Annotation Detail
Information
- Associated Genes
- IGF1R
- Associated Variants
-
IGF1R MUTATION
IGF1R MUTATION - Associated Disease
- Phyllodes Tumor
- Source Database
- DisGeNET
- Description
- Taken together, this study defines the genomic landscape underlying phyllodes tumor development, suggests potential molecular correlates to histologic grade, expands the spectrum of human tumors with frequent recurrent MED12 mutations, and identifies IGF1R and EGFR as potential therapeutic targets in malignant cases.
- Pubmed
- 25593300
- Section of the abstract supporting the evidence
- UNLABELLED
- Number of the section of the abstract supporting the evidence
- 1
- Number of the sentence supporting the evidence
- 6
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.000271441872080303
Drugs