dengue shock syndrome

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Information
Disease name
dengue shock syndrome
Disease ID
DOID:0050125
Description
"A dengue disease that involves the most severe form of dengue fever, has_material_basis_in Dengue virus [NCBITaxon:12637] with four serotypes (Dengue virus 1, 2, 3 and 4), which are transmitted_by Aedes mosquito bite. The infection has_symptom easy bruising, has_symptom blood spots, has_symptom bleeding gums, and has_symptom nosebleeds. It is accompanied by circulatory collapse, involves hypotension, narrow pulse pressure (less than or equal to 20mm Hg), or frank shock. The shock occurs after two to six days of symptoms, followed by collapse, weak pulse, and blueness around the mouth." [url:http\://en.wikipedia.org/wiki/Dengue_shock_syndrome]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00468858 Completed Phase 2 A Study of Two Doses of WRAIR Dengue Vaccine Administered Six Months Apart to Healthy Adults and Children July 2007 April 2010
NCT00919178 Completed Phase 1 Safety of and Immune Response to DEN4 Vaccine Component Candidate for Dengue Virus July 2009 May 2010
NCT04048837 Completed Prospective Study for the Evaluation of Dengue Prognostic Biomarkers in Singapore July 30, 2018 July 1, 2019
NCT04673422 Completed Phase 2/Phase 3 Effect of Montelukast in Preventing Dengue With Warning Signs in Dengue Patients January 15, 2021 June 17, 2023
NCT04837430 Recruiting NT-proBNP and Troponin I in Dengue Children April 2, 2021 December 31, 2023
NCT00966628 Unknown status Phase 3 Effect of Hypertonic Sodium Lactate on sVCAM-1 Level as Surrogate Marker of Endothelial Capillary Leakage in Pediatric Dengue Shock Syndrome Patients (DSS) May 2008 December 2009
Disase is a (Disease Ontology)
DOID:12205
Exact Synonym (Disease Ontology)
DSS
MedGen concept unique identifier (MedGen Concept name)
C0376300
MedGen unique identifier (MedGen Concept name)
83958