severe congenital neutropenia
Information
- Disease name
- severe congenital neutropenia
- Disease ID
- DOID:0050590
- Description
- "A neutropenia characterized by a maturation arrest of granulopoiesis at the level or promyelocytes and early onset of severe bacterial infections." [url:https\://ghr.nlm.nih.gov/condition/severe-congenital-neutropenia, url:https\://www.ncbi.nlm.nih.gov/pubmed/17133096]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT01966367 | Active, not recruiting | Phase 1/Phase 2 | CD34+ (Non-Malignant) Stem Cell Selection for Patients Receiving Allogeneic Stem Cell Transplantation | March 2013 | February 2030 |
| NCT00295971 | Completed | Phase 1 | Donor Stem Cell Transplant in Treating Young Patients With Myelodysplastic Syndrome, Leukemia, Bone Marrow Failure Syndrome, or Severe Immunodeficiency Disease | April 2005 | December 2011 |
| NCT00301834 | Completed | Phase 2 | Alemtuzumab, Fludarabine, and Busulfan Followed By Donor Stem Cell Transplant in Treating Young Patients With Hematologic Disorders | January 2005 | September 2011 |
| NCT00305708 | Completed | Phase 1/Phase 2 | Busulfan, Antithymocyte Globulin, and Fludarabine Followed By a Donor Stem Cell Transplant in Treating Young Patients With Blood Disorders, Bone Marrow Disorders, Chronic Myelogenous Leukemia in First Chronic Phase, or Acute Myeloid Leukemia in First Remission | August 2000 | July 2004 |
| NCT01529827 | Completed | Phase 2 | Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies | February 28, 2012 | August 29, 2019 |
| NCT01917708 | Completed | Phase 1 | Bone Marrow Transplant With Abatacept for Non-Malignant Diseases | January 2014 | September 19, 2019 |
| NCT00176852 | Completed | Phase 2/Phase 3 | Stem Cell Transplant for Hemoglobinopathy | June 2002 | January 2020 |
| NCT04844177 | Not yet recruiting | Phase 2 | Total Lymphoid Irradiation Pre-HSCT in Severe Congenital Neutropenia | April 14, 2021 | April 2026 |
| NCT02179359 | Recruiting | N/A | Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies | September 2, 2014 | August 2025 |
| NCT02720679 | Recruiting | Investigation of the Genetics of Hematologic Diseases | June 17, 2016 | July 2050 | |
| NCT05687474 | Recruiting | Baby Detect : Genomic Newborn Screening | September 1, 2022 | August 31, 2025 | |
| NCT01319851 | Terminated | N/A | Alefacept and Allogeneic Hematopoietic Stem Cell Transplantation | September 2010 | September 2013 |
- Disase is a (Disease Ontology)
- DOID:1227
- Cross Reference ID (Disease Ontology)
- GARD:13592
- Cross Reference ID (Disease Ontology)
- ICD10CM:D70
- Cross Reference ID (Disease Ontology)
- MIM:PS202700
- Cross Reference ID (Disease Ontology)
- ORDO:42738
- OrphaNumber from OrphaNet (Orphanet)
- 42738