chr15:74719542:> Detail (hg38)

Information

Genome

Assembly Position
hg19 chr15:75,011,883-75,017,877 
hg38 chr15:74,719,542-74,725,536

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
0.076 squamous cell carcinoma NA BeFree,GAD,LHGDN Detail
0.003 Cardiovascular Diseases NA BeFree,GAD Detail
0.002 Neoplastic Cell Transformation NA GAD Detail
0.003 cerebral infarction NA BeFree,GAD Detail
0.014 Uterine Cervical Neoplasm NA BeFree,GAD Detail
<0.001 cholelithiasis NA BeFree Detail
0.002 intrahepatic cholestasis NA GAD Detail
0.005 chorioamnionitis NA GAD,LHGDN Detail
0.014 Chromosome Aberrations NA GAD Detail
0.001 Congenital chromosomal disease NA BeFree Detail
0.007 cleft lip NA GAD Detail
0.007 cleft palate NA GAD Detail
0.007 Cocarcinogenesis NA GAD Detail
<0.001 colitis NA BeFree Detail
0.002 ulcerative colitis NA GAD Detail
0.008 Colonic Neoplasms NA BeFree,GAD,LHGDN Detail
0.002 Colonic Polyps NA GAD Detail
0.023 Colorectal Neoplasms NA BeFree,GAD,LHGDN Detail
0.003 Hereditary nonpolyposis colorectal neoplasms NA LHGDN Detail
0.002 Connective Tissue Diseases NA GAD Detail
0.002 Coronary Arteriosclerosis The association between CYP1A1 genetic polymorphisms and coronary artery disease... BeFree 25189712 Detail
0.002 Coronary heart disease The association between CYP1A1 genetic polymorphisms and coronary artery disease... BeFree 25189712 Detail
0.003 Crohn Disease NA BeFree,GAD Detail
0.002 cystadenocarcinoma NA GAD Detail
0.120 Drug Eruptions NA CTD_human Detail
<0.001 Dermatitis, Atopic NA BeFree Detail
0.120 contact dermatitis NA CTD_human Detail
<0.001 Diabetes NA BeFree Detail
<0.001 diabetes mellitus NA BeFree Detail
0.200 Diabetes Mellitus, Experimental NA CTD_human,RGD Detail
0.005 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree,GAD Detail
0.024 DNA Damage NA GAD Detail
0.018 Dysmenorrhea NA GAD,LHGDN Detail
0.005 echinococcosis NA GAD,LHGDN Detail
0.002 Pathological accumulation of air in tissues NA GAD Detail
0.019 Endometrial Neoplasms NA GAD,LHGDN Detail
0.003 endometrial hyperplasia NA BeFree,GAD Detail
0.027 endometriosis NA BeFree,GAD,LHGDN Detail
0.002 Disorder of eye NA GAD Detail
0.002 Fetal Diseases NA GAD Detail
0.007 Fetal Growth Retardation NA GAD Detail
<0.001 breast fibrocystic disease NA BeFree Detail
0.003 Fibrosis NA LHGDN Detail
0.005 gallbladder neoplasm NA LHGDN Detail
0.002 Female Genital Diseases NA GAD Detail
<0.001 Glioma NA BeFree Detail
0.005 Graves Disease NA BeFree,GAD Detail
0.120 Hamartoma NA BeFree,CTD_human Detail
0.036 Head and Neck Neoplasms NA GAD,LHGDN Detail
0.080 Heart Diseases NA RGD Detail
0.120 Cardiomegaly NA CTD_human Detail
<0.001 Hemorrhoids NA BeFree Detail
0.002 hepatitis B NA GAD Detail
0.003 hepatitis C NA BeFree,LHGDN Detail
0.002 HIV Infections NA GAD Detail
0.007 Hodgkin Disease NA GAD Detail
<0.001 hydronephrosis NA BeFree Detail
0.002 Hypercholesterolemia NA GAD Detail
0.122 Hypersensitivity NA CTD_human,GAD Detail
0.124 Hypertensive disease Logistic regression was performed to investigate the association of smoking and ... BeFree,CTD_human,GAD 25902778 Detail
0.002 Hypopharyngeal Neoplasms NA GAD Detail
0.085 Inflammation NA GAD,RGD Detail
0.080 Kidney Failure, Chronic NA RGD Detail
0.122 Kidney Neoplasm NA CTD_human,GAD Detail
0.019 Laryngeal neoplasm NA GAD Detail
0.008 Fibroid Tumor NA BeFree,GAD,LHGDN Detail
0.021 leukemia NA BeFree,GAD,LHGDN Detail
0.007 chronic lymphocytic leukemia NA BeFree,GAD Detail
0.004 Acute lymphocytic leukemia NA BeFree Detail
0.006 Leukemia, Lymphocytic, Acute, L1 NA BeFree,GAD Detail
0.007 Leukemia, Myelocytic, Acute NA BeFree,GAD,LHGDN Detail
0.009 myeloid leukemia NA GAD Detail
0.003 Myeloid Leukemia, Chronic NA BeFree,GAD Detail
<0.001 leukopenia NA BeFree Detail
0.003 Leukoplakia NA BeFree,GAD Detail
0.005 Leukoplakia, Oral NA BeFree,GAD Detail
<0.001 liver cirrhosis For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... BeFree 25024626 Detail
0.005 Liver Cirrhosis, Alcoholic For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... BeFree,GAD 25024626 Detail
0.008 Liver diseases NA BeFree,GAD Detail
0.008 Liver neoplasms NA BeFree,GAD Detail
0.080 Liver Neoplasms, Experimental NA RGD Detail
<0.001 Lung diseases Our novel results on estradiol metabolism in fetal and early postnatal lung in t... BeFree 25399436 Detail
0.133 Chronic Obstructive Airway Disease NA BeFree,CTD_human,GAD,LHGDN Detail
0.051 Lung Neoplasms NA BeFree,GAD,LHGDN Detail
0.011 Lupus Erythematosus, Systemic NA BeFree,GAD,LHGDN Detail
0.005 lymphoma NA BeFree,GAD Detail
0.002 Lymphoma, Follicular NA GAD Detail
0.019 Lymphoma, Non-Hodgkin NA BeFree,GAD Detail
0.015 Malignant neoplasm of stomach However, available data collected by the study failed to reveal remarkable assoc... BeFree,GAD 24969905 Detail
0.002 Animal Mammary Neoplasms NA GAD Detail
0.003 melanoma NA BeFree,GAD Detail
0.002 Mesothelioma NA GAD Detail
0.040 Mouth Neoplasms NA GAD Detail
0.003 multiple myeloma NA BeFree,GAD Detail
0.002 Musculoskeletal Diseases NA GAD Detail
<0.001 myocardial infarction NA BeFree Detail
0.080 Nematode infections NA RGD Detail
0.002 Neoplasm Invasiveness NA GAD Detail
<0.001 Neoplasm Metastasis NA BeFree Detail
0.002 Neoplasms, Germ Cell and Embryonal NA GAD Detail
0.002 Neoplasms, Multiple Primary NA GAD Detail
<0.001 obesity NA BeFree Detail
0.122 Occupational Diseases NA CTD_human,GAD Detail
<0.001 oral submucous fibrosis NA BeFree Detail
0.002 Oropharyngeal Neoplasms NA GAD Detail
0.003 osteoporosis NA BeFree,LHGDN Detail
0.002 Osteoporosis, Postmenopausal NA GAD Detail
0.003 ovarian carcinoma Increased expression of CYP1 family indicates the possibility of carcinogenesis ... BeFree 25448748 Detail
0.001 Ovarian Diseases NA BeFree Detail
0.002 Pancreatic Neoplasm NA GAD Detail
0.003 pancreatitis NA LHGDN Detail
0.002 Parkinson disease NA GAD Detail
<0.001 Peptic Ulcer NA BeFree Detail
0.005 periodontitis NA BeFree,GAD,LHGDN Detail
0.002 Peripheral neuropathy NA GAD Detail
0.012 Pharyngeal Neoplasms NA GAD,LHGDN Detail
0.002 Pleural Neoplasms NA GAD Detail
0.003 pneumonia NA BeFree,GAD Detail
0.011 polycystic ovary syndrome NA BeFree,GAD,LHGDN Detail
<0.001 polycythemia vera NA BeFree Detail
0.005 pre-eclampsia NA GAD Detail
0.005 Precancerous Conditions NA BeFree,GAD Detail
0.007 Pregnancy Complications NA GAD Detail
0.002 Pregnancy Complications, Hematologic NA GAD Detail
0.005 Preleukemia NA GAD Detail
0.007 Prenatal Exposure Delayed Effects NA GAD Detail
0.137 Prostatic Neoplasms NA BeFree,CTD_human,LHGDN Detail
0.005 psoriasis NA GAD,LHGDN Detail
0.003 pterygium NA BeFree,GAD Detail
<0.001 Precocious Puberty Are CYP1A1, CYP17 and CYP1B1 mutation genes involved on girls with precocious pu... BeFree 25150952 Detail
0.080 Reperfusion Injury NA RGD Detail
0.005 Respiratory Tract Diseases NA GAD Detail
0.002 Rhinitis, Allergic, Perennial NA GAD Detail
<0.001 Seizures NA BeFree Detail
0.005 Dermatologic disorders NA GAD Detail
<0.001 Skin Manifestations NA BeFree Detail
0.002 Skin Neoplasms NA GAD Detail
0.003 ankylosing spondylitis NA BeFree,LHGDN Detail
0.017 Stomach Neoplasms NA GAD Detail
<0.001 Cerebrovascular accident NA BeFree Detail
0.003 sudden infant death syndrome NA BeFree,GAD Detail
0.005 Testicular Neoplasms NA GAD,LHGDN Detail
<0.001 Thromboembolism NA BeFree Detail
0.002 Thyroid Neoplasm NA GAD Detail
0.003 Thyroid Nodule NA BeFree,GAD Detail
0.009 Tobacco use disorder NA GAD Detail
0.002 Tuberculosis, Pulmonary NA GAD Detail
0.004 Uterine Fibroids The genetic polymorphisms of IVS1+2329C>T and Val158Met loci in COMT, Ile462Val ... BeFree,GAD 24320736 Detail
0.005 Uterine Neoplasms NA GAD Detail
<0.001 Vascular Diseases NA BeFree Detail
<0.001 Virus Diseases NA BeFree Detail
<0.001 Wheezing NA BeFree Detail
0.005 diffuse large B-cell lymphoma NA BeFree,GAD Detail
<0.001 Lymphoma, Large-Cell, Follicular NA BeFree Detail
0.003 T-Cell Lymphoma NA BeFree,GAD Detail
0.120 Peripheral Vascular Diseases NA CTD_human Detail
<0.001 Li-Fraumeni syndrome Using p53 heterozygous mutant epithelial cells from patients with Li-Fraumeni sy... BeFree 24736433 Detail
0.003 Arthritis, Reactive NA BeFree,LHGDN Detail
0.006 Non-small cell lung carcinoma In this study, CYP1A1 (Ile462Val), CYP1B1(Asn453Ser), GST M1, GSTP1 exon 5 (Ile1... BeFree 20845989 Detail
0.001 acute leukemia NA BeFree Detail
<0.001 Depressive Symptoms NA BeFree Detail
0.003 Squamous cell carcinoma of lung NA BeFree Detail
<0.001 Small cell carcinoma of lung NA BeFree Detail
0.019 Premature Birth NA GAD Detail
<0.001 Oral Cavity Carcinoma NA BeFree Detail
0.004 Uterine Fibroids The genetic polymorphism of rs3087869 (IVS1+2329C&gt;T) (OR 3.200, 95% CI 1.614-... BeFree 24777039 Detail
0.005 Adenocarcinoma of lung (disorder) NA BeFree,GAD Detail
0.007 Malignant neoplasm of mouth The results also suggested significant association between tobacco habits, espec... BeFree,GAD 23444898 Detail
0.007 Malignant neoplasm of mouth CYP1A1 polymorphism interactions with smoking status in oral cancer risk: eviden... BeFree,GAD 25106409 Detail
0.007 Malignant neoplasm of mouth Our findings suggest that presence of GSTM1 and/or GSTT1 null genotypes along wi... BeFree,GAD 25735346 Detail
0.007 Malignant neoplasm of mouth Association of CYP1A1 and GSTM1 Polymorphisms With Oral Cancer Susceptibility: A... BeFree,GAD 26166128 Detail
<0.001 Malignant neoplasm of pharynx NA BeFree Detail
0.002 Malignant neoplasm of gallbladder NA BeFree Detail
<0.001 Malignant neoplasm of testis NA BeFree Detail
0.005 Malignant neoplasm of brain NA BeFree,GAD Detail
<0.001 endometriosis of ovary NA BeFree Detail
0.002 iron deficiency anemia NA GAD Detail
0.120 Dermatitis, Allergic Contact NA CTD_human Detail
0.002 hidradenitis suppurativa NA GAD Detail
<0.001 Fibroadenoma NA BeFree Detail
0.002 Adenocarcinoma, Clear Cell NA GAD Detail
0.002 Carcinoma, Endometrioid NA GAD Detail
0.002 Cystadenocarcinoma, Serous NA GAD Detail
0.008 Cervical Intraepithelial Neoplasia NA BeFree,GAD Detail
0.002 Squamous Cell Neoplasms NA GAD Detail
<0.001 Angiofibroma NA BeFree Detail
<0.001 childhood brain tumor NA BeFree Detail
<0.001 Adult Acute Myeloblastic Leukemia NA BeFree Detail
0.005 Lip and oral cavity carcinoma The results also suggested significant association between tobacco habits, espec... BeFree 23444898 Detail
0.005 Lip and oral cavity carcinoma CYP1A1 polymorphism interactions with smoking status in oral cancer risk: eviden... BeFree 25106409 Detail
