Annotation Detail

Information
Associated Genes
CXCR4
Associated Variants
CXCR4 MUTATION
CXCR4 MUTATION
Associated Disease
multiple myeloma
Source Database
DisGeNET
Description
It has previously been shown that SDF1/CXCR4-induced migration is dependent on activation of downstream BTK in chronic lymphocytic leukaemia (CLL) and multiple myeloma.
Pubmed
25294819
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00597172118576667
Drugs