Annotation Detail
Information
- Associated Genes
- IGF1R
- Associated Variants
-
IGF1R MUTATION
IGF1R MUTATION - Associated Disease
- B-Cell Lymphomas
- Source Database
- DisGeNET
- Description
- The absence of Esr2 resulted in increased apoptosis, decreased B-cell lymphoma 2 (BCL2), and IGF-1 receptor (IGF1R) expression, and decreased levels of active MAPKs (ERK1/2) and protein kinase B (AKT).
- Pubmed
- 25885794
- Section of the abstract supporting the evidence
- ALL_TEXT_2/3
- Number of the section of the abstract supporting the evidence
- 2
- Number of the sentence supporting the evidence
- 4
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000542883744160607
Drugs