Disease December 1, 2023 September 30, 2027
NCT06196801 Recruiting Efficacy of Triple-Combination Therapy in Severe PAH-CHD June 17, 2022 December 1, 2025
NCT05373498 Recruiting Resuscitation Registry in CHD August 18, 2022 December 31, 2032
NCT05386173 Recruiting Effect of Fetal Aortic Valvuloplasty on Outcomes January 1, 2021 December 31, 2029
NCT05454254 Recruiting N/A Effect of Muscle Strengthening Training in Adults With Fontan Circulation August 15, 2022 November 30, 2023
NCT05489263 Recruiting A Predictive Score System for AKI Following Pediatric Cardiac Surgery April 1, 2022 June 30, 2023
NCT06244940 Recruiting N/A The Sequencing for Detection in Congenital Heart Disease (SD-CHD) Study January 9, 2024 October 1, 2026
NCT03626480 Recruiting Peri-operative Nutrition in Infants With Congenital Heart Disease July 9, 2018 September 1, 2028
NCT06055556 Suspended N/A Partial Heart Transplantation August 4, 2023 December 30, 2030
NCT02046135 Terminated Phase 2 Sodium Bicarbonate to Prevent Acute Kidney Injury in Children Undergoing Cardiac Surgery September 2013 July 22, 2017
NCT00215085 Terminated Cardiac Tumors in Children May 2005 November 2006
NCT01639937 Terminated Myocardial Perfusion and Scarring in Congenital Heart Disease October 24, 2012 December 12, 2019
NCT04054115 Terminated Phase 1 Acute Effects of the Prostaglandin (Alprostadil) on Cerebral and Pulmonary Flow July 23, 2019 November 9, 2022
NCT00359099 Terminated Hepatitis C in Adults Who Underwent Congenital Heart Surgery Before Screening January 1980 July 2006
NCT03576534 Terminated N/A Pre Bypass Ultrafiltration (PBUF) in Children Requiring Cardiopulmonary Bypass October 3, 2019 September 13, 2021
NCT01291797 Terminated Use of AEEG as Predictor of Long-term Motor Outcome in Neonates With Congenital Heart Disease July 2010 June 2011
NCT04181255 Terminated Phase 1 Cold Heart Study: A Randomized Pilot Trial of Surfactant Therapy February 25, 2020 June 12, 2020
NCT03156764 Terminated Qp/Qs Ratio by Noninvasive Methods in Children With Shunt Dependent Pulmonary Circulation May 23, 2017 July 21, 2020
NCT00208689 Terminated Critical Congenital Heart Defect (CHD) Outcomes in Children January 2004
NCT01698567 Terminated Phase 1 Antithrombin III in Infants With Cardiopulmonary Bypass (CPB) July 2012 March 2016
NCT00919945 Terminated Phase 2 Impact of Early Enteral Feeding on Splanchnic Blood Flow After Surgery for Critical Heart Disease in the Newborn January 2009 July 2014
NCT00335036 Terminated N/A Pediatric Lead Extractability and Survival Evaluation (PLEASE) June 2006 January 2009
NCT00757510 Terminated Congenital Heart Disease Research Registry January 2008 February 2010
NCT02551107 Terminated N/A Infant Nasal Nitric Oxide Levels in Congenital Heart Disease December 2015 January 12, 2018
NCT02004756 Terminated Phase 1/Phase 2 Mechanisms of Dysfunction and the Influence of Exercise on Cardiac and Musculoskeletal Function January 2010 April 2015
NCT02060825 Terminated The Use of Optical Oximetry in Determining Gastrointestinal Complications After the Hybrid Procedure November 2012 September 2016
NCT03417999 Terminated Phase 1 Pharmacokinetic Study of Intranasal Dexmedetomidine in Pediatric Patients With Congenital Heart Disease June 14, 2018 October 12, 2021
NCT03361189 Terminated Phase 2/Phase 3 Specialized Pacing for Patients With Congenital Heart Disease May 9, 2021 November 3, 2021
NCT02564796 Terminated Phase 2 Erythropoietin to Prevent Unnecessary Transfusions In Patients With Cyanotic CHD - A Prospective Control Trial November 2016 June 2020
NCT04090697 Terminated Phase 1/Phase 2 Use of Oxandrolone to Promote Growth in Infants With HLHS December 20, 2019 September 19, 2023
NCT00850720 Terminated Study of Possible Brain Hormone Problems After Open Heart Surgery in Infants March 2009 October 2009
NCT02769624 Terminated Phase 2 Acute Effects of Inhaled Treprostinil in Fontan Patients February 21, 2017 September 21, 2018
NCT04434001 Terminated Phase 2 ZEPLAST- PED: ZEro_PLASma Trial in Small Infants Undergoing Cardiac Surgery February 27, 2020 June 30, 2021
NCT04768634 Terminated N/A Predicting Arrhythmogenic Risk in Congenital Heart Patients: the PRECISION Study March 23, 2021 February 6, 2024
