Annotation Detail
Information
- Associated Genes
- CXCR4
- Associated Variants
-
CXCR4 MUTATION
CXCR4 MUTATION - Associated Disease
- bipolar disorder
- Source Database
- DisGeNET
- Description
- Treatment of the CXCR4(+) NPCs with a pharmacological inhibitor of glycogen synthase kinase 3, a known regulator of WNT signaling, was found to rescue a progenitor proliferation deficit in the BD patient NPCs.
- Pubmed
- 25733313
- Section of the abstract supporting the evidence
- ALL_TEXT_3/3
- Number of the section of the abstract supporting the evidence
- 3
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs