Neoplasms, Germ Cell and Embryonal

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Information
Disease name
Neoplasms, Germ Cell and Embryonal
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04222972 Active, not recruiting Phase 3 A Study of Pralsetinib Versus Standard of Care for First-Line Treatment of Advanced Non-Small Cell Lung Cancer (NSCLC) July 24, 2020 June 30, 2025
NCT03911388 Active, not recruiting Phase 1 HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors September 12, 2019 September 1, 2026
NCT05592743 Available Vorasidenib Expanded Access Program
NCT02863003 Completed Multicenter Database of Patients With Germ Cell Tumor September 2016 December 2020
NCT03012620 Completed Phase 2 Secured Access to Pembrolizumab for Patients With Selected Rare Cancer Types July 5, 2017 December 14, 2023
NCT00393861 Completed Phase 2 Study of Oxaliplatin Plus Bevacizumab in Germ Cell Tumor Patients October 2006 November 2014
NCT03403777 Completed Phase 2 Avelumab in Refractory Testicular Germ Cell Cancer. November 15, 2017 February 28, 2019
NCT03037385 Completed Phase 1/Phase 2 Phase 1/2 Study of the Highly-selective RET Inhibitor, Pralsetinib (BLU-667), in Participants With Thyroid Cancer, Non-Small Cell Lung Cancer, and Other Advanced Solid Tumors March 17, 2017 March 21, 2024
NCT00611962 Completed Phase 2 Phase II Study of Oxaliplatine-Paclitaxel in Patients With Metastatic Germ Cell Tumor Refractory to Cisplatin December 2000 March 2004
NCT02679950 Completed Understanding the Molecular and Genetic Differences Between Germ Cell Tumor at the Time of the Initial Diagnosis and at Late Relapse November 20, 2015 April 25, 2017
NCT04657315 Completed Phase 1/Phase 2 Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients June 24, 2020 December 22, 2022
NCT04949282 Recruiting Spanish Series of Patients Treated With the Radionuclide Lutetium177 May 10, 2021 December 31, 2035
NCT02859415 Terminated Phase 1/Phase 2 Continuous 24h Intravenous Infusion of Mithramycin, an Inhibitor of Cancer Stem Cell Signaling, in People With Primary Thoracic Malignancies or Carcinomas, Sarcomas or Germ Cell Neoplasms With Pleuropulmonary Metastases August 8, 2019 December 1, 2021
NCT02533765 Unknown status Phase 2 Olaparib as Salvage Treatment for Cisplatin-resistant Germ Cell Tumor September 11, 2015 June 2021
NCT04697446 Unknown status External Control, Observational, Retrospective Study Comparing Pralsetinib to Best Available Therapy in Patients With RET-Fusion Positive NSCLC December 1, 2020 October 31, 2021
NCT02839694 Withdrawn Phase 1 Adjuvant Oral Decitabine and Tetrahydrouridine With or Without Celecoxib in People Undergoing Pulmonary Metastasectomy July 7, 2016 April 26, 2017
MeSH unique ID (MeSH (Medical Subject Headings))
D009373