NCT05314868 Terminated Retrospective Evaluation of Photo-oxidized Decellularized Bovine Pericardium in Cardiac Repair or Reconstruction Surgery March 31, 2022 November 30, 2022
NCT03935178 Terminated Evaluating Right Ventricular (RV) Size and Function Using the Upper Valley RV Algorithm and Novel Imaging Modalities August 5, 2019 January 30, 2022
NCT00483951 Terminated Cardiovascular Disease Screening January 28, 2008 November 3, 2020
NCT02408848 Terminated The Value of Three Dimensional Echocardiography in Congenital Cardiac Surgery March 2015 September 2016
NCT01319045 Terminated N/A Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart Disease June 2011 May 2013
NCT05066399 Unknown status Fetal Cardiac Magnetic Resonance in Detection of CHD May 11, 2021 September 2023
NCT03425734 Unknown status Phase 2 The Effect of Dexmedetomidine on Kidney Perfusion in Paediatric Patients May 20, 2017 July 20, 2018
NCT05264181 Unknown status Transcatheter Pulmonary Valve Implantation With SAPIEN 3 Valve September 1, 2021 August 1, 2022
NCT05090306 Unknown status Interpretation of Fetal Echocardiography by Artificial Intelligence November 1, 2020 October 31, 2022
NCT01184404 Unknown status N/A Bosentan Improves Clinical Outcome of Adults With Congenital Heart Disease or Mitral Valve Lesions Who Undergo CArdiac Surgery September 2011
NCT04205461 Unknown status Prospective Evaluation of Programmed Ventricular Stimulation Before Pulmonary Valve Replacement in Patients With Tetralogy of Fallot January 1, 2020 December 31, 2023
NCT04202796 Unknown status Catheter Ablation in Congenital Heart Disease: French National Prospective Registry January 1, 2020 December 31, 2023
NCT01633801 Unknown status N/A Use of High Flows in Pediatric Cardiac Surgical Patients August 2012 December 2012
NCT05109806 Unknown status N/A Psychological Functioning of Children and Adolescents With CHD andTheir Parents, An Intervention Based Study May 7, 2021 July 2022
NCT01662011 Unknown status Phase 3 Application of Neurally Adjusted Ventilatory Assist to Children After Congenital Cardiac Surgery January 2010 December 2012
NCT01668264 Unknown status Phase 2 Imaging Assessment of Diastolic Function
NCT04262037 Unknown status N/A A Comparative Study of Three Modes of Ventilation During CPB in Pediatrics With Pulmonary Hypertension Undergoing Congenital Heart Surgeries August 1, 2019 November 2020
NCT03119155 Unknown status Improvement on Diagnosis of Fetal Congenital Heart Disease Based on Multi-center Collaboration in China December 1, 2018 December 31, 2021
NCT04292483 Unknown status Pulmonary Capillary Recruitment in Fontan Patients June 11, 2020 December 31, 2023
NCT04303793 Unknown status N/A Procedural Outcomes of Percutaneous PDA Closure: Comparative Study Between Different Devices. June 1, 2020 June 2022
NCT04311918 Unknown status The Effect of Fluids Flushed in Pediatric Cardiac Catheterization Procedures on Lung Ultrasound Score March 1, 2020 March 15, 2021
NCT03850223 Unknown status Clinical Audit On Management Of Congenital Heart Disease In ACUH March 1, 2020 December 1, 2021
NCT01827059 Unknown status Phase 2 Bosentan In Exercise Induced Pulmonary Arterial Hypertension in CongenitaL Heart diseasE October 2013 June 2018
NCT04152967 Unknown status N/A New Designed ePTFE Valved Conduits for Surgical Reconstruction of Right-ventricular Outflow Tract April 1, 2020 November 30, 2022
NCT01134302 Unknown status Phase 3 Hybrid Versus Norwood Management Strategies in Infants Undergoing Single Ventricle Palliation March 2010 March 2012
NCT01845506 Unknown status N/A The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS December 2021 December 2023
NCT01891188 Unknown status Using Near-infrared Spectroscopy (NIRS) Monitor to Noninvasively Evaluate Hepatic Venous Saturation June 2013 July 2016
NCT04453761 Unknown status Phase 4 Thiamine Influenced on Substrate Energy Effectiveness in Indonesian Children Undergoing Cardiopulmonary Bypass July 1, 2018 December 1, 2022
NCT03542968 Unknown status N/A Imaging by 4 DFlow in Patients With Tetralogy of Fallot October 12, 2017 April 11, 2020
NCT05196438 Unknown status Patterns of Congenital Heart Diseases at Sohag University Hospital January 15, 2022 January 2023
