Annotation Detail

Information
Associated Genes
CXCR4
Associated Variants
CXCR4 MUTATION
CXCR4 MUTATION
Associated Disease
HIV Infections
Source Database
DisGeNET
Description
The interaction of HIV-1 and target cells involves sequential binding of the viral gp120 Env protein to the CD4 receptor and a chemokine co-receptor (either CCR5 or CXCR4).
Pubmed
25966986
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
1
Original source reporting the Gene Disease association
BeFree,GAD,LHGDN
DisGENET score for the Gene Disease association
0.0949168283993425
Drugs