chr3:52255096:> Detail (hg19)

Information

Genome

Assembly Position
hg19 chr3:52