chr5:140631728:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr5:140,011,313-140,013,285 
hg38 chr5:140,631,728-140,633,700

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.006 Cardiovascular Diseases Psoriasis patients exhibit an increased risk of death by cardiovascular disease ... BeFree,GAD 26223654 Detail
<0.001 carotid stenosis NA BeFree Detail
0.006 celiac disease NA BeFree,GAD,LHGDN Detail
0.002 brain ischemia NA GAD Detail
0.002 Cerebrovascular Disorders NA GAD Detail
0.003 Chlamydia Infections NA BeFree,GAD Detail
<0.001 choledochal cyst NA BeFree Detail
0.085 cholestasis NA BeFree,GAD,LHGDN,RGD Detail
0.002 chorioamnionitis NA GAD Detail
0.031 ulcerative colitis NA BeFree,GAD,LHGDN Detail
0.001 colorectal carcinoma GM-CSF or M-CSF-stimulated peripheral blood CD14(+) cells from healthy donors we... BeFree 24737547 Detail
0.003 Colorectal Neoplasms NA LHGDN Detail
<0.001 common variable immunodeficiency NA BeFree Detail
0.002 Connective Tissue Diseases NA GAD Detail
0.015 Coronary Arteriosclerosis Moreover, we observed that the level of miR-155 expression was up-regulated in C... BeFree,GAD 24675724 Detail
0.015 Coronary Arteriosclerosis The number of circulating CD14(+)CD16(+) monocytes is increased in patients with... BeFree,GAD 25134759 Detail
0.005 Coronary heart disease Moreover, we observed that the level of miR-155 expression was up-regulated in C... BeFree 24675724 Detail
0.005 Coronary heart disease The number of circulating CD14(+)CD16(+) monocytes is increased in patients with... BeFree 25134759 Detail
0.031 Crohn Disease Although CD14 macrophages augment intestinal inflammation in patients with CD, m... BeFree,GAD,LHGDN 24991784 Detail
0.005 cystic fibrosis NA BeFree,GAD Detail
0.002 Cytomegalovirus Infections NA GAD Detail
0.003 Cessation of life NA LHGDN Detail
<0.001 dental caries NA BeFree Detail
0.006 Dermatitis, Atopic NA BeFree,GAD,LHGDN Detail
0.009 Diabetes Mellitus, Insulin-Dependent NA BeFree,GAD,LHGDN Detail
0.008 Diabetes Mellitus, Non-Insulin-Dependent Bezafibrate, a peroxisome proliferator-activated receptor α agonist, decreases c... BeFree,GAD,LHGDN 25134759 Detail
0.120 diarrhea NA BeFree,CTD_human Detail
<0.001 dysgerminoma NA BeFree Detail
0.002 Dyspepsia NA GAD Detail
0.122 Eczema NA BeFree,CTD_human Detail
0.002 Enterovirus Infections NA GAD Detail
0.002 erythema nodosum NA GAD Detail
<0.001 Fatigue NA BeFree Detail
0.002 Fetal Diseases NA GAD Detail
0.005 Fetal Membranes, Premature Rupture NA GAD Detail
0.003 Fibrosis NA LHGDN Detail
0.005 food allergy NA GAD,LHGDN Detail
0.003 gastritis NA BeFree,GAD Detail
<0.001 Giant Cell Tumors NA BeFree Detail
0.001 Gingival Diseases NA BeFree Detail
<0.001 glioblastoma NA BeFree Detail
0.002 glomerulonephritis NA GAD Detail
0.121 IgA glomerulonephritis Furthermore, the aberrant expansion of the (CD14(+)CD16(+)) subset could explain... BeFree,CTD_human 25770168 Detail
<0.001 gonorrhea NA BeFree Detail
0.120 gout NA CTD_human Detail
<0.001 Graft-vs-Host Disease NA BeFree Detail
<0.001 Graves Disease NA BeFree Detail
0.002 Hay fever NA GAD Detail
0.002 Heart failure NA GAD Detail
<0.001 hemangioma NA BeFree Detail
<0.001 Severe Dengue We demonstrate for the first time that augmented miR-150 expression with depress... BeFree 24907421 Detail
<0.001 hepatitis B NA BeFree Detail
0.003 hepatitis C NA BeFree,GAD Detail
<0.001 Herpes Simplex Infections NA BeFree Detail
0.002 Herpesviridae Infections NA GAD Detail
0.080 Hirschsprung Disease NA RGD Detail
<0.001 Histiocytosis, Langerhans-Cell NA BeFree Detail
<0.001 Malignant histiocytosis NA BeFree Detail
0.008 HIV Infections Maintenance of virologic efficacy and decrease in levels of β2-microglobulin, so... BeFree 25173576 Detail
0.008 HIV Infections Using our previously determined optimal cut-point of 45 copies/10 cells for this... BeFree 25232899 Detail
0.003 Hodgkin Disease NA BeFree,GAD Detail
<0.001 Hypercholesterolemia, Familial NA BeFree Detail
<0.001 Hyperlipidemia NA BeFree Detail
0.007 Hypersensitivity NA GAD,LHGDN Detail
0.010 Immediate hypersensitivity NA GAD,LHGDN Detail
0.017 Inflammation NA GAD Detail
0.012 Inflammatory Bowel Diseases NA BeFree,GAD,LHGDN Detail
0.002 ischemia NA GAD Detail
0.080 Jaundice, Obstructive NA RGD Detail
<0.001 arthropathy NA BeFree Detail
0.002 Kidney Diseases NA GAD Detail
0.003 Kidney Failure, Chronic The number of circulating CD14(+)CD16(+) monocytes is increased in patients with... BeFree,GAD 25134759 Detail
0.002 Premature Obstetric Labor NA GAD Detail
<0.001 leprosy NA BeFree Detail
0.002 leukemia NA BeFree Detail
0.001 chronic lymphocytic leukemia In chronic lymphocytic leukemia patients, nurse-like cells differentiate from CD... BeFree 25398834 Detail
0.004 Leukemia, Myelocytic, Acute CCAAT/enhancer-binding protein (C/EBP) β, which can bind to CD14 promoter and in... BeFree 25448741 Detail
<0.001 Myeloid Leukemia, Chronic NA BeFree Detail
<0.001 Leukemia, Myelomonocytic, Chronic NA BeFree Detail
0.003 acute promyelocytic leukemia NA BeFree,LHGDN Detail
0.127 liver cirrhosis NA BeFree,CTD_human,GAD Detail
0.003 Liver Cirrhosis, Alcoholic NA BeFree,GAD Detail
0.006 Liver diseases NA BeFree,GAD Detail
0.014 Alcoholic Liver Diseases NA BeFree,GAD,LHGDN Detail
0.003 Lung diseases NA BeFree,GAD Detail
0.003 Chronic Obstructive Airway Disease NA BeFree,GAD Detail
0.001 Lupus Erythematosus, Systemic Here, we report increased expression of TLR2 in CD4(+) and CD8(+) T cells, CD19(... BeFree 26079624 Detail
<0.001 Lyme disease NA BeFree Detail
0.003 lymphoma The percent of CD14(+) HLA-DR(low/-) monocytes was significantly higher in the l... BeFree,GAD 24636145 Detail
0.003 Lymphoma, Non-Hodgkin NA BeFree,GAD Detail
<0.001 malaria NA BeFree Detail
<0.001 Malaria, Falciparum NA BeFree Detail
0.005 Malignant neoplasm of stomach Association of CD14/-260 polymorphism with gastric cancer risk in Highland Tibet... BeFree,GAD 24627605 Detail
<0.001 paroxysmal nocturnal hemoglobinuria NA BeFree Detail
<0.001 melioidosis NA BeFree Detail
0.002 Meningeal Neoplasms NA GAD Detail
0.002 meningioma NA GAD Detail
<0.001 Mesothelioma NA BeFree Detail
<0.001 mitral valve stenosis NA BeFree Detail
0.003 Mucocutaneous Lymph Node Syndrome NA BeFree,GAD Detail
<0.001 multiple myeloma We found that LIGHT was overproduced by CD14+ monocytes, CD8+ T-cells and neutro... BeFree 25460501 Detail
0.003 Multiple Organ Failure NA LHGDN Detail
0.008 multiple sclerosis NA BeFree,GAD,LHGDN Detail
0.002 Musculoskeletal Diseases NA GAD Detail
0.018 myocardial infarction This elevation could represent evidence of monocyte dysfunction in psoriasis pat... BeFree,GAD,LHGDN 26223654 Detail
0.002 narcolepsy NA GAD Detail
0.002 Nasal obstruction present finding NA GAD Detail
<0.001 Nasal Polyps NA BeFree Detail
<0.001 Neoplasm Metastasis NA BeFree Detail
<0.001 nephroblastoma NA BeFree Detail
<0.001 nephrotic syndrome NA BeFree Detail
0.080 Neuritis, Autoimmune, Experimental NA RGD Detail
0.002 obesity Increased monocytic CD14⁺HLADRlow/- myeloid-derived suppressor cells in obesity. BeFree 25384365 Detail
<0.001 optic neuritis This massive B-cell-restricted initiation of the immune response in the early di... BeFree 25593026 Detail
<0.001 Degenerative polyarthritis NA BeFree Detail
<0.001 Osteoporosis, Postmenopausal NA BeFree Detail
0.003 otitis media NA BeFree,GAD Detail
<0.001 Pancreatic Diseases NA BeFree Detail
0.008 pancreatitis NA BeFree,GAD,LHGDN Detail
0.002 Parkinson disease NA GAD Detail
<0.001 periapical periodontitis Polymorphism of the CD14 and TLR4 genes and post-treatment apical periodontitis. BeFree 24461398 Detail
0.014 Periodontal Diseases NA BeFree,GAD,LHGDN Detail
0.002 Periodontal Pocket NA GAD Detail
0.099 periodontitis Further studies are needed to determine if reduced CD14 expression is linked to ... BeFree,GAD,RGD 25228314 Detail
0.003 Periodontitis, Juvenile NA BeFree,GAD Detail
<0.001 peritonitis NA BeFree Detail
<0.001 pituitary adenoma NA BeFree Detail
0.003 Pneumococcal Infections NA BeFree,GAD Detail
<0.001 pneumonia NA BeFree Detail
0.005 pre-eclampsia NA GAD Detail
0.002 Pregnancy Complications, Hematologic NA GAD Detail
0.002 Pregnancy Complications, Infectious NA GAD Detail
0.002 Prenatal Exposure Delayed Effects NA GAD Detail
<0.001 Prostatic Neoplasms NA BeFree Detail
<0.001 Prurigo NA BeFree Detail
0.002 Puerperal Disorders NA GAD Detail
<0.001 Respiration Disorders NA BeFree Detail
0.002 Respiratory Syncytial Virus Infections NA GAD Detail
<0.001 Respiratory Tract Diseases NA BeFree Detail
<0.001 Respiratory Tract Infections In infants with the TC + CC genotype of CD14, high levels of perinatal anxiety w... BeFree 25263840 Detail
0.007 rhinitis NA GAD,LHGDN Detail
0.003 Rhinitis, Allergic, Perennial NA BeFree,GAD Detail
0.014 sarcoidosis NA BeFree,GAD,LHGDN Detail
<0.001 Sarcoidosis, Pulmonary NA BeFree Detail
<0.001 schizophrenia NA BeFree Detail
<0.001 systemic scleroderma NA BeFree Detail
0.005 Septicemia The association of polymorphisms of TLR4 and CD14 genes with susceptibility to s... BeFree 25394369 Detail
0.005 Septicemia The complement system and the Toll-like (TLR) co-receptor CD14 play important ro... BeFree 26241501 Detail
0.005 Septic Shock NA GAD Detail
<0.001 Signs and Symptoms, Respiratory NA BeFree Detail
0.002 Dermatologic disorders NA GAD Detail
<0.001 ankylosing spondylitis NA BeFree Detail
<0.001 status asthmaticus NA BeFree Detail
0.007 Stomach Neoplasms NA GAD Detail
0.002 Streptococcal Infections NA GAD Detail
0.017 Cerebrovascular accident NA BeFree,GAD,LHGDN Detail
<0.001 synovitis NA BeFree Detail
0.005 thromboangiitis obliterans NA BeFree,GAD,LHGDN Detail
<0.001 Thrombocythemia, Essential NA BeFree Detail
0.002 thrombosis NA GAD Detail
0.002 toxoplasmosis NA GAD Detail
0.002 trachoma NA GAD Detail
0.013 tuberculosis The association between C-159T polymorphism in CD14 gene and susceptibility to t... BeFree,GAD,LHGDN 25091944 Detail
0.013 tuberculosis Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor ... BeFree,GAD,LHGDN 25275318 Detail
0.003 Tuberculosis, Pulmonary NA BeFree,GAD Detail
<0.001 Upper Respiratory Infections NA BeFree Detail
<0.001 Vascular Diseases NA BeFree Detail
<0.001 Virus Diseases NA BeFree Detail
0.001 Wheezing NA BeFree Detail
0.005 Helicobacter Infections NA GAD Detail
<0.001 B-Cell Lymphomas CD14(+) HLA-DR low/(-) monocytes as indicator of disease aggressiveness in B-cel... BeFree 24636145 Detail
<0.001 diffuse large B-cell lymphoma The percent of CD14(+) HLA-DR(low/-) monocytes was significantly higher in the l... BeFree 24636145 Detail
<0.001 Lymphoma, Large-Cell, Follicular NA BeFree Detail
<0.001 Peripheral Vascular Diseases NA BeFree Detail
<0.001 severe combined immunodeficiency NA BeFree Detail
0.006 Bronchial Hyperreactivity NA BeFree,GAD Detail
0.002 bacterial vaginosis NA GAD Detail
<0.001 Polyendocrinopathies, Autoimmune Blocking experiments with specific neutralizing antibodies for TLR1, TLR6, and C... BeFree 26195551 Detail
0.003 Gram-Negative Bacterial Infections NA BeFree,LHGDN Detail
<0.001 Meningitis, Bacterial NA BeFree Detail
<0.001 Monocytosis NA BeFree Detail
<0.001 Pancreatitis, Chronic NA BeFree Detail
<0.001 obstructive nephropathy NA BeFree Detail
<0.001 Genital ulceration NA BeFree Detail
0.009 Premature Birth NA GAD Detail
0.003 Myocardial Ischemia NA BeFree,GAD Detail
<0.001 Coronary Occlusion NA BeFree Detail
<0.001 Malignant neoplasm of mouth Association of TLR2, TLR3, TLR4 and CD14 genes polymorphisms with oral cancer ri... BeFree 23796347 Detail
0.006 acute myocardial infarction NA BeFree,GAD Detail
<0.001 Old myocardial infarction NA BeFree Detail
0.004 allergic asthma Association of CD14 C159T polymorphism with atopic asthma susceptibility in chil... BeFree 25966203 Detail
0.002 adrenoleukodystrophy NA BeFree Detail
0.080 Liver Failure, Acute NA BeFree,RGD Detail
<0.001 Agenesis of corpus callosum NA BeFree Detail
0.002 Periodontal Attachment Loss NA GAD Detail
0.003 Lichen Planus, Oral NA BeFree,LHGDN Detail
0.003 Community-Acquired Infections NA LHGDN Detail
<0.001 Giant Cell Tumor of Bone NA BeFree Detail
<0.001 Lip and oral cavity carcinoma Association of TLR2, TLR3, TLR4 and CD14 genes polymorphisms with oral cancer ri... BeFree 23796347 Detail
<0.001 X-linked agammaglobulinemia NA BeFree Detail
<0.001 Cerebral atrophy HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patient... BeFree 25232899 Detail
<0.001 pancreatic carcinoma NA BeFree Detail
<0.001 Inclusion Body Myositis (disorder) NA BeFree Detail
<0.001 Fibrosis, Liver NA BeFree Detail
0.002 coronary stenosis NA GAD Detail
0.005 Mucosa-Associated Lymphoid Tissue Lymphoma NA GAD,LHGDN Detail
0.005 Systemic Inflammatory Response Syndrome NA BeFree,GAD Detail
0.043 Sepsis The association of polymorphisms of TLR4 and CD14 genes with susceptibility to s... BeFree,GAD 25394369 Detail
0.043 Sepsis The complement system and the Toll-like (TLR) co-receptor CD14 play important ro... BeFree,GAD 26241501 Detail
<0.001 Acute arthritis NA BeFree Detail
<0.001 Childhood asthma NA BeFree Detail
<0.001 Coronary arteritis NA BeFree Detail
<0.001 Chronic heart failure NA BeFree Detail
<0.001 Miller Dieker syndrome NA BeFree Detail
0.012 Chronic Periodontitis NA BeFree,GAD,LHGDN Detail
0.005 idiopathic generalized epilepsy NA GAD Detail
<0.001 Impaired glucose tolerance The percentage of CD14(+)CD16(+) monocytes among all CD14(+) monocytes was signi... BeFree 25134759 Detail
<0.001 Coinfection NA BeFree Detail
<0.001 Respiratory syncytial virus bronchiolitis The role of TLR4 and CD14 polymorphisms in the pathogenesis of respiratory syncy... BeFree 25572736 Detail
<0.001 Squamous cell carcinoma of esophagus IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are assoc... BeFree 25238263 Detail
<0.001 Very Low Birth Weight NA BeFree Detail
<0.001 Infant, Very Low Birth Weight NA BeFree Detail
0.003 Restenosis NA BeFree,GAD Detail
<0.001 Tumor necrosis NA BeFree Detail
0.002 Atrophic NA GAD Detail
<0.001 malignant fibrous histiocytoma NA BeFree Detail
<0.001 histiocytic sarcoma NA BeFree Detail
<0.001 Impaired cognition NA BeFree Detail
<0.001 Stable angina The frequency of circulating CD14(+)HLA-DR(-/low) MDSCs; arginase-1 (Arg-1) expr... BeFree 25591771 Detail
<0.001 Anterior myocardial infarction NA BeFree Detail
<0.001 Asymptomatic human immunodeficiency virus infection NA BeFree Detail
<0.001 Malignant neoplasm of pancreas NA BeFree Detail
<0.001 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
0.003 Malignant neoplasm of prostate NA BeFree,GAD Detail
0.080 Endotoxemia NA RGD Detail
0.005 Pancreatitis, Alcoholic NA BeFree,GAD,LHGDN Detail
<0.001 Hereditary hemochromatosis NA BeFree Detail
0.019 Atopy NA GAD Detail
0.120 Non-alcoholic Fatty Liver Disease NA CTD_human Detail
<0.001 lupus erythematosus NA BeFree Detail
<0.001 pricking of skin NA BeFree Detail
0.002 Dermatitis and eczema NA GAD Detail
<0.001 Overweight NA BeFree Detail
0.080 Necrotizing Enterocolitis NA RGD Detail
<0.001 Metabolic syndrome X NA BeFree Detail
0.006 Hepatitis B, Chronic NA BeFree,LHGDN Detail
0.008 Hepatitis C, Chronic NA BeFree,GAD,LHGDN Detail
0.002 Malignant neoplasm of esophagus NA GAD Detail
0.002 Allergy to peanuts NA GAD Detail
0.003 Carotid Atherosclerosis NA BeFree,GAD Detail
<0.001 acute asthma NA BeFree Detail
0.006 acute pancreatitis -651C/T promoter polymorphism in the CD14 gene is associated with severity of ac... BeFree 19997857 Detail
<0.001 Carcinogenesis NA BeFree Detail
<0.001 monocytic leukemia Remarkably, LPS downregulated HO-1 in primary human peripheral blood mononuclear... BeFree 25463280 Detail
<0.001 prostate carcinoma NA BeFree Detail
0.002 hepatopulmonary syndrome NA GAD Detail
<0.001 breast carcinoma NA BeFree Detail
<0.001 bacterial sepsis NA BeFree Detail
<0.001 Malignant neoplasm of gastrointestinal tract NA BeFree Detail
<0.001 heavy drinking NA BeFree Detail
0.003 stomach carcinoma Association of CD14/-260 polymorphism with gastric cancer risk in Highland Tibet... BeFree 24627605 Detail
<0.001 Carcinoma of bladder CD14-expressing cancer cells establish the inflammatory and proliferative tumor ... BeFree 25825750 Detail
<0.001 Subfertility NA BeFree Detail
<0.001 Corneal infection NA BeFree Detail
