Annotation Detail

Information
Associated Genes
IGF1R
Associated Variants
IGF1R MUTATION
IGF1R MUTATION
Associated Disease
Hypertensive disease
Source Database
DisGeNET
Description
These data suggest that Rg5 plays a novel role as an IGF-1R agonist, promoting therapeutic angiogenesis and improving hypertension without adverse effects in the vasculature.
Pubmed
25391655
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
10
Original source reporting the Gene Disease association
BeFree,GAD,RGD
DisGENET score for the Gene Disease association
0.087915421552047
Drugs