Annotation Detail

Information
Associated Genes
IFNA13
Associated Variants
IFNA13 MUTATION
IFNA13 MUTATION
Associated Disease
yellow fever
Source Database
DisGeNET
Description
Here we show that yellow fever virus (YFV) inhibits IFN-I signaling through a unique mechanism that involves binding of YFV NS5 to the IFN-activated transcription factor STAT2 only in cells that have been stimulated with IFN-I.
Pubmed
25211074
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
3
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs