lung disease

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Information
Disease name
lung disease
Disease ID
DOID:850
Description
"A lower respiratory tract disease in which the function of the lungs is adversely affected by narrowing or blockage of the airways resulting in poor air flow, a loss of elasticity in the lungs that produces a decrease in the total volume of air that the lungs are able to hold, and clotting, scarring, or inflammation of the blood vessels that affect the ability of the lungs to take up oxygen and to release carbon dioxide." [url:http\://www.niehs.nih.gov/health/topics/conditions/lung-disease/index.cfm, url:http\://www.nlm.nih.gov/medlineplus/ency/article/000066.htm]
Disease area statistics
[No Data.]
Chromosome band
[No Data.]
Annotation
NCT ID Status Phase Summary Start date Completion date
NCT03085069 Active, not recruiting Phase 2 A Study to Evaluate SHR-1210 in Patients With Advanced or Metastatic NSCLC May 3, 2017 August 20, 2023
NCT00013780 Completed Ozone Exposure and Dose Delivered to Human Lungs July 1998 June 2003
NCT00013949 Completed Cardiovascular Vulnerability to Particulate Exposure September 1998 September 2004
NCT00014950 Completed N/A Benefits and Risks of Newborn Screening for Cystic Fibrosis
NCT00014963 Completed Biomarkers of Benzene Exposure in Inner City Residents
NCT02234128 Completed N/A Extending Preservation and Assessment Time of Donor Lungs Using the Toronto EVLP System™ at a Dedicated EVLP Facility July 18, 2015 November 7, 2019
NCT00131274 Completed Phase 2/Phase 3 Gleevec Idiopathic Pulmonary Fibrosis (IPF) Study April 2003 August 2007
NCT00139152 Completed Phase 4 Non-invasive Ways to Evaluate Lung Disease After Treatment With Xolair September 2005 December 2009
NCT00224198 Completed Evaluation of the Lungs of Individuals With Lung Disease January 2004 September 2012
NCT00315263 Completed Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology April 2006 July 2011
NCT00455767 Completed Phase 2 Safety and Efficacy Study of Depelestat in Acute Respiratory Distress Syndrome (ARDS) Patients July 2006 September 2007
NCT00504738 Completed Lung Disease Collection (Qatar): Evaluation of the Lungs of Individuals With Lung Disease April 2006 April 2007
NCT00551642 Completed Phase 3 Safety and Efficacy Study of Nitric Oxide for Inhalation on Chronic Lung Disease in Premature Babies May 29, 2005 July 17, 2015
NCT00704171 Completed Phase 4 PleuraSeal Post Market Study (Europe) January 2008 December 2008
NCT00760071 Completed Magnetic Resonance Imaging (MRI) for Early Diagnosis of Cystic Fibrosis (CF) July 2006 September 2009
NCT00817167 Completed N/A Added Value of inReach Software on Performance Characteristics of Standard Bronchoscopy January 2009 December 2009
NCT00818025 Completed N/A Comparing Methods for Tracking Health Information at Home After Lung Transplant January 2009 January 2013
NCT00837681 Completed Pulmonary Complications of Hematopoietic Stem Cell Transplantation October 2005 July 8, 2016
NCT00843414 Completed Immunological Characterization of Bronchoalveolar Cells in Normals March 1978 April 2011
NCT00934778 Completed N/A Minimally Invasive Endoscopy in Diffuse Lung Disease June 2009 November 2016
NCT01107054 Completed Phase 1 A Study to Investigate the Effects of PF00610335 on the QT/QTC Interval in Healthy Volunteers June 2010 December 2010
NCT01153321 Completed Phase 2 Investigation of the Effect of Oral Treatment With 100 mg AZD2423 in Subjects With Mild Chronic Obstructive Pulmonary Disease (COPD) October 2010 July 2011
NCT01184118 Completed N/A DREAM: Does Inhaled Fluticasone REsult in Obstructive Sleep Apnea Manifestations? March 2009 February 2011
NCT01215279 Completed Phase 2 AZD2423 Safety and Tolerability Study in Patients With Moderate and Severe Chronic Obstructive Pulmonary Disease(COPD) October 2010 March 2011
NCT01222442 Completed Phase 1 To Evaluate the Effect of AZD3199 on the Electrical Activity in the Heart November 2010 February 2011
NCT01255592 Completed Phase 2 Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis February 2011 February 2012
NCT01289327 Completed N/A Propofol Versus Midazolam+Alfentanil for Sedation During Bronchoscopy: Comparison by Cutaneous Carbon Dioxide Tension April 2010 January 2011
NCT01404780 Completed N/A Comparison of the Glidescope and Macintosh Laryngoscope for Double Lumen Endotracheal Tube Intubation June 2011 February 2013
NCT01679301 Completed N/A Evaluation of Sleep Mode Within the Respironics SimplyGo Portable Oxygen Concentrator September 2012 July 2014
NCT01735526 Completed Lung Diffusing Capacity for Nitric Oxide and Carbon Monoxide After Hematopoietic Stem-cell Transplantation October 2012 June 2013
NCT01952002 Completed Clinical Safety for the Inspiratory Muscle Training October 2012 June 2013
NCT02055222 Completed Clinical Outcomes and Molecular Phenotypes in Smokers With Parenchymal Lung Disease October 14, 2014 August 23, 2018
NCT02112929 Completed Phase 1 Regional Lung Imaging Using Hyperpolarized Xenon Gas April 2012 September 30, 2021
NCT02217423 Completed N/A Abdominal Circumference and Cardiorespiratory Repercussions in Patients Submitted to Physical Therapy September 2014 December 2015
NCT00001303 Completed Phase 1 Effects of Endotoxin in Normal Human Volunteers April 6, 1992 May 17, 2018
NCT02345135 Completed N/A Susceptibility to Infections in Ataxia Telangiectasia September 2012 July 31, 2016
NCT02804854 Completed Phase 2 Sensing Using Neutrophil Activation Probe on the Intensive Therapy Unit December 2016 July 2022
NCT02887820 Completed N/A Evaluating the Use of Thromboelastography (TEG) in Patient's Requiring Extracorporeal Membrane Oxygenation (ECMO) December 15, 2017 December 31, 2023
NCT00052052 Completed Phase 2 An Open-Label Study of the Safety and Efficacy of Subcutaneous Recombinant Interferon-Gamma 1b (IFN-Gamma 1b) in Patients With Idiopathic Pulmonary Fibrosis (IPF) September 2002 September 2004
NCT02946658 Enrolling by invitation Phase 1/Phase 2 Use of Autologous, Adult Adipose-Derived Stem/Stromal Cells In Chronic Lung Disorders October 2016 August 14, 2025
NCT00001465 Recruiting Study of the Disease Process of Lymphangioleiomyomatosis December 18, 1995
NCT00077909 Recruiting Study of Lung Proteins in Patients With Pneumonia February 20, 2004
NCT02723474 Recruiting N/A A Single-Centre Pilot Study Exploring the Utility of Magnetic Resonance Imaging in Patients With Chronic Lung Disease November 2007 October 2025
NCT02723500 Recruiting N/A 129 Xenon MRI in Chronic Lung Disease August 2011 December 2025
NCT05933694 Recruiting N/A Spirometry Interpretation Performance of Primary Care Clinicians With/Without AI Software June 27, 2023 September 30, 2024
NCT00041548 Terminated Phase 1/Phase 2 Inhaled Nitric Oxide in Neonates With Elevated A-a DO2 Gradients Not Requiring Mechanical Ventilation May 2002 June 2005
NCT00041574 Terminated Phase 2 Hospital-Based Program for Treatment of Severe Cardiopulmonary Disease With Inhaled Nitric Oxide April 2002 December 2005
NCT00052039 Terminated Phase 3 A Randomized, Double-Blind, Three-Arm, Phase 3b Study Comparing the Safety and Efficacy of Interferon Gamma-1b With Azathioprine, and Azathioprine Alone in Patients With IPF Receiving Prednisone April 2002 June 2002
NCT00075179 Terminated Phase 4 Natrecor in Pulmonary Hypertension December 31, 2003 March 28, 2006
NCT00075998 Terminated Phase 3 The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF) December 2003 May 2007
NCT00076635 Terminated Phase 3 An Open-Label Study of the Safety of Interferon Gamma-1b in Patients With IPF November 2003 April 2007
NCT00751309 Terminated Lung Allograft Rejection Gene Expression Observational (LARGO) Study April 2004 January 2009
NCT02168036 Terminated Study of Biologic Materials From the Mediastinal Lymph Nodes From Patients With Lung Disease. August 16, 2011 February 16, 2017
NCT02188511 Terminated N/A Effects of Electronic Cigarettes on Lung Biology January 2014 July 2018
NCT02204202 Terminated PET Assessment of Acute Lung Transplant Rejection February 2014 February 4, 2017
NCT00966823 Terminated Phase 2 Fetal Tracheal Balloon Study in Diaphragmatic Hernia September 2008 January 2015
NCT02464280 Terminated Tomosynthesis of Pathologies of the Chest and Skeletal Structures in Comparison to CT May 2016 October 2020
NCT01241617 Terminated N/A ENDO GIA Stapler With Duet Tissue Reinforcement System (TRS) Used in Pulmonary Resections August 2010 January 2012
NCT01450644 Unknown status Phase 2 Evaluation of the Hospital2Home Palliative Care Service for Patients With Advanced Progressive Lung Disease October 2011 January 2013
NCT02965300 Unknown status The Value of VOCs Analysis in Exhaled Breath for Pulmonary Benign and Malignant Lesion Diagnosis October 2016 August 2017
NCT03017976 Unknown status Swimming Pool Environment Impact on the Human Respiratory Health January 2017 July 2018
NCT02191410 Unknown status Phase 3 Nondependent Lung Ventilation and Fluid Responsiveness January 2019 June 2020
NCT01090804 Unknown status Phase 2/Phase 3 The Effectiveness of BreatheMAX Breathing Device on Secretion Clearance August 2009
NCT02963467 Unknown status N/A Effect of Smoking on Ventilation-Perfusion Ratio September 17, 2018 September 2019
NCT02699268 Unknown status A Clinical Study Aiming to Validate the Equipment: VoluSense Pediatrics (VSP) December 2015 March 2016
NCT03816059 Unknown status Respiratory Virus Infections in Acutely Hospitalized Adult Patients With Pulmonary and Extrapulmonary Complications February 12, 2019 April 20, 2020
NCT02913365 Unknown status Etiologies, Investigations and Outcomes of Patients Presenting With Hemoptysis October 2012 June 2017
NCT00618852 Unknown status Phase 3 Using Furosemide to Prevent Fluid Overload During Red Blood Cell Transfusion in Neonates January 2007 June 2009
NCT02000206 Unknown status N/A Comparison of Propofol/Alfentanil With Propofol/Ketamine February 2014 December 2014
NCT02253667 Withdrawn N/A Palliative Use of High-flow Oxygen Nasal Cannula in End-of-life Lung Disease Patients September 2014 September 2015
NCT01457443 Withdrawn Biomarker for Pompe Disease (BioPompe) August 20, 2018 December 31, 2021
Disase is a (Disease Ontology)
DOID:0050161
Cross Reference ID (Disease Ontology)
ICD10CM:J98.4
Cross Reference ID (Disease Ontology)
MESH:D008171
Cross Reference ID (Disease Ontology)
NCI:C3198
Cross Reference ID (Disease Ontology)
SNOMEDCT_US_2023_03_01:266374002
Cross Reference ID (Disease Ontology)
UMLS_CUI:C0024115