0.005 Lip and oral cavity carcinoma Our findings suggest that presence of GSTM1 and/or GSTT1 null genotypes along wi... BeFree 25735346 Detail
0.005 Lip and oral cavity carcinoma Association of CYP1A1 and GSTM1 Polymorphisms With Oral Cancer Susceptibility: A... BeFree 26166128 Detail
<0.001 Malignant neoplasm of female breast NA BeFree Detail
0.002 gallbladder carcinoma NA BeFree Detail
<0.001 pancreatic carcinoma NA BeFree Detail
0.002 Alcohol-Related Disorders NA GAD Detail
0.124 Malignant neoplasm of lung Susceptibility of lung cancer with polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1 ... BeFree,GAD 25040976 Detail
0.124 Malignant neoplasm of lung We evaluated 23 single nucleotide polymorphisms (SNPs) in the five nicotinic rec... BeFree,GAD 25233467 Detail
0.124 Malignant neoplasm of lung The aim of this study was to evaluate the contribution of CYP1A1*2A, CYP1A1*2C, ... BeFree,GAD 25388590 Detail
0.005 age related macular degeneration NA GAD Detail
0.080 Acute Lung Injury NA RGD Detail
0.200 Hyperoxia NA CTD_human,RGD Detail
0.080 Sepsis NA RGD Detail
<0.001 Carcinoma of ampulla of Vater NA BeFree Detail
<0.001 Carcinoma, Small Cell NA BeFree Detail
<0.001 Chloracne NA BeFree Detail
<0.001 Xeroderma pigmentosum, group A NA BeFree Detail
0.120 Lung Injury NA CTD_human Detail
0.017 Cancer of Head and Neck Similarly, tobacco-betel quid chewers carrying CYP1A1 TC/CC + GSTM1 null genotyp... BeFree,GAD 25724184 Detail
0.001 Squamous cell carcinoma of esophagus NA BeFree Detail
<0.001 Transitional cell carcinoma of bladder NA BeFree Detail
<0.001 Solid tumour NA BeFree Detail
<0.001 laryngeal squamous cell carcinoma NA BeFree Detail
<0.001 Adenocarcinoma of pancreas NA BeFree Detail
0.002 Focal Nodular Hyperplasia NA GAD Detail
<0.001 adenocarcinoma in situ NA BeFree Detail
<0.001 Thyroid associated opthalmopathies NA BeFree Detail
<0.001 Glaucoma, Primary Open Angle The frequency of the homozygous wild-type (w1/w1) CYP1A1 gene among patients wit... BeFree 25501250 Detail
<0.001 Chronic liver disease NA BeFree Detail
<0.001 endometriosis of uterus NA BeFree Detail
<0.001 Human papilloma virus infection NA BeFree Detail
0.007 Malignant neoplasm of liver NA GAD Detail
0.003 malignant mesothelioma NA BeFree,GAD Detail
0.007 Malignant neoplasm of pancreas NA BeFree,GAD Detail
0.075 Malignant neoplasm of prostate NA BeFree,GAD Detail
0.002 Pancreatitis, Alcoholic NA GAD Detail
0.009 endometrial carcinoma NA BeFree,GAD Detail
<0.001 Hepatitis B, Chronic NA BeFree Detail
<0.001 Environmental Carcinogenesis NA BeFree Detail
<0.001 Palmar-plantar erythrodysesthesia syndrome NA BeFree Detail
0.003 Thyroid carcinoma NA BeFree,GAD Detail
0.005 Menopause present (finding) NA GAD Detail
<0.001 Carcinoma of larynx NA BeFree Detail
0.009 Carcinogenesis Increased expression of CYP1 family indicates the possibility of carcinogenesis ... BeFree 25448748 Detail
<0.001 Chemical Carcinogenesis NA BeFree Detail
<0.001 Tumor Initiation NA BeFree Detail
0.006 prostate carcinoma NA BeFree Detail
<0.001 Epithelial ovarian cancer NA BeFree Detail
0.024 breast carcinoma 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA le... BeFree 23700305 Detail
0.024 breast carcinoma Here, we focus on recent advances in the understanding of molecular mechanisms t... BeFree 25257533 Detail
0.044 Carcinoma of lung Susceptibility of lung cancer with polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1 ... BeFree 25040976 Detail
