chr15:99191768:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr15:99,191,768-99,507,759
hg38 chr15:98,648,539-98,964,530 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 renal cell carcinoma NA BeFree Detail
0.004 squamous cell carcinoma NA BeFree,LHGDN Detail
0.003 hypertrophic cardiomyopathy NA LHGDN Detail
0.120 Neoplastic Cell Transformation NA CTD_human Detail
0.002 intracranial arteriosclerosis NA GAD Detail
0.002 brain ischemia NA GAD Detail
0.001 Malignant tumor of cervix NA BeFree Detail
0.002 chorioamnionitis NA GAD Detail
<0.001 Congenital chromosomal disease NA BeFree Detail
0.011 Colonic Neoplasms NA GAD,LHGDN Detail
0.002 Colonic Polyps NA GAD Detail
0.006 colorectal carcinoma Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorec... BeFree 25090459 Detail
0.006 colorectal carcinoma MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal ... BeFree 25474488 Detail
0.016 Colorectal Neoplasms NA GAD,LHGDN Detail
0.003 craniopharyngioma NA LHGDN Detail
<0.001 craniosynostosis NA BeFree Detail
<0.001 Cushing syndrome IGF1R amplification was detected in an adrenocortical carcinoma that was diagnos... BeFree 25110710 Detail
<0.001 Phyllodes Tumor Taken together, this study defines the genomic landscape underlying phyllodes tu... BeFree 25593300 Detail
0.003 Cessation of life NA LHGDN Detail
<0.001 Presenile dementia Insulin-like growth factor-I receptor stimulating activity is associated with de... BeFree 24820016 Detail
<0.001 Mental Depression A genetic association analysis of polymorphisms in 10 genes contributing to the ... BeFree 25836355 Detail
<0.001 depressive disorder A genetic association analysis of polymorphisms in 10 genes contributing to the ... BeFree 25836355 Detail
0.001 diabetes mellitus Moreover, patients with DM highly expressed IGF-1R in tumor tissues, which was a... BeFree 25617986 Detail
0.080 Diabetes Mellitus, Experimental NA RGD Detail
0.088 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree,GAD,RGD Detail
0.080 Diabetic Nephropathy NA RGD Detail
0.080 diabetic retinopathy NA RGD Detail
0.004 Dwarfism NA BeFree Detail
0.120 Endometrial Neoplasms NA CTD_human Detail
0.008 Esophageal Neoplasms NA BeFree,GAD,LHGDN Detail
0.002 esophagitis NA GAD Detail
<0.001 Exanthema NA BeFree Detail
0.004 Failure to Thrive IGF1R aberrations lead to intrauterine and postnatal growth failure, microcephal... BeFree 24863809 Detail
0.004 Failure to Thrive Human deficiency in IGF1R is involved in growth failure, microcephaly, mental re... BeFree 25238791 Detail
0.122 Fetal Growth Retardation NA CTD_human,GAD Detail
0.002 Fetal Membranes, Premature Rupture NA GAD Detail
0.003 gastrinoma NA BeFree,LHGDN Detail
0.003 gastroesophageal reflux disease NA BeFree,GAD Detail
0.004 glioblastoma NA BeFree,LHGDN Detail
0.006 Glioma MicroRNA-7 directly targets insulin-like growth factor 1 receptor to inhibit cel... BeFree,LHGDN 25394492 Detail
0.006 Glioma MiR-323-5p acts as a tumor suppressor by targeting the insulin-like growth facto... BeFree,LHGDN 25556445 Detail
<0.001 granulosa cell tumor Epidermal growth factor receptor (EGFR), HER2 and insulin-like growth factor-1 r... BeFree 24206174 Detail
0.001 Graves Disease NA BeFree Detail
0.120 Growth Disorders NA CTD_human Detail
0.003 Head and Neck Neoplasms NA LHGDN Detail
<0.001 Heart failure NA BeFree Detail
<0.001 congestive heart failure NA BeFree Detail
<0.001 Ventricular Septal Defects NA BeFree Detail
<0.001 hepatitis B The concurrent expression of OCT4/NANOG/IGFIR was mostly confined to hepatitis B... BeFree 25564572 Detail
<0.001 Von Hippel-Lindau syndrome NA BeFree Detail
<0.001 hyperinsulinism NA BeFree Detail
0.080 Hyperphagia NA RGD Detail
0.002 Hyperplasia NA GAD Detail
0.088 Hypertensive disease These data suggest that Rg5 plays a novel role as an IGF-1R agonist, promoting t... BeFree,GAD,RGD 25391655 Detail
<0.001 pulmonary hypertension NA BeFree Detail
0.080 hyperthyroidism NA RGD Detail
<0.001 Inflammatory Bowel Diseases NA BeFree Detail
<0.001 Keloid NA BeFree Detail
<0.001 Kidney Failure, Acute NA BeFree Detail
0.080 Kidney Neoplasm NA BeFree,RGD Detail
0.002 Premature Obstetric Labor NA GAD Detail
0.006 Fibroid Tumor NA BeFree,LHGDN Detail
0.001 leukemia Upregulation of IGF1R by mutant RAS in leukemia and potentiation of RAS signalin... BeFree 25186968 Detail
0.001 leukemia Furthermore, IGF-1, ligand of IGF-1R, induced the up-regulation of IGF-1R and in... BeFree 25448401 Detail
<0.001 chronic lymphocytic leukemia These data suggest that IGF1R may play an important role in CLL biology, in part... BeFree 25786252 Detail
0.001 Acute lymphocytic leukemia The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of... BeFree 25648584 Detail
0.004 Leukemia, Myelocytic, Acute SUMOylation of insulin-like growth factor 1 receptor, promotes proliferation in ... BeFree,LHGDN 25448401 Detail
<0.001 Myeloid Leukemia, Chronic The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of... BeFree 25648584 Detail
<0.001 lipodystrophy NA BeFree Detail
0.080 Liver Cirrhosis, Experimental NA RGD Detail
0.006 Liver neoplasms NA BeFree,GAD,LHGDN Detail
0.120 Lung diseases NA CTD_human Detail
0.002 Chronic Obstructive Airway Disease NA GAD Detail
0.002 Lymphoma, Non-Hodgkin NA GAD Detail
0.002 Malignant neoplasm of stomach Additionally, downregulation of miR-503 in the cisplatin (DDP)-resistant gastric... BeFree 24931256 Detail
0.002 Malignant neoplasm of stomach Silencing insulin-like growth factor-1 receptor expression inhibits gastric canc... BeFree 25339573 Detail
0.002 Malignant neoplasm of stomach Phosphorylated insulin-like growth factor-1 receptor expression predicts poor pr... BeFree 25348345 Detail
0.002 Malignant neoplasm of stomach Our findings suggested that hsa-miR-143 could modulate cisplatin resistance of h... BeFree 25492481 Detail
0.002 Malignant neoplasm of stomach This study suggests that miR-133a is downregulated in GC and functions as a tumo... BeFree 25780292 Detail
0.080 Malocclusion NA RGD Detail
0.002 Animal Mammary Neoplasms NA GAD Detail
0.004 medulloblastoma Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apopto... BeFree,LHGDN 25885794 Detail
0.002 melanoma NA BeFree Detail
<0.001 Mesothelioma NA BeFree Detail
0.002 Metaplasia NA GAD Detail
<0.001 microcephaly Microcephaly should be considered in the evaluation of SGA patients, because it ... BeFree 25040157 Detail
<0.001 Micrognathism NA BeFree Detail
0.001 Monosomy The distal partial trisomy 15q included the insulin-like growth factor 1 recepto... BeFree 25871641 Detail
0.003 Mouth Neoplasms NA LHGDN Detail
0.006 multiple myeloma Our study suggests that combination treatment with AZD8055 and IGF1R-blocking ag... BeFree,GAD 25172964 Detail
<0.001 spinal muscular atrophy In the present study, we report that insulin-like growth factor-1 receptor (Igf-... BeFree 26311784 Detail
0.080 myocardial infarction NA RGD Detail
0.031 Neoplasm Metastasis Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growt... BeFree,LHGDN 24809702 Detail
0.031 Neoplasm Metastasis microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro ... BeFree,LHGDN 25096247 Detail
0.031 Neoplasm Metastasis Overexpression of p-IGF1R protein was associated with lymph metastasis, clinical... BeFree,LHGDN 25348345 Detail
0.031 Neoplasm Metastasis Conversion in expression of the studied proteins from the primary tumor to metas... BeFree,LHGDN 25417118 Detail
0.031 Neoplasm Metastasis These results may improve the current understanding of the basic molecular mecha... BeFree,LHGDN 25749031 Detail
0.031 Neoplasm Metastasis In view of the present results, it was concluded that TGF-β1, IGF-I/IGF-IR and V... BeFree,LHGDN 25824321 Detail
0.002 nephroblastoma This review highlights selected examples of a series of tumor suppressors, inclu... BeFree 24863809 Detail
<0.001 neurilemmoma NA BeFree Detail
0.006 neuroblastoma NA BeFree,LHGDN Detail
<0.001 neurofibromatosis 1 NA BeFree Detail
0.008 obesity NA BeFree,GAD Detail
0.003 osteoporosis NA LHGDN Detail
0.002 osteosarcoma microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro ... BeFree 25096247 Detail
0.002 ovarian carcinoma NA BeFree Detail
0.008 Pancreatic Neoplasm NA BeFree,GAD,LHGDN Detail
0.200 Parkinson disease NA CTD_human,RGD Detail
0.120 Peripheral neuropathy NA CTD_human Detail
0.003 pheochromocytoma NA BeFree,LHGDN Detail
<0.001 pituitary adenoma NA BeFree Detail
<0.001 Pituitary Diseases NA BeFree Detail
<0.001 Pituitary Neoplasms NA BeFree Detail
0.002 polycystic ovary syndrome NA GAD Detail
<0.001 polycythemia vera NA BeFree Detail
0.002 pre-eclampsia NA GAD Detail
0.003 Prostatic Neoplasms NA LHGDN Detail
<0.001 psoriasis NA BeFree Detail
<0.001 Psychotic Disorders NA BeFree Detail
0.120 Respiratory Insufficiency NA CTD_human Detail
0.006 retinopathy of prematurity NA BeFree,GAD,LHGDN Detail
0.002 rhabdomyosarcoma MiR-378a-3p over-expression in an RMS-derived cell line suppressed IGF1R express... BeFree 25427715 Detail
<0.001 Kaposi sarcoma NA BeFree Detail
0.002 schizophrenia NA GAD Detail
0.088 Diabetes Mellitus, Non-Insulin-Dependent The aim of our study was to investigate whether common polymorphisms in the gene... BeFree 15127203 Detail
<0.001 Severe mental retardation (I.Q. 20-34) NA BeFree Detail
0.120 Skin Neoplasms NA CTD_human Detail
0.002 Spinal Diseases NA GAD Detail
0.008 Stomach Neoplasms NA GAD,LHGDN Detail
0.002 Cerebrovascular accident NA GAD Detail
0.003 synovial sarcoma NA BeFree,LHGDN Detail
0.003 Testicular Neoplasms NA LHGDN Detail
<0.001 Trisomy NA BeFree Detail
<0.001 Unipolar Depression A genetic association analysis of polymorphisms in 10 genes contributing to the ... BeFree 25836355 Detail
<0.001 Uterine Fibroids NA BeFree Detail
<0.001 Virilism IGF1R amplification was detected in an adrenocortical carcinoma that was diagnos... BeFree 25110710 Detail
<0.001 Zollinger-Ellison syndrome NA BeFree Detail
<0.001 B-Cell Lymphomas Additionally, downregulation of miR-503 in the cisplatin (DDP)-resistant gastric... BeFree 24931256 Detail
<0.001 B-Cell Lymphomas The absence of Esr2 resulted in increased apoptosis, decreased B-cell lymphoma 2... BeFree 25885794 Detail
0.080 gestational diabetes NA RGD Detail
<0.001 essential hypertension NA BeFree Detail
0.080 alcoholic neuropathy NA RGD Detail
<0.001 Left Ventricular Hypertrophy NA BeFree Detail
0.001 Small cell carcinoma of lung NA BeFree Detail
0.002 Premature Birth NA GAD Detail
0.001 Adenocarcinoma of lung (disorder) Our results suggest that TM4SF4 overexpression in lung carcinoma cells results i... BeFree 25344917 Detail
<0.001 esophageal carcinoma NA BeFree Detail
<0.001 Secondary malignant neoplasm of lung NA BeFree Detail
<0.001 Neurofibromatoses NA BeFree Detail
0.001 Russell-Silver syndrome NA BeFree Detail
0.002 Tumor Progression We also found that high expression of IGF-1R was associated with advanced tumor ... BeFree 25175038 Detail
<0.001 Liposarcoma, Dedifferentiated NA BeFree Detail
<0.001 alveolar rhabdomyosarcoma NA BeFree Detail
<0.001 Rhabdomyosarcoma, Embryonal NA BeFree Detail
<0.001 Neuroectodermal Tumor, Primitive NA BeFree Detail
0.121 adrenocortical carcinoma We demonstrated amplification and overexpression of IGF1R gene in only one adren... BeFree,CTD_human 25110710 Detail
<0.001 Carcinoma, Endometrioid NA BeFree Detail
<0.001 mucoepidermoid carcinoma These results suggested that apicidin is an attractive chemotherapeutic agent ag... BeFree 25647264 Detail
<0.001 cholangiocarcinoma NA BeFree Detail
0.003 Nerve Sheath Tumors NA LHGDN Detail
<0.001 Neuroendocrine Tumors NA BeFree Detail
0.120 congenital diaphragmatic hernia NA CTD_human Detail
0.003 pancreatic carcinoma Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growt... BeFree 24809702 Detail
0.003 Gastrointestinal Stromal Tumors As a result, IGF1R and VEGFR are promising to be the novel therapeutic targets o... BeFree 25741136 Detail
<0.001 Papillary thyroid carcinoma Significantly less staining for IGF-1Rβ was observed in normal adjacent thyroid ... BeFree 25329702 Detail
0.080 coronary stenosis NA RGD Detail
0.012 Malignant neoplasm of lung The purpose of this study was to investigate the prognostic role of IGF-1R expre... BeFree,GAD 25081930 Detail
<0.001 age related macular degeneration NA BeFree Detail
<0.001 Carcinoma, Small Cell NA BeFree Detail
<0.001 Epithelial hyperplasia of skin NA BeFree Detail
<0.001 Acute respiratory failure NA BeFree Detail
0.003 Impaired glucose tolerance Novel heterozygous IGF1R mutation in two brothers with developing impaired gluco... BeFree,GAD 25153223 Detail
<0.001 Carcinoma breast stage IV NA BeFree Detail
<0.001 gastric adenocarcinoma NA BeFree Detail
<0.001 Malignant Childhood Neoplasm NA BeFree Detail
<0.001 Metastatic melanoma NA BeFree Detail
0.003 Cancer of Head and Neck NA BeFree,GAD Detail
<0.001 Liver and Intrahepatic Biliary Tract Carcinoma NA BeFree Detail
0.001 Squamous cell carcinoma of esophagus Assessment of insulin-like growth factor 1 receptor as an oncogene in esophageal... BeFree 25175038 Detail
0.001 Squamous cell carcinoma of esophagus Silencing of insulin-like growth factor-1 receptor enhances the radiation sensit... BeFree 25363593 Detail
<0.001 Adenocarcinoma Of Esophagus NA BeFree Detail
<0.001 Conventional (Clear Cell) Renal Cell Carcinoma NA BeFree Detail
<0.001 Solid tumour The insulin-like growth factor 1 receptor (IGF-1R) is up-regulated in many solid... BeFree 25448401 Detail
<0.001 laryngeal squamous cell carcinoma miR-375 suppresses IGF1R expression and contributes to inhibition of cell progre... BeFree 25184138 Detail
<0.001 Adenocarcinoma of pancreas NA BeFree Detail
<0.001 desmoplastic small round cell tumor NA BeFree Detail
0.001 cervix carcinoma NA BeFree Detail
<0.001 malignant fibrous histiocytoma NA BeFree Detail
0.005 Thyroid associated opthalmopathies NA LHGDN Detail
0.002 Precocious pubarche NA GAD Detail
<0.001 Premature adrenarche NA BeFree Detail
<0.001 Malignant neoplasm of liver NA BeFree Detail
<0.001 Multiple malignancy In addition, xanthoceraside inhibited the expression of the insulin-like growth ... BeFree 25116791 Detail
<0.001 Multiple malignancy Insulin-like growth factor-1 receptor (IGF-1R) is a tyrosine kinase receptor imp... BeFree 25175038 Detail
0.002 Malignant neoplasm of pancreas Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growt... BeFree 24809702 Detail
<0.001 Secondary malignant neoplasm of female breast NA BeFree Detail
<0.001 Nonorganic psychosis NA BeFree Detail
<0.001 Squamous cell carcinoma of tongue NA BeFree Detail
0.014 Malignant neoplasm of prostate NA BeFree,GAD Detail
<0.001 Hematopoietic Neoplasms NA BeFree Detail
0.003 Nijmegen breakage syndrome NA BeFree,LHGDN Detail
<0.001 Dysmorphic features NA BeFree Detail
<0.001 Trisomy 12 High IGF1R gene expression was significantly associated with IGHV unmutated (IGH... BeFree 25786252 Detail
0.001 endometrial carcinoma This study identifies NEDD4 as a putative oncogene in endometrial cancer that ma... BeFree 26193427 Detail
0.001 Secondary malignant neoplasm of liver NA BeFree Detail
<0.001 dementia Insulin-like growth factor-I receptor stimulating activity is associated with de... BeFree 24820016 Detail
<0.001 prostatic adenoma NA BeFree Detail
<0.001 Recurrent tumor The concurrent expression of OCT4/NANOG/IGFIR was mostly confined to hepatitis B... BeFree 25564572 Detail
0.003 Metabolic syndrome X NA BeFree,GAD Detail
<0.001 Hepatitis C, Chronic Insulin-like growth factor-1 mRNA isoforms and insulin-like growth factor-1 rece... BeFree 25852271 Detail
0.003 Malignant neoplasm of esophagus NA BeFree,GAD Detail
<0.001 Thyroid carcinoma NA BeFree Detail
0.001 Ewings sarcoma We showed that trabectedin may not only inhibit but also enhance the binding of ... BeFree 25609059 Detail
0.002 Squamous cell carcinoma of skin NA GAD Detail
0.002 Osteosarcoma of bone microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro ... BeFree 25096247 Detail
<0.001 Carcinoma of larynx NA BeFree Detail
0.008 Carcinogenesis Signalling through the insulin-like growth factor 1 receptor (IGF-1R) is implica... BeFree 25081930 Detail
0.008 Carcinogenesis Human deficiency in IGF1R is involved in growth failure, microcephaly, mental re... BeFree 25238791 Detail
0.008 Carcinogenesis The oncoprotein insulin-like growth factor-1 receptor (IGF-1R) has previously be... BeFree 25339573 Detail
0.010 prostate carcinoma NA BeFree Detail
0.003 Epithelial ovarian cancer NA BeFree,GAD Detail
<0.001 invasive cancer NA BeFree Detail
0.020 breast carcinoma Our data provide a strong rationale for targeting PR in combination with ER and ... BeFree 24469035 Detail
0.020 breast carcinoma Our study provides proof-of-concept that inhibiting the IGF1R compensatory respo... BeFree 25320355 Detail
0.020 breast carcinoma In both the primary cancers and the metastases, Claudin-4 was most frequently ex... BeFree 25417118 Detail
0.020 breast carcinoma Aberrant allele-switch imprinting of a novel IGF1R intragenic antisense non-codi... BeFree 25465188 Detail
0.007 Carcinoma of lung The purpose of this study was to investigate the prognostic role of IGF-1R expre... BeFree 25081930 Detail
<0.001 Malignant neoplasm of muscle NA BeFree Detail
0.002 Malignant neoplasm of gastrointestinal tract NA BeFree Detail
0.001 Secondary malignant neoplasm of lymph node NA BeFree Detail
0.004 colon carcinoma NA BeFree Detail
0.002 stomach carcinoma Additionally, downregulation of miR-503 in the cisplatin (DDP)-resistant gastric... BeFree 24931256 Detail
0.002 stomach carcinoma Silencing insulin-like growth factor-1 receptor expression inhibits gastric canc... BeFree 25339573 Detail
0.002 stomach carcinoma Phosphorylated insulin-like growth factor-1 receptor expression predicts poor pr... BeFree 25348345 Detail
0.002 stomach carcinoma Our findings suggested that hsa-miR-143 could modulate cisplatin resistance of h... BeFree 25492481 Detail
0.002 stomach carcinoma This study suggests that miR-133a is downregulated in GC and functions as a tumo... BeFree 25780292 Detail
<0.001 Carcinoma of bladder NA BeFree Detail
0.003 Central neuroblastoma NA BeFree Detail
<0.001 Malignant neoplasm of kidney NA BeFree Detail
<0.001 biliary tract cancer NA BeFree Detail
<0.001 malignant peripheral nerve sheath tumor NA BeFree Detail
0.120 Lewy Body Disease NA CTD_human Detail
<0.001 ring chromosome 15 syndrome NA BeFree Detail
<0.001 Chromosome 15q, trisomy The distal partial trisomy 15q included the insulin-like growth factor 1 recepto... BeFree 25871641 Detail
<0.001 Spots on skin NA BeFree Detail
<0.001 premalignant lesion NA BeFree Detail
<0.001 Invasive breast carcinoma NA BeFree Detail
<0.001 Rhabdoid Tumor of the Kidney These and their respective parent cell lines were tested for sensitivity to erlo... BeFree 24895459 Detail
0.001 Carcinogenicity NA BeFree Detail
<0.001 Advanced cancer Our study provides proof-of-concept that inhibiting the IGF1R compensatory respo... BeFree 25320355 Detail
0.080 Cardiomyopathies NA RGD Detail
0.004 Growth failure IGF1R aberrations lead to intrauterine and postnatal growth failure, microcephal... BeFree 24863809 Detail
0.004 Growth failure Human deficiency in IGF1R is involved in growth failure, microcephaly, mental re... BeFree 25238791 Detail
0.002 Microsatellite Instability NA GAD Detail
<0.001 cancer recurrence NA BeFree Detail
<0.001 Colorectal cancer metastatic NA BeFree Detail
0.005 Malignant neoplasm of ovary NA BeFree,GAD Detail
<0.001 respiratory failure Igf1r-deficient mice die at birth due to growth retardation and respiratory fail... BeFree 25238791 Detail
<0.001 Squamous cell carcinoma of the head and neck NA BeFree Detail
0.006 sarcoma NA BeFree,LHGDN Detail
<0.001 Atypical teratoid/rhabdoid tumor NA BeFree Detail
<0.001 major depressive disorder A genetic association analysis of polymorphisms in 10 genes contributing to the ... BeFree 25836355 Detail
0.002 Systemic arterial pressure NA GAD Detail
<0.001 Partial Trisomy The distal partial trisomy 15q included the insulin-like growth factor 1 recepto... BeFree 25871641 Detail
<0.001 Gastric Gastrointestinal Stromal Tumor NA BeFree Detail
<0.001 Invasive Carcinoma NA BeFree Detail
<0.001 pancreatic ductal adenocarcinoma NA BeFree Detail
<0.001 Sporadic Breast Carcinoma NA BeFree Detail
<0.001 Epithelioma NA BeFree Detail
<0.001 renal carcinoma NA BeFree Detail
0.163 Mammary Neoplasms In this study, MTB-IGFIR transgenic mice, which develop mammary tumors resulting... BeFree,CTD_human,GAD,LHGDN 25655427 Detail
0.163 Mammary Neoplasms Overexpression of IGF1R and FAK are closely associated with metastatic breast tu... BeFree,CTD_human,GAD,LHGDN 25749031 Detail
0.163 Mammary Neoplasms Inhibition of the type 1 insulin-like growth factor receptor (IGF1R) reduces the... BeFree,CTD_human,GAD,LHGDN 26100015 Detail
<0.001 Hepatocarcinogenesis NA BeFree Detail
<0.001 Cancer Cell Growth Mounting evidence has shown that the insulin-like growth factor-1 receptor (IGF-... BeFree 24909165 Detail
<0.001 Tumor Immunity IGFs can inhibit DC-mediated anti-tumor immunity through suppressing maturation ... BeFree 25592043 Detail
<0.001 Xenograft Model We used ESCC cell lines and a mouse xenograft model to detect the function of IG... BeFree 25175038 Detail
0.008 colorectal cancer Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorec... BeFree,GAD 25090459 Detail
0.008 colorectal cancer MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal ... BeFree,GAD 25474488 Detail
<0.001 Glioblastoma multiforme NA BeFree Detail
<0.001 Benign Prostatic Hyperplasia NA BeFree Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
0.362 Insulin-Like Growth Factor I, Resistance To NA BeFree,CTD_human,ORPHANET,UNIPROT Detail
<0.001 uterine corpus cancer This study identifies NEDD4 as a putative oncogene in endometrial cancer that ma... BeFree 26193427 Detail
0.002 coronary artery disease NA GAD Detail
<0.001 Precursor T-Cell Lymphoblastic Leukemia-Lymphoma The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of... BeFree 25648584 Detail
<0.001 Precursor Cell Lymphoblastic Leukemia Lymphoma The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of... BeFree 25648584 Detail
0.129 liver carcinoma Association of IGF1R polymorphisms with the development of HBV-related hepatocel... BeFree,CTD_human,GAD,LHGDN 24758241 Detail
0.129 liver carcinoma The expression of pluripotency-related genes is associated with early tumor recu... BeFree,CTD_human,GAD,LHGDN 25564572 Detail
0.129 liver carcinoma A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p and m... BeFree,CTD_human,GAD,LHGDN 25739014 Detail
0.129 liver carcinoma These findings indicate that the tumor-suppressor miR-1275 can control HCC tumor... BeFree,CTD_human,GAD,LHGDN 26160756 Detail
0.080 Acute kidney injury NA RGD Detail
0.002 Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified NA GAD Detail
0.003 myelodysplastic syndrome NA LHGDN Detail
0.120 Juvenile arthritis NA CTD_human Detail
<0.001 Triple Negative Breast Neoplasms These results may improve the current understanding of the basic molecular mecha... BeFree 25749031 Detail
<0.001 Triple Negative Breast Neoplasms In the current study, the prognostic and predictive values of serum transforming... BeFree 25824321 Detail
<0.001 Congenital Abnormality NA BeFree Detail
0.002 Spontaneous abortion NA GAD Detail
<0.001 acanthosis nigricans NA BeFree Detail
<0.001 acromegaly Significantly less staining for IGF-1Rβ was observed in normal adjacent thyroid ... BeFree 25329702 Detail
<0.001 acromegaly The distal partial trisomy 15q included the insulin-like growth factor 1 recepto... BeFree 25871641 Detail
0.012 adenocarcinoma Amplification of the insulin-like growth factor 1 receptor gene is a rare event ... BeFree,GAD,LHGDN 25110710 Detail
0.012 adenocarcinoma The IGF-IR/IR ratios varied from <1 to 12 in the selected cell lines; similar pa... BeFree,GAD,LHGDN 26026165 Detail
0.003 adenoma NA BeFree,GAD Detail
<0.001 Tumors of Adrenal Cortex In addition, IGF1R polymorphisms and abnormal microRNA expression did not correl... BeFree 25110710 Detail
0.202 Alzheimer's disease NA CTD_human,GAD,RGD Detail
<0.001 Anaplasia NA BeFree Detail
0.003 Anemia, Sickle Cell NA BeFree,LHGDN Detail
0.003 Arteriovenous fistula NA LHGDN Detail
<0.001 rheumatoid arthritis NA BeFree Detail
<0.001 asbestosis NA BeFree Detail
0.006 atherosclerosis NA BeFree,LHGDN Detail
0.003 Bacteremia NA BeFree,GAD Detail
0.003 Barrett esophagus NA BeFree,GAD Detail
<0.001 Beckwith-Wiedemann syndrome NA BeFree Detail
0.003 Malignant neoplasm of urinary bladder NA BeFree,GAD Detail
0.002 Bone Diseases NA GAD Detail
0.003 Brain Neoplasms NA BeFree,GAD Detail
0.028 Malignant neoplasm of breast Our data provide a strong rationale for targeting PR in combination with ER and ... BeFree,GAD 24469035 Detail
0.028 Malignant neoplasm of breast Our study provides proof-of-concept that inhibiting the IGF1R compensatory respo... BeFree,GAD 25320355 Detail
0.028 Malignant neoplasm of breast In both the primary cancers and the metastases, Claudin-4 was most frequently ex... BeFree,GAD 25417118 Detail
0.028 Malignant neoplasm of breast Aberrant allele-switch imprinting of a novel IGF1R intragenic antisense non-codi... BeFree,GAD 25465188 Detail
<0.001 Breast Diseases NA BeFree Detail
0.003 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of endometrium This study identifies NEDD4 as a putative oncogene in endometrial cancer that ma... BeFree 26193427 Detail
<0.001 Malignant neoplasm of larynx NA BeFree Detail
<0.001 Malignant neoplasm of thyroid NA BeFree Detail
0.003 basal cell carcinoma NA LHGDN Detail
