Annotation Detail

Information
Associated Genes
CYP1A1
Associated Variants
CYP1A1 MUTATION
CYP1A1 MUTATION
Associated Disease
Squamous cell carcinoma of the head and neck
Source Database
DisGeNET
Description
LR analysis revealed that subjects carrying CYP1A1 TC/CC + GSTM1 null genotypes had 3.52-fold (P < 0.001) increase the risk of head and neck squamous cell carcinoma (HNSCC).
Pubmed
25724184
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
7
Original source reporting the Gene Disease association
BeFree,GAD
DisGENET score for the Gene Disease association
0.00535289257148537
Drugs