multiple endocrine neoplasia type 2B
Information
- Disease name
- multiple endocrine neoplasia type 2B
- Disease ID
- DOID:10016
- Description
- "A multiple endocrine neoplasia characterized by medullary thyroid carcinoma, pheochromocytoma, multiple mucosal neuromas and intestinal ganglioneuromas, and often a marfanoid habitus and other skeletal abnormalities." [url:http\://en.wikipedia.org/wiki/Multiple_endocrine_neoplasia_type_2b, url:http\://ghr.nlm.nih.gov/condition/multiple-endocrine-neoplasia, url:http\://www.merckmanuals.com/professional/endocrine_and_metabolic_disorders/multiple_endocrine_neoplasia_men_syndromes/multiple_endocrine_neoplasia_type_2b_men_2b.html, url:https\://www.ncbi.nlm.nih.gov/pubmed/15965261, url:https\://www.rarediseases.org/rare-disease-information/rare-diseases/byID/1244/viewAbstract]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes | Mutation | Description | Source | Links |
---|
NCT ID | Status | Phase | Summary | Start date | Completion date |
---|---|---|---|---|---|
NCT00390325 | Completed | Phase 2 | Sorafenib Tosylate in Treating Patients With Metastatic, Locally Advanced, or Recurrent Medullary Thyroid Cancer | November 3, 2006 | December 22, 2022 |
NCT00514046 | Completed | Phase 1/Phase 2 | Vandetanib to Treat Children and Adolescents With Medullary Thyroid Cancer | July 20, 2007 | November 1, 2020 |
NCT03655223 | Enrolling by invitation | Early Check: Expanded Screening in Newborns | October 15, 2018 | December 31, 2025 | |
NCT01793168 | Recruiting | Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford | July 2010 | December 2100 | |
NCT02831179 | Withdrawn | Phase 1 | Veliparib, Capecitabine, and Temozolomide in Patients With Advanced, Metastatic, and Recurrent Neuroendocrine Tumor | December 2017 | February 2020 |
- Disase is a (Disease Ontology)
- DOID:3125
- Cross Reference ID (Disease Ontology)
- ICD10CM:E31.23
- Cross Reference ID (Disease Ontology)
- ICD9CM:258.03
- Cross Reference ID (Disease Ontology)
- MESH:D018814
- Cross Reference ID (Disease Ontology)
- MIM:162300
- Cross Reference ID (Disease Ontology)
- NCI:C3227
- Cross Reference ID (Disease Ontology)
- ORDO:247709
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:61530001
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0025269
- Exact Synonym (Disease Ontology)
- MEN type IIB
- Exact Synonym (Disease Ontology)
- MEN2B
- Exact Synonym (Disease Ontology)
- mucosal neuroma syndrome
- Exact Synonym (Disease Ontology)
- Multiple endocrine neoplasia, type 3
- Exact Synonym (Disease Ontology)
- Wagenmann-Froboese syndrome
- OrphaNumber from OrphaNet (Orphanet)
- 247709
- MeSH unique ID (MeSH (Medical Subject Headings))
- D018814