0.005 Non-small cell lung carcinoma Relevance of insulin-like growth factor 1 receptor gene expression as a prognost... BeFree 25081930 Detail
0.005 Non-small cell lung carcinoma Expression of insulin-like growth factor 1 receptor (IGF-1R) predicts poor respo... BeFree 25617986 Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independ... DisGeNET Detail
MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
IGF1R amplification was detected in an adrenocortical carcinoma that was diagnosed in a 46-year-old ... DisGeNET Detail
Taken together, this study defines the genomic landscape underlying phyllodes tumor development, sug... DisGeNET Detail
NA DisGeNET Detail
Insulin-like growth factor-I receptor stimulating activity is associated with dementia. DisGeNET Detail
A genetic association analysis of polymorphisms in 10 genes contributing to the IGF-I system (IGF1, ... DisGeNET Detail
A genetic association analysis of polymorphisms in 10 genes contributing to the IGF-I system (IGF1, ... DisGeNET Detail
Moreover, patients with DM highly expressed IGF-1R in tumor tissues, which was associated with a poo... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
IGF1R aberrations lead to intrauterine and postnatal growth failure, microcephaly, mental retardatio... DisGeNET Detail
Human deficiency in IGF1R is involved in growth failure, microcephaly, mental retardation and deafne... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MicroRNA-7 directly targets insulin-like growth factor 1 receptor to inhibit cellular growth and glu... DisGeNET Detail
MiR-323-5p acts as a tumor suppressor by targeting the insulin-like growth factor 1 receptor in huma... DisGeNET Detail
Epidermal growth factor receptor (EGFR), HER2 and insulin-like growth factor-1 receptor (IGF-1R) sta... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The concurrent expression of OCT4/NANOG/IGFIR was mostly confined to hepatitis B virus (HBV)-related... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
These data suggest that Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogene... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Upregulation of IGF1R by mutant RAS in leukemia and potentiation of RAS signaling inhibitors by smal... DisGeNET Detail
Furthermore, IGF-1, ligand of IGF-1R, induced the up-regulation of IGF-1R and increased the prolifer... DisGeNET Detail
These data suggest that IGF1R may play an important role in CLL biology, in particular in aggressive... DisGeNET Detail
The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of ALL (mostly T cell ... DisGeNET Detail
SUMOylation of insulin-like growth factor 1 receptor, promotes proliferation in acute myeloid leukem... DisGeNET Detail
The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of ALL (mostly T cell ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Additionally, downregulation of miR-503 in the cisplatin (DDP)-resistant gastric cancer cell line SG... DisGeNET Detail
Silencing insulin-like growth factor-1 receptor expression inhibits gastric cancer cell proliferatio... DisGeNET Detail
Phosphorylated insulin-like growth factor-1 receptor expression predicts poor prognosis of Chinese p... DisGeNET Detail
Our findings suggested that hsa-miR-143 could modulate cisplatin resistance of human gastric cancer ... DisGeNET Detail
This study suggests that miR-133a is downregulated in GC and functions as a tumor suppressor in vitr... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Estrogen Receptor-β Up-Regulates IGF1R Expression and Activity to Inhibit Apoptosis and Increase Gro... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Microcephaly should be considered in the evaluation of SGA patients, because it seems to favour the ... DisGeNET Detail
NA DisGeNET Detail
The distal partial trisomy 15q included the insulin-like growth factor 1 receptor gene involved with... DisGeNET Detail
NA DisGeNET Detail
Our study suggests that combination treatment with AZD8055 and IGF1R-blocking agents is a promising ... DisGeNET Detail
In the present study, we report that insulin-like growth factor-1 receptor (Igf-1r) gene expression ... DisGeNET Detail
NA DisGeNET Detail
Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. DisGeNET Detail
microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targe... DisGeNET Detail
Overexpression of p-IGF1R protein was associated with lymph metastasis, clinical stage, and adverse ... DisGeNET Detail
Conversion in expression of the studied proteins from the primary tumor to metastases was fairly fre... DisGeNET Detail
These results may improve the current understanding of the basic molecular mechanisms of TNBC metast... DisGeNET Detail
In view of the present results, it was concluded that TGF-β1, IGF-I/IGF-IR and VEGF-A overexpression... DisGeNET Detail
This review highlights selected examples of a series of tumor suppressors, including the breast canc... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targe... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
MiR-378a-3p over-expression in an RMS-derived cell line suppressed IGF1R expression and affected pho... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The aim of our study was to investigate whether common polymorphisms in the genes regulating the ear... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
