Annotation Detail

Information
Associated Genes
CYP1A1
Associated Variants
CYP1A1 MUTATION
CYP1A1 MUTATION
Associated Disease
Lung diseases
Source Database
DisGeNET
Description
Our novel results on estradiol metabolism in fetal and early postnatal lung in the context of hyperoxia indicate CYP1a1 as a potential mechanism for the protective effect of estradiol in hyperoxia-exposed immature lung, which may help explain the sex difference in neonatal lung diseases.
Pubmed
25399436
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
8
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000271441872080303
Drugs