congenital diaphragmatic hernia
Information
- Disease name
- congenital diaphragmatic hernia
- Disease ID
- DOID:3827
- Description
- "A diaphragm disease characterized by the lack of development of all or part of the diaphragm, which results in an abnormal opening that allows the stomach and intestines to move into the chest cavity and crowd the heart and lungs." [url:http\://en.wikipedia.org/wiki/Congenital_diaphragmatic_hernia, url:http\://ghr.nlm.nih.gov/condition/congenital-diaphragmatic-hernia]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
| Genes | Mutation | Description | Source | Links |
|---|
| NCT ID | Status | Phase | Summary | Start date | Completion date |
|---|---|---|---|---|---|
| NCT05839340 | Active, not recruiting | N/A | Neurally Adjusted Ventilatory Assist for Neonates With Congenital Diaphragmatic Hernias | May 26, 2023 | June 1, 2024 |
| NCT02951130 | Active, not recruiting | Phase 2 | Milrinone in Congenital Diaphragmatic Hernia | August 22, 2017 | March 31, 2025 |
| NCT04484441 | Active, not recruiting | Maternal-fetal Immune Responses to Fetal Surgery | March 24, 2022 | December 2024 | |
| NCT01467245 | Completed | N/A | Open or Keyhole Surgery Through the Chest for Newborn Babies: Effect on Blood Gases | August 2009 | August 2013 |
| NCT03787160 | Completed | N/A | Microbiome and Volatile Organic Compounds in Patients With CDH | March 22, 2018 | October 1, 2019 |
| NCT02033772 | Completed | Prospective Data Collection of Patients < 6 Months of Age Undergoing Thoracoscopic Surgery | August 2013 | October 6, 2017 | |
| NCT02453750 | Completed | N/A | Airway Inflammation in Congenital Diaphragmatic Hernia Patients | February 2012 | October 2013 |
| NCT00881660 | Completed | N/A | Fetal Endotracheal Occlusion (FETO) in Severe and Extremely Severe Congenital Diaphragmatic Hernia | February 21, 2012 | April 11, 2023 |
| NCT03242044 | Completed | N/A | Resuscitation of Infants With Congenital Diaphragmatic Hernia With an Intact Umbilical Cord | January 12, 2018 | October 21, 2020 |
| NCT03314233 | Completed | N/A | Delayed Cord Clamping for Congenital Diaphragmatic Hernia | October 12, 2017 | October 9, 2018 |
| NCT03666767 | Completed | Management and Outcomes of Congenital Anomalies in Low-, Middle- and High-Income Countries | October 1, 2018 | February 9, 2020 | |
| NCT00763737 | Completed | N/A | Fetal Surgery for Moderate Left Sided Congenital Diaphragmatic Hernia. | August 2010 | March 2020 |
| NCT02875860 | Completed | Phase 2 | 'TOTAL' (Tracheal Occlusion To Accelerate Lung Growth) Trial | January 2017 | October 2019 |
| NCT01155830 | Completed | Inflammatory Cytokine Quantification in Infants | June 2010 | June 2013 | |
| NCT01243229 | Completed | Genetic Analysis of Congenital Diaphragmatic Disorders | October 2010 | June 1, 2021 | |
| NCT05612503 | Completed | N/A | Virtual Reality and Congenital Diaphragmatic Hernia | January 10, 2021 | April 15, 2022 |
| NCT05962346 | Enrolling by invitation | N/A | Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia | May 2025 | July 2043 |
| NCT05666986 | Not yet recruiting | Engagement in Physical Activities and Sports in Adolescents With Diaphragmatic Hernia | March 2023 | March 2024 | |
| NCT05213676 | Not yet recruiting | Phase 4 | Inhaled Nitric Oxide (iNO) for Congenital Diaphragmatic Hernia (CDH) - The "NoNO Trial" - a Multi-center, De-implementation, Stepped-wedge, Cluster-randomized Trial Within an Established Collaborative | January 1, 2025 | December 31, 2030 |