0.044 Carcinoma of lung We evaluated 23 single nucleotide polymorphisms (SNPs) in the five nicotinic rec... BeFree 25233467 Detail
0.044 Carcinoma of lung The aim of this study was to evaluate the contribution of CYP1A1*2A, CYP1A1*2C, ... BeFree 25388590 Detail
<0.001 colon carcinoma NA BeFree Detail
0.003 stomach carcinoma However, available data collected by the study failed to reveal remarkable assoc... BeFree 24969905 Detail
0.003 Carcinoma of bladder NA BeFree Detail
0.003 skin carcinoma NA BeFree,GAD Detail
<0.001 Dissecting aneurysm of the thoracic aorta NA BeFree Detail
<0.001 bile duct carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of kidney NA BeFree Detail
<0.001 Pharyngeal Carcinoma NA BeFree Detail
<0.001 malignant pleural mesothelioma NA BeFree Detail
0.005 hypospadias NA BeFree,GAD,LHGDN Detail
0.003 Helicobacter pylori infection NA BeFree,GAD Detail
<0.001 Smoker's lung NA BeFree Detail
<0.001 Sickle Cell Dactylitis NA BeFree Detail
<0.001 Invasive breast carcinoma NA BeFree Detail
<0.001 Testicular malignant germ cell tumor NA BeFree Detail
<0.001 breast adenocarcinoma NA BeFree Detail
<0.001 Carcinogenicity In conclusion, the present work shows a strong evidence that MET inhibits the DM... BeFree 25697376 Detail
<0.001 Malignant melanoma, metastatic NA BeFree Detail
0.010 ovarian neoplasm NA BeFree,GAD Detail
0.002 Genomic Instability NA GAD Detail
0.002 Microsatellite Instability NA GAD Detail
<0.001 cholecystolithiasis NA BeFree Detail
0.003 Acute coronary syndrome NA BeFree,GAD Detail
<0.001 Polyp of large intestine NA BeFree Detail
<0.001 Nosocomial pneumonia NA BeFree Detail
0.005 Papillomavirus Infections NA GAD Detail
0.017 Malignant neoplasm of ovary Increased expression of CYP1 family indicates the possibility of carcinogenesis ... BeFree,GAD 25448748 Detail
0.005 Squamous cell carcinoma of the head and neck Meta-analyses of the effect of CYP1A1 and CYP2D6 polymorphisms on the risk of he... BeFree,GAD 25138301 Detail
0.005 Squamous cell carcinoma of the head and neck LR analysis revealed that subjects carrying CYP1A1 TC/CC + GSTM1 null genotypes ... BeFree,GAD 25724184 Detail
0.002 Systemic arterial pressure NA GAD Detail
0.002 Mesothelioma (malignant, clinical disorder) (disorder) NA GAD Detail
<0.001 Precursor B-cell lymphoblastic leukemia NA BeFree Detail
0.001 Adenoma of large intestine NA BeFree Detail
<0.001 Adenocarcinoma of large intestine NA BeFree Detail
<0.001 Cervical Squamous Intraepithelial Neoplasia NA BeFree Detail
0.001 childhood leukemia NA BeFree Detail
<0.001 gastric cardia carcinoma NA BeFree Detail
<0.001 Hereditary Nonpolyposis Colorectal Cancer NA BeFree Detail
<0.001 Infiltrating Cervical Carcinoma NA BeFree Detail
0.005 Testicular Germ Cell Tumor NA GAD Detail
<0.001 renal carcinoma NA BeFree Detail
0.120 Micronuclei, Chromosome-Defective NA CTD_human Detail
0.159 Mammary Neoplasms NA BeFree,CTD_human,GAD,LHGDN Detail
<0.001 Hepatocarcinogenesis NA BeFree Detail
<0.001 Tumor Promotion NA BeFree Detail
<0.001 Cirrhosis For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... BeFree 25024626 Detail
<0.001 Penile hypospadias NA BeFree Detail
<0.001 Benign Prostatic Hyperplasia NA BeFree Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
0.007 Mammographic Density NA BeFree,GAD Detail
<0.001 Aryl Hydrocarbon Hydroxylase Inducibility NA BeFree Detail
