Annotation Detail

Information
Associated Genes
CXCR4
Associated Variants
CXCR4 MUTATION
CXCR4 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Recent evidence suggests that CXCR4-mediated proliferation and metastasis of tumor cells is regulated by CXCR7 through its scavenging of chemokine CXCL12.
Pubmed
25884570
Section of the abstract supporting the evidence
BACKGROUND
Number of the section of the abstract supporting the evidence
1
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.245644501421039
Drugs