Annotation Detail

Information
Associated Genes
IGF1R
Associated Variants
IGF1R MUTATION
IGF1R MUTATION
Associated Disease
leukemia
Source Database
DisGeNET
Description
Upregulation of IGF1R by mutant RAS in leukemia and potentiation of RAS signaling inhibitors by small-molecule inhibition of IGF1R.
Pubmed
25186968
Section of the abstract supporting the evidence
TITLE
Number of the section of the abstract supporting the evidence
0
Number of the sentence supporting the evidence
0
Original source reporting the Gene Disease association
BeFree
DisGENET score for the Gene Disease association
0.00108576748832121
Drugs