0.004 uterine corpus cancer NA BeFree Detail
0.017 coronary artery disease The association between CYP1A1 genetic polymorphisms and coronary artery disease... BeFree,GAD,LHGDN 25189712 Detail
0.017 coronary artery disease Moreover, it also shows the effect of smoking-gene interaction on CAD risk, wher... BeFree,GAD,LHGDN 25902778 Detail
0.030 Precursor Cell Lymphoblastic Leukemia Lymphoma NA BeFree,GAD,LHGDN Detail
0.134 liver carcinoma However, available data collected by the study failed to reveal remarkable assoc... BeFree,CTD_human,GAD 24969905 Detail
0.134 liver carcinoma For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decrea... BeFree,CTD_human,GAD 25024626 Detail
0.134 liver carcinoma Association between the CYP1A1 polymorphisms and hepatocellular carcinoma: a met... BeFree,CTD_human,GAD 25730047 Detail
0.002 caffeine stimulant related disorder NA GAD Detail
<0.001 Prostate cancer, familial NA BeFree Detail
0.005 myelodysplastic syndrome NA GAD Detail
0.002 Infection NA GAD Detail
0.001 Experimental Organism Basal Cell Carcinoma NA BeFree Detail
<0.001 Lymphoblastic leukemia in children NA BeFree Detail
0.007 colorectal carcinoma The CYP1A1-3801-CC (AOR = 0.47, 95% CI: 0.23, 0.94) and CYP2C9-430-CT (AOR = 0.8... BeFree 20937634 Detail
0.072 colorectal cancer The CYP1A1-3801-CC (AOR = 0.47, 95% CI: 0.23, 0.94) and CYP2C9-430-CT (AOR = 0.8... BeFree 20937634 Detail
0.002 Congenital Abnormality NA GAD Detail
0.122 Spontaneous abortion NA CTD_human,GAD Detail
0.002 Abortion, Habitual NA GAD Detail
0.014 adenocarcinoma NA BeFree,GAD Detail
0.008 adenoma NA BeFree,GAD,LHGDN Detail
0.005 Alcoholic Intoxication, Chronic NA GAD Detail
0.005 Alzheimer's disease NA GAD Detail
0.003 amyotrophic lateral sclerosis NA BeFree,GAD Detail
0.007 aplastic anemia NA GAD,LHGDN Detail
0.003 arteriosclerosis NA BeFree,GAD Detail
0.120 Arteritis NA CTD_human Detail
0.005 arthritis NA GAD Detail
0.005 Arthritis, Psoriatic NA BeFree,GAD,LHGDN Detail
0.010 asthma NA BeFree,GAD Detail
0.008 atherosclerosis NA BeFree,GAD Detail
0.002 autistic disorder NA GAD Detail
0.002 Barrett esophagus NA GAD Detail
<0.001 Basal Cell Nevus Syndrome NA BeFree Detail
0.005 Behcet Syndrome NA BeFree,GAD,LHGDN Detail
0.030 Malignant neoplasm of urinary bladder NA BeFree,GAD Detail
0.003 Bladder Neoplasm NA BeFree,LHGDN Detail
0.002 Blood Coagulation Disorders NA GAD Detail
<0.001 borderline personality disorder NA BeFree Detail
<0.001 Brain Neoplasms NA BeFree Detail
0.104 Malignant neoplasm of breast 2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA le... BeFree,GAD 23700305 Detail
0.104 Malignant neoplasm of breast Here, we focus on recent advances in the understanding of molecular mechanisms t... BeFree,GAD 25257533 Detail
0.002 bronchitis NA GAD Detail
<0.001 bronchopulmonary dysplasia NA BeFree Detail
<0.001 Malignant tumor of colon NA BeFree Detail
0.004 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 female breast carcinoma NA BeFree Detail
0.003 Malignant neoplasm of larynx NA BeFree,GAD Detail
<0.001 Rectal Carcinoma NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
0.002 basal cell carcinoma NA GAD Detail
<0.001 Bronchogenic Carcinoma NA BeFree Detail
0.005 mucinous adenocarcinoma NA GAD Detail
0.006 Non-small cell lung carcinoma NA BeFree,GAD Detail
0.003 Carcinoma, Papillary NA BeFree,GAD Detail
0.084 renal cell carcinoma Association between cytochrome P450 1A1 (CYP1A1) gene polymorphisms and the risk... BeFree,GAD,RGD 25630554 Detail
Annotation

Annotations

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Logistic regression was performed to investigate the association of smoking and selected susceptibil... DisGeNET Detail
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For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... DisGeNET Detail
For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... DisGeNET Detail
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Our novel results on estradiol metabolism in fetal and early postnatal lung in the context of hypero... DisGeNET Detail
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However, available data collected by the study failed to reveal remarkable associations of GC or HC ... DisGeNET Detail
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Increased expression of CYP1 family indicates the possibility of carcinogenesis by exposure of xenob... DisGeNET Detail
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Are CYP1A1, CYP17 and CYP1B1 mutation genes involved on girls with precocious puberty? A pilot study... DisGeNET Detail
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The genetic polymorphisms of IVS1+2329C>T and Val158Met loci in COMT, Ile462Val and Gly45Asp loci in... DisGeNET Detail
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Using p53 heterozygous mutant epithelial cells from patients with Li-Fraumeni syndrome, we show that... DisGeNET Detail
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In this study, CYP1A1 (Ile462Val), CYP1B1(Asn453Ser), GST M1, GSTP1 exon 5 (Ile105Val) and exon 6(Al... DisGeNET Detail
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The genetic polymorphism of rs3087869 (IVS1+2329C&gt;T) (OR 3.200, 95% CI 1.614-6.345) and rs4680 (V... DisGeNET Detail
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The results also suggested significant association between tobacco habits, especially chewing, varia... DisGeNET Detail
CYP1A1 polymorphism interactions with smoking status in oral cancer risk: evidence from epidemiologi... DisGeNET Detail
Our findings suggest that presence of GSTM1 and/or GSTT1 null genotypes along with variant alleles o... DisGeNET Detail
Association of CYP1A1 and GSTM1 Polymorphisms With Oral Cancer Susceptibility: A Meta-Analysis. DisGeNET Detail
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The results also suggested significant association between tobacco habits, especially chewing, varia... DisGeNET Detail
CYP1A1 polymorphism interactions with smoking status in oral cancer risk: evidence from epidemiologi... DisGeNET Detail
Our findings suggest that presence of GSTM1 and/or GSTT1 null genotypes along with variant alleles o... DisGeNET Detail
Association of CYP1A1 and GSTM1 Polymorphisms With Oral Cancer Susceptibility: A Meta-Analysis. DisGeNET Detail
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Susceptibility of lung cancer with polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 genotypes ... DisGeNET Detail
We evaluated 23 single nucleotide polymorphisms (SNPs) in the five nicotinic receptor related genes ... DisGeNET Detail
The aim of this study was to evaluate the contribution of CYP1A1*2A, CYP1A1*2C, CYP2D6*4, GSTP1, GST... DisGeNET Detail
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Similarly, tobacco-betel quid chewers carrying CYP1A1 TC/CC + GSTM1 null genotypes also had several ... DisGeNET Detail
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The frequency of the homozygous wild-type (w1/w1) CYP1A1 gene among patients with primary open-angle... DisGeNET Detail
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Increased expression of CYP1 family indicates the possibility of carcinogenesis by exposure of xenob... DisGeNET Detail
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2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA lesions in human breas... DisGeNET Detail
Here, we focus on recent advances in the understanding of molecular mechanisms that mediate this cro... DisGeNET Detail
Susceptibility of lung cancer with polymorphisms of CYP1A1, GSTM1, GSTM3, GSTT1 and GSTP1 genotypes ... DisGeNET Detail
We evaluated 23 single nucleotide polymorphisms (SNPs) in the five nicotinic receptor related genes ... DisGeNET Detail
The aim of this study was to evaluate the contribution of CYP1A1*2A, CYP1A1*2C, CYP2D6*4, GSTP1, GST... DisGeNET Detail
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However, available data collected by the study failed to reveal remarkable associations of GC or HC ... DisGeNET Detail
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In conclusion, the present work shows a strong evidence that MET inhibits the DMBA-mediated carcinog... DisGeNET Detail
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Increased expression of CYP1 family indicates the possibility of carcinogenesis by exposure of xenob... DisGeNET Detail
Meta-analyses of the effect of CYP1A1 and CYP2D6 polymorphisms on the risk of head and neck squamous... DisGeNET Detail
LR analysis revealed that subjects carrying CYP1A1 TC/CC + GSTM1 null genotypes had 3.52-fold (P < 0... DisGeNET Detail
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For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... DisGeNET Detail
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The association between CYP1A1 genetic polymorphisms and coronary artery disease in the Uygur and Ha... DisGeNET Detail
Moreover, it also shows the effect of smoking-gene interaction on CAD risk, where the CYP1A1 MspI po... DisGeNET Detail
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However, available data collected by the study failed to reveal remarkable associations of GC or HC ... DisGeNET Detail
For cytochrome P450 enzymes 1 (CYP1) family, the expression of CYP1A2 was decreased 90% in HCC, 80% ... DisGeNET Detail
Association between the CYP1A1 polymorphisms and hepatocellular carcinoma: a meta-analysis. DisGeNET Detail
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The CYP1A1-3801-CC (AOR = 0.47, 95% CI: 0.23, 0.94) and CYP2C9-430-CT (AOR = 0.82, 95% CI: 0.68, 0.9... DisGeNET Detail
The CYP1A1-3801-CC (AOR = 0.47, 95% CI: 0.23, 0.94) and CYP2C9-430-CT (AOR = 0.82, 95% CI: 0.68, 0.9... DisGeNET Detail
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2,3,7,8-Tetrachlorodibenzo-p-dioxin modulates estradiol-induced aldehydic DNA lesions in human breas... DisGeNET Detail
Here, we focus on recent advances in the understanding of molecular mechanisms that mediate this cro... DisGeNET Detail
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Association between cytochrome P450 1A1 (CYP1A1) gene polymorphisms and the risk of renal cell carci... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs1065827 dbSNP
Genome
hg38
Position
chr15:74,719,542-74,725,536
Variant Type
snv
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