Gram-Negative Bacterial Infections

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Information
Disease name
Gram-Negative Bacterial Infections
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT00079989 Completed Phase 3 Study Evaluating Tigecycline in Selected Serious Infections Due to Resistant Gram-Negative Organisms December 2003 November 2005
NCT00177814 Completed Piperacillin as a Part of Antibiotic Streamlining in the Intensive Care Unit September 2005 June 2017
NCT00177957 Completed Gram Negative Bacteremia, Risk Factors for Failure of Therapy April 2005 May 2016
NCT00406198 Completed Phase 4 Impact of Continuous Venovenous Haemofiltration on Organ Failure During the Early Phase of Severe Sepsis March 1997 December 1999
NCT00490477 Completed Phase 3 The Effects of Polymyxin-B Protects on Sepsis Induced Kidney Dysfunction: a Randomized Clinical Trial May 2006 December 2007
NCT00629382 Completed Phase 4 Early Use of Polymyxin B Hemoperfusion in Abdominal Sepsis December 2004 April 2008
NCT00723502 Completed Phase 2 Efficacy and Safety Study of Finafloxacin Used in Helicobacter Pylori Infected Patients September 2008 April 2009
NCT00874367 Completed Early-Onset Sepsis Surveillance Study February 2006 May 2011
NCT01732250 Completed Phase 4 Multicenter Open-label Randomized Controlled Trial (RCT) to Compare Colistin Alone Versus Colistin Plus Meropenem March 2013 February 28, 2017
NCT02088840 Completed Survey of Severe Infections by Gram Negative Bacteria in Patients Submitted to Stem Cell Transplant January 2014 April 2016
NCT02285075 Completed Phase 4 Temocillin Pharmacokinetic in Hemodialysis June 2011 December 2014
NCT02962934 Completed An Observational Pharmacokinetic Sudy of Ceftolozane-Tazobactam in Intensive Care Unit in Patients With and Without CRRT November 30, 2016 August 2019
NCT03160040 Completed A Retrospective Observational Study to Evaluate the Utilization, Outcomes, and Adverse Events in Participants Treated With Minocin® (Minocycline) for Infections Caused by Gram-negative Bacteria in a Real World Setting October 11, 2017 May 1, 2018
NCT03182504 Completed Phase 1 A Study to Investigate the Intrapulmonary Lung Penetration of Nacubactam in Healthy Participants June 15, 2017 August 10, 2017
NCT03397914 Completed Phase 4 Effect of Different Colistin Doses on Clinical Outcome of Pediatric Cancer Patients With Gram Negative Infections January 2017 March 2019
NCT04335539 Completed Phase 2 A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of Cefiderocol in Hospitalized Pediatric Participants August 21, 2020 February 6, 2023
NCT06135350 Not yet recruiting Phase 2 Clinical Trial to Study the Efficacy and Safety of Fluorothiazinone (N.F. Gamaleya NRCEM) in Prophylaxis of Nosocomial Bacterial Infections With Participation of Patients on MV November 2023 December 2024
NCT04215991 Recruiting Phase 2 A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Pediatric Participants February 19, 2020 September 30, 2024
NCT04861922 Recruiting Phase 3 Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal Infection May 11, 2021 July 30, 2024
NCT05639647 Recruiting Phase 2 Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections April 18, 2023 February 18, 2026
NCT06086626 Recruiting Phase 2 A Study to Assess the Safety, Tolerability, and Pharmacokinetics of Cefiderocol in Hospitalized Neonates and Infants March 14, 2024 December 31, 2024
NCT00563134 Suspended N/A A Randomised Trial on the Saftely and Efficacy of GR270774 in the Treatment of Gram-negative Sepsis in Adult October 2005 December 2006
NCT05210387 Terminated N/A Seven Versus 14 Days of Antibiotic Therapy for Multidrug-resistant Gram-negative Bacilli Infections January 27, 2022 December 31, 2023
NCT02666274 Unknown status Feasibility Studies to Inform Novel Proposals to Avert Community-Based Antimicrobial Resistance Spread December 2015 June 2017
NCT05171257 Unknown status Quantifying Gram-negative Resistance to Empiric Therapy in the Intensive Care Unit October 19, 2021 December 30, 2022
NCT01600768 Unknown status N/A Evaluation of Extended Intravenous of Beta-lactams in the Treatment of Serious Gram-negative Infections in Critically Ill Patients February 2012 December 2015
NCT04055922 Unknown status Comparison of Solid Organ Transplant May 3, 2018 May 2021
NCT04917380 Unknown status The Clinical Character,Risk and Prognosis of Post-neurosurgical Intracranial Infection With Different Pathogens. June 10, 2021 October 30, 2021
NCT00394784 Withdrawn Surveillance Study - Incidence of Antibiotic Resistance in Serial Gram-negative Bloodstream Isolates December 2006 December 2025
NCT04785924 Withdrawn Phase 4 Imipenem/Cilastatin/Relebactam (IMI/REL) in Treatment of CRE Infections June 7, 2021 January 12, 2023
MeSH unique ID (MeSH (Medical Subject Headings))
D016905