Annotation Detail

Information
Associated Genes
IFNA13
Associated Variants
IFNA13 MUTATION
IFNA13 MUTATION
Associated Disease
Autoimmune Diseases
Source Database
DisGeNET
Description
Trex1 (-/-) mice develop lethal, IFN-driven autoimmune disease that is dependent on activation of the ISD pathway, but the DNA sensors that detect the endogenous DNA that accumulates in Trex1 (-/-) mice have not been defined.
Pubmed
26223655
Section of the abstract supporting the evidence
ALL_TEXT_2/3
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
4
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00678604680200758
Drugs