<0.001 5q-syndrome NA BeFree Detail
<0.001 Middle Cerebral Artery Occlusion NA BeFree Detail
<0.001 Multiple Sclerosis, Relapsing-Remitting NA BeFree Detail
<0.001 Chromosome 8, monosomy 8p NA BeFree Detail
<0.001 Bacterial diarrhoea NA BeFree Detail
<0.001 Dry cough NA BeFree Detail
0.001 Helicobacter pylori infection NA BeFree Detail
<0.001 Acute GVH disease NA BeFree Detail
<0.001 Distal colitis NA BeFree Detail
<0.001 latent infection NA BeFree Detail
<0.001 Infectious disease of lung NA BeFree Detail
0.005 Chlamydophila Infections NA GAD Detail
<0.001 eczema herpeticum NA BeFree Detail
0.003 Ischemic stroke NA BeFree,GAD Detail
0.008 Acute coronary syndrome NA BeFree,GAD,LHGDN Detail
0.003 Spondylarthropathies NA BeFree,GAD Detail
<0.001 Arthritis, Collagen-Induced NA BeFree Detail
0.003 Chlamydia pneumoniae infection NA BeFree,GAD Detail
<0.001 Cholestasis in newborn NA BeFree Detail
<0.001 Invasive Ductal Breast Carcinoma NA BeFree Detail
0.003 severe acute respiratory syndrome NA BeFree,GAD Detail
<0.001 sarcoma NA BeFree Detail
<0.001 Advanced cirrhosis NA BeFree Detail
<0.001 TNF receptor-associated periodic fever syndrome (TRAPS) NA BeFree Detail
<0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
<0.001 Myelodysplastic Syndrome with Isolated del(5q) NA BeFree Detail
<0.001 M5b Acute differentiated monocytic leukemia Remarkably, LPS downregulated HO-1 in primary human peripheral blood mononuclear... BeFree 25463280 Detail
0.003 colorectal cancer GM-CSF or M-CSF-stimulated peripheral blood CD14(+) cells from healthy donors we... BeFree,GAD 24737547 Detail
<0.001 Non-Malignant Ascites Adverse Event NA BeFree Detail
<0.001 Non-ST elevation (NSTEMI) myocardial infarction NA BeFree Detail
<0.001 Immune Reconstitution Inflammatory Syndrome Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor ... BeFree 25275318 Detail
0.003 Cirrhosis NA BeFree,GAD Detail
<0.001 Peripheral Arterial Diseases NA BeFree Detail
<0.001 Refractory cytopenia with multilineage dysplasia (RCMD) NA BeFree Detail
0.001 Severe Sepsis NA BeFree Detail
<0.001 Chromosome 5, trisomy 5q NA BeFree Detail
<0.001 IMMUNE SUPPRESSION NA BeFree Detail
0.002 Venous thromboembolism NA GAD Detail
<0.001 Amyotrophic Lateral Sclerosis, Sporadic NA BeFree Detail
0.008 coronary artery disease The number of circulating CD14(+)CD16(+) monocytes is increased in patients with... BeFree,GAD,LHGDN 25134759 Detail
<0.001 Acute lyme disease NA BeFree Detail
<0.001 liver carcinoma NA BeFree Detail
0.001 Allergic rhinitis (disorder) NA BeFree Detail
<0.001 Infectious Otitis Media NA BeFree Detail
0.002 Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified NA GAD Detail
<0.001 Acute malaria NA BeFree Detail
0.080 Cerebral Hemorrhage NA RGD Detail
0.002 Pulmonary function (finding) NA GAD Detail
<0.001 Nonalcoholic Steatohepatitis NA BeFree Detail
0.123 Juvenile arthritis NA BeFree,CTD_human,GAD Detail
0.005 Allergic disposition The -159 C/T variation in the CD14 gene plays an important role in regulating CD... BeFree 25966203 Detail
<0.001 Allergic sensitization NA BeFree Detail
<0.001 Symptomatic carotid artery stenosis We analyzed 118 carotid plaques from patients with symptomatic carotid artery st... BeFree 25046588 Detail
0.018 Infection NA GAD,LHGDN Detail
<0.001 juvenile rheumatoid arthritis NA BeFree Detail
0.006 acute pancreatitis NA BeFree,GAD Detail
<0.001 adenoma NA BeFree Detail
0.003 Airway Obstruction NA LHGDN Detail
0.002 Alcoholic Intoxication, Chronic NA GAD Detail
0.002 Alveolar Bone Loss NA GAD Detail
0.005 Alzheimer's disease NA GAD Detail
<0.001 amyotrophic lateral sclerosis NA BeFree Detail
0.002 Angina Pectoris NA GAD Detail
0.006 Angina, Unstable NA BeFree,GAD,LHGDN Detail
<0.001 Anxiety Disorders In infants with the TC + CC genotype of CD14, high levels of perinatal anxiety w... BeFree 25263840 Detail
0.004 arteriosclerosis CD14 is a predictor of inflammation and associated with atherosclerosis. BeFree 25046588 Detail
0.003 arthritis NA BeFree,GAD Detail
0.011 rheumatoid arthritis The circadian rhythm in expression of the clock genes PER2 and PER3 in CD14+ mon... BeFree,GAD,LHGDN 25535886 Detail
0.011 rheumatoid arthritis Specific overexpression of tumour necrosis factor-α-induced protein (TNFAIP)9 in... BeFree,GAD,LHGDN 25683200 Detail
0.215 asthma This review aims to summarize the available evidence for, and potential effects ... BeFree,CTD_human,GAD,LHGDN 24889096 Detail
0.215 asthma Association between polymorphisms in ADAM33, CD14, and TLR4 with asthma in the U... BeFree,CTD_human,GAD,LHGDN 25036518 Detail
0.215 asthma IL13, CD14 and ADRB2, which are located in this risk locus, are among the genes ... BeFree,CTD_human,GAD,LHGDN 25233048 Detail
0.021 atherosclerosis CD14 is a predictor of inflammation and associated with atherosclerosis. BeFree,GAD,LHGDN 25046588 Detail
<0.001 Autoimmune Diseases NA BeFree Detail
0.002 Bacterial Infections These findings suggest that specific LBP, CD14 and BPI SNPs might be contributor... BeFree 24107515 Detail
0.002 Bacterial Infections Porphyromonas gingivalis gingipains selectively reduce CD14 expression, leading ... BeFree 25228314 Detail
<0.001 Behcet Syndrome Using canonical pathway enrichment analysis, JAK/STAT signaling was identified a... BeFree 25410656 Detail
0.006 biliary atresia NA BeFree,GAD,LHGDN Detail
0.003 Malignant neoplasm of urinary bladder CD14-expressing cancer cells establish the inflammatory and proliferative tumor ... BeFree,GAD 25825750 Detail
<0.001 Malignant neoplasm of breast NA BeFree Detail
0.004 bronchiolitis In infants with the TC + CC genotype of CD14, high levels of perinatal anxiety w... BeFree,LHGDN 25263840 Detail
0.004 bronchiolitis For CD14 polymorphisms, a positive association was found between the C-159T and ... BeFree,LHGDN 25572736 Detail
0.002 Bronchiolitis, Viral NA GAD Detail
0.003 brucellosis NA BeFree,GAD Detail
0.003 burning mouth syndrome NA BeFree,LHGDN Detail
<0.001 Non-small cell lung carcinoma NA BeFree Detail
<0.001 renal cell carcinoma NA BeFree Detail
Annotation

Annotations

DescrptionSourceLinks
Psoriasis patients exhibit an increased risk of death by cardiovascular disease (CVD) and have eleva... DisGeNET Detail
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GM-CSF or M-CSF-stimulated peripheral blood CD14(+) cells from healthy donors were cocultured with c... DisGeNET Detail
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Moreover, we observed that the level of miR-155 expression was up-regulated in CD14(+) monocytes fro... DisGeNET Detail
The number of circulating CD14(+)CD16(+) monocytes is increased in patients with chronic renal failu... DisGeNET Detail
Moreover, we observed that the level of miR-155 expression was up-regulated in CD14(+) monocytes fro... DisGeNET Detail
The number of circulating CD14(+)CD16(+) monocytes is increased in patients with chronic renal failu... DisGeNET Detail
Although CD14 macrophages augment intestinal inflammation in patients with CD, macrophages also prom... DisGeNET Detail
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Bezafibrate, a peroxisome proliferator-activated receptor α agonist, decreases circulating CD14(+)CD... DisGeNET Detail
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Furthermore, the aberrant expansion of the (CD14(+)CD16(+)) subset could explain the enhanced apopto... DisGeNET Detail
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We demonstrate for the first time that augmented miR-150 expression with depressed SOCS1 expression ... DisGeNET Detail
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Maintenance of virologic efficacy and decrease in levels of β2-microglobulin, soluble CD40L and solu... DisGeNET Detail
Using our previously determined optimal cut-point of 45 copies/10 cells for this cohort, a threshold... DisGeNET Detail
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The number of circulating CD14(+)CD16(+) monocytes is increased in patients with chronic renal failu... DisGeNET Detail
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In chronic lymphocytic leukemia patients, nurse-like cells differentiate from CD14(+) mononuclear ce... DisGeNET Detail
