Annotation Detail
Information
- Associated Genes
- IGF1R
- Associated Variants
-
IGF1R MUTATION
IGF1R MUTATION - Associated Disease
- Ewings sarcoma
- Source Database
- DisGeNET
- Description
- We showed that trabectedin may not only inhibit but also enhance the binding of EWS-FLI1 to certain target genes, leading to upregulation of IGF1R.
- Pubmed
- 25609059
- Section of the abstract supporting the evidence
- CONCLUSIONS
- Number of the section of the abstract supporting the evidence
- 4
- Number of the sentence supporting the evidence
- 9
- Original source reporting the Gene Disease association
- BeFree
- DisGENET score for the Gene Disease association
- 0.00108576748832121
Drugs