Annotation Detail

Information
Associated Genes
CXCR4
Associated Variants
CXCR4 MUTATION
CXCR4 MUTATION
Associated Disease
Neoplasm Metastasis
Source Database
DisGeNET
Description
Finally, IL-24 when combined with CXCR4 inhibitors (AMD3100, SJA5) or with CXCR4 siRNA demonstrated enhanced inhibitory activity on tumor cell migration.
Pubmed
25775124
Section of the abstract supporting the evidence
PRINCIPAL FINDINGS
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
14
Original source reporting the Gene Disease association
BeFree,CTD_human,LHGDN
DisGENET score for the Gene Disease association
0.245644501421039
Drugs