Annotation Detail
Information
- Associated Genes
- CD14
- Associated Variants
-
CD14 MUTATION
CD14 MUTATION - Associated Disease
- Crohn Disease
- Source Database
- DisGeNET
- Description
- Although CD14 macrophages augment intestinal inflammation in patients with CD, macrophages also promote a negative feedback pathway through the activation of IL-22 production by RORγt ILCs.
- Pubmed
- 24991784
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 15
- Original source reporting the Gene Disease association
- BeFree,GAD,LHGDN
- DisGENET score for the Gene Disease association
- 0.0310950582456375
Drugs