Annotation Detail

Information
Associated Genes
IGF1R
Associated Variants
IGF1R MUTATION
IGF1R MUTATION
Associated Disease
endometrial carcinoma
Source Database
DisGeNET
Description
This study identifies NEDD4 as a putative oncogene in endometrial cancer that may augment activation of the IGF-1R/PI3K/Akt signaling pathway.
Pubmed
26193427
Section of the abstract supporting the evidence
CONCLUSIONS
Number of the section of the abstract supporting the evidence
4
Number of the sentence supporting the evidence
12
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00135720936040152
Drugs