NCT05203874 Unknown status Contribution of Multimodal Imaging in Early Coarctation January 1, 2022 December 29, 2022
NCT05378685 Unknown status N/A Nasal vs. Oral Intubation for Neonates Requiring Cardiac Surgery July 1, 2018 June 30, 2022
NCT04801251 Unknown status N/A Red Flags for Cardiac Examination for Early Detection of Congenital Heart Disease October 20, 2021 December 20, 2022
NCT04807621 Unknown status Phase 2 Platelets or Fibrinogen as First-line Treatment for Bleeding During Pedatric Heart Surgery March 14, 2018 August 2022
NCT00668824 Unknown status Phase 4 Improved Diagnosis of Congenital Heart Disease by Magnetic Resonance Imaging Using Vasovist March 2007 December 2009
NCT02618824 Unknown status Phase 2 Role of Terminal Warm Blood Cardioplegia as Myocardial Protection in the Use of Histidine-Tryptophan-Ketoglutarate Cardioplegia in Complex Congenital Heart Surgery December 2015 December 2016
NCT03786497 Unknown status Protecting Brains and Saving Futures - the PBSF Protocol January 1, 2021 December 31, 2023
NCT02652741 Unknown status Phase 2/Phase 3 Orodispersible Minitablets of Enalapril in Young Children With Heart Failure Due to Congenital Heart Disease January 2016 June 2017
NCT02654678 Unknown status Phase 2/Phase 3 Follow-up Safety Trial in Children With Chronic Heart Failure Therapy Receiving Orodispersible Minitablets of Enalapril March 2016 April 2018
NCT02659462 Unknown status Cardio Pulmonary Exercise Testing in Patients Post the Fontan Palliation in Comparison With Patients With Repaired Congenital Heart Disease and Healthy Volunteers. October 2015 December 2016
NCT04825054 Unknown status N/A Cardiopulmonary Effect of Mechanical Ventilation in Children With Right Ventricular Hypertrophy February 25, 2021 December 31, 2021
NCT02700100 Unknown status N/A Study to Assess Safety of the Pulmonary Valved Conduit (PV-001) in Subjects Undergoing Right Ventricular Outflow Tract Reconstruction June 2016 April 2022
NCT03217240 Unknown status Integrated Computational modelIng of Right Heart Mechanics and Blood Flow Dynamics in Congenital Heart Disease June 5, 2017 August 30, 2019
NCT03928002 Unknown status N/A 4DFlow Magnetic Resonance Imaging in Patients With Pulmonary Hypertension Associated With Congenital Heart Disease May 30, 2018 October 1, 2020
NCT02731248 Unknown status Pulse Oximeter Screening in Congenital Heart Disease April 2016 May 2017
NCT04093011 Unknown status Perioperative Outcome of Congenital Heart Disease Surgery in Childhood January 1, 2012 December 2019
NCT04973514 Unknown status Perioperative Transfusion Strategies in Adult Congenital Heart Disease Patients Undergoing Cardiac Surgery July 20, 2022 December 30, 2022
NCT02791061 Unknown status Study of RV Remodeling in Congenital Heart Disease January 2013 October 2017
NCT02825472 Unknown status N/A Exercise Training in Grown-up Congenital Heart Disease February 2016 September 2017
NCT04993794 Unknown status N/A Additive Anti-inflammatory Action for Critically Ill Patients With Cardiovascular Surgery (Xuebijing) IV January 1, 2021 December 31, 2022
NCT03366597 Unknown status N/A The Research of the Effect of Sevoflurane on Brain-protection of Cardiac Surgery in Infants. January 20, 2018 December 28, 2022
NCT00772135 Unknown status N/A Reversibility by Sildenafil of Exercise-Induced Abnormal Right Ventricular Pressure Response in ASD and VSD-Operated Patients September 2008 April 2009
NCT03558269 Unknown status Phase 1/Phase 2 Autologous Umbilical Cord Blood Treatment of Neonate With CHD February 1, 2019 April 1, 2023
NCT02897323 Unknown status Northwest Adult Congenital Heart Disease Observatory November 14, 2016 October 2020
NCT02914392 Unknown status Study on the Relationship Between Maternal Exposure to Environmental Factors and Fetal Congenital Heart Disease May 18, 2017 December 2020
NCT03629574 Unknown status N/A Mechanical Ventilation During Cardiopulmonary Bypass August 20, 2018 December 2019
NCT02970071 Unknown status The Application Value of STIC in the Diagnosis of Fetal Complex Congenital Heart Disease April 25, 2017 December 2020
