Microsatellite Instability

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Information
Disease name
Microsatellite Instability
Disease ID
Description
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT03228667 Active, not recruiting Phase 2 QUILT-3.055: A Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With Immune Checkpoint Inhibitors December 11, 2018 December 2024
NCT05257057 Active, not recruiting Frequency of Endometrial Cancer Precursors Associated With Lynch Syndrome May 8, 2019 December 2024
NCT03519412 Active, not recruiting Phase 2 Pembrolizumab in MMR-Proficient Metastatic Colorectal Cancer Pharmacologically Primed to Trigger Hypermutation Status January 23, 2019 December 2024
NCT05511688 Active, not recruiting National Cohort of Colorectal Cancers With Microsatellite Instability March 22, 2017 October 2022
NCT06238193 Completed Molecular Characteristics of Early-onset Compared With Late-onset Colorectal Cancer January 1, 2003 January 1, 2024
NCT03053466 Completed Phase 1 APL-501 Study for Select Advanced or Relapsed/Recurrent Solid Tumors March 27, 2017 February 25, 2022
NCT03841110 Completed Phase 1 FT500 as Monotherapy and in Combination With Immune Checkpoint Inhibitors in Subjects With Advanced Solid Tumors February 15, 2019 November 15, 2022
NCT03012581 Completed Phase 2 Secured Access to Nivolumab for Adult Patients With Selected Rare Cancer Types June 16, 2017 November 11, 2023
NCT03935893 Recruiting Phase 2 Adoptive Transfer of Tumor Infiltrating Lymphocytes for Advanced Solid Cancers December 3, 2019 June 30, 2037
NCT04817826 Recruiting Phase 2 TremelImumab aNd Durvalumab For the Non-operatIve Management (NOM) of MSI-high Resectable GC/GEJC. April 1, 2021 April 30, 2025
NCT03594448 Recruiting Detection of MSI in Circulating Tumor DNA of Colorectal Carcinoma Patients September 5, 2018 September 5, 2025
NCT03767348 Recruiting Phase 2 Study of RP1 Monotherapy and RP1 in Combination With Nivolumab September 20, 2017 November 2024
NCT03827044 Terminated Phase 3 Avelumab Plus 5-FU Based Chemotherapy as Adjuvant Treatment for Stage 3 MSI-High or POLE Mutant Colon Cancer August 31, 2018 January 5, 2022
NCT04106167 Terminated Long-term, Non-interventional, Observational Study Following Treatment With Fate Therapeutics FT500 Cellular Immunotherapy June 11, 2019 August 11, 2023
NCT04191252 Unknown status Genetic Mutation in Epithelial Ovarian Cancer December 19, 2019 January 1, 2023
NCT04191226 Unknown status Genetic Mutation in Recurrent Cervical Cancer December 19, 2019 January 1, 2023
NCT03744962 Unknown status MSI in Circulatory DNA of Endometrial Cancer November 10, 2018 December 23, 2020
NCT03447431 Unknown status Aberrant Splicings Due to Microsatellite Instability in Colorectal Cancer : Physiopathological and Clinical Impact April 5, 2018 February 2021
NCT02966587 Withdrawn Phase 2 Durvalumab in Treating Patients With Metastatic Hormone-Resistant Prostate Cancer May 15, 2018 May 15, 2023
MeSH unique ID (MeSH (Medical Subject Headings))
D053842