Annotation Detail

Information
Associated Genes
CYP1A1
Associated Variants
CYP1A1 MUTATION
CYP1A1 MUTATION
Associated Disease
colorectal cancer
Source Database
DisGeNET
Description
The CYP1A1-3801-CC (AOR = 0.47, 95% CI: 0.23, 0.94) and CYP2C9-430-CT (AOR = 0.82, 95% CI: 0.68, 0.99) genotypes were associated with decreased risk, and the GSTM1-K173N-CG (AOR = 1.99, 95% CI: 1.21, 3.25) genotype was associated with an increased risk of colorectal cancer.
Pubmed
20937634
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.0715102358405033
Year of publication
2010
Drugs