Annotation Detail

Information
Associated Genes
IFNA13
Associated Variants
IFNA13 MUTATION
IFNA13 MUTATION
Associated Disease
Chronic viral hepatitis
Source Database
DisGeNET
Description
The induction of TLR7 responsiveness of monocytes by IFNα in vivo in HCV patients is relevant for the development of TLR7 agonists that are currently under development as a promising immunotherapeutic compounds to treat chronic viral hepatitis.
Pubmed
25014880
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs