hypospadias
Information
- Disease name
- hypospadias
- Disease ID
- DOID:10892
- Description
- "A physical disorder characterized by an abnormally placed urethral opening on the underside of the penis or on the perineum." [url:http\://en.wikipedia.org/wiki/Hypospadias, url:http\://ghr.nlm.nih.gov/glossary=hypospadias]
Disease area statistics
Chromosome band
| Gene symbol | Chromosome | Start | Stop | The number of variant |
|---|---|---|---|---|
| AR | X | 67,544,021 | 67,730,619 | 26 |
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT03102554 | Active, not recruiting | N/A | Genetics of Differences of Sex Development and Hypospadias | January 1, 2018 | December 2025 |
| NCT05936853 | Active, not recruiting | N/A | The EPigenetic Consequences in Children of Intravenous vs Volatile Anaesthesia for Surgery (EPIVA) | August 3, 2023 | July 1, 2025 |
| NCT02861950 | Active, not recruiting | Phase 4 | Does Caudal Block Increase the Incidence of Urethrocutaneous Fistula Formation Following Hypospadias Repair in Infants? | May 24, 2017 | December 31, 2023 |
| NCT02040389 | Completed | N/A | Visual Guidelines and Tutoring in Pediatric Urological Surgery | March 2014 | June 2016 |
| NCT06187363 | Completed | Redo Repair in Disrupted Hypospadias | January 1, 2019 | January 1, 2022 | |
| NCT02103712 | Completed | Long Term Outcome of Hypospadias Repair | October 1, 2012 | September 30, 2013 | |
| NCT05960123 | Completed | N/A | Evaluation of TIP Urethroplasty With Spongioplasty-Dartosoraphy Reinforcement in Pediatric Hypospadias | April 1, 2019 | May 30, 2023 |
| NCT02164682 | Completed | The Effect of Caudal Block on the Postoperative Complications in Pediatric Patients After Hypospadias Repair | June 2014 | January 2015 | |
| NCT02495090 | Completed | N/A | Hypospadias and Exome: Identification of New Genes for Familial Hypospadias | November 13, 2014 | April 24, 2024 |
| NCT05727969 | Completed | N/A | Dexmedetomidine Infusion and Surgical Pleth Index In Pediatrics | January 15, 2023 | December 15, 2023 |
| NCT02593903 | Completed | N/A | Antibiotic Use Following Distal and Mid-shaft Hypospadias Repair | March 4, 2014 | April 2018 |
| NCT02752308 | Completed | Phase 2/Phase 3 | Effectiveness of Caudal Epidural Block on Intraoperative Blood Loss During Hypospadias Repair | September 2014 | March 2015 |
| NCT02805491 | Completed | Influence of Pesticide Exposure on the Occurrence of Hypospadias in Newborns in Picardie | March 3, 2011 | December 20, 2014 | |
| NCT02848157 | Completed | Phase 4 | Effects of Dexmedetomidine as Adjunct to Pudendal Block for Pediatric Penile Surgery | June 17, 2016 | March 24, 2017 |
| NCT02851290 | Completed | N/A | Effect of Caudal and Penile Block on Hypospadias Repair Complications | July 2016 | May 19, 2023 |
| NCT03275519 | Completed | N/A | Antibiotic Use in Distal Hypospadias Repair | January 19, 2015 | April 19, 2017 |
| NCT03575377 | Completed | N/A | Opioid Use, Storage, and Disposal Among Pediatric Patients After Surgery | June 7, 2018 | December 31, 2018 |
| NCT01875640 | Completed | Decision Support for Parents Receiving Information About Child's Rare Disease | June 2013 | December 2017 | |
| NCT04755803 | Completed | A Prospective Registry of Patients With Congenital Penile Anomalies | July 10, 2020 | March 30, 2023 | |
| NCT04699318 | Completed | N/A | Urethrocutaneous Fistula Rate After Double Dartos and Single Dartos Tubularized Incised Plate Urethroplasty | August 1, 2017 | January 31, 2018 |
| NCT04668183 | Completed | Ultrasound-guided PNB and DPNB for Pediatric Distal Hypospadias Surgery | November 1, 2019 | August 1, 2020 | |
| NCT03677453 | Completed | N/A | Interactive Perioperative Teaching Platform (IPTP) | October 10, 2018 | November 30, 2020 |
| NCT05632536 | Completed | N/A | Comparison of Analgesic Efficacy of ESP Block and Caudal Block in Patients Undergoing Hypospadias Surgery | December 21, 2022 | December 19, 2023 |
| NCT06275646 | Completed | N/A | Comparison Of Outcome Of Different Layers in Hypospadias Surgery | January 1, 2022 | April 1, 2023 |
| NCT03838458 | Completed | Molecular and Structural Comparison of Hypospadic and Normal Children Prepuces | January 7, 2019 | March 10, 2020 | |
| NCT03902249 | Completed | Phase 4 | Effect of Intravenous Dexamethasone With Pudendal Nerve Block on Postoperative Pain in Pediatric Hypospadias Repair | January 1, 2017 | December 31, 2018 |
| NCT01370798 | Completed | Phase 3 | Local Oestrogen Versus Placebo as Preoperative Treatment in Patients With Severe Hypospadias: Effects on Post-operative Complications | May 26, 2011 | September 18, 2017 |
| NCT05253456 | Completed | Phase 2 | Modified Second Layer Repair for Distal Penile Hypospadias | March 1, 2018 | September 2, 2020 |
| NCT05144659 | Completed | N/A | Evaluation of Double Faced Transverse Preputial Onlay Island Flap for Hypospadias Repair in Pediatrics | May 1, 2019 | February 28, 2021 |
| NCT04215874 | Completed | Caudal Epidural Block and DPNB in Hypospadias | April 14, 2019 | December 15, 2019 | |
| NCT04239066 | Completed | N/A | Penile Ischemia for Hypospadias Repair and The Patients and Surgeons Reported Outcomes | September 1, 2017 | December 1, 2019 |
| NCT05056311 | Completed | N/A | Engaging Families to Improve the Care of Patients With Hypospadias | June 9, 2021 | October 6, 2022 |
| NCT04876976 | Completed | Phase 2/Phase 3 | Isoamyl 2-Cyanoacrylate in the Urethro-cutaneous Fistula Repair | January 1, 2017 | January 1, 2020 |
| NCT03593720 | Enrolling by invitation | Glans Size in Hypospadias Compared to Normal | July 25, 2018 | December 29, 2023 | |
| NCT05569863 | Not yet recruiting | Identification of Hypospadias Parameters Using Digital Photography and Artificial Intelligence | November 14, 2022 | December 31, 2023 | |
| NCT03698721 | Not yet recruiting | Urothelium Tissue Engineering Using Biopsies From Transurethral Resection of Prostate | October 2018 | October 2026 | |
| NCT04533477 | Not yet recruiting | N/A | Reconstructing Forked Corpus Spongiosum in Hypospadias Repair | March 1, 2023 | September 30, 2023 |
| NCT06180018 | Not yet recruiting | N/A | Modified TIP (Snodgrass) Using Interrupted Sutures in Hypospadias | January 1, 2024 | March 30, 2026 |
| NCT06410482 | Not yet recruiting | N/A | Analgesia in Pediatric Hypospadias Surgeries | May 2024 | June 2025 |
| NCT05666206 | Recruiting | N/A | Efficacy of Fibrin Sealant in Hypospadias Surgery | January 1, 2022 | December 1, 2024 |
| NCT06405763 | Recruiting | N/A | Snodgrass Versus Grafted Snodgrass Repair in Narrow Urethral Plate in Distal Penile Hypospadias | December 11, 2023 | December 10, 2024 |
| NCT06417060 | Recruiting | N/A | Caudal Anesthesia Versus Local Anesthesia in Hypospadias | May 25, 2023 | May 26, 2024 |
| NCT05319782 | Recruiting | N/A | Long-term Assesment of Patients Operated for Hypospadias in Their Childhood : Urinary, Aesthetical, Sexual and Psycho-social Consequences | May 10, 2023 | May 2024 |
| NCT02512887 | Recruiting | N/A | Caudal vs Local Anesthesia in Hypospadias | July 2016 | January 2024 |
| NCT05922605 | Recruiting | Phase 4 | Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias | June 20, 2023 | May 1, 2025 |
| NCT05837000 | Recruiting | Phase 4 | Dexmedetomidine, Ketamine and Magnesium Sulphate in Caudal Block for Hypospadias Repair | May 15, 2023 | October 25, 2024 |
| NCT04142632 | Recruiting | Long Term Follow-up for Hypospadias | February 17, 2020 | February 17, 2026 | |
| NCT05093166 | Suspended | Phase 1/Phase 2 | Clinical Trial to Assess the Safety and Efficacy of Investigational Product in Patients Due to Hypospadias Treatment Failure | November 26, 2021 | December 2024 |
| NCT05708989 | Suspended | Phase 4 | Caudal vs. Pudendal Block in Peds GU | March 6, 2023 | May 2025 |
| NCT04826484 | Terminated | Phase 3 | Opioid Reduction Initiative During Outpatient Pediatric Urologic Procedures Using Exparel | October 1, 2021 | April 26, 2023 |
| NCT02162810 | Terminated | N/A | Effect of Steroids on Post-Operative Complications Following Proximal Hypospadias Repair | May 2014 | May 2022 |
| NCT03911635 | Unknown status | N/A | Selective Criteria and a Modified Technique of Applying "URAGPI" Technique for More Proximal Degree of Hypospadias | April 1, 2020 | March 1, 2021 |
| NCT04196400 | Unknown status | Early Phase 1 | The Role of Local Long Acting Corticosteroid Injection in Hypospadias Surgery. | December 1, 2019 | March 1, 2021 |
| NCT05123833 | Unknown status | N/A | The Optimal Urethral Coverage in Hypospadias Repair: Dartos Fascia Versus Tunica Vaginalis Flap? A Randomized Controlled Trial | August 1, 2021 | August 1, 2022 |
| NCT02497963 | Unknown status | N/A | Foreskin Graft Tubularized Incised Plate Urethroplasty vs Tubularized Incised Plate for Primary Hypospadias (FGTIP-TIP) | August 2015 | March 2017 |
| NCT02096159 | Unknown status | N/A | Prophylactic Antibiotics or Placebo After Hypospadias Repair | March 2014 | June 2023 |
| NCT05032222 | Unknown status | The Role of "Hypospadias Objective Scoring Evaluation" (HOSE) and Uroflowmetry in Evaluation of Successful Hypospadias Repair | May 1, 2021 | May 1, 2023 | |
| NCT04671992 | Unknown status | N/A | Out Of-plane Technique Against In-plane for Caudal Block | December 1, 2020 | April 15, 2021 |
| NCT04423107 | Unknown status | Phase 3 | Assessment of Postop Hypospadias Pain | July 1, 2020 | January 2023 |
| NCT04479371 | Withdrawn | Phase 1 | Liposomal Bupivacaine vs Standard Penile Block for Hypospadias Repair | July 2021 | July 30, 2023 |
| NCT01762007 | Withdrawn | The Change of the Detrusor Thickness After Hypospadias Repair - Comparison With the Normal Control Group | November 2012 | July 2013 | |
| NCT03685955 | Withdrawn | Efficacy of Amniotic Membranes in Complex Genitourinary Reconstruction | March 2020 | March 2021 |
- Disase is a (Disease Ontology)
- DOID:0080015
- Cross Reference ID (Disease Ontology)
- ICD10CM:Q54
- Cross Reference ID (Disease Ontology)
- MESH:D007021
- Cross Reference ID (Disease Ontology)
- MIM:146450
- Cross Reference ID (Disease Ontology)
- MIM:300633
- Cross Reference ID (Disease Ontology)
- MIM:300758
- Cross Reference ID (Disease Ontology)
- MIM:300856
- Cross Reference ID (Disease Ontology)
- NCI:C40341
- Cross Reference ID (Disease Ontology)
- ORDO:440
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:156968008
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0848558
- Exact Synonym (Disease Ontology)
- familial hypospadias
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0000047
- OMIM Phenotype Series Number (OMIM)
- PS300633
- ICD10 preferred id (Insert disease from ICD10)
- D0013884
- ICD10 class code (Insert disease from ICD10)
- Q54
- MeSH unique ID (MeSH (Medical Subject Headings))
- D007021