Annotation Detail

Information
Associated Genes
IGF1R
Associated Variants
IGF1R MUTATION
IGF1R MUTATION
Associated Disease
Precursor T-Cell Lymphoblastic Leukemia-Lymphoma
Source Database
DisGeNET
Description
The depletion of IGF-IR expression in BCR/ABL(+) cells led to the development of ALL (mostly T cell ALL) but not CML.
Pubmed
25648584
Section of the abstract supporting the evidence
METHODS AND RESULTS
Number of the section of the abstract supporting the evidence
2
Number of the sentence supporting the evidence
9
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00081432561624091
Drugs