chr9:21367372:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr9:21,367,371-21,368,056 
hg38 chr9:21,367,372-21,368,057

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.001 squamous cell carcinoma NA BeFree Detail
<0.001 celiac disease NA BeFree Detail
<0.001 Chikungunya Fever NA BeFree Detail
<0.001 choriocarcinoma NA BeFree Detail
<0.001 colitis NA BeFree Detail
<0.001 ulcerative colitis NA BeFree Detail
<0.001 colorectal carcinoma NA BeFree Detail
<0.001 common variable immunodeficiency NA BeFree Detail
<0.001 Coronary Arteriosclerosis The results argue against the potential utility of drugs targeting type-I IFN pr... BeFree 25882064 Detail
<0.001 Coronary heart disease The results argue against the potential utility of drugs targeting type-I IFN pr... BeFree 25882064 Detail
<0.001 cryoglobulinemia NA BeFree Detail
<0.001 cystic fibrosis NA BeFree Detail
<0.001 Cytomegalovirus Infections NA BeFree Detail
<0.001 Hepatitis D Infection NA BeFree Detail
0.001 Dengue Fever NA BeFree Detail
0.001 dermatomyositis NA BeFree Detail
<0.001 dermoid cyst NA BeFree Detail
0.001 Diabetes NA BeFree Detail
0.001 diabetes mellitus NA BeFree Detail
0.001 Diabetes Mellitus, Insulin-Dependent NA BeFree Detail
<0.001 Down syndrome NA BeFree Detail
<0.001 Muscular Dystrophy, Duchenne NA BeFree Detail
<0.001 Ectromelia We showed that DC are the primary producers of type I interferons (T1-IFN), requ... BeFree 26202250 Detail
<0.001 encephalitis NA BeFree Detail
<0.001 Japanese encephalitis Delayed IFN response differentiates replication of West Nile virus and Japanese ... BeFree 25920530 Detail
<0.001 Experimental Autoimmune Encephalomyelitis NA BeFree Detail
<0.001 Venezuelan equine encephalomyelitis NA BeFree Detail
<0.001 Enterovirus Infections Our results suggest that enterovirus-induced miR-146a facilitates viral pathogen... BeFree 24561744 Detail
<0.001 Eosinophilia NA BeFree Detail
<0.001 erythromelalgia NA BeFree Detail
0.001 Fanconi anemia NA BeFree Detail
<0.001 Fatigue NA BeFree Detail
<0.001 Fatty Liver Hepatic steatosis is a risk factor for both liver disease progression and an imp... BeFree 25961570 Detail
<0.001 Foot-and-Mouth Disease NA BeFree Detail
<0.001 gingivitis NA BeFree Detail
0.002 glioblastoma We have previously shown that cysteine-rich 61 protein (CCN1) activates a type 1... BeFree 24895995 Detail
0.002 glioblastoma Delayed IFN response differentiates replication of West Nile virus and Japanese ... BeFree 25920530 Detail
0.002 Glioma NA BeFree Detail
<0.001 Graft-vs-Host Disease NA BeFree Detail
<0.001 hand, foot and mouth disease Those with mild HFMD had higher γ-IFN expression levels compared with those with... BeFree 25059424 Detail
<0.001 Hematological Disease NA BeFree Detail
<0.001 Severe Dengue NA BeFree Detail
0.002 hepatitis The identification of mutations in the HVR1 region of hepatitis type C virus (HC... BeFree 25588648 Detail
0.003 hepatitis A The identification of mutations in the HVR1 region of hepatitis type C virus (HC... BeFree 25588648 Detail
0.014 hepatitis B For HBeAg-positive patients and HBeAg-negative patients with genotype D infectio... BeFree 24738850 Detail
0.014 hepatitis B The study of on-treatment dynamics of HBV infection by means of combined quantit... BeFree 25034484 Detail
0.014 hepatitis B Then, we aimed to investigate the role of CYP27B1 polymorphisms in HBV treatment... BeFree 25060765 Detail
0.014 hepatitis B A total of 30 patients with CHB who achieved HBsAg seroclearance following peg-I... BeFree 25324041 Detail
0.014 hepatitis B In SVR to Peg-IFN/NUCs MiR-B-Index improved during-therapy and post-treatment re... BeFree 25350115 Detail
0.014 hepatitis B A total of 210 patients with chronic hepatitis C genotype 1 of high viral load (... BeFree 25914481 Detail
0.002 Hepatitis, Chronic NA BeFree Detail
0.030 hepatitis C The next phase of therapy will be combining several classes of DAAs without IFN ... BeFree 24636306 Detail
0.030 hepatitis C For patients infected with hepatitis C virus (HCV), the combination of the direc... BeFree 25101970 Detail
0.030 hepatitis C In addition, the results suggest new viral genomic attributes that might influen... BeFree 25150834 Detail
0.030 hepatitis C Noncirrhotic HCV treatment-naive patients and prior relapsers received response-... BeFree 25192745 Detail
0.030 hepatitis C Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infect... BeFree 25220206 Detail
0.030 hepatitis C In May 2011, boceprevir and telaprevir, two first-generation NS3/4A protease inh... BeFree 25229466 Detail
0.030 hepatitis C Treatment of hepatitis C virus (HCV) with pegylated interferon and ribavirin (IF... BeFree 25326107 Detail
0.030 hepatitis C This review will focus on the second-wave DAAs including protease inhibitors (PI... BeFree 25529082 Detail
0.030 hepatitis C Forty patients infected with hepatitis C virus (HCV) genotype 1 and starting ant... BeFree 25583751 Detail
0.030 hepatitis C Pegylated IFN-α-2a and ribavirin in the treatment of hepatitis C infection in ch... BeFree 25599750 Detail
0.030 hepatitis C Impaired induction of IL28B, related to IFNλ4 expression in PBMCs of IL28B-unfav... BeFree 25611696 Detail
0.030 hepatitis C Here, we discuss IFN-λ genetic polymorphisms and their role in HCV and other inf... BeFree 25634147 Detail
0.030 hepatitis C IFN-free regimens with direct antiviral agents (DAAs) against hepatitis C virus ... BeFree 25645644 Detail
0.030 hepatitis C Peg-IFN and ribavirin treatment for recurrence of genotype 2 and 3 hepatitis C a... BeFree 25650729 Detail
0.030 hepatitis C In this contest IFN-α therapy, a standard therapy for HCV-infection and lymphopr... BeFree 25700262 Detail
0.030 hepatitis C These findings expand our understanding of IFN-responses in HCV-infected individ... BeFree 25765354 Detail
0.030 hepatitis C We conducted an open-label trial to assess the efficacy and safety of sofosbuvir... BeFree 25847509 Detail
0.030 hepatitis C Between January 2006 and June 2012, a total of 180 patients with chronic infecti... BeFree 25852275 Detail
0.030 hepatitis C A total of 210 patients with chronic hepatitis C genotype 1 of high viral load (... BeFree 25914481 Detail
0.030 hepatitis C Hepatitis C virus (HCV) genotype 1 infections are significantly more difficult t... BeFree 25965701 Detail
0.030 hepatitis C To assess the accuracy and cost-effectiveness of the automated Abbott ARCHITECT ... BeFree 26018116 Detail
0.030 hepatitis C We demonstrated a marked polarization of NK cells toward cytotoxicity in respons... BeFree 26034208 Detail
0.030 hepatitis C Role of IL28B genotyping in patients with hepatitis C virus-associated mixed cry... BeFree 26060059 Detail
0.030 hepatitis C Sixty-one patients under suppressive antiretroviral therapy were included: 37 wi... BeFree 26181704 Detail
0.004 Herpes Simplex Infections NA BeFree Detail
<0.001 Herpesviridae Infections NA BeFree Detail
0.020 HIV Infections The OPERA study results show that PEG-IFN plus ribavirin is an effective treatme... BeFree 24583976 Detail
0.020 HIV Infections We modeled increased activation in HIV infection by priming human monocytes with... BeFree 24731171 Detail
0.020 HIV Infections To determine SVR and other response rates, identify SVR predictors and analyse d... BeFree 25041136 Detail
0.020 HIV Infections The specific reduction of miR-422a is associated with exogenous IFN-α treatment,... BeFree 25275557 Detail
0.020 HIV Infections In sum, we identified a novel mechanism of HIV-1-induced CXCL13 secretion-one ca... BeFree 25667414 Detail
0.020 HIV Infections Blimp-1 binds an IFN-stimulated response element within HIV-1 provirus, and it i... BeFree 25710909 Detail
0.020 HIV Infections The results suggest that the presence of the IFN+874A allele confers susceptibil... BeFree 25802474 Detail
0.020 HIV Infections Group 1 comprised HIV/HCV co-infected patients who were treated with highly acti... BeFree 25823618 Detail
0.020 HIV Infections These novel findings will be of great interest to those working on the roles of ... BeFree 25972534 Detail
<0.001 Hypertension, Portal NA BeFree Detail
<0.001 pulmonary hypertension NA BeFree Detail
<0.001 Immune System Diseases NA BeFree Detail
0.004 influenza The increased level of IFN-λ mRNA corresponded to significantly increased level ... BeFree 26104331 Detail
<0.001 ischemia NA BeFree Detail
<0.001 Kidney Diseases NA BeFree Detail
<0.001 Kidney Failure, Chronic NA BeFree Detail
<0.001 leprosy NA BeFree Detail
0.002 leukemia NA BeFree Detail
<0.001 chronic lymphocytic leukemia NA BeFree Detail
<0.001 hairy cell leukemia NA BeFree Detail
<0.001 lymphoid leukemia NA BeFree Detail
0.001 Acute lymphocytic leukemia NA BeFree Detail
0.001 Leukemia, Myelocytic, Acute NA BeFree Detail
<0.001 myeloid leukemia NA BeFree Detail
0.005 Myeloid Leukemia, Chronic NA BeFree Detail
0.001 Leukemia, Myeloid, Chronic-Phase NA BeFree Detail
<0.001 Adult T-Cell Lymphoma/Leukemia NA BeFree Detail
<0.001 leukopenia Logistic regression analysis showed that rs2305482 CC and neutrophil count at ba... BeFree 25515861 Detail
<0.001 lichen planus NA BeFree Detail
0.005 liver cirrhosis Of 326 patients with HCV-related chronic liver disease (252 with genotype 1b and... BeFree 24065124 Detail
0.005 liver cirrhosis The recent October 2014 approval of the fixed dose combination (FDC) of the NS5B... BeFree 25676581 Detail
0.003 Liver diseases Hepatic steatosis is a risk factor for both liver disease progression and an imp... BeFree 25961570 Detail
0.001 Liver neoplasms NA BeFree Detail
<0.001 Lung diseases NA BeFree Detail
<0.001 Lung Neoplasms NA BeFree Detail
0.006 Lupus Vulgaris Persistent production of IFN-α, the most abundant subtype measured in these pati... BeFree 25468480 Detail
<0.001 Lupus Erythematosus, Cutaneous NA BeFree Detail
0.006 Lupus Erythematosus, Discoid Persistent production of IFN-α, the most abundant subtype measured in these pati... BeFree 25468480 Detail
<0.001 lupus nephritis NA BeFree Detail
<0.001 Lyme disease RST1 isolates, which are more frequently associated with disseminated Lyme disea... BeFree 24945497 Detail
<0.001 lymphoma NA BeFree Detail
<0.001 Lymphoproliferative Disorders In this contest IFN-α therapy, a standard therapy for HCV-infection and lymphopr... BeFree 25700262 Detail
<0.001 malaria Interferon-γ (IFNG) microsatellite repeat and single nucleotide polymorphism hap... BeFree 25445652 Detail
<0.001 Malaria, Cerebral NA BeFree Detail
<0.001 Malignant neoplasm of stomach NA BeFree Detail
0.001 measles NA BeFree Detail
0.014 melanoma Expression of the IFITM proteins was found to delay the phosphorylation of IFN r... BeFree 25228491 Detail
0.014 melanoma Baseline expression of PD-L1 by melanoma cell lines was virtually nil, regardles... BeFree 25370533 Detail
0.014 melanoma Serum samples from 275 high-risk melanoma patients enrolled in the Nordic Adjuva... BeFree 25832001 Detail
<0.001 Mesothelioma NA BeFree Detail
0.001 mitral valve stenosis NA BeFree Detail
0.003 multiple myeloma NA BeFree Detail
0.004 multiple sclerosis A multiple sclerosis-associated variant of CBLB links genetic risk with type I I... BeFree 25261476 Detail
<0.001 mumps Induction of IFN-α subtypes and their antiviral activity in mumps virus infectio... BeFree 25361048 Detail
<0.001 myasthenia gravis NA BeFree Detail
0.002 Mycobacterium Infections NA BeFree Detail
<0.001 Mycoses NA BeFree Detail
<0.001 Myeloproliferative disease NA BeFree Detail
<0.001 myocarditis NA BeFree Detail
<0.001 myositis NA BeFree Detail
<0.001 Nasal Polyps NA BeFree Detail
0.003 Neoplasm Metastasis Conversely, the IFN metagene was associated with a low risk of metastasis in 104... BeFree 24853384 Detail
0.003 Neoplasm Metastasis These results provide evidence supporting that EMT activation and IFN pathway in... BeFree 25001613 Detail
0.003 Neoplasm Metastasis Overall, our findings describe a novel role for IFN during metastasis developmen... BeFree 25604426 Detail
0.002 neuroblastoma Delayed IFN response differentiates replication of West Nile virus and Japanese ... BeFree 25920530 Detail
<0.001 neutropenia Logistic regression analysis showed that rs2305482 CC and neutrophil count at ba... BeFree 25515861 Detail
<0.001 obesity NA BeFree Detail
<0.001 Degenerative polyarthritis NA BeFree Detail
<0.001 osteomyelitis NA BeFree Detail
0.001 osteosarcoma NA BeFree Detail
0.001 ovarian carcinoma NA BeFree Detail
<0.001 papilloma NA BeFree Detail
<0.001 bullous pemphigoid NA BeFree Detail
<0.001 periodontitis NA BeFree Detail
<0.001 Peripheral neuropathy NA BeFree Detail
<0.001 Pituitary Neoplasms NA BeFree Detail
<0.001 plasmacytoma NA BeFree Detail
<0.001 Pneumococcal Infections NA BeFree Detail
0.002 polycythemia vera NA BeFree Detail
<0.001 Post-kala-azar dermal leishmaniasis Uniformly low expression of IFN and IFNGR1 in PKDL skin biopsies could explain p... BeFree 25466928 Detail
<0.001 progeria NA BeFree Detail
<0.001 Prostatic Neoplasms NA BeFree Detail
0.001 psoriasis In contrast, other antimicrobial peptides expressed in psoriatic skin including ... BeFree 25332209 Detail
<0.001 kidney failure NA BeFree Detail
0.003 Respiratory Syncytial Virus Infections Furthermore, knocking down the endogenous and IFN-induced expression of IFITM1 a... BeFree,GAD 25228491 Detail
<0.001 Respiratory Tract Infections NA BeFree Detail
<0.001 Retroviridae Infections NA BeFree Detail
<0.001 Rheumatism NA BeFree Detail
<0.001 RNA Virus Infections NA BeFree Detail
<0.001 Rotavirus Infections NA BeFree Detail
<0.001 sarcoidosis NA BeFree Detail
<0.001 Kaposi sarcoma NA BeFree Detail
<0.001 schistosomiasis NA BeFree Detail
0.002 systemic scleroderma Genotype-mRNA expression correlation analysis revealed that the IRF8 protective ... BeFree 25880423 Detail
<0.001 Skin lesion The fact that treatment with recombinant type I IFNs (α and β) can induce not on... BeFree 24420508 Detail
<0.001 Skin lesion In contrast, other antimicrobial peptides expressed in psoriatic skin including ... BeFree 25332209 Detail
<0.001 Skin Neoplasms Delivery of DNA vaccines encoding XBP1 and tumor Ag to skin DC resulted in incre... BeFree 25972487 Detail
<0.001 ankylosing spondylitis NA BeFree Detail
<0.001 Superinfection NA BeFree Detail
<0.001 Giant Cell Arteritis NA BeFree Detail
<0.001 tetanus NA BeFree Detail
<0.001 Thrombocythemia, Essential NA BeFree Detail
<0.001 thyroiditis NA BeFree Detail
<0.001 thyrotoxicosis NA BeFree Detail
<0.001 Trisomy NA BeFree Detail
<0.001 Chagas disease NA BeFree Detail
<0.001 tuberculosis NA BeFree Detail
<0.001 uveitis NA BeFree Detail
<0.001 viral hepatitis NA BeFree Detail
0.001 Viremia NA BeFree Detail
<0.001 vitiligo NA BeFree Detail
<0.001 Wiskott-Aldrich syndrome NA BeFree Detail
<0.001 yellow fever Here we show that yellow fever virus (YFV) inhibits IFN-I signaling through a un... BeFree 25211074 Detail
<0.001 Fibromatosis, Aggressive NA BeFree Detail
<0.001 B-Cell Lymphomas NA BeFree Detail
<0.001 diffuse large B-cell lymphoma In DLBCL cell lines, CC-122-induced degradation or short hairpin RNA-mediated kn... BeFree 26002965 Detail
<0.001 T-Cell Lymphoma NA BeFree Detail
<0.001 Lymphoma, T-Cell, Cutaneous NA BeFree Detail
<0.001 severe combined immunodeficiency NA BeFree Detail
<0.001 Li-Fraumeni syndrome NA BeFree Detail
<0.001 Encephalopathies Aicardi-Goutières syndrome (AGS) is an autosomal-recessive encephalopathy in chi... BeFree 25500879 Detail
<0.001 Encephalopathies In humans, loss of function mutations in the SAMHD1 (AGS5) gene cause a severe f... BeFree 25672750 Detail
<0.001 acute leukemia NA BeFree Detail
<0.001 Polyglandular Type I Autoimmune Syndrome NA BeFree Detail
<0.001 Depressive Symptoms NA BeFree Detail
<0.001 Small cell carcinoma of lung NA BeFree Detail
<0.001 Cutaneous Melanoma NA BeFree Detail
<0.001 Idiopathic pulmonary hypertension NA BeFree Detail
<0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 allergic asthma NA BeFree Detail
<0.001 intrinsic asthma NA BeFree Detail
<0.001 Right Ventricular Hypertrophy NA BeFree Detail
<0.001 Cicatrix, Hypertrophic NA BeFree Detail
<0.001 Tumor Progression NA BeFree Detail
<0.001 Diabetes, Autoimmune NA BeFree Detail
<0.001 Dysplastic Nevus NA BeFree Detail
<0.001 Lung Diseases, Interstitial NA BeFree Detail
<0.001 Idiopathic hypereosinophilic syndrome NA BeFree Detail
<0.001 Cervical Intraepithelial Neoplasia The objective of this study was to evaluate the production of cytokines in helpe... BeFree 25764160 Detail
<0.001 Rhabdoid Tumor NA BeFree Detail
<0.001 uveal melanoma NA BeFree Detail
0.001 Adult type dermatomyositis NA BeFree Detail
<0.001 Paresthesia, Distal NA BeFree Detail
0.002 pancreatic carcinoma Human pancreatic cancer cell lines variably respond to IFN-α and -β. BeFree 24460759 Detail
0.002 pancreatic carcinoma A few years ago in vitro, in vivo, and several clinical trials have been describ... BeFree 25551196 Detail
<0.001 Female Pseudohermaphroditism NA BeFree Detail
<0.001 Anemia, severe NA BeFree Detail
<0.001 Fibrosis, Liver NA BeFree Detail
<0.001 Hepatitis, Autoimmune NA BeFree Detail
0.001 Malignant neoplasm of lung NA BeFree Detail
0.031 Hepatitis C, Chronic The SNPs rs738409478 and rs2645424 were determined by real-time PCR in 478 patie... BeFree 23870067 Detail
<0.001 Drug usage NA BeFree Detail
<0.001 Parasitemia NA BeFree Detail
<0.001 viral encephalitis NA BeFree Detail
<0.001 disseminated eosinophilic collagen disease NA BeFree Detail
0.002 Vesicular Stomatitis In transfected bovine fetal fibroblasts, expression of intracellular IFN-α induc... BeFree 25004008 Detail
0.002 Vesicular Stomatitis Since pDC, but not cDC, from pearl mice showed an impaired IFN-α and tumor necro... BeFree 25333950 Detail
0.002 Vesicular Stomatitis Therefore, IFN-α and -β differentially affect VSV oncolysis, justifying the eval... BeFree 25995245 Detail
0.002 Vesicular Stomatitis We found that TLR3-ligand polyinosinic-polycytidylic acid and human rhinovirus i... BeFree 26101320 Detail
0.003 Coinfection The OPERA study results show that PEG-IFN plus ribavirin is an effective treatme... BeFree 24583976 Detail
<0.001 Viral myocarditis NA BeFree Detail
<0.001 Herpes encephalitis NA BeFree Detail
<0.001 Disease due to Parvoviridae Pancreatic adenocarcinoma upregulated factor (PAUF) confers resistance to pancre... BeFree 25727013 Detail
0.002 Respiratory syncytial virus bronchiolitis NA GAD Detail
0.001 Chronic viral hepatitis The induction of TLR7 responsiveness of monocytes by IFNα in vivo in HCV patient... BeFree 25014880 Detail
<0.001 Metastatic Renal Cell Cancer NA BeFree Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
<0.001 Philadelphia chromosome positive chronic myelogenous leukemia NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus NA BeFree Detail
<0.001 Transitional cell carcinoma of bladder NA BeFree Detail
<0.001 Solid tumour NA BeFree Detail
<0.001 Adenocarcinoma of pancreas NA BeFree Detail
<0.001 Iron Overload NA BeFree Detail
<0.001 Tumor necrosis NA BeFree Detail
<0.001 Adenocarcinoma of colon NA BeFree Detail
<0.001 Impaired cognition NA BeFree Detail
<0.001 Stable angina NA BeFree Detail
<0.001 Chronic liver disease Of 326 patients with HCV-related chronic liver disease (252 with genotype 1b and... BeFree 24065124 Detail
<0.001 Specific viral infections NA BeFree Detail
<0.001 Malignant neoplasm of liver NA BeFree Detail
<0.001 malignant mesothelioma NA BeFree Detail
<0.001 chronic eosinophilic leukemia NA BeFree Detail
0.002 Malignant neoplasm of pancreas Human pancreatic cancer cell lines variably respond to IFN-α and -β. BeFree 24460759 Detail
0.002 Malignant neoplasm of pancreas A few years ago in vitro, in vivo, and several clinical trials have been describ... BeFree 25551196 Detail
<0.001 Asthma attack Additionally, individuals with asthma who are infected with HCV and respond to I... BeFree 26026068 Detail
<0.001 Malignant neoplasm of central nervous system NA BeFree Detail
<0.001 Cervical intraepithelial neoplasia grade 2 We conducted a prospective study with 17 patients with CIN II-III using immunoth... BeFree 25764160 Detail
<0.001 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
0.002 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site Viral non-structural proteins NS1 and NS2 are critically required for RSV virule... BeFree 24992002 Detail
0.002 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site In order to explore the interactions between the IFN pathway and human respirato... BeFree 25228491 Detail
<0.001 dengue shock syndrome NA BeFree Detail
0.001 Malignant neoplasm of prostate Additional studies will be required to fully establish the cross-talk between an... BeFree 25327819 Detail
<0.001 Hematologic Neoplasms NA BeFree Detail
<0.001 Aicardi-Goutieres syndrome In humans, loss of function mutations in the SAMHD1 (AGS5) gene cause a severe f... BeFree 25672750 Detail
<0.001 thrombophilia NA BeFree Detail
0.007 lupus erythematosus The fact that treatment with recombinant type I IFNs (α and β) can induce not on... BeFree 24420508 Detail
0.007 lupus erythematosus Persistent production of IFN-α, the most abundant subtype measured in these pati... BeFree 25468480 Detail
<0.001 Disseminated due to other mycobacteria NA BeFree Detail
<0.001 Chronic active hepatitis NA BeFree Detail
0.008 Hepatitis B, Chronic Peginterferon α (PEG-IFN), which includes PEG-IFN α-2a (Pegasys) and PEG-IFN α-2... BeFree 24738850 Detail
0.008 Hepatitis B, Chronic We retrospectively enrolled 190 patients with chronic hepatitis B HBeAg negative... BeFree 25060765 Detail
0.008 Hepatitis B, Chronic Indeed, IFN-α has been successfully used for treatment of patients with chronic ... BeFree 25206268 Detail
0.008 Hepatitis B, Chronic Here, a study was conducted to investigate the dynamic changes in phenotype and ... BeFree 25774808 Detail
<0.001 Mixed cryoglobulinemia Role of IL28B genotyping in patients with hepatitis C virus-associated mixed cry... BeFree 26060059 Detail
<0.001 Malignant neoplasm of esophagus NA BeFree Detail
<0.001 Thyroid carcinoma NA BeFree Detail
<0.001 Malignant epithelioma NA BeFree Detail
0.001 Malignant glioma IFN-DC of patients with malignant gliomas were characterized by low chemotaxis i... BeFree 25894778 Detail
0.001 Osteosarcoma of bone NA BeFree Detail
<0.001 Carcinogenesis NA BeFree Detail
0.001 prostate carcinoma Additional studies will be required to fully establish the cross-talk between an... BeFree 25327819 Detail
<0.001 Epithelial ovarian cancer NA BeFree Detail
0.003 breast carcinoma NA BeFree Detail
0.001 Carcinoma of lung NA BeFree Detail
0.002 colon carcinoma NA BeFree Detail
<0.001 stomach carcinoma NA BeFree Detail
0.002 Carcinoma of bladder NA BeFree Detail
0.002 Central neuroblastoma Delayed IFN response differentiates replication of West Nile virus and Japanese ... BeFree 25920530 Detail
<0.001 Varicella zoster Conversely, VZV infection in keratinocytes (HaCaT) resulted in a persistent incr... BeFree 26072679 Detail
<0.001 Malignant neoplasm of kidney NA BeFree Detail
<0.001 AIDS defining illness After multivariate analyses the independent positive predictors for SVR after tr... BeFree 25181403 Detail
<0.001 Multiple Sclerosis, Relapsing-Remitting NA BeFree Detail
0.001 Aicardi-Goutieres syndrome 1 Aicardi-Goutières syndrome (AGS) is an autosomal-recessive encephalopathy in chi... BeFree 25500879 Detail
0.001 Aicardi-Goutieres syndrome 1 In humans, loss of function mutations in the SAMHD1 (AGS5) gene cause a severe f... BeFree 25672750 Detail
<0.001 malignant pleural mesothelioma NA BeFree Detail
<0.001 thrombocytosis NA BeFree Detail
<0.001 Myocarditis, chronic NA BeFree Detail
<0.001 Acute coronary syndrome NA BeFree Detail
<0.001 Primary infection NOS NA BeFree Detail
<0.001 Ovarian adenocarcinoma NA BeFree Detail
<0.001 Colorectal cancer metastatic NA BeFree Detail
<0.001 Spondylarthritis NA BeFree Detail
<0.001 West Nile viral infection Delayed IFN response differentiates replication of West Nile virus and Japanese ... BeFree 25920530 Detail
<0.001 Malignant neoplasm of ovary NA BeFree Detail
<0.001 Primary HIV infection NA BeFree Detail
<0.001 Squamous cell carcinoma of the head and neck Differential responsiveness of tumor cells to IFN-α and -β was further supported... BeFree 25995245 Detail
0.002 severe acute respiratory syndrome Through our genomics-based approach, we found topological differences in the kin... BeFree 25534508 Detail
0.001 sarcoma NA BeFree Detail
<0.001 Persistent infection NA BeFree Detail
<0.001 Cutaneous lymphoma NA BeFree Detail
<0.001 Inflammatory disorder Finally, the broader role of IFN-λ in the immunopathogenesis of non-infectious i... BeFree 25634147 Detail
<0.001 Inflammatory disorder IFN-α production by plasmacytoid dendritic cell associations with polymorphisms ... BeFree 25779693 Detail
<0.001 Chronic myeloproliferative disorder In recent years, major molecular remissions have been observed in patients with ... BeFree 25082025 Detail