A genetic association analysis of polymorphisms in 10 genes contributing to the IGF-I system (IGF1, ... DisGeNET Detail
NA DisGeNET Detail
IGF1R amplification was detected in an adrenocortical carcinoma that was diagnosed in a 46-year-old ... DisGeNET Detail
NA DisGeNET Detail
Additionally, downregulation of miR-503 in the cisplatin (DDP)-resistant gastric cancer cell line SG... DisGeNET Detail
The absence of Esr2 resulted in increased apoptosis, decreased B-cell lymphoma 2 (BCL2), and IGF-1 r... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Our results suggest that TM4SF4 overexpression in lung carcinoma cells results in resistance to radi... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We also found that high expression of IGF-1R was associated with advanced tumor progression. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We demonstrated amplification and overexpression of IGF1R gene in only one adrenocortical carcinoma,... DisGeNET Detail
NA DisGeNET Detail
These results suggested that apicidin is an attractive chemotherapeutic agent against salivary MEC a... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. DisGeNET Detail
As a result, IGF1R and VEGFR are promising to be the novel therapeutic targets of GISTs. DisGeNET Detail
Significantly less staining for IGF-1Rβ was observed in normal adjacent thyroid tissues of PTC patie... DisGeNET Detail
NA DisGeNET Detail
The purpose of this study was to investigate the prognostic role of IGF-1R expression in surgically ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Novel heterozygous IGF1R mutation in two brothers with developing impaired glucose tolerance. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Assessment of insulin-like growth factor 1 receptor as an oncogene in esophageal squamous cell carci... DisGeNET Detail
Silencing of insulin-like growth factor-1 receptor enhances the radiation sensitivity of human esoph... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The insulin-like growth factor 1 receptor (IGF-1R) is up-regulated in many solid tumors; therefore, ... DisGeNET Detail
miR-375 suppresses IGF1R expression and contributes to inhibition of cell progression in laryngeal s... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In addition, xanthoceraside inhibited the expression of the insulin-like growth factor-1 receptor (I... DisGeNET Detail
Insulin-like growth factor-1 receptor (IGF-1R) is a tyrosine kinase receptor implicated in the patho... DisGeNET Detail
Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
High IGF1R gene expression was significantly associated with IGHV unmutated (IGHV-UM) status (p<0.00... DisGeNET Detail
This study identifies NEDD4 as a putative oncogene in endometrial cancer that may augment activation... DisGeNET Detail
NA DisGeNET Detail
Insulin-like growth factor-I receptor stimulating activity is associated with dementia. DisGeNET Detail
NA DisGeNET Detail
The concurrent expression of OCT4/NANOG/IGFIR was mostly confined to hepatitis B virus (HBV)-related... DisGeNET Detail
NA DisGeNET Detail
Insulin-like growth factor-1 mRNA isoforms and insulin-like growth factor-1 receptor mRNA expression... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
We showed that trabectedin may not only inhibit but also enhance the binding of EWS-FLI1 to certain ... DisGeNET Detail
NA DisGeNET Detail
microRNA-194 suppresses osteosarcoma cell proliferation and metastasis in vitro and in vivo by targe... DisGeNET Detail
NA DisGeNET Detail
Signalling through the insulin-like growth factor 1 receptor (IGF-1R) is implicated in carcinogenesi... DisGeNET Detail
Human deficiency in IGF1R is involved in growth failure, microcephaly, mental retardation and deafne... DisGeNET Detail
The oncoprotein insulin-like growth factor-1 receptor (IGF-1R) has previously been shown to promote ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Our data provide a strong rationale for targeting PR in combination with ER and IGF1R in patients wi... DisGeNET Detail
Our study provides proof-of-concept that inhibiting the IGF1R compensatory response to mTOR inhibiti... DisGeNET Detail
In both the primary cancers and the metastases, Claudin-4 was most frequently expressed, followed by... DisGeNET Detail
Aberrant allele-switch imprinting of a novel IGF1R intragenic antisense non-coding RNA in breast can... DisGeNET Detail
The purpose of this study was to investigate the prognostic role of IGF-1R expression in surgically ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Additionally, downregulation of miR-503 in the cisplatin (DDP)-resistant gastric cancer cell line SG... DisGeNET Detail
Silencing insulin-like growth factor-1 receptor expression inhibits gastric cancer cell proliferatio... DisGeNET Detail
Phosphorylated insulin-like growth factor-1 receptor expression predicts poor prognosis of Chinese p... DisGeNET Detail
Our findings suggested that hsa-miR-143 could modulate cisplatin resistance of human gastric cancer ... DisGeNET Detail
This study suggests that miR-133a is downregulated in GC and functions as a tumor suppressor in vitr... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
The distal partial trisomy 15q included the insulin-like growth factor 1 receptor gene involved with... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
These and their respective parent cell lines were tested for sensitivity to erlotinib, IGFIR inhibit... DisGeNET Detail
NA DisGeNET Detail
Our study provides proof-of-concept that inhibiting the IGF1R compensatory response to mTOR inhibiti... DisGeNET Detail
NA DisGeNET Detail
IGF1R aberrations lead to intrauterine and postnatal growth failure, microcephaly, mental retardatio... DisGeNET Detail
Human deficiency in IGF1R is involved in growth failure, microcephaly, mental retardation and deafne... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Igf1r-deficient mice die at birth due to growth retardation and respiratory failure. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
A genetic association analysis of polymorphisms in 10 genes contributing to the IGF-I system (IGF1, ... DisGeNET Detail
NA DisGeNET Detail
The distal partial trisomy 15q included the insulin-like growth factor 1 receptor gene involved with... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In this study, MTB-IGFIR transgenic mice, which develop mammary tumors resulting from overexpression... DisGeNET Detail
Overexpression of IGF1R and FAK are closely associated with metastatic breast tumors. DisGeNET Detail
Inhibition of the type 1 insulin-like growth factor receptor (IGF1R) reduces the enhanced signaling,... DisGeNET Detail
NA DisGeNET Detail
Mounting evidence has shown that the insulin-like growth factor-1 receptor (IGF-1R) has critical rol... DisGeNET Detail
IGFs can inhibit DC-mediated anti-tumor immunity through suppressing maturation and function and the... DisGeNET Detail
We used ESCC cell lines and a mouse xenograft model to detect the function of IGF-1R in vitro and in... DisGeNET Detail
Activated cMET and IGF1R-driven PI3K signaling predicts poor survival in colorectal cancers independ... DisGeNET Detail
MiR-143 and MiR-145 regulate IGF1R to suppress cell proliferation in colorectal cancer. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
This study identifies NEDD4 as a putative oncogene in endometrial cancer that may augment activation... DisGeNET Detail
NA DisGeNET Detail
The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of ALL (mostly T cell ... DisGeNET Detail
The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of ALL (mostly T cell ... DisGeNET Detail
Association of IGF1R polymorphisms with the development of HBV-related hepatocellular carcinoma. DisGeNET Detail
The expression of pluripotency-related genes is associated with early tumor recurrence and is regula... DisGeNET Detail
A pleiotropic effect of the single clustered hepatic metastamiRs miR-96-5p and miR-182-5p on insulin... DisGeNET Detail
These findings indicate that the tumor-suppressor miR-1275 can control HCC tumor growth partially th... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
These results may improve the current understanding of the basic molecular mechanisms of TNBC metast... DisGeNET Detail
In the current study, the prognostic and predictive values of serum transforming growth factor-β1 (T... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Significantly less staining for IGF-1Rβ was observed in normal adjacent thyroid tissues of PTC patie... DisGeNET Detail
The distal partial trisomy 15q included the insulin-like growth factor 1 receptor gene involved with... DisGeNET Detail
Amplification of the insulin-like growth factor 1 receptor gene is a rare event in adrenocortical ad... DisGeNET Detail
The IGF-IR/IR ratios varied from <1 to 12 in the selected cell lines; similar pattern ranges were ob... DisGeNET Detail
NA DisGeNET Detail
In addition, IGF1R polymorphisms and abnormal microRNA expression did not correlate with IGF1R upreg... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Our data provide a strong rationale for targeting PR in combination with ER and IGF1R in patients wi... DisGeNET Detail
Our study provides proof-of-concept that inhibiting the IGF1R compensatory response to mTOR inhibiti... DisGeNET Detail
In both the primary cancers and the metastases, Claudin-4 was most frequently expressed, followed by... DisGeNET Detail
Aberrant allele-switch imprinting of a novel IGF1R intragenic antisense non-coding RNA in breast can... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
This study identifies NEDD4 as a putative oncogene in endometrial cancer that may augment activation... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Relevance of insulin-like growth factor 1 receptor gene expression as a prognostic factor in non-sma... DisGeNET Detail
Expression of insulin-like growth factor 1 receptor (IGF-1R) predicts poor responses to epidermal gr... DisGeNET Detail

Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386584794 dbSNP
Genome
hg19
Position
chr15:99,191,768-99,507,759
Variant Type
snv
Genome browser