Annotation Detail

Information
Associated Genes
IGF1R
Associated Variants
IGF1R MUTATION
IGF1R MUTATION
Associated Disease
Triple Negative Breast Neoplasms
Source Database
DisGeNET
Description
These results may improve the current understanding of the basic molecular mechanisms of TNBC metastasis and provide a strong rationale for co-targeting of IGF1R and FAK as therapy for mesenchymal TNBCs.
Pubmed
25749031
Section of the abstract supporting the evidence
ALL_TEXT_3/3
Number of the section of the abstract supporting the evidence
3
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.000542883744160607
Drugs