CCAAT/enhancer-binding protein (C/EBP) β, which can bind to CD14 promoter and increase its transcrip... DisGeNET Detail
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Here, we report increased expression of TLR2 in CD4(+) and CD8(+) T cells, CD19(+) B cells, and CD14... DisGeNET Detail
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The percent of CD14(+) HLA-DR(low/-) monocytes was significantly higher in the lymphoma patients tha... DisGeNET Detail
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Association of CD14/-260 polymorphism with gastric cancer risk in Highland Tibetans. DisGeNET Detail
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We found that LIGHT was overproduced by CD14+ monocytes, CD8+ T-cells and neutrophils of peripheral ... DisGeNET Detail
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This elevation could represent evidence of monocyte dysfunction in psoriasis patients at risk for CV... DisGeNET Detail
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Increased monocytic CD14⁺HLADRlow/- myeloid-derived suppressor cells in obesity. DisGeNET Detail
This massive B-cell-restricted initiation of the immune response in the early disease process of ON ... DisGeNET Detail
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Polymorphism of the CD14 and TLR4 genes and post-treatment apical periodontitis. DisGeNET Detail
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Further studies are needed to determine if reduced CD14 expression is linked to periodontitis induce... DisGeNET Detail
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In infants with the TC + CC genotype of CD14, high levels of perinatal anxiety were associated with ... DisGeNET Detail
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The association of polymorphisms of TLR4 and CD14 genes with susceptibility to sepsis in a Chinese p... DisGeNET Detail
The complement system and the Toll-like (TLR) co-receptor CD14 play important roles in innate immuni... DisGeNET Detail
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The association between C-159T polymorphism in CD14 gene and susceptibility to tuberculosis: a meta-... DisGeNET Detail
Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-asso... DisGeNET Detail
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CD14(+) HLA-DR low/(-) monocytes as indicator of disease aggressiveness in B-cell non-Hodgkin lympho... DisGeNET Detail
The percent of CD14(+) HLA-DR(low/-) monocytes was significantly higher in the lymphoma patients tha... DisGeNET Detail
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Blocking experiments with specific neutralizing antibodies for TLR1, TLR6, and CD14 showed that TLR6... DisGeNET Detail
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Association of TLR2, TLR3, TLR4 and CD14 genes polymorphisms with oral cancer risk and survival. DisGeNET Detail
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Association of CD14 C159T polymorphism with atopic asthma susceptibility in children from Southeaste... DisGeNET Detail
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Association of TLR2, TLR3, TLR4 and CD14 genes polymorphisms with oral cancer risk and survival. DisGeNET Detail
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HIV DNA in CD14+ reservoirs is associated with regional brain atrophy in patients naive to combinati... DisGeNET Detail
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The association of polymorphisms of TLR4 and CD14 genes with susceptibility to sepsis in a Chinese p... DisGeNET Detail
The complement system and the Toll-like (TLR) co-receptor CD14 play important roles in innate immuni... DisGeNET Detail
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The percentage of CD14(+)CD16(+) monocytes among all CD14(+) monocytes was significantly higher in s... DisGeNET Detail
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The role of TLR4 and CD14 polymorphisms in the pathogenesis of respiratory syncytial virus bronchiol... DisGeNET Detail
