Annotation Detail
Information
- Associated Genes
- CYP1A1
- Associated Variants
-
CYP1A1 MUTATION
CYP1A1 MUTATION - Associated Disease
- Carcinogenicity
- Source Database
- DisGeNET
- Description
- In conclusion, the present work shows a strong evidence that MET inhibits the DMBA-mediated carcinogenicity and adduct formation by inhibiting the expression of CYP1A1 through an AhR ligand-independent mechanism.
- Pubmed
- 25697376
- Section of the abstract supporting the evidence
- NAD(P)H
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 10
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs