Annotation Detail

Information
Associated Genes
IFNA13
Associated Variants
IFNA13 MUTATION
IFNA13 MUTATION
Associated Disease
melanoma
Source Database
DisGeNET
Description
Expression of the IFITM proteins was found to delay the phosphorylation of IFN regulatory factor 3 through interfering with the detection of viral RNA by MDA5 (melanoma differentiation-associated gene 5) and RIG-I (retinoic acid-inducible gene I).
Pubmed
25228491
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0135720936040152
Drugs