<0.001 Single tumor NA BeFree Detail
<0.001 Eosinophilic disorder NA BeFree Detail
<0.001 pancreatic ductal adenocarcinoma NA BeFree Detail
0.001 Carcinoma of urinary bladder, superficial NA BeFree Detail
<0.001 Treatment-Induced Anemia NA BeFree Detail
<0.001 Epithelioma NA BeFree Detail
<0.001 mature teratoma NA BeFree Detail
<0.001 renal carcinoma NA BeFree Detail
<0.001 Systemic onset juvenile chronic arthritis NA BeFree Detail
<0.001 Vascular lesions NA BeFree Detail
<0.001 Mammary Neoplasms NA BeFree Detail
<0.001 Primary Glioblastoma NA BeFree Detail
<0.001 Tumor Immunity In the present work, we hypothesized that engineering easily generated human mon... BeFree 25863943 Detail
<0.001 Xenograft Model NA BeFree Detail
<0.001 colorectal cancer NA BeFree Detail
<0.001 hypereosinophilic syndrome NA BeFree Detail
<0.001 Glioblastoma multiforme NA BeFree Detail
0.005 Cirrhosis Of 326 patients with HCV-related chronic liver disease (252 with genotype 1b and... BeFree 24065124 Detail
0.005 Cirrhosis The recent October 2014 approval of the fixed dose combination (FDC) of the NS5B... BeFree 25676581 Detail
<0.001 Disorder characterized by eosinophilia NA BeFree Detail
<0.001 tumor vasculature NA BeFree Detail
<0.001 Recurrent infections (sinusitis and bacterial pneumonia and meningitis) Thus, identification of these SNPs may be useful to predict the response to IFN-... BeFree 25938745 Detail
<0.001 VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) NA BeFree Detail
<0.001 Craniometaphyseal dysplasia, autosomal dominant NA BeFree Detail
<0.001 coronary artery disease The results argue against the potential utility of drugs targeting type-I IFN pr... BeFree 25882064 Detail
0.001 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree Detail
0.006 liver carcinoma Here, we report that the IFN-α-induced microRNA-26a (miR-26a) can inhibit HCC pr... BeFree 25494962 Detail
<0.001 Allergic rhinitis (disorder) NA BeFree Detail
<0.001 MYD88 Deficiency NA BeFree Detail
<0.001 Steatohepatitis Hepatic steatosis is a risk factor for both liver disease progression and an imp... BeFree 25961570 Detail
0.001 Nasopharyngeal carcinoma NA BeFree Detail
<0.001 Mechanical Allodynia NA BeFree Detail
<0.001 Tuberculous pleural effusion NA BeFree Detail
<0.001 Pulmonary arterial hypertension NA BeFree Detail
<0.001 FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) NA BeFree Detail
<0.001 Autoimmune polyendocrinopathy syndrome, type 1 NA BeFree Detail
<0.001 Allergic disposition NA BeFree Detail
<0.001 Allergic sensitization NA BeFree Detail
<0.001 Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia NA BeFree Detail
<0.001 Experimental Organism Basal Cell Carcinoma NA BeFree Detail
<0.001 adenocarcinoma NA BeFree Detail
<0.001 Adenovirus Infections NA BeFree Detail
<0.001 Primary myelofibrosis NA BeFree Detail
0.002 anemia Polymorphisms at the SLC29A1 gene, encoding ENT1, may influence ribavirin-associ... BeFree 25583751 Detail
<0.001 Angina, Unstable NA BeFree Detail
<0.001 Anorexia PEG-IFN/RBV/TVR therapy yielded high SVR rates, but it was associated with a dec... BeFree 25400176 Detail
0.001 arteriosclerosis Patients with systemic lupus erythematosus are genetically predisposed to enhanc... BeFree 25882064 Detail
0.001 arthritis NA BeFree Detail
0.002 rheumatoid arthritis NA BeFree Detail
0.005 asthma Multiple deficiencies in the innate immune response to HRV were identified in as... BeFree,GAD 25203745 Detail
0.005 asthma The role of macrophage IL-10/innate IFN interplay during virus-induced asthma. BeFree,GAD 25430775 Detail
0.005 asthma Rhinovirus infections are the dominant cause of asthma exacerbations, and defici... BeFree,GAD 25630941 Detail
0.005 asthma Additionally, individuals with asthma who are infected with HCV and respond to I... BeFree,GAD 26026068 Detail
0.001 atherosclerosis Patients with systemic lupus erythematosus are genetically predisposed to enhanc... BeFree 25882064 Detail
0.007 Autoimmune Diseases We investigated whether single-nucleotide polymorphisms (SNPs) associated with S... BeFree 25779693 Detail
0.007 Autoimmune Diseases Trex1 (-/-) mice develop lethal, IFN-driven autoimmune disease that is dependent... BeFree 26223655 Detail
<0.001 Melanoma, B16 NA BeFree Detail
<0.001 Behcet Syndrome NA BeFree Detail
<0.001 bipolar disorder As a result, IL-6, IL-8 and IFN related pathways held twice to thrice the number... BeFree 25855618 Detail
0.001 Malignant neoplasm of urinary bladder NA BeFree Detail
<0.001 Blast Phase NA BeFree Detail
<0.001 Blood Coagulation Disorders NA BeFree Detail
<0.001 Bone Diseases NA BeFree Detail
<0.001 Brain Neoplasms We compared migration activities of IFN-α- and IL-4-induced dendritic cells (IFN... BeFree 25894778 Detail
0.003 Malignant neoplasm of breast NA BeFree Detail
0.002 Bronchiolitis, Viral NA GAD Detail
<0.001 brucellosis NA BeFree Detail
<0.001 Burkitt lymphoma NA BeFree Detail
0.002 Malignant tumor of colon NA BeFree Detail
<0.001 Adenocarcinoma of prostate NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
<0.001 Non-small cell lung carcinoma NA BeFree Detail
0.003 renal cell carcinoma Gene therapy using this IFN-α2b gene construct with HREs may represent a novel t... BeFree 23739923 Detail
Annotation

Annotations

DescrptionSourceLinks
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The results argue against the potential utility of drugs targeting type-I IFN production for coronar... DisGeNET Detail
The results argue against the potential utility of drugs targeting type-I IFN production for coronar... DisGeNET Detail
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We showed that DC are the primary producers of type I interferons (T1-IFN), requisite cytokines for ... DisGeNET Detail
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Delayed IFN response differentiates replication of West Nile virus and Japanese encephalitis virus i... DisGeNET Detail
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Our results suggest that enterovirus-induced miR-146a facilitates viral pathogenesis by suppressing ... DisGeNET Detail
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Hepatic steatosis is a risk factor for both liver disease progression and an impaired response to in... DisGeNET Detail
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We have previously shown that cysteine-rich 61 protein (CCN1) activates a type 1 IFN antiviral defen... DisGeNET Detail
Delayed IFN response differentiates replication of West Nile virus and Japanese encephalitis virus i... DisGeNET Detail
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Those with mild HFMD had higher γ-IFN expression levels compared with those with severe HFMD (P < 0.... DisGeNET Detail
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The identification of mutations in the HVR1 region of hepatitis type C virus (HCV) is time-consuming... DisGeNET Detail
The identification of mutations in the HVR1 region of hepatitis type C virus (HCV) is time-consuming... DisGeNET Detail
For HBeAg-positive patients and HBeAg-negative patients with genotype D infection, PEG-IFN therapy c... DisGeNET Detail
The study of on-treatment dynamics of HBV infection by means of combined quantitative monitoring of ... DisGeNET Detail
Then, we aimed to investigate the role of CYP27B1 polymorphisms in HBV treatment with PEG-IFN. DisGeNET Detail
A total of 30 patients with CHB who achieved HBsAg seroclearance following peg-IFN-α therapy and an ... DisGeNET Detail
In SVR to Peg-IFN/NUCs MiR-B-Index improved during-therapy and post-treatment reaching IC-like value... DisGeNET Detail
A total of 210 patients with chronic hepatitis C genotype 1 of high viral load (baseline serum hepat... DisGeNET Detail
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The next phase of therapy will be combining several classes of DAAs without IFN in order to make sus... DisGeNET Detail
For patients infected with hepatitis C virus (HCV), the combination of the direct-acting antiviral a... DisGeNET Detail
In addition, the results suggest new viral genomic attributes that might influence the outcome of IF... DisGeNET Detail
Noncirrhotic HCV treatment-naive patients and prior relapsers received response-guided therapy (RGT)... DisGeNET Detail
Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection. DisGeNET Detail
In May 2011, boceprevir and telaprevir, two first-generation NS3/4A protease inhibitors, were approv... DisGeNET Detail
Treatment of hepatitis C virus (HCV) with pegylated interferon and ribavirin (IFN/RBV) can be associ... DisGeNET Detail
This review will focus on the second-wave DAAs including protease inhibitors (PI), nucleotide inhibi... DisGeNET Detail
Forty patients infected with hepatitis C virus (HCV) genotype 1 and starting anti-HCV therapy with t... DisGeNET Detail
Pegylated IFN-α-2a and ribavirin in the treatment of hepatitis C infection in children. DisGeNET Detail
Impaired induction of IL28B, related to IFNλ4 expression in PBMCs of IL28B-unfavorable patients, is ... DisGeNET Detail
Here, we discuss IFN-λ genetic polymorphisms and their role in HCV and other infectious diseases as ... DisGeNET Detail
IFN-free regimens with direct antiviral agents (DAAs) against hepatitis C virus (HCV) are likely to ... DisGeNET Detail
Peg-IFN and ribavirin treatment for recurrence of genotype 2 and 3 hepatitis C after liver transplan... DisGeNET Detail
In this contest IFN-α therapy, a standard therapy for HCV-infection and lymphoproliferative diseases... DisGeNET Detail
These findings expand our understanding of IFN-responses in HCV-infected individuals and suggest tha... DisGeNET Detail
We conducted an open-label trial to assess the efficacy and safety of sofosbuvir (SOF) plus pegylate... DisGeNET Detail
Between January 2006 and June 2012, a total of 180 patients with chronic infections of G2 hepatitis ... DisGeNET Detail
A total of 210 patients with chronic hepatitis C genotype 1 of high viral load (baseline serum hepat... DisGeNET Detail
Hepatitis C virus (HCV) genotype 1 infections are significantly more difficult to eradicate with PEG... DisGeNET Detail
To assess the accuracy and cost-effectiveness of the automated Abbott ARCHITECT HCV Ag assay (Wiesba... DisGeNET Detail
We demonstrated a marked polarization of NK cells toward cytotoxicity in response to IFN-α stimulati... DisGeNET Detail
Role of IL28B genotyping in patients with hepatitis C virus-associated mixed cryoglobulinemia and re... DisGeNET Detail
Sixty-one patients under suppressive antiretroviral therapy were included: 37 with hepatitis C virus... DisGeNET Detail
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The OPERA study results show that PEG-IFN plus ribavirin is an effective treatment for HCV-HIV coinf... DisGeNET Detail
We modeled increased activation in HIV infection by priming human monocytes with IFNα followed by ex... DisGeNET Detail
To determine SVR and other response rates, identify SVR predictors and analyse differences between G... DisGeNET Detail
The specific reduction of miR-422a is associated with exogenous IFN-α treatment, and likely contribu... DisGeNET Detail
In sum, we identified a novel mechanism of HIV-1-induced CXCL13 secretion-one caused by TLR7 inducti... DisGeNET Detail
Blimp-1 binds an IFN-stimulated response element within HIV-1 provirus, and it is displaced followin... DisGeNET Detail
The results suggest that the presence of the IFN+874A allele confers susceptibility to HIV-1 infecti... DisGeNET Detail
Group 1 comprised HIV/HCV co-infected patients who were treated with highly active antiretroviral th... DisGeNET Detail
These novel findings will be of great interest to those working on the roles of IFN and pDCs in HIV-... DisGeNET Detail
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The increased level of IFN-λ mRNA corresponded to significantly increased level of RIG-1 mRNA. shRNA... DisGeNET Detail
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Logistic regression analysis showed that rs2305482 CC and neutrophil count at baseline were independ... DisGeNET Detail
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Of 326 patients with HCV-related chronic liver disease (252 with genotype 1b and 74 with genotype 2a... DisGeNET Detail
The recent October 2014 approval of the fixed dose combination (FDC) of the NS5B polymerase inhibito... DisGeNET Detail
Hepatic steatosis is a risk factor for both liver disease progression and an impaired response to in... DisGeNET Detail
NA DisGeNET Detail
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Persistent production of IFN-α, the most abundant subtype measured in these patients, is an importan... DisGeNET Detail
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Persistent production of IFN-α, the most abundant subtype measured in these patients, is an importan... DisGeNET Detail
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RST1 isolates, which are more frequently associated with disseminated Lyme disease in humans and mic... DisGeNET Detail
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In this contest IFN-α therapy, a standard therapy for HCV-infection and lymphoproliferative diseases... DisGeNET Detail
Interferon-γ (IFNG) microsatellite repeat and single nucleotide polymorphism haplotypes of IFN-α rec... DisGeNET Detail
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Expression of the IFITM proteins was found to delay the phosphorylation of IFN regulatory factor 3 t... DisGeNET Detail
Baseline expression of PD-L1 by melanoma cell lines was virtually nil, regardless of BRAFmut status,... DisGeNET Detail
Serum samples from 275 high-risk melanoma patients enrolled in the Nordic Adjuvant IFN Melanoma tria... DisGeNET Detail
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A multiple sclerosis-associated variant of CBLB links genetic risk with type I IFN function. DisGeNET Detail
Induction of IFN-α subtypes and their antiviral activity in mumps virus infection. DisGeNET Detail
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Conversely, the IFN metagene was associated with a low risk of metastasis in 104 ERBB2+ tumors (P = ... DisGeNET Detail
These results provide evidence supporting that EMT activation and IFN pathway inactivation are marke... DisGeNET Detail
Overall, our findings describe a novel role for IFN during metastasis development and suggest that n... DisGeNET Detail
Delayed IFN response differentiates replication of West Nile virus and Japanese encephalitis virus i... DisGeNET Detail
Logistic regression analysis showed that rs2305482 CC and neutrophil count at baseline were independ... DisGeNET Detail
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Uniformly low expression of IFN and IFNGR1 in PKDL skin biopsies could explain parasite persistence ... DisGeNET Detail
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In contrast, other antimicrobial peptides expressed in psoriatic skin including elafin, hBD1, and ps... DisGeNET Detail
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Furthermore, knocking down the endogenous and IFN-induced expression of IFITM1 and 3 facilitated RSV... DisGeNET Detail
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Genotype-mRNA expression correlation analysis revealed that the IRF8 protective allele was associate... DisGeNET Detail
The fact that treatment with recombinant type I IFNs (α and β) can induce not only systemic organ ma... DisGeNET Detail
In contrast, other antimicrobial peptides expressed in psoriatic skin including elafin, hBD1, and ps... DisGeNET Detail
Delivery of DNA vaccines encoding XBP1 and tumor Ag to skin DC resulted in increased IFN-α productio... DisGeNET Detail
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Here we show that yellow fever virus (YFV) inhibits IFN-I signaling through a unique mechanism that ... DisGeNET Detail
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In DLBCL cell lines, CC-122-induced degradation or short hairpin RNA-mediated knockdown of Aiolos an... DisGeNET Detail
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Aicardi-Goutières syndrome (AGS) is an autosomal-recessive encephalopathy in children that is charac... DisGeNET Detail
In humans, loss of function mutations in the SAMHD1 (AGS5) gene cause a severe form of Aicardi-Gouti... DisGeNET Detail
NA DisGeNET Detail
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The objective of this study was to evaluate the production of cytokines in helper T (CD4+) lymphocyt... DisGeNET Detail
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Human pancreatic cancer cell lines variably respond to IFN-α and -β. DisGeNET Detail
A few years ago in vitro, in vivo, and several clinical trials have been described regarding adjuvan... DisGeNET Detail
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The SNPs rs738409478 and rs2645424 were determined by real-time PCR in 478 patients with CHC (m/f: 3... DisGeNET Detail
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In transfected bovine fetal fibroblasts, expression of intracellular IFN-α induced resistance to ves... DisGeNET Detail
Since pDC, but not cDC, from pearl mice showed an impaired IFN-α and tumor necrosis factor-α product... DisGeNET Detail
Therefore, IFN-α and -β differentially affect VSV oncolysis, justifying the evaluation and compariso... DisGeNET Detail
We found that TLR3-ligand polyinosinic-polycytidylic acid and human rhinovirus infection induced a p... DisGeNET Detail
The OPERA study results show that PEG-IFN plus ribavirin is an effective treatment for HCV-HIV coinf... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Pancreatic adenocarcinoma upregulated factor (PAUF) confers resistance to pancreatic cancer cells ag... DisGeNET Detail
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The induction of TLR7 responsiveness of monocytes by IFNα in vivo in HCV patients is relevant for th... DisGeNET Detail
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Of 326 patients with HCV-related chronic liver disease (252 with genotype 1b and 74 with genotype 2a... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Human pancreatic cancer cell lines variably respond to IFN-α and -β. DisGeNET Detail
A few years ago in vitro, in vivo, and several clinical trials have been described regarding adjuvan... DisGeNET Detail
Additionally, individuals with asthma who are infected with HCV and respond to IFN therapy showed a ... DisGeNET Detail
NA DisGeNET Detail
We conducted a prospective study with 17 patients with CIN II-III using immunotherapy with pegylated... DisGeNET Detail
NA DisGeNET Detail
Viral non-structural proteins NS1 and NS2 are critically required for RSV virulence; they strongly s... DisGeNET Detail
In order to explore the interactions between the IFN pathway and human respiratory syncytial virus (... DisGeNET Detail
NA DisGeNET Detail
Additional studies will be required to fully establish the cross-talk between androgen receptor-IFN ... DisGeNET Detail
NA DisGeNET Detail
In humans, loss of function mutations in the SAMHD1 (AGS5) gene cause a severe form of Aicardi-Gouti... DisGeNET Detail
NA DisGeNET Detail
The fact that treatment with recombinant type I IFNs (α and β) can induce not only systemic organ ma... DisGeNET Detail
Persistent production of IFN-α, the most abundant subtype measured in these patients, is an importan... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Peginterferon α (PEG-IFN), which includes PEG-IFN α-2a (Pegasys) and PEG-IFN α-2b (Peg-Intron), can ... DisGeNET Detail
We retrospectively enrolled 190 patients with chronic hepatitis B HBeAg negative treated for 48 week... DisGeNET Detail
Indeed, IFN-α has been successfully used for treatment of patients with chronic hepatitis B. DisGeNET Detail
Here, a study was conducted to investigate the dynamic changes in phenotype and function of peripher... DisGeNET Detail
Role of IL28B genotyping in patients with hepatitis C virus-associated mixed cryoglobulinemia and re... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
IFN-DC of patients with malignant gliomas were characterized by low chemotaxis in response to CCL19 ... DisGeNET Detail
NA DisGeNET Detail
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Additional studies will be required to fully establish the cross-talk between androgen receptor-IFN ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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Delayed IFN response differentiates replication of West Nile virus and Japanese encephalitis virus i... DisGeNET Detail
Conversely, VZV infection in keratinocytes (HaCaT) resulted in a persistent increase in type I IFN g... DisGeNET Detail
NA DisGeNET Detail
After multivariate analyses the independent positive predictors for SVR after treatment for chronic ... DisGeNET Detail
NA DisGeNET Detail
Aicardi-Goutières syndrome (AGS) is an autosomal-recessive encephalopathy in children that is charac... DisGeNET Detail
In humans, loss of function mutations in the SAMHD1 (AGS5) gene cause a severe form of Aicardi-Gouti... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Delayed IFN response differentiates replication of West Nile virus and Japanese encephalitis virus i... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Differential responsiveness of tumor cells to IFN-α and -β was further supported by the finding that... DisGeNET Detail
Through our genomics-based approach, we found topological differences in the kinetics and magnitude ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Finally, the broader role of IFN-λ in the immunopathogenesis of non-infectious inflammatory diseases... DisGeNET Detail
IFN-α production by plasmacytoid dendritic cell associations with polymorphisms in gene loci related... DisGeNET Detail
In recent years, major molecular remissions have been observed in patients with JAK2-positive chroni... DisGeNET Detail
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In the present work, we hypothesized that engineering easily generated human monocyte-derived mature... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Of 326 patients with HCV-related chronic liver disease (252 with genotype 1b and 74 with genotype 2a... DisGeNET Detail
The recent October 2014 approval of the fixed dose combination (FDC) of the NS5B polymerase inhibito... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Thus, identification of these SNPs may be useful to predict the response to IFN-based therapy of HCV... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The results argue against the potential utility of drugs targeting type-I IFN production for coronar... DisGeNET Detail
NA DisGeNET Detail
Here, we report that the IFN-α-induced microRNA-26a (miR-26a) can inhibit HCC proliferation and inva... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Hepatic steatosis is a risk factor for both liver disease progression and an impaired response to in... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Polymorphisms at the SLC29A1 gene, encoding ENT1, may influence ribavirin-associated anaemia, which ... DisGeNET Detail
NA DisGeNET Detail
PEG-IFN/RBV/TVR therapy yielded high SVR rates, but it was associated with a decreased body weight d... DisGeNET Detail
Patients with systemic lupus erythematosus are genetically predisposed to enhanced production of the... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Multiple deficiencies in the innate immune response to HRV were identified in asthma, with significa... DisGeNET Detail
The role of macrophage IL-10/innate IFN interplay during virus-induced asthma. DisGeNET Detail
Rhinovirus infections are the dominant cause of asthma exacerbations, and deficient virus induction ... DisGeNET Detail
Additionally, individuals with asthma who are infected with HCV and respond to IFN therapy showed a ... DisGeNET Detail
Patients with systemic lupus erythematosus are genetically predisposed to enhanced production of the... DisGeNET Detail
We investigated whether single-nucleotide polymorphisms (SNPs) associated with SLE and other autoimm... DisGeNET Detail
Trex1 (-/-) mice develop lethal, IFN-driven autoimmune disease that is dependent on activation of th... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
As a result, IL-6, IL-8 and IFN related pathways held twice to thrice the number of expected variant... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We compared migration activities of IFN-α- and IL-4-induced dendritic cells (IFN-DC and IL4-DC) gene... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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Gene therapy using this IFN-α2b gene construct with HREs may represent a novel treatment modality fo... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs738409478 dbSNP
Genome
hg38
Position
chr9:21,367,372-21,368,057
Variant Type
snv
Genome browser