IL-6-stimulated CD11b+ CD14+ HLA-DR- myeloid-derived suppressor cells, are associated with progressi... DisGeNET Detail
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The frequency of circulating CD14(+)HLA-DR(-/low) MDSCs; arginase-1 (Arg-1) expression; and plasma l... DisGeNET Detail
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-651C/T promoter polymorphism in the CD14 gene is associated with severity of acute pancreatitis in ... DisGeNET Detail
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Remarkably, LPS downregulated HO-1 in primary human peripheral blood mononuclear cells (PBMCs), CD14... DisGeNET Detail
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Association of CD14/-260 polymorphism with gastric cancer risk in Highland Tibetans. DisGeNET Detail
CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in ... DisGeNET Detail
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Remarkably, LPS downregulated HO-1 in primary human peripheral blood mononuclear cells (PBMCs), CD14... DisGeNET Detail
GM-CSF or M-CSF-stimulated peripheral blood CD14(+) cells from healthy donors were cocultured with c... DisGeNET Detail
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Mycobacterial antigen driven activation of CD14++CD16- monocytes is a predictor of tuberculosis-asso... DisGeNET Detail
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The number of circulating CD14(+)CD16(+) monocytes is increased in patients with chronic renal failu... DisGeNET Detail
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The -159 C/T variation in the CD14 gene plays an important role in regulating CD14 expression and ha... DisGeNET Detail
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We analyzed 118 carotid plaques from patients with symptomatic carotid artery stenosis for expressio... DisGeNET Detail
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In infants with the TC + CC genotype of CD14, high levels of perinatal anxiety were associated with ... DisGeNET Detail
CD14 is a predictor of inflammation and associated with atherosclerosis. DisGeNET Detail
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The circadian rhythm in expression of the clock genes PER2 and PER3 in CD14+ monocytes was lost in p... DisGeNET Detail
Specific overexpression of tumour necrosis factor-α-induced protein (TNFAIP)9 in CD14(+) CD16(-) mon... DisGeNET Detail
This review aims to summarize the available evidence for, and potential effects of, an interaction b... DisGeNET Detail
Association between polymorphisms in ADAM33, CD14, and TLR4 with asthma in the Uygur population in C... DisGeNET Detail
IL13, CD14 and ADRB2, which are located in this risk locus, are among the genes most strongly associ... DisGeNET Detail
CD14 is a predictor of inflammation and associated with atherosclerosis. DisGeNET Detail
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These findings suggest that specific LBP, CD14 and BPI SNPs might be contributory assessments in stu... DisGeNET Detail
Porphyromonas gingivalis gingipains selectively reduce CD14 expression, leading to macrophage hypore... DisGeNET Detail
Using canonical pathway enrichment analysis, JAK/STAT signaling was identified as activated in both ... DisGeNET Detail
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CD14-expressing cancer cells establish the inflammatory and proliferative tumor microenvironment in ... DisGeNET Detail
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In infants with the TC + CC genotype of CD14, high levels of perinatal anxiety were associated with ... DisGeNET Detail
For CD14 polymorphisms, a positive association was found between the C-159T and the development of b... DisGeNET Detail
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Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386599687 dbSNP
Genome
hg38
Position
chr5:140,631,728-140,633,700
Variant Type
snv
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