Annotation Detail
Information
- Associated Genes
- CD14
- Associated Variants
-
CD14 MUTATION
CD14 MUTATION - Associated Disease
- monocytic leukemia
- Source Database
- DisGeNET
- Description
- Remarkably, LPS downregulated HO-1 in primary human peripheral blood mononuclear cells (PBMCs), CD14(+) monocytes, macrophages, dendritic cells, and granulocytes, but upregulated this enzyme in primary murine macrophages and human monocytic leukemia cell lines.
- Pubmed
- 25463280
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 5
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs