respiratory failure

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Information
Disease name
respiratory failure
Disease ID
DOID:11162
Description
"A lung disease characterized by inadequate gas exchange by the respiratory system." [url:http\://en.wikipedia.org/wiki/Respiratory_failure]
Disease area statistics
Chromosome band
Gene symbol Chromosome Start Stop The number of variant
TUFM 16 28,842,411 28,846,348 8
COQ4 9 128,322,839 128,334,072 8
BOLA3 2 74,135,400 74,147,912 8
NDUFB11 X 47,142,071 47,145,466 4
MECP2 X 154,021,573 154,097,717 4
NDUFS4 5 53,560,639 53,683,338 4
Annotation
Genes Mutation Description Source Links
NCT ID Status Phase Summary Start date Completion date
NCT04669444 Active, not recruiting N/A Biomarkers, Genomics, Physiology in Critically Ill and ECMO Patients April 14, 2020 March 1, 2023
NCT02819141 Active, not recruiting Phase 2/Phase 3 Self-management of Sedative Therapy by Ventilated Patients November 2016 December 2024
NCT01705119 Active, not recruiting N/A The Effects of Vertical Position on Gas Exchange in Patients With Respiratory Failure October 1, 2012 December 2024
NCT04558476 Active, not recruiting Phase 2 Efficacy of CONvalescent Plasma in Patients With COVID-19 Treated With Mechanical Ventilation September 11, 2020 April 2023
NCT03546699 Active, not recruiting Hospital-wide Incidence, Clinical Characteristics and Outcomes of ARDS October 24, 2018 October 15, 2023
NCT06374589 Active, not recruiting N/A Closed-Loop O2 Use During High Flow Oxygen Treatment Of Critical Care Adult Patients (CLOUDHFOT) March 21, 2024 December 30, 2024
NCT04360538 Active, not recruiting Long Term Outcomes of Patients With COVID-19 April 8, 2020 December 1, 2024
NCT05698602 Active, not recruiting N/A Safety and Performance of NivolisMonitor and NivolisAnton for Monitoring Patients on Ventilatory Assistance at Home April 24, 2023 December 31, 2025
NCT03471247 Active, not recruiting N/A CYCLE: A Randomized Clinical Trial of Early In-bed Cycling for Mechanically Ventilated Patients October 15, 2018 August 2024
NCT03472768 Active, not recruiting The Impact of Age-dependent Haptoglobin Deficiency on Plasma Free Hemoglobin Levels During Extracorporeal Membrane Oxygenation Support September 25, 2018 September 2024
NCT00314080 Completed Treatment of Survivors After Botulism Outbreak March 2006 April 2006
NCT00315263 Completed Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology April 2006 July 2011
NCT00325611 Completed N/A Multidisciplinary Inpatient Palliative Care Intervention April 2002 July 2004
NCT00347321 Completed Phase 3 Early Percutaneous Tracheostomy for Cardiac Surgery (ETOC) July 2006 June 2009
NCT00355732 Completed Phase 4 Chronic Obstructive Pulmonary Disease and Weaning From Mechanical Ventilation in Difficult to Wean Patients
NCT06113432 Completed N/A CPAP Therapy Through a Helmet or a Full Face Mask in Patients With Acute Hypoxemic Respiratory Failure: Cross-over Study September 19, 2023 May 30, 2024
NCT00400881 Completed N/A Comparison Between Two Methods of Spontaneous Breathing Trial (SBT) January 2007 January 2011
NCT00405002 Completed A Validation Study of a New System for Measuring the End Expiratory Lung Volume During Mechanical Ventilation November 2006 July 2008
NCT00419458 Completed Phase 1 Inspiratory Muscle Training in Ventilator Dependent Patients February 2004 July 2009
NCT00448565 Completed Prediction of Extubation Success by the Patient January 2007
NCT06083272 Completed VitalThings Guardian Contactless Monitoring November 15, 2023 November 28, 2023
NCT00539708 Completed N/A Non-Invasive Ventilation After Extubation in Hypercapnic Patients May 2005 April 2008
NCT00549809 Completed Phase 3 Comparison Between IMV and SIMV/PS for Ventilatory Support of Children: a Randomized Clinical Trial October 2005 June 2007
NCT00553046 Completed Last 3 Months of Life in Home Ventilated Patients January 2005 April 2007
NCT00603174 Completed N/A Use of Neurally Adjusted Ventilatory Assist in Infants Respiratory Failure January 2008 September 2009
NCT00647361 Completed Phase 1 Mechanical Ventilation Controlled by the Electrical Activity of the Patient's Diaphragm - Effects on Cardiac Performance March 2008 June 2010
NCT06079034 Completed Impact of Cannulation Strategy on Neurologic Injury in Infants With Respiratory Failure October 18, 2023 December 12, 2023
NCT00678912 Completed Phase 3 Weaning Children From Mechanical Ventilation:Computer-driven System Versus Usual Care September 2007 July 2009
NCT06008470 Completed Investigation of Respiratory Muscle Strength, Exercise Capacity, Physical Activity and Sleep Quality Level in Individuals With Covid-19 Infection September 1, 2023 February 25, 2024
NCT00708149 Completed Phase 4 Comparison of the Efficacy for Stress Ulcer Prophylaxis Between the Patients Received Lansoprazole OD and Control Group Weaning From Mechanical Ventilator in Respiratory Care Center: a Randomized Control Trial June 2009 February 2012
NCT00732537 Completed Phase 4 Inhaled Nitric Oxide by Oxygen Hood in Neonates March 1999 June 2005
NCT00810459 Completed N/A Trilogy Comparison Study - Pediatrics March 10, 2008 January 26, 2009
NCT00810498 Completed N/A Trilogy Comparison Study - Adults March 12, 2008 February 5, 2009
NCT06004206 Completed N/A Patient-ventilator Interaction During NIV With Helmet: a Comparison Between PSV and the New NIV NPS Software October 1, 2020 June 15, 2023
NCT00817297 Completed N/A Cross-over Comparison of the V60 System to Other Bi-Level Noninvasive Ventilators January 17, 2009 April 7, 2009
NCT00817804 Completed N/A Cross-over Comparison of the V60 System to Other Bi-Level Noninvasive Ventilators January 2009 March 2009
NCT05948332 Completed Definition and Management of Right Ventricular Injury in Adult Patients Receiving Extracorporeal Membrane Oxygenation September 1, 2023 January 1, 2024
NCT05846945 Completed N/A Threshold Inspiratory Trainer Versus Trigger Sensitivity Adjustment on Weaning From Mechanical Ventilation August 12, 2021 July 10, 2022
NCT00885898 Completed N/A Out-of-Hospital Non-Invasive Ventilation for Patients With Acute Respiratory Failure March 2005 April 2009
NCT05820347 Completed N/A Muscle Pressure Estimation With Artificial Intelligence During Mechanical Ventilation August 26, 2022 July 18, 2023
NCT01020773 Completed N/A Extubation With or Without Spontaneous Breathing Trial June 2006 October 2007
NCT01024088 Completed Prospective Study on Swallowing/Breathing Interactions in Severe Guillain Barre Syndrome. March 2008 July 2012
NCT01047852 Completed N/A Noninvasive Ventilation After Extubation in Hypercapnic Patients January 2010 August 2011
NCT01054183 Completed N/A The Use of the GlideScope Ranger in Pediatric Critical Care Transport July 2010 December 2011
NCT01056952 Completed N/A Physiologic Effects of High Flow Nasal Therapy in Patients With Acute Hypoxemic Respiratory Failure (OPTIFLOW) January 2010 January 2012
NCT01065428 Completed Extubation Readiness and Neuroventilatory Efficiency After Acute Respiratory Failure December 2008 July 2010
NCT05817968 Completed N/A Solid State vs. Balloon Esophageal Catheter for Estimation of Pleural Pressure October 20, 2023 March 21, 2024
NCT01108575 Completed Phase 1/Phase 2 Effect of Inspiratory Muscle Training on Duration of Mechanical Ventilation Support May 2010 January 2013
NCT01111578 Completed Evaluation of a New Enteral Feeding Tube for the Measurement of Esophageal and Gastric Pressure November 2009 September 2010
NCT01136109 Completed A Study to Evaluate the Effect of Mechanical Ventilation on the Inferior Vena Cava Collapsibility Index October 2009 February 2013
NCT05805579 Completed Diaphragmatic Echography in COVID-19 Pneumonia February 1, 2021 June 20, 2021
NCT01160978 Completed Phase 2/Phase 3 Donor Simvastatin Treatment in Organ Transplantation June 1, 2010 August 1, 2016
NCT05708287 Completed N/A The Physiologic Effect of the Flow Generated by High Flow Nasal Cannula in Mild Respiratory Failure August 1, 2020 December 31, 2020
NCT01204281 Completed Phase 4 Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients September 2010 September 2012
NCT01238757 Completed N/A Patient-ventilator Asynchrony During Mechanical Non-Invasive Assisted-ventilation in Pediatric Patients (NavPed-NI) June 2010 September 2011
NCT01239433 Completed Pathophysiologic Changes in the Respiratory System During Therapeutic Interventions May 2011 May 2016
NCT01249794 Completed N/A Non Invasive Ventilation After Cardiac Surgery September 2010 December 2013
NCT01276652 Completed N/A Sleep and Circadian Rhythms in Mechanically Ventilated Patients November 2001 December 2008
NCT05617404 Completed Blunt Thoracic Trauma: Definition of a Standard Operating Procedure February 1, 2020 March 1, 2021
NCT01284140 Completed N/A Improving the Sleep and Circadian Rhythms of Mechanically Ventilated Patients January 2011 December 2016
NCT05595707 Completed N/A Expert-Guided Early Tracheostomy Pathway January 2, 2018 September 30, 2022
NCT01286610 Completed N/A Applicability and Safety of Vibration Therapy in Intensive Care Unit (ICU) Patients February 2011 May 2012
NCT01306201 Completed Novel Non-Invasive Monitoring Parameter in a Hospital Setting February 2011 March 2012
NCT05591209 Completed Pattern of Admission and Outcome of Patients Admitted to the Intensive Care April 1, 2022 August 30, 2022
NCT05589233 Completed COVID-19 Vaccination AZV 2021-2023 January 1, 2021 November 30, 2023
NCT01335932 Completed Phase 2 Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure March 10, 2011 October 28, 2016
NCT01337271 Completed N/A Performance of Neurally Adjusted Ventilatory Assist (NAVA) During Spontaneous Breathing Trial May 2011 September 2013
NCT05580185 Completed Multicenter, Multinational, Follow-Up Clinical Trial of the Performance of RESPINOR DXT to Identify Patients at Increased Risk of Weaning Failure December 8, 2022 July 30, 2023
NCT01370278 Completed N/A Clearance Of Mucus In Stents (COMIS) June 16, 2011 August 23, 2023
NCT01372995 Completed Phase 2 Vitamin D in Ventilated ICU Patients July 2011 April 2014
NCT05563779 Completed N/A Mode Of Ventilation During Critical IllnEss Pilot Trial November 1, 2022 August 28, 2023
NCT01410149 Completed N/A Sleep Quality in Mechanically Ventilated Patients April 2007 December 2011
NCT01472302 Completed Phase 4 Closed Loop Ventilation Strategy in Intensive Care Unit (ICU) Patients April 2012 January 2014
NCT01504373 Completed Regional Distribution Differences Between Neurally Adjusted Ventilatory Assist and Pressure Support Ventilation May 2011 April 2020
NCT01519388 Completed N/A Evaluation of the Impact on Swallowing of Non Invasive Ventilation February 2012 May 2013
NCT01565941 Completed Phase 3 Heart And Lung Failure - Pediatric INsulin Titration Trial April 2012 February 2018
NCT01575353 Completed N/A Nasal High-flow Versus Venturi Mask Oxygen Therapy in the Post-extubation Period December 2010 November 2011
NCT01577667 Completed Phase 3 Intellivent Versus Conventional Ventilation February 2011 June 2012
NCT01602640 Completed N/A Comparison of Morphine and Fentanyl/Midazolam in Intensive Care Unit January 2009 March 2012
NCT01610960 Completed N/A Comparison of Three Noninvasive Ventilation Modes: a Physiological Study in Healthy Volunteers April 2012 August 2012
NCT01616901 Completed N/A Wean Obese Study : Determination of the Optimal Spontaneous Breathing Trial for Obese Patient April 2012 April 2013
NCT05451121 Completed N/A Effect of Sedation Strategy on Duration Mechanical Ventilation in Patient After Cardiac Surgery July 1, 2017 July 1, 2019
NCT05403320 Completed N/A Cuff Pressure Control and Evacuation of Subglottic Secretions To Prevent Pneumonia June 6, 2022 April 9, 2024
NCT01628523 Completed Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study July 2012 March 2014
NCT01644162 Completed N/A Ventilator Monitoring in Early Exacerbation Detection July 2012 January 2014
NCT01659268 Completed N/A Performance of Baccalaureate Nursing Students in Insertion of Laryngeal Mask: a Trial in Mannequins September 2012 December 2012
NCT01663480 Completed To Identify the Proportionality of Respiratory Work Under Different NAVA Level March 2011 December 2013
NCT01666834 Completed Cross-section Survey of Mechanical Ventilation and Acute Respiratory Distress Syndrome in China July 2012 May 2013
NCT01683526 Completed N/A Safety and Efficacy of Endotracheal Intubation Using Glidescope Video-Laryngoscope August 2012 April 2013
NCT01692847 Completed Examination of the Impact of Better Surveillance and Communication of Patient Deterioration on Patient Related Outcomes October 2012 February 2016
NCT05322447 Completed Phase 4 High-dose L-Carnitine and Diaphragmatic Function Assessed by Ultrasonography in Patients With Respiratory Failure. April 15, 2022 October 1, 2022
NCT05274490 Completed COPD Prognosis in Covid Patients June 1, 2021 January 1, 2022
NCT01757093 Completed N/A Evaluation of Oxygen Consumption and Energy Expenditure During Spontaneous Breathing Trial. June 2012 September 2013
NCT05254691 Completed N/A WOB and Paediatric Mechanical Ventilation November 29, 2017 February 5, 2019
NCT01777035 Completed N/A Early Mobilization in the ICU July 19, 2011 January 14, 2022
NCT05159401 Completed N/A The Use of Vibrational Methods of Influencing the Lungs to Restore Their Functional State January 18, 2022 May 14, 2023
NCT05132933 Completed N/A Gas Exchange Derangement Physiopathology in Critically Ill Patients With COVID-19 October 1, 2021 December 30, 2022
NCT05130541 Completed N/A Proning Early in Awake COVID-19 Hypoxic Respiratory Failure (PREACHR) Study June 1, 2020 May 1, 2021
NCT05129930 Completed Fluid Overload and Pulmonary Function December 1, 2020 May 1, 2021
NCT01819090 Completed N/A Optimizing Communication During Ventilation November 2013 March 2015
NCT01838343 Completed N/A Efficacy of Ultrasound to Guide Management During a Rapid Response Event March 2013 March 2014
NCT05045885 Completed Safety and Feasibility of Percutaneous Dilatational Tracheostomy in Patients With Severe COVID-19 Supported by ECMO March 1, 2020 December 1, 2020
NCT01870765 Completed N/A Safety Study of Non-invasive Ventilation Versus High-flow Oxygen in Patients With Hypoxemic Respiratory Failure Undergoing Fiberoptic Bronchoscopy. July 2013 February 2014
NCT01878643 Completed Early Phase 1 Reduction of Bacterial Resistance With Inhaled Antibiotics in the Intensive Care Unit December 2001 December 2002
NCT01885442 Completed N/A TryCYCLE: A Pilot Study of Early In-bed Leg Cycle Ergometry in Mechanically Ventilated Patients September 2013 January 2015
NCT05032365 Completed N/A Closed-loop FiO2 Controller During High Flow Oxygen Treatment In Pediatric Patients (COFICOHFOT) September 1, 2021 February 1, 2022
NCT01892969 Completed Coagulation and Fibrinolysis in Pediatric Insulin Titration Trial (CAF-PINT) October 2012 September 2016
NCT04987398 Completed Ventilation Weaning Strategies and Correlation to Outcomes in Tracheostomized Patients in the Lausanne ICU June 10, 2021 May 15, 2022
NCT01900990 Completed N/A Noninvasive Positive Pressure Ventilation for Difficult Weaning in Tracheotomy Patients July 2009 October 2011
NCT01902446 Completed Prehospital Ventilator-Associated Pneumonia Prevention Trial July 2013 October 2014
NCT01931228 Completed N/A Mechanical Insufflation-Exsufflation in Preventing Post Extubation Respiratory Failure in Patient With Critical Care Neuromyopathy May 3, 2012 May 2016
NCT01941524 Completed Phase 4 Brain Oxygenation and Function of Preterm Newborns During Administration of Two Different Surfactant Preparations March 3, 2013 June 20, 2015
NCT01945944 Completed Phase 1/Phase 2 Nebulized Hypertonic Saline for Mechanically Ventilated Children October 2013 May 2014
NCT01949402 Completed A New Way of Looking at Your Lungs February 2014 July 31, 2016
NCT01973829 Completed N/A The Checklist for Early Recognition and Treatment of Acute Illness (CERTAIN) November 2013 March 2018
NCT01973894 Completed Midazolam Whole Body Physiologically Based Pharmacokinetic Model January 2013 May 2014
NCT01985685 Completed Phase 2 The Effect of Thiamine vs. Placebo on VO2 in Critical Illness October 2013 December 2016
NCT01994928 Completed N/A Preoxygenation in the Intensive Care Unit Using a Nose-mouth Mask Versus High-flow Nasal Cannula Oxygen. November 2013 November 2014
NCT02003053 Completed N/A A Randomized, Controlled Trial of Inspiratory Muscle Training (IMT)in the ICU and CCU April 2013 December 2015
NCT04977011 Completed N/A Effectiveness of Music Intervention on Anxiety and Physiological Responses in Critical Ill Patient January 2, 2019 July 30, 2019
NCT02032030 Completed Systematic Assessment and Targeted Improvement of Services Following Yearlong Surgical Outcomes Surveys July 2012 October 21, 2020
NCT04925167 Completed N/A Safety and Efficacy of Argatroban Applicated in Anticoagulation of V-V ECMO July 6, 2021 December 31, 2023
NCT02038491 Completed RICALOR Italian Registry for Complications During Regional Anesthesia May 2009 March 2013
NCT02039297 Completed N/A Patient Centered Cloud-based Electronic System: Ambient Warning and Response Evaluation (ProCCESs AWARE) March 2013 June 2017
NCT04818866 Completed International Study of Inflammation in COVID-19 February 1, 2020 December 1, 2022
NCT02051816 Completed N/A Facilitating EndotracheaL Intubation by Laryngoscopy Technique and Apneic Oxygenation Within the Intensive Care Unit: The FELLOW Study February 2014 February 2015
NCT04798794 Completed PCO2 ELSO (Extracorporeal Life Support Organization) January 1, 2015 December 11, 2020
NCT04787666 Completed N/A Comparison of Non-invasive Methods of Lung Ventilation in Patients With Respiratory Failure After Cardiac Surgery March 3, 2021 June 23, 2023
NCT02105298 Completed Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study) September 2013 March 2014
NCT02154542 Completed N/A Study to Improve Treatments and Follow-up of Children Who Need Respiratory Support October 2013 September 2014
NCT02159196 Completed N/A Effectiveness of Routine Nebulization of Mucolytics and Bronchodilators During Mechanical Ventilation July 2014 June 2017
NCT02163382 Completed N/A Impact of NAVA (Neurally Adjusted Ventilatory Assist) on Ventilatory Demand During Pediatric Non-Invasive Ventilation November 2011 May 2013
NCT02178982 Completed Standard Treatment Compliance of Participants, Effectiveness and Prognosis in Acute Respiratory Distress Syndrome May 2014 June 2015
NCT02180919 Completed Phase 1 Implementation of Telemonitoring in Chronic Heart or Lung Failure June 2010 August 2012
NCT02186197 Completed The Impact of Fellow-performed Cardiopulmonary Ultrasound Exams July 2014 July 2015
NCT02203019 Completed Phase 4 Study of Sedative Medications in Patients With Severe Infection and Respiratory Failure August 2014 September 22, 2016
NCT04764799 Completed HEAVEN Criteria: Prediction of Difficult Airway for In- Hospital Emergency Airway Management December 1, 2021 December 31, 2023
NCT04736212 Completed Assessment of Breathing Using an Under-bed Weighing Scale March 24, 2021 April 1, 2022
NCT02223988 Completed N/A Occurrence of Ventilator Associated Pneumonia in Italian ICU Using Cuffed Tracheostomy Tubes With Subglottic Secretion Drainage July 2014 July 2016
NCT02227810 Completed N/A Electrical Stimulation in Patients With Prolonged Mechanical Ventilation August 2012 July 2014
NCT04696406 Completed Multicenter, Multinational, Clinical Trial of the Performance of RESPINOR DXT to Identify Patients at Increased Risk of Weaning Failure May 11, 2021 April 30, 2022
NCT02242162 Completed Establishment of a Non-invasive and Indirect Measure of Volitional Pimax May 2009 January 2016
NCT02247700 Completed Observational Cohort Study of Distribution of Ventilation in Pediatrics Requiring Mechanical Ventilation by Electrical Impedance Tomography October 1, 2014 November 4, 2018
NCT04670939 Completed N/A Respiratory Physiotherapy in Mechanical Ventilation July 20, 2018 August 1, 2019
NCT02265198 Completed Relationship of Pulmonary Contusion to Pulmonary Inflammation and Incidence of Acute Respiratory Distress Syndrome September 2014 March 2015
NCT02265458 Completed N/A Musical Intervention in Non-invasive Ventilation May 2015 January 2017
NCT02284178 Completed N/A Oral Suction Intervention to Reduce Aspiration and Ventilator Events: NO-ASPIRATE August 2014 December 2017
NCT02289131 Completed N/A Frequency of Oral Care Intervention Study December 31, 2014 March 20, 2018
NCT04641182 Completed Prone Position for Nonintubated Patients With COVID-19 and Hypoxemic Respiratory Failure July 6, 2020 September 16, 2020
NCT04633772 Completed Phase 1/Phase 2 Use of Angiotensin-(1-7) in COVID-19 August 5, 2020 November 1, 2021
NCT02293616 Completed N/A Strength Testing After Nitrate Delivery (STAND) in ICU Patients June 2015 April 2017
NCT04632602 Completed N/A Awake Prone Position to Reduce Ventilation Inhomogeneity in COVID-19 Acute Respiratory Failure April 14, 2020 December 31, 2020
NCT02344043 Completed Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness March 2014 September 2016
NCT02377830 Completed Phase 2 CYCLE Pilot Randomized Trial March 2015 December 2018
NCT02382861 Completed N/A Conventional vs Neurally Adjusted Ventilatory Assist in Difficult Weaning From Mechanical Ventilation February 20, 2015 January 2017
NCT02389166 Completed N/A Optiflow in Sequential Non-Invasive Ventilation June 25, 2015 March 5, 2019
NCT02393274 Completed Microcirculation in Venoarterial Extracorporeal Membrane Oxygenation Life Support April 2015 December 2016
NCT02398981 Completed N/A Implementation of a Web Based Real Time Clinical Decision Support Tool. February 2015 December 31, 2018
NCT04611269 Completed Clinical Characteristics and Outcomes of Patients With COVID-19 on Mechanical Ventilation in Argentina March 20, 2020 October 31, 2020
NCT04582838 Completed Photoplethysmographic Scaling of Dyspnoea October 1, 2020 July 30, 2021
NCT02462668 Completed N/A Fibreoptic Bronchoscopy Assisted Intubation During Noninvasive Positive Pressure Ventilation June 2015 June 18, 2017
NCT02480205 Completed N/A A Pilot Study of Synchronized and Non-invasive Ventilation ("NeuroPAP") in Preterm Newborns August 2015 January 30, 2017
NCT02481843 Completed Hyperoxia, Erythropoiesis and Microcirculation in Critically Ill Patient April 2013 March 2015
NCT02482870 Completed N/A Efficiency of the King Vision Video Laryngoscope January 2014 November 2014
NCT02488174 Completed N/A Prevention of Severe Acute Respiratory Failure in Patients With PROOFCheck August 2015 September 2018
NCT04547283 Completed N/A Awake-Prone Positioning Strategy for Hypoxic Patients With COVID-19 June 14, 2020 September 30, 2020
NCT04521426 Completed Ventilator-associated Injury (VAI) in Chronic Home Mechanical Ventilation October 1, 2020 September 1, 2023
NCT02497729 Completed Phase 4 Checklists and Upright Positioning in Endotracheal Intubation of Critically Ill Patients (Check-UP) Trial July 2015 September 2016
NCT02499276 Completed N/A Comparative Effects of Variable Pressure Support, NAVA and PAV May 2015 December 2015
NCT02526862 Completed Phase 4 Prevention of Pressure Ulcers in Patients Under Non-Invasive Mechanical Ventilation February 2012 August 2013
NCT02533622 Completed Holy Name Progressive Mobility in the ICU January 2011 January 2013
NCT04505592 Completed Phase 2 Tenecteplase in Patients With COVID-19 September 25, 2020 March 10, 2022
NCT02560129 Completed MICU Recovery Clinic July 2015 November 30, 2023
NCT04476914 Completed Stress Related Disorders in Family Members of COVID-19 Patients Admitted to the ICU June 29, 2020 June 15, 2021
NCT02683772 Completed Phase 3 Astral VAPS AutoEPAP Clinical Trial April 15, 2016 July 6, 2017
NCT02685930 Completed Pneumonia in the Intensive Care Unit (ICU) Setting January 2016 February 1, 2017
NCT04471220 Completed N/A Exercise Capacity Under Various FiO2 and Oxygen Flow Rates Using HFNC July 1, 2020 September 29, 2022
NCT04457505 Completed One Year Follow-ups of Patients Admitted to Spanish Intensive Care Units Due to COVID-19 May 8, 2020 December 31, 2021
NCT02696018 Completed Diaphragmatic Echography in Critically Ill patientS July 2014 March 2015
NCT02708862 Completed N/A Four Methods of Pre-oxygenation March 2016 March 2016
NCT04452708 Completed HFNC and NIV for COVID-19 Complicated by Respiratory Failure June 11, 2020 April 30, 2022
NCT02787681 Completed N/A Multi-center Evaluation of the NEMO Gauge to Aid in Correct Positioning of the Endotracheal Tube August 15, 2016 July 14, 2017
NCT02798302 Completed N/A Bag Valve Mask vs Non-rebreather at Flush Rate June 2016 September 2016
NCT02814994 Completed N/A Respiratory System Compliance Guided VT in Moderate to Severe ARDS Patients September 2012 June 2014
NCT02875379 Completed N/A Clinical Comparison of Different Humidification Strategies During Noninvasive Ventilation With Helmet February 1, 2017 January 23, 2019
NCT04420741 Completed Phase 2 Infusion of Prostacyclin (Iloprost) vs Placebo for 72-hours in COVID-19 Patients With Respiratory Failure June 15, 2020 April 23, 2021
NCT04419376 Completed Driving Pressure and Mortality: in the Pediatric Intensive Care Unit (PICU) March 30, 2018 April 15, 2020
NCT02967809 Completed Usefulness of an Ultraportative Ultrasound Device in the Management of Intra Hospital Emergencies October 2016 September 2019
NCT02987036 Completed N/A Delivery of Beta Agonists is Technique Sensitive (DOBATS)Mechanics January 2015 November 2016
NCT02992002 Completed Influence of Fluid Challenge on End-Expiratory Lung Impedance in Mechanically Ventilated Patients Monitored With Electrical Impedance Tomography December 2016 December 2017
NCT03008174 Completed N/A Early Speech With One-Way Speaking Valve in Tracheostomy Patients February 5, 2016 December 5, 2019
NCT03026322 Completed N/A Preventing Hypoxemia With Manual Ventilation During Endotracheal Intubation (PreVent) Trial March 15, 2017 July 6, 2018
NCT03062917 Completed N/A Nasal and Bronchial Absorption Sampling in RSV Bronchiolitis October 2, 2015 June 30, 2018
NCT03064659 Completed Driving Pressure And EFL in Adult Cardiac Surgery November 2015 May 2017
NCT03098524 Completed N/A Low Tidal MEChanical Ventilation Against NO Ventilation During Cardiopulmonary Bypass Heart Surgery May 2, 2017 August 29, 2019
NCT04410783 Completed N/A The Emergency Department Sedation Pilot Trial September 14, 2020 May 28, 2022
NCT04407260 Completed Use of Oxygen Hoods in Patients Failing on Conventional High-flow Oxygen Delivery Systems, Effects on Oxygenation in Hypoxic COVID-19 Patients. Prospective Cohort Study. March 6, 2020 May 1, 2020
NCT03141294 Completed N/A Reformative Versus Single Step Dilation Percutaneous Dilatational Tracheostomy July 1, 2012 February 15, 2017
NCT04395144 Completed N/A COVid-19: Awake Proning and High-flow Nasal Cannula in respiratorY DistrEss May 15, 2020 March 15, 2021
NCT03157466 Completed Respiratory Muscle Function After Thyroid Hormone Replacement Therapy in Nonthyroidal Illness Syndrome October 1, 2017 May 1, 2018
NCT03163823 Completed N/A CTSI-iPad for Vented Patient Communication February 23, 2017 September 21, 2020
NCT04391634 Completed N/A Cerebral and Circulatory Effects of Neonatal Volume Targeted Ventilation August 1, 2017 May 30, 2018
NCT04386694 Completed N/A Photobiomodulation Therapy Combined With Static Magnetic Field in Patients With COVID-19 May 18, 2020 September 17, 2020
NCT03194750 Completed N/A Ultrasound Assessment of Volume in Patients on Continuous Dialysis June 1, 2016 September 7, 2023
NCT03201263 Completed N/A Sigh in Acute Hypoxemic Respiratory Failure December 20, 2017 May 9, 2019
NCT04379544 Completed Prognostic Value of Point of Care Cardiac and Lung Ultrasound in COVID-19 April 23, 2020 December 1, 2021
NCT03239730 Completed Arterial pH Selectively Predicts Intensive Care Unit Transfer From the Emergency Department in Obese Patients With Acute Dyspnea May 23, 2013 May 30, 2014
NCT03271671 Completed N/A Pressure Support Ventilation (PSV) Versus Neurally Adjusted Ventilator Assist (NAVA) During Acute Respiratory Failure (ARF) October 1, 2017 March 31, 2019
NCT03287466 Completed N/A Targeted OXYgen Therapy in Critical Illness January 15, 2018 February 15, 2020
NCT03327610 Completed N/A Selecting the Best Ventilator Hyperinflation Settings July 2016 August 2017
NCT03337373 Completed Phase 4 The Study of Pharmacokinetics and Pharmacodynamics of Cisatracurium December 15, 2017 August 31, 2018
NCT03342781 Completed N/A Using HFNC in Bronchiolitis March 1, 2016 March 1, 2017
NCT04368377 Completed Phase 2 Enhanced Platelet Inhibition in Critically Ill Patients With COVID-19 April 6, 2020 April 23, 2020
NCT03379779 Completed Evaluation the Association of Microbiome Between Respiratory Tract Samples and Stool Samples in Pneumonic Patients Accompanied by Respiratory Failure August 28, 2017 September 1, 2019
NCT03388437 Completed N/A Non-invasive Neurally Adjusted Ventilatory Assist Versus Nasal Intermittent Positive Pressure Ventilation for Preterm Infants After Extubation May 1, 2017 April 30, 2019
NCT03406936 Completed N/A Sedation and Ease of Weaning From Mechanical Ventilation August 20, 2016 October 30, 2017
NCT03440593 Completed N/A Indirect Calorimetry Usage and Effect in Ventilator-free Days and Muscle Thickness in Septic Ventilated Patients September 10, 2018 October 3, 2019
NCT03443479 Completed Comparison of High-flow Oxygen vs. BiPAP in Type II (Hypercapnic) Respiratory Failure April 1, 2015 July 1, 2019
NCT03452046 Completed Inferior Vena Cava Indexes in Positive Pressure Supports September 1, 2016 March 15, 2018
NCT03462524 Completed Neoadjuvant Therapy for Esophageal Cancer and Cardiopulmonary Physiology January 1, 2010 January 1, 2018
NCT03464695 Completed N/A Automated Oxygen Delivery by O2matic to Patients Admitted With an Exacerbation in COPD May 7, 2018 August 8, 2018
NCT04361591 Completed COVID-19 in Liver Transplant Recipients March 1, 2020 March 1, 2021
NCT03944967 Completed Postoperative Remote Monitoring of Vital Signs in Older Cardiac Surgery Patients March 5, 2020 December 19, 2021
NCT03978728 Completed Analysis of Endotoxin Activity in Patients With ECMO August 21, 2019 February 28, 2021
NCT00142766 Completed Phase 2 Sedation Management in Pediatric Patients Supported on Mechanical Ventilation February 2004 March 2007
NCT06291636 Completed Re- Admission Rate Among Survived Patients With Acute Respiratory Failure January 1, 2023 January 20, 2024
NCT06249659 Completed Impact of Extubation Location After Surgery on Perioperative Times September 1, 2020 February 1, 2023
NCT00248729 Completed Phase 2 Effectiveness and Safety Study of Etomidate Versus Midazolam to Help Place a Breathing Tube Outside of the Hospital. October 2002 November 2005
NCT00282594 Completed N/A The Effect of Intensive Insulin Therapy in the Surgical Critical Care Unit July 2003 October 2005
NCT06208592 Completed Comparative Study of Anaconda System Use Versus Conventional Sedation in COVID-19 Patients. May 30, 2020 November 6, 2020
NCT06159465 Completed Utility of Defining ARDS and Past and Current Definitions of ARDS December 13, 2023 April 15, 2024
NCT00297986 Completed Evaluation of Different Interfaces for Noninvasive Positive Pressure Ventilation (NPPV) June 2004 December 2014
NCT03943914 Completed N/A Early Non-invasive Ventilation and High-flow Nasal Oxygen Therapy for Preventing Delayed Respiratory Failure in Hypoxemic Blunt Chest Trauma Patients. September 25, 2019 November 9, 2021
NCT03978845 Completed N/A Phrenic Nerve Block to Mitigate Self-inflicted Lung Injury May 15, 2019 September 9, 2020
NCT03537937 Completed N/A Pragmatic Investigation of optimaL Oxygen Targets Trial July 1, 2018 January 31, 2022
NCT04358003 Completed N/A Plasma Adsorption in Patients With Confirmed COVID-19 May 20, 2020 April 1, 2022
NCT03557645 Completed N/A Ventilator Hyperinflation and Hemodynamics November 5, 2017 September 30, 2018
NCT04357730 Completed Phase 2 Fibrinolytic Therapy to Treat ARDS in the Setting of COVID-19 Infection May 14, 2020 September 30, 2021
NCT03591250 Completed Healthcare Renunciation in Respiratory Chronic Disease and Treatment Compliance (OBSERVE) December 7, 2018 August 29, 2022
NCT03616054 Completed International Observational Study on Airway Management in Critically Ill Patients October 1, 2018 September 30, 2019
NCT04355780 Completed Immunologic Features of Respiratory Failure in Pediatric Hematopoietic Cell Transplantation (HCT) Recipients and Pediatric Oncology Patients January 8, 2021 August 30, 2023
NCT03643939 Completed N/A High-Flow Nasal Oxygen Cannula Compared to Non-Invasive Ventilation in Adult Patients With AcuTE Respiratory Failure November 1, 2019 February 28, 2024
NCT03661086 Completed N/A Oxygen Control and Weaning by O2matic to Patients Admitted With an Exacerbation of COPD December 1, 2018 June 30, 2022
NCT04354584 Completed Compartmental Inflammation in Mechanically Ventilated Patients With COVID-19 April 6, 2020 January 10, 2022
NCT04347031 Completed Phase 2/Phase 3 A Study of the Effectiveness of an Off Label Mefloquine Use for the Treatment of Patients With COVID19 April 8, 2020 November 20, 2020
NCT04324528 Completed N/A Cytokine Adsorption in Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation March 27, 2020 January 27, 2021
NCT04291508 Completed Phase 2 Acetaminophen and Ascorbate in Sepsis: Targeted Therapy to Enhance Recovery October 13, 2021 July 27, 2023
NCT03721237 Completed N/A Esophageal Balloon Calibration in Assisted Ventilation Mode November 15, 2018 August 1, 2019
NCT03724643 Completed N/A Protocolized Ventilator Weaning Verses Usual Care October 18, 2007 August 20, 2017
NCT04284891 Completed Critical Respiratory Diseases in Ex-preterm Infants in PICU November 1, 2019 May 30, 2021
NCT03742167 Completed N/A Pilot Simulation RCT of Telemedical Support for Paramedics December 18, 2018 July 12, 2022
NCT03744169 Completed Use of Lung Ultrasound to Diagnose the Etiology of Respiratory Failure in a PICU. December 1, 2018 February 29, 2020
NCT04241861 Completed N/A High-flow Nasal Cannula vs. Helmet PSV vs. Helmet CPAP During Respiratory Failure January 22, 2020 January 27, 2021
NCT04191239 Completed Comparing Two Different Modes of Ventilation in Pretem Neonates Bilevel VG and PRVC January 1, 2021 June 30, 2021
NCT04146753 Completed Identifying and Understanding Risk Factors for Instability and Adverse Events Associated With Chest Physiotherapy in Ventilated Children July 29, 2020 November 22, 2021
NCT04140682 Completed N/A Proportional Assisted Ventilation and Pressure Support Ventilation in Adult Patients With Prolonged Ventilation May 1, 2010 April 30, 2011
NCT04123730 Completed N/A Automated Oxygen Titration During Walking in Patients With COPD October 28, 2019 December 1, 2020
NCT04103996 Completed Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation February 10, 2020 December 31, 2021
NCT03832387 Completed N/A Non-invasive Ventilation vs Oxygen Therapy After Extubation Failure March 29, 2009 September 4, 2016
NCT04081155 Completed Effect of PEEP on Lung Regional Ventilation and Perfusion January 1, 2019 June 1, 2020
NCT04081142 Completed Application of Indicator Based-electrical Impedance Tomography Method Assess Lung Regional Perfusion in ICU Patients May 1, 2018 July 31, 2020
NCT03873675 Completed Parathyroid Hormone Kinetics During CRRT May 6, 2019 November 1, 2020
NCT04035915 Completed N/A Comparison Between Limited Driving Pressure Ventilation and Conventional Mechanical Ventilation Strategies in Medical Intensive Care Patients With Acute Respiratory Failure July 25, 2019 March 31, 2021
NCT04030208 Completed N/A Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation September 4, 2018 December 31, 2019
NCT04004481 Completed Metabolites of Tramadol in the Postoperative Surgical Patients January 25, 2019 March 13, 2020
NCT00148642 Completed Phase 3 Silver-Coated Endotracheal Tube to Reduce Ventilator Associated Pneumonia (VAP) November 2002 March 2006
NCT03909854 Completed N/A Pragmatic Investigation of Volume Targeted Ventilation-1 September 9, 2019 February 20, 2020
NCT03911947 Completed N/A Evaluation of the Effectiveness of Vibroacoustic Therapy in the Complex Treatment of Acute Respiratory Failure May 2, 2019 July 31, 2020
NCT05081895 Enrolling by invitation Ventilation and Perfusion in the Respiratory System August 19, 2021 July 2024
NCT05462600 Enrolling by invitation Distribution of Ventilation, Respiratory Drive and Gas Exchange: Measurements and Monitoring July 19, 2022 June 30, 2025
NCT06454006 Not yet recruiting N/A Effects of PBMT-sMF in Mechanically Ventilated Patients June 2024 December 2025
NCT03897920 Not yet recruiting Doppler Ultrasound Renal Arterial Resistive Indices As Predictor Of Multiorgan Failure In Patients With Acute Hypoxic Respiratory Failure Admitted To Respiratory Intensive Care Unit (Cryptic Shock Index- RICU) January 1, 2023 January 1, 2025
NCT04213911 Not yet recruiting Comparison of Esophageal Manometry and CT Scan Measurements March 2023 December 2023
NCT04728412 Not yet recruiting N/A High Flow Oxygen Therapy in Patients Undergoing Bronchoscopy Under Sedation September 1, 2024 December 30, 2025
NCT05014581 Not yet recruiting Phase 3 Preventing Cardiovascular Collapse With Vasopressors During Tracheal Intubation January 2024 December 2024
NCT05282238 Not yet recruiting Quantification of Inspiratory Effort Through Nasal Pressure in Patients Undergoing Weaning From Invasive Mechanical Ventilation and Correlation With Clinical Outcomes May 1, 2022 December 31, 2024
NCT05647096 Not yet recruiting N/A Safety, Tolerability and Performance of the NucleoCapture Device in the Reduction of Circulating cfDNA/NETs in Subjects With Sepsis August 1, 2024 May 28, 2026
NCT05680545 Not yet recruiting N/A Volatile Anesthetic Pharmacokinetics During Extracorporeal Membrane Oxygenation July 1, 2024 June 30, 2025
NCT05697016 Not yet recruiting N/A Sivelestat for Acute Respiratory Distress Syndrome Due to COVID-19 January 31, 2023 January 31, 2024
NCT05869045 Not yet recruiting POCUS and Respiratory Failure Prognosis Based on Diaphragmatic Dysfunction September 1, 2023 May 1, 2024
NCT05955534 Not yet recruiting N/A Concomitant Bedside Percutaneous Tracheostomy and Ultrasound Gastrostomy May 2024 December 1, 2026
NCT06029699 Not yet recruiting N/A High Flow Nasal Cannula Versus Non Invasive Positive Pressure Ventilation in Reducing The Rate of Reintubation October 1, 2023 October 1, 2026
NCT06064409 Not yet recruiting Optimal Timing and Failure Prediction of High Flow Nasal Cannula Oxygen Therapy in Emergency Department: Prospective Observational Single Center Study November 1, 2023 March 2025
NCT06066502 Not yet recruiting Phase 3 Precision Ventilation vs Standard Care for Acute Respiratory Distress Syndrome April 1, 2024 August 31, 2030
NCT06102499 Not yet recruiting Comparison of Pulse Oximetry (SpO2) With Different Oximeters and Arterial Saturation (SaO2): Oxygap2 Study June 2024 December 30, 2025
NCT06220825 Not yet recruiting PRactice of VENTilation in Critically Ill PEDiatric Patients April 1, 2024 April 1, 2034
NCT06244160 Not yet recruiting N/A High Flow Oxygen Therapy After Spinal Cord Injury March 2024 June 2025
NCT06292767 Not yet recruiting Cardiopulmonary Bypass on Mechanical Power and Postoperative Pulmonary Complications March 15, 2024 April 25, 2025
NCT06308926 Not yet recruiting Phase 2 MRG-001 as an Immunoregulatory and Regenerative Therapy for ARDS Patients July 1, 2024 July 1, 2026
NCT06395532 Not yet recruiting Integrated Pulmonary Index as a Predictor of Respiratory Compromise in Critically Ill Patients May 15, 2024 December 22, 2024
NCT06439875 Not yet recruiting N/A Effects of L-arginine and Liposomial Vitamin C on Severe Copd Patients Undergoing Pulmonary Rehabilitation. July 1, 2024 July 1, 2025
NCT06443970 Not yet recruiting N/A Low and High Flow Suctioning in Intubated Infants June 30, 2024 October 31, 2025
NCT05508724 Recruiting Recruitment Manoeuvres in Critically Ill Patients October 1, 2022 December 1, 2024
NCT05479773 Recruiting N/A Safety and Usability of the LUMENA Non-invasive Ventilation Mask June 23, 2022 June 22, 2023
NCT05456542 Recruiting Phase 3 Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients April 5, 2023 November 30, 2024
NCT05380687 Recruiting N/A Time Course of Neuro-ventilatory Efficiency During a Spontaneous Breathing Training June 15, 2022 December 31, 2024
NCT06040138 Recruiting Monitoring of Breathing Effort Through Pressure Time Product Measurement Using Airway Occlusion Pressure October 1, 2023 July 1, 2024
NCT05355974 Recruiting Phase 3 Using Vasopressor Medication to Support Blood Pressure During Intubation Procedure August 9, 2022 June 2024
NCT04664192 Recruiting Bio-Banking of Specimens for Advanced Lung Disease and Lung Transplant Research June 4, 2021 December 1, 2026
NCT05328492 Recruiting N/A Volume Mode Non-invasive Ventilation in Amyotrophic Lateral Sclerosis March 15, 2022 March 15, 2024
NCT05308719 Recruiting N/A Nasal Oxygen Therapy After Cardiac Surgery September 8, 2020 June 30, 2025
NCT06039501 Recruiting N/A The Family Perspectives Project Pilot Trial October 13, 2023 October 2025
NCT05261607 Recruiting Analysis of the Evolution of Mortality in an Intensive Care Unit July 1, 1991 December 31, 2026
NCT05211661 Recruiting Diaphragm Atrophy and Dysfunction in Mechanical Ventilation October 10, 2022 December 1, 2023
NCT06203405 Recruiting N/A The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial December 22, 2023 June 30, 2025
NCT04236726 Recruiting Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure December 19, 2019 May 31, 2025
NCT05089695 Recruiting N/A Helmet NIV vs. CPAP vs. High-flow Nasal Oxygen in Hypoxemic Respiratory Failure March 1, 2022 June 2026
NCT04772183 Recruiting OxyGap : Comparison Between Different Pulse Oximeter and With the Arterial Blood Gase March 24, 2021 June 30, 2025
NCT04908449 Recruiting Phase 1 Pectointercostal Fascial Plane Block (PIFB) Alone Versus PIFB With Rectus Sheath Block (RSB) in Cardiac Surgery June 19, 2023 December 2024
NCT06452966 Recruiting N/A The Impact and Effect of Traditional Chinese Medicine Treatment on Organ Failure in Critically Ill Patients May 7, 2024 May 30, 2027
NCT05990348 Recruiting Estimation of the Diaphragm Electrical Activity and Intercostal Thickening Fraction During Different Pattern of Mechanical Ventilation: PSV Versus NAVA July 1, 2022 December 30, 2024
NCT05990101 Recruiting N/A HYPoxaEmic Respiratory Failure and Awake Prone Ventilation May 12, 2023 September 1, 2028
NCT05964075 Recruiting RASECAL-Bronchoscopic Ambusampler January 14, 2022 May 31, 2024
NCT04079465 Recruiting N/A Automated Oxygen Control by O2matic to Patients Admitted With Acute Hypoxemia October 1, 2019 December 31, 2024
NCT06295900 Recruiting N/A The Effect of Aromatherapy Massage on Sleep Quality January 5, 2024 December 2024
NCT06174636 Recruiting N/A Lung Overdistension and Abdominal Pressure Rise June 20, 2023 June 2025
NCT05952726 Recruiting N/A Inspiratory Effort at Different Expiratory Cycling and Airway Resistance During Pressure Support Ventilation (CYCLOPES) August 1, 2023 September 1, 2024
NCT05893420 Recruiting N/A A Rapid Diagnostic of Risk in Hospitalized Patients Using Machine Learning December 1, 2022 June 30, 2025
NCT05883137 Recruiting High-flow Nasal Oxygenation for Apnoeic Oxygenation During Intubation of the Critically Ill September 25, 2023 June 30, 2025
NCT03802383 Recruiting The Relationship Between Trans-diaphragmatic Pressure and Diaphragmatic Contraction June 29, 2018 June 30, 2024
NCT05520762 Recruiting N/A Hospital Airway Resuscitation Trial February 6, 2023 February 2027
NCT05495477 Recruiting N/A Effects of NIV and CPAP on Ventilation Distribution, Measured by EIT, During Deep Sedation in Paediatric Patients April 20, 2021 October 30, 2024
NCT03880084 Recruiting Delirium, Agitation/Sedation, Pain and Dyspnea in Respiratory Intensive Care Unit (NIVILIUM) August 1, 2019 January 1, 2025
NCT06409897 Recruiting N/A Respiratory Mechanics Assessment at Different Head of the Bed Elevations in Mechanically Ventilated Patients October 15, 2023 April 1, 2025
NCT05861323 Recruiting N/A Feasibility of the Comfort Measures Only Time Out (CMOT) October 20, 2023 August 31, 2025
NCT03141619 Recruiting Cerebral Oxygenation and Neurological Outcomes FOllowing CriticAL Illness-2 October 13, 2017 June 2025
NCT05855213 Recruiting N/A HVNI for Successful Weaning in Respiratory Failure April 1, 2023 July 2024
NCT05843123 Recruiting Phase 4 Comparison of Gas Exchange Between Two Invasive Mechanical Ventilation Modes in Children January 15, 2024 July 2024
NCT05755425 Recruiting CPAP Versus HFNO for the Treatment of Acute Hypoxemic Respiratory Failure Due to Community Acquired Pneumonia February 22, 2022 January 30, 2024
NCT06341972 Recruiting N/A Improving Psychological Outcomes for Acute Respiratory Failure Survivors Using a Self-Management Intervention May 31, 2024 September 1, 2027
NCT06310629 Recruiting N/A Oxygenation Efficacy of "Intrinseque Health" Non-Rebreathing Mask ("IHNRM") February 22, 2024 May 21, 2025
NCT05751863 Recruiting N/A Analgesia-First Sedation in Trauma Patients April 1, 2023 September 1, 2025
NCT03753412 Recruiting Recovery From ICUAW Following Severe Respiratory and Cardiac Failure April 9, 2019 September 26, 2024
NCT06057688 Recruiting Construction of Early Warning Model for Pulmonary Complications Risk of Surgical Patients Based on Multimodal Data Fusion August 1, 2023 December 31, 2024
NCT05714527 Recruiting N/A Closed-Loop O2 Use During Invasive Mechanical Ventilation Of Pediatric Patients January 30, 2023 August 31, 2024
NCT05652699 Recruiting N/A Effect of HFNO Therapy on Respiratory Effort After Extubation October 1, 2022 December 31, 2024
NCT06401083 Recruiting Phase 4 The Effect of an Additional Pre-extubational Loading Dose of Caffeine-citrate December 21, 2023 December 2028
NCT05643911 Recruiting N/A Effects of High-flow Oxygen Therapy and Non-invasive Ventilation on Lung Volumes and on Upper Airway January 27, 2023 January 2025
NCT05637645 Recruiting N/A Different Approaches of Spinal Anesthesia in Patients Undergoing Cesarean Section November 22, 2022 January 31, 2023
NCT05635903 Recruiting N/A Jet or Vibrating Mesh Nebulisation for Secretion Management in ICU December 22, 2019 December 22, 2023
NCT05617079 Recruiting The State of Nebulizer Therapy in Russian Federation July 1, 2023 July 31, 2024
NCT04542096 Recruiting Real Time Evaluation of Dynamic Changes of the Lungs During Respiratory Support of VLBW Neonates Using EIT September 29, 2020 September 2024
NCT04545541 Recruiting Phase 2/Phase 3 Nebulised Heparin in Patients With Severe COVID-19 November 1, 2020 June 2024
NCT05590130 Recruiting N/A Comparison of Two Oxygenation Targets With Two Different Oximeters - Impact on Oxygen Flow Rates and Oxygenation November 16, 2022 June 30, 2025
NCT05535543 Recruiting Change in the Phase III Slope of the Volumetric Capnography by Prone Positioning in Acute Respiratory Distress Syndrome September 6, 2022 June 30, 2023
NCT05530434 Recruiting N/A Transpulmonary Pressure Guided Mechanical Ventilation Weaning in Obesity April 11, 2022 April 30, 2025
NCT05527704 Recruiting Phase 3 the Inhaled β2-adrenergic Receptor Agonist for Transient Tachypnoea of the Newborn (the REFSAL Trial) December 31, 2021 September 30, 2026
NCT03667027 Recruiting Diaphragm Structure and Pathobiology in Patients Being Bridged to Lung Transplant April 1, 2019 December 30, 2024
NCT04385771 Suspended N/A Cytokine Adsorption in Patients With Severe COVID-19 Pneumonia Requiring Extracorporeal Membrane Oxygenation September 1, 2020 October 31, 2021
NCT04026217 Suspended Diaphragm Ultrasound as a Powerful Tool in Managing Acute Hypoxemic Respiratory Failure in Hematological Patients May 27, 2019 January 31, 2024
NCT04368000 Terminated N/A Prone Positioning in Awake Patients With COVID-19 Requiring Hospitalization April 29, 2020 August 6, 2020
NCT04269681 Terminated N/A RENOVATE Palliative: HFNC vs. Standard Respiratory Support in Patients With Do-Not-Intubate Order and ARF December 1, 2020 August 9, 2021
NCT03682874 Terminated Identifying Novel Aging Targets for Treatment of Delirium October 10, 2018 February 20, 2020
NCT04339816 Terminated Phase 3 Azithromycin Added to Hydrochloroquine in Patients Admitted to Intensive Care With COVID-19: Randomised Controlled Trial May 13, 2020 November 4, 2020
NCT03625687 Terminated Phase 4 Pan-genotypic Direct Acting Antiviral Therapy in Donor HCV-positive to Recipient HCV-negative Lung Transplant February 5, 2019 April 4, 2022
NCT03512067 Terminated N/A Entrainment-Based Mechanical Ventilation August 1, 2018 September 2, 2018
NCT04382391 Terminated N/A Study Assessing Vagus Nerve Stimulation in CoViD-19 Respiratory Symptoms May 15, 2020 April 13, 2023
NCT03180385 Terminated N/A NAVA Versus BiPAP Non-Invasive Respiratory Support in Infants Following Congenital Heart Surgery March 1, 2017 April 10, 2018
NCT03120793 Terminated ARDS Esophageal Balloon Pressure Changes With Positioning Study May 11, 2017 March 1, 2020
NCT04433546 Terminated Phase 2 Pemziviptadil (PB1046), a Long-acting, Sustained Release Human VIP Analogue, Intended to Provide Clinical Improvement to Hospitalized COVID-19 Patients at High Risk for Rapid Clinical Deterioration and Acute Respiratory Distress Syndrome (ARDS). July 15, 2020 December 2, 2020
NCT02760927 Terminated N/A Assessment of a Oral Endotracheal Tube Fastener on Patients Intubated With Oral Endotracheal Tubes March 2016 May 2016
NCT02686489 Terminated N/A Humidity Therapy for Spontaneously Breathing Tracheostomy Patients March 24, 2017 August 11, 2018
NCT02680704 Terminated N/A Mechanical Ventilation in Severe Brain Injury: The Effect of Positive End Expiratory Pressure on Intracranial Pressure February 2016 August 2, 2018
NCT04588792 Terminated Phase 2/Phase 3 Furosemide as Supportive Therapy for COVID-19 Respiratory Failure April 16, 2021 April 30, 2023
NCT04644276 Terminated N/A Mask Adhesive Institutional Study February 17, 2021 December 9, 2021
NCT02247895 Terminated N/A Treatment of Muscle Weakness in Critically Ill Patients December 2016 February 2018
NCT02208349 Terminated N/A King Video Laryngoscope Versus Direct Laryngoscopy for Prehospital Intubation: A Randomized Controlled Trial April 2014 April 2017
NCT02078050 Terminated N/A Volontary Inspiratory Muscles Measures Compared With Phrenic Nerves Magnetic Stimulations Measures November 2013 May 2015
NCT01820507 Terminated N/A Extubation Failure Prevention in High Risk Patients by High-flow Conditioned Oxygen Therapy vs. Standard Oxygen Therapy March 2013 January 2015
NCT01807663 Terminated N/A Validation of a Dynamic Evaluation Tool in Respiratory Failure November 2012 June 2014
NCT01751724 Terminated N/A Caffeine to Reduce Mechanical Ventilation in Preterm Infants December 2012 January 2016
NCT01717651 Terminated Muscle Atrophy in Patients With Severe Sepsis December 2011 February 2013
NCT01409031 Terminated Phase 2 Study of Sildenafil to Treat Newborns With Persistent Pulmonary Hypertension July 2011 October 2013
NCT01333059 Terminated N/A Cycling of Sedative Infusions in Critically Ill Pediatric Patients September 2010 January 2013
NCT01286506 Terminated Observational Study of Blood Pressure Measurements and Continuous Dialysis February 2011 December 2015
NCT01248845 Terminated N/A Comparative Effects on Diaphragmatic Electrical Activity and Respiratory Pattern of Various Levels of Assistance August 2010 June 2016
NCT01076816 Terminated Phase 3 Dexmedetomidine Pharmacokinetics-pharmacodynamics in Mechanically Ventilated Children With Single-organ Respiratory Failure December 2009 May 2011
NCT00826553 Terminated Phase 1 How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units January 2009 December 2013
NCT00664079 Terminated Thyroid Hormones in Critically Ill Children October 2005 December 2008
NCT00190346 Terminated N/A Comparison of Humidification Devices During Non Invasive Ventilation, in Acute Respiratory Failure December 2001 April 2003
NCT00366912 Terminated N/A Unloading Respiratory Muscles During NIV: Comparison of a Spontaneous and Auto-adjusting Controlled Mode August 2006 April 2007
NCT00292097 Terminated N/A A Prospective, Randomized Trial of Early Versus Late Tracheostomy in Trauma Patients With Severe Brain Injury February 2006 May 2008
NCT03962725 Terminated Phase 4 Avoiding Neuromuscular Blockers to Reduce Complications August 7, 2019 December 19, 2022
NCT03951064 Terminated N/A Providing Optimal PEEP During Mechanical Ventilation for Obese Patients Using Esophageal Balloon March 31, 2021 December 6, 2022
NCT03993002 Terminated N/A DAMP-Mediated Innate Immune Failure and Pneumonia After Trauma - the Harvard-Longwood (HALO) Campus Area Consortium November 15, 2019 October 1, 2021
NCT03862027 Terminated N/A Safety of Optimal PEEP in NSICU Patients March 1, 2019 March 4, 2019
NCT04085679 Terminated Multidisciplinary Mobile Unit for Preventing Hospitalization of Nursing Home Residents January 15, 2020 December 30, 2020
NCT05178212 Unknown status Characteristics and Outcomes of Patients With COVID-19 Treated With High-flow Nasal Oxygen and Awake-prone Position April 15, 2020 December 31, 2022
NCT01776333 Unknown status N/A A Randomized Controlled Trial of a Video Decision Aid in the ICU January 2013
NCT02234401 Unknown status N/A Non Invasive Ventilation for Acute Exacerbations in Adult CF August 2014 September 2017
NCT03894293 Unknown status Correlations Among Functional Performance, Muscle Strength and Weaning Rate in Mechanically Ventilated Patients February 20, 2019 February 19, 2020
NCT00174070 Unknown status Etiologies and Outcomes of Acute Respiratory Failure in Community August 2005 February 2006
NCT02035449 Unknown status Video Laryngoscopy in Pre-hospital Critical Care December 2013
NCT04930419 Unknown status Phase 3 Comparative Evaluation of the McGrath Videolaryngoscope and the Direct Laryngoscopy for Tracheal Intubation in the Prehospital Setting June 15, 2021 December 15, 2021
NCT01899352 Unknown status N/A Procedures, Complications and Follow-up of Tracheostomy in Intensive Care Units. January 2014 January 2017
NCT05007457 Unknown status N/A The Effectiveness of Respiratory Tele-rehabilitation After COVID-19 Pneumonia Related: a Randomized Controlled Trial June 12, 2021 June 12, 2023
NCT00291460 Unknown status Phase 4 Inspiratory Muscle Training in Hypercapnic COPD February 2006 March 2008
NCT01891253 Unknown status Inert Gas Rebreathing in Ventilated Patients March 2013 December 2020
NCT01838733 Unknown status Cerebral Oximetry and Perioperative Outcome in Non-Cardiac Surgery April 2014
NCT05059288 Unknown status N/A NIV Mask Assessment of Usability and Performance October 28, 2021 December 31, 2022
NCT03788096 Unknown status N/A Peer Support for Post Intensive Care Syndrome Self-Management April 20, 2020 January 27, 2021
NCT02204215 Unknown status N/A Electric Acupuncture for ICU-acquired Weakness in Mechanical Ventilation Patients January 2014 December 2015
NCT03770208 Unknown status N/A RIB PAIN (Rib Fractures Treated With Parental Analgesia With Infused LidocaiNe) June 6, 2019 June 1, 2022
NCT01806532 Unknown status Regional Lung Inflammation and Expansion in Mechanically Ventilated Patients - a PET/CT Study January 2008 March 2019
NCT01797614 Unknown status Intra-abdominal Pressures During the Spontaneous Breathing Trial January 2012 December 2013
NCT04310384 Unknown status N/A 'Single Hand Used inTubaTing Laryngoscope Evaluation' Study January 22, 2020 February 1, 2021
NCT04668313 Unknown status COVID-19 Advanced Respiratory Physiology (CARP) Study September 29, 2020 September 29, 2021
NCT04654273 Unknown status EX-PO Trial : Evaluation of the Occlusion Pressure (PO.1) in Extubation Failure November 30, 2020 January 31, 2022
NCT02290548 Unknown status N/A Effect of High-flow Nasal Oxygen on Extubation Outcome December 2014 October 2016
NCT05384314 Unknown status A Retrospective Study to Evaluate the Predictability of Abnormal Arterial Blood Gas Measurements Through Novel Observations of Continuous Trends in Electronically Measured Respiratory Rate in a Mixed Cohort of Respiratory Compromised Patients July 12, 2021 December 12, 2022
NCT05399017 Unknown status N/A Clinical Evaluation of EZVent in Hospitalized Mechanically Ventilated Patients August 1, 2022 August 30, 2022
NCT05401474 Unknown status N/A Individualization Flow in Patients Treated With High Flow Nasal Therapy (iFLOW) March 18, 2022 February 28, 2023
NCT01619280 Unknown status Phase 1 Safety Study of Nebulized Sodium Nitroprusside in Adult Acute Lung Injury May 2012 June 2013
NCT04634422 Unknown status N/A Plasma Exchange (PLEX) and Convalescent Plasma (CCP) in COVID-19 Patients With Multiorgan Failure November 16, 2020 June 30, 2022
NCT01569217 Unknown status Regional Distribution of Ventilation to Assess Respiratory Muscle Dysfunction June 2011 July 2018
NCT02292992 Unknown status N/A Lung Volume Change Between Noninvasive Positive Pressure Ventilation by Nasal Pillow and High Flow Nasal Cannula December 2014 October 2015
NCT02305914 Unknown status Follow-up Study of Complications of Acute Pancreatitis November 2014 May 2016
NCT02399878 Unknown status Intra-operative Inspiratory Oxygen Fraction and Postoperative Respiratory Complications January 2007
NCT04591509 Unknown status Predictability of Echographic Excursion of the Diaphragm for Intubation in COPD- Patients With Acute Respiratory Failure in ED July 23, 2019 July 23, 2022
NCT02491346 Unknown status Phase 4 A Trial Comparing SGC and Conventional Empiric Treatment for Glucose Control in Critically Ill Patients With Mechanical Ventilation in ICU October 2014 September 2015
NCT04550871 Unknown status A Pilot Study Investigating the Detection of Episodes of Severe Patient-Ventilator Asynchrony July 21, 2021 December 31, 2022
NCT04307459 Unknown status Acute Respiratory Failure and COVID-19 in Real Life March 19, 2020 December 31, 2020
NCT01339533 Unknown status Phase 2 Airway Pressure Release Ventilation (APRV) Versus AC/VC Conventional Ventilation October 2011 June 2016
NCT03877172 Unknown status N/A High Flow Nasal Cannula in Thoracic Surgery: a Physiologic Study February 17, 2020 December 2020
NCT02494154 Unknown status N/A Effects of Treatment With High Flow Nasal Cannulas on Respiratory Pattern and Work of Breathing Among Patients. May 2015
NCT01326208 Unknown status Phase 2 Strategies to Optimize Positive End-expiratory Pressure (PEEP) in Patients With Acute Lung Injury March 2011 June 2013
NCT04053777 Unknown status Clinical Assessment Method in Patients Using Non-invasive Ventilation August 20, 2019 September 15, 2020
NCT04538469 Unknown status Absent Visitors: The Wider Implications of COVID-19 on Non-COVID Cardiothoracic ICU Patients, Relatives and Staff September 2020 December 2021
NCT04536272 Unknown status Phase 3 Reduced Anticoagulation Targets in ECLS (RATE) October 1, 2020 March 1, 2024
NCT02495675 Unknown status N/A Effects of Treatment With High Flow Nasal Cannulas on Respiratory Pattern and Work of Breathing Among Healthy Subjects June 2015
NCT04520568 Unknown status Phase 2 High Flow Nasal Cannula Oxygen During Sedation for Video-assisted Thoracoscopic Surgery August 1, 2020 December 1, 2020
NCT02542423 Unknown status N/A Endocan Predictive Value in Postcardiac Surgery Acute Respiratory Failure. September 2015 March 2017
NCT04496362 Unknown status Phase 4 Veno-venous Extracorporeal Membrane Oxygenation (VV-ECMO) Heparin Study October 10, 2018 December 2023
NCT05655026 Unknown status N/A NIV-FOB, HFNC-FOB- Comparison of Methods January 1, 2023 December 30, 2023
NCT00221520 Unknown status Phase 3 Sedation in the Intensive Care Unit February 2003 January 2007
NCT03728491 Unknown status N/A Education and Training Competences in Thoracic Ultrasound October 31, 2018 November 1, 2019
NCT02687074 Unknown status N/A Effects of HFNC on Moderate and Severe Respiratory Failure Patients January 2016 December 2017
NCT02918786 Unknown status N/A The Efficacy of the Whisperflow CPAP System Versus Nasal High Flow in Patients at High Risk for Postextubation Failure February 2016 March 2017
NCT01155596 Unknown status Phase 2 Negative Pressure Ventilation Imapcts Weaning Ventilator In Medical Intensive Care Units (ICUs) March 2010 March 2011
NCT04079829 Unknown status Postoperative Respiratory Abnormalities September 1, 2019 October 2020
NCT00905463 Unknown status Prognosis of Lung Transplant Candidates April 2009 March 2022
NCT02936908 Unknown status Respiratory Care in Intensive Care Unit for Neuromuscular Patients August 2016 October 2017
NCT00854165 Unknown status Lung Transplantation in Respiratory Failure Patients February 2009 June 2009
NCT03119727 Unknown status N/A Clinical Evaluation of FreeO2 (Version 4) in All Patients Receiving Oxygen January 30, 2017 December 2019
NCT04392089 Unknown status Effects of Cardiovascular and Pulmonary Optimization on Cerebral Oxygenation in COVID-19 Patients With Severe ARDS May 1, 2020 May 1, 2021
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NCT03466385 Unknown status N/A NHF vs NIV in Patients With Acute Exacerbation of COPD April 15, 2018 December 31, 2021
NCT04359628 Unknown status How Does Patients' Overall Assessment of Their Health Vary Across and Within Different Disease Groups? January 2002 September 2020
NCT03543930 Unknown status Physiologic Effects of CPAP After Vascular Surgery May 25, 2018 July 1, 2019
NCT03558737 Unknown status N/A Nasal High-frequency Jet Ventilation (nHFJV) Following Extubation in Preterm Infants April 1, 2019 December 31, 2022
NCT00683072 Unknown status Patient-Ventilator Dyssynchrony: How is the Effect of Management? March 2008 December 2008
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NCT03662438 Unknown status N/A HOPE (Home-based Oxygen [Portable] and Exercise) for Patients on Long Term Oxygen Therapy (LTOT) September 9, 2018 March 20, 2020
NCT04342104 Unknown status NIV and CPAP Failure Predictors in COVID-19 Associated Respiratory Failure April 1, 2020 November 15, 2021
NCT04332666 Unknown status Phase 2/Phase 3 Angiotensin-(1,7) Treatment in COVID-19: the ATCO Trial December 30, 2021 June 15, 2023
NCT03680495 Unknown status Steroid Resistance During COPD Exacerbations With Respiratory Failure July 21, 2017 January 2021
NCT03842280 Unknown status Assessments of Diaphragm-pleural Mechanics During the Weaning From Prolonged Mechanical Ventilation February 1, 2019 December 31, 2021
NCT00526981 Unknown status N/A Prone Position for Non-intubated Patients With Acute Respiratory Failure September 2007
NCT03768232 Unknown status Ventilator Induced Diaphragm Dysfunction in Pediatric Critically Ill Patients (VIDD) January 1, 2019 January 1, 2020
NCT04092621 Unknown status Phase 4 Rapid Atrial Fibrillation Treatment Strategy September 16, 2019 September 15, 2020
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NCT03788304 Unknown status N/A High Flow Nasal Cannula Versus Non-invasive Ventilation in Prevention of Escalation to Invasive Mechanical Ventilation in Patients With Acute Hypoxemic Respiratory Failure May 1, 2019 December 1, 2020
NCT02051491 Unknown status N/A Non-invasive Ventilation for Extubation Success in Infants Less Than 1,250 Grams June 2013 December 2014
NCT04882865 Unknown status Apparatus and Method for Moving Patients May 15, 2021 February 15, 2022
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NCT02028260 Withdrawn Phase 3 Modafinil Versus Placebo for Hypoactive Delirium in the Critically Ill January 2014 October 2015
NCT04369274 Withdrawn N/A Repeated Measures Trial of Temporary Automated Manual Ventilation Versus Noninvasive Oxygenation or Conventional Vent August 2022 November 2023
NCT01280383 Withdrawn Phase 1 Non-invasive Neurally Adjusted Ventilatory Assist November 2010 May 2015
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Disase is a (Disease Ontology)
DOID:850
Cross Reference ID (Disease Ontology)
ICD10CM:J96.0
Cross Reference ID (Disease Ontology)
ICD9CM:518.81
Cross Reference ID (Disease Ontology)
NCI:C27043
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:65710008
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0264490
Exact Synonym (Disease Ontology)
acute and chronic respiratory failure
Exact Synonym (Disease Ontology)
acute respiratory Failure
Exact Synonym (Disease Ontology)
acute-on-chronic respiratory failure
Exact Synonym (Disease Ontology)
chronic respiratory failure
Exact Synonym (Disease Ontology)
respiratory insufficiency/failure
HPO alt_id (Human Phenotype Ontology)
HP:0004877
HPO Human Phenotype ID (Human Phenotype Ontology)
HP:0002878