NCT05052177 Unknown status Percutaneous Edge To Edge Repair for the Treatment of Severe Tricuspid Valve Regurgitation in High-surgical Risk Patients With Systemic Right Ventricle : a Multicentric French Cohort (PETER-TRESRIV) July 1, 2020 October 30, 2022
NCT02996630 Unknown status N/A Assessing Neurodevelopment in Congenital Heart Disease. May 2013 May 2018
NCT03471936 Unknown status N/A Right Ventricular Diastolic Function in Chronic Adverse RV Loading And Congenital Heart Disease July 7, 2016 August 1, 2022
NCT04484922 Unknown status N/A Dexmedetomidine Neuroprotection in Pediatric Cardiac Surgery August 25, 2020 May 31, 2023
NCT04496050 Unknown status Effects of Prostaglandin E1 Treatment on Pyloric Wall in Newborns May 6, 2019 November 30, 2020
NCT01278771 Unknown status Coronary Anomalies in Congenital Heart Disease March 2011
NCT04600700 Unknown status Use of a Predictive Analytics Algorithm to Optimize Weaning of Inotropes Following Pediatric Cardiac Surgery July 1, 2021 March 1, 2023
NCT03207295 Unknown status N/A Impact of Nesiritide on Early Postoperative Recovery After Total Cavo-Pulmonary Connection Surgery in Children July 5, 2017 December 1, 2020
NCT04631965 Unknown status Healthcare Transition of Adolescents With Chronic Health Conditions September 1, 2017 December 2023
NCT03657823 Unknown status Fetal Growth and Pregnancy Complications Among Women With Heart Disease May 15, 2018 May 31, 2020
NCT01045252 Unknown status Study of Hemodynamics of Neonates by Echocardiography and USCOM October 2008 December 2011
NCT04737135 Unknown status Myocardial FIbrosis in Repaired Tetralogy of FAllot- FIFA Study) July 9, 2018 June 30, 2022
NCT01300221 Withdrawn Real-time 3-Dimensional Echocardiography for Assessment of Cardiac Function and Congenital Heart Disease February 2011 March 2011
NCT03946462 Withdrawn Phase 1 Nitric Oxide During CPB to Reduce AKI in Neonates October 2021 March 2023
NCT02599857 Withdrawn N/A The Effects of a CONCOR Smartphone Application January 1, 2017 May 1, 2017
NCT02614664 Withdrawn Changes in Cerebral Oxygenation During Laparoscopy in Patients With Single Ventricle Anatomy November 2015 October 11, 2017
NCT01914211 Withdrawn The Role of Tranexamic Acid in Reducing Blood Transfusion Requirements After Cardiopulmonary Bypass in Neonates July 2013 June 2014
NCT01082536 Withdrawn Analysis of Cerebral Perfusion Using Head Ultrasound and Multisource Detector Near Infrared Spectroscopy (NIRS) Imaging March 28, 2013 May 2019
NCT02352662 Withdrawn Peri-operative Assessment of Coagulopathy in Neonates and Infants Undergoing Cardiac Surgery April 2015 April 2017
NCT01980979 Withdrawn N/A Efficacy of Remodulin in Adults With Congenital Heart Disease (ACHD) and Pulmonary Hypertension November 2013 December 2015
NCT03142685 Withdrawn N/A Utility of Bowel Ultrasound in Diagnosing Necrotizing Eneterocolitis in Congenital Heart Disease January 1, 2017 June 30, 2018
NCT03282292 Withdrawn N/A Central Venous Catheter Insertion Site and Colonization in Pediatric Cardiac Surgery September 12, 2017 October 12, 2019
NCT04259684 Withdrawn Phase 2/Phase 3 Nitric Oxide During Cardiopulmonary Bypass in Neonates to Reduce Risk of Acute Kidney Injury October 20, 2019 October 20, 2019
NCT01607983 Withdrawn Phase 3 Effects of Pulmonary Vasodilation Upon VA Coupling in Fontan Patients June 2012 December 2017
NCT00770705 Withdrawn Phase 2 Parenteral Phenoxybenzamine During Congenital Heart Disease Surgery October 2008 August 2010
NCT02709200 Withdrawn Effect of Dexmedetomidine on Pacemaker Function Following Cardiac Surgery February 2016 March 11, 2019
Disase is a (Disease Ontology)
DOID:114
Cross Reference ID (Disease Ontology)
ICD10CM:Q24.9
Cross Reference ID (Disease Ontology)
ICD9CM:746.9
Cross Reference ID (Disease Ontology)
MESH:D006330
Cross Reference ID (Disease Ontology)
NCI:C34666
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:268315002
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0018798
Exact Synonym (Disease Ontology)
Congenital anomaly of heart
Exact Synonym (Disease Ontology)
congenital heart defect
Exact Synonym (Disease Ontology)
Congenital Heart Defects
Exact Synonym (Disease Ontology)
heart defect
Exact Synonym (Disease Ontology)
Heart Malformation
Disase Synonym (Disease Ontology)
Heart-congenital defect