Annotation Detail
Information
- Associated Genes
- IFNA13
- Associated Variants
-
IFNA13 MUTATION
IFNA13 MUTATION - Associated Disease
- Lupus Erythematosus, Discoid
- Source Database
- DisGeNET
- Description
- Persistent production of IFN-α, the most abundant subtype measured in these patients, is an important feature of the immunopathogenesis of lupus and has stimulated current efforts to develop and test therapeutics that either block IFN-I or its receptor directly or target components of the IFN-I pathway involved in induction of or response to IFN-I.
- Pubmed
- 25468480
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 2
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00624316305784698
Drugs