| NCT05421676 | Not yet recruiting | N/A | Fetal Endoscopic Tracheal Occlusion for CDH (CDH) | October 2024 | December 2027 |
| NCT06179472 | Not yet recruiting | N/A | Fetoscopic Endoluminal Tracheal Occlusion for Severe Left and Right Congenital Diaphragmatic Hernia | January 15, 2025 | January 1, 2035 |
| NCT06281717 | Not yet recruiting | N/A | Fetal Endotracheal Occlusion (FETO) in Fetuses With Severe Congenital Diaphragmatic Hernia | September 1, 2024 | February 28, 2031 |
| NCT06408376 | Recruiting | N/A | Physiological Umbilical Cord Clamping in Patients With Congenital Diaphragmatic Hernia. Clinical Trial | June 14, 2022 | December 31, 2026 |
| NCT00950118 | Recruiting | Diaphragmatic Hernia Research & Exploration, Advancing Molecular Science | June 2005 | November 2025 | |
| NCT02549820 | Recruiting | N/A | Fetoscopic Endoluminal Tracheal Occlusion in Severe Left Congenital Diaphragmatic Hernia | July 2015 | December 2025 |
| NCT02596802 | Recruiting | N/A | Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Congenital Diaphragm Hernia | December 1, 2015 | December 1, 2025 |
| NCT02710968 | Recruiting | N/A | Fetoscopic Endoluminal Tracheal Occlusion (FETO) for Severe Left Diaphragmatic Hernia (CDH) | August 2015 | March 2025 |
| NCT02986087 | Recruiting | N/A | Feto-Endoscopic Tracheal Occlusion (FETO) for Left Congenital Diaphragmatic Hernia | November 2016 | December 2026 |
| NCT03138863 | Recruiting | N/A | Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia (FETO) | May 1, 2024 | September 1, 2028 |
| NCT03526588 | Recruiting | Phase 1 | Umbilical Cord Blood Mononuclear Cells for Hypoxic Neurologic Injury in Infants With Congenital Diaphragmatic Hernia (CDH) | August 1, 2018 | November 1, 2027 |
| NCT03674372 | Recruiting | N/A | Fetoscopic Endoluminal Tracheal Occlusion | November 16, 2018 | March 2030 |
| NCT03750266 | Recruiting | 3D Animation and Models to Aid Management of Fetal CDH | October 4, 2017 | June 30, 2025 | |
| NCT03980717 | Recruiting | N/A | Fetal Endotracheal Occlusion (FETO) in the Resolution of Pulmonary Hypertension in Fetuses With Severe CDH | August 9, 2019 | December 2030 |
| NCT04052828 | Recruiting | N/A | Fetal Endoscopic Tracheal Occlusion (FETO) Trial for Congenital Diaphragmatic Hernia (CDH) | April 5, 2021 | June 2028 |
| NCT04114578 | Recruiting | Exploratory Observational Prospective Study in Neonatal and Pediatric Congenital Diaphragmatic Hernia | October 1, 2019 | July 30, 2024 | |
| NCT04429750 | Recruiting | N/A | Intact Cord Resuscitation in CDH | October 8, 2020 | October 2025 |
| NCT04583644 | Recruiting | N/A | Pilot Trial of Fetoscopic Endoluminal Tracheal Occlusion (FETO) in Severe Left Congenital Diaphragmatic Hernia (CDH) | October 2, 2020 | April 2028 |
| NCT04774848 | Recruiting | N/A | High Frequency Oscillatory Ventilation Versus High Frequency Jet Ventilation for Congenital Diaphragmatic Hernia | December 30, 2020 | February 28, 2025 |
| NCT04931212 | Recruiting | N/A | Fetoscopic Endoluminal Tracheal Occlusion (FETO) With Smart-TO | August 4, 2021 | October 2024 |
| NCT05051254 | Recruiting | N/A | Respiratory Muscles and Work of Breathing in Children | January 19, 2022 | January 2028 |
| NCT05100693 | Recruiting | N/A | Smart Removal for Congenital Diaphragmatic Hernia | September 8, 2021 | November 1, 2026 |
| NCT05201144 | Recruiting | Phase 2 | A Trial of Phosphodiesterase-5 Inhibitor in Neonatal Congenital Diaphragmatic Hernia (TOP-CDH) | September 15, 2022 | September 2025 |
| NCT05450653 | Recruiting | N/A | Trial of FETO for Severe Congenital Diaphragmatic Hernia | September 18, 2022 | November 2027 |
| NCT05461222 | Recruiting | N/A | Fetal Endoscopic Tracheal Occlusion (FETO) for Severe Congenital Diaphragmatic Hernia | April 17, 2023 | August 31, 2027 |
| NCT05985564 | Recruiting | Retrospective Comparative Study on Imaging Between the Bochdalek Hernia and Congenital Diaphragmatic Eventration | March 18, 2022 | December 31, 2023 | |
| NCT06050525 | Recruiting | Incidence of Acute Kidney Injury and Risk Factors in Newborns With Congenital Diaphragmatic Hernia | February 1, 2023 | October 31, 2024 | |
| NCT00257946 | Terminated | Phase 3 | Type of Material in Repair of Congenital Diaphragmatic Hernia | December 2005 | August 2007 |
| NCT04140669 | Terminated | Automated Myocardial Performance Index Using Samsung HERA W10 | September 16, 2019 | July 7, 2020 | |
| NCT04396028 | Unknown status | Measurement of Lung Area at Chest Radiography to Define the Prognosis in Newborns With CDH | July 9, 2020 | December 31, 2021 | |
| NCT04507295 | Unknown status | N/A | Cerebral Blood Flow in Neonates During Thoracoscopic Surgeries | August 8, 2020 | November 15, 2020 |
| NCT01302977 | Unknown status | Phase 2 | Fetal Tracheal Occlusion in Severe Diaphragmatic Hernia: a Randomized Trial | May 2008 | December 2011 |
| NCT04609163 | Unknown status | Machine and Deep Learning for Congenital Diaphragmatic Hernia (CLANNISH) | December 1, 2021 | December 1, 2022 | |
| NCT03179371 | Unknown status | Proteomic Profiling for Congenital Diaphragmatic Hernia | May 18, 2017 | November 2019 | |
| NCT01098929 | Unknown status | Gene Mutations and Rescue in Human Congenital Diaphragmatic Hernia | July 2002 | July 2017 | |
| NCT03788122 | Unknown status | N/A | Fetal Surgery Interview Study: Parental Perceptions of Fetal Surgery | July 1, 2018 | March 2020 |
| NCT02849054 | Unknown status | N/A | CDH - Optimisation of Neonatal Ventilation | June 2016 | December 2021 |
| NCT01731509 | Unknown status | Phase 2 | Early FETO for Severe Congenital Diaphragmatic Hernia | June 2014 | December 2016 |
| NCT03094039 | Withdrawn | N/A | Initiation of Resuscitation While Attached to the Cord With Congenital Diaphragmatic Hernia | April 27, 2017 | August 31, 2019 |
| NCT04186039 | Withdrawn | N/A | Functional Evaluation of the Fetal Lung by Functional Magnetic Resonance Imaging - Blood Oxygenation Level Dependent (MRI-BOLD), in Congenital Diaphragmatic and Parietal Malformations | May 2020 | May 2022 |
- Disase is a (Disease Ontology)
- DOID:10481
- Cross Reference ID (Disease Ontology)
- GARD:1481
- Cross Reference ID (Disease Ontology)
- ICD10CM:K44
- Cross Reference ID (Disease Ontology)
- MESH:D006548
- Cross Reference ID (Disease Ontology)
- MIM:142340
- Cross Reference ID (Disease Ontology)
- MIM:222400
- Cross Reference ID (Disease Ontology)
- MIM:610187
- Cross Reference ID (Disease Ontology)
- NCI:C34687
- Cross Reference ID (Disease Ontology)
- ORDO:2140
- Cross Reference ID (Disease Ontology)
- SNOMEDCT_US_2023_03_01:155748004
- Cross Reference ID (Disease Ontology)
- UMLS_CUI:C0019284
- Exact Synonym (Disease Ontology)
- Diaphragmatic Hernia
- HPO alt_id (Human Phenotype Ontology)
- HP:0006604
- HPO Human Phenotype ID (Human Phenotype Ontology)
- HP:0000776
- OrphaNumber from OrphaNet (Orphanet)
- 2140
- ICD10 preferred id (Insert disease from ICD10)
- D0014080
- ICD10 class code (Insert disease from ICD10)
- Q79.0