Annotation Detail

Information
Associated Genes
CYP1A1
Associated Variants
CYP1A1 MUTATION
CYP1A1 MUTATION
Associated Disease
Malignant neoplasm of breast
Source Database
DisGeNET
Description
Here, we focus on recent advances in the understanding of molecular mechanisms that mediate this crosstalk repression, and particularly on how ERα represses the AhR target gene CYP1A1, and could subsequently promote breast cancer.
Pubmed
25257533
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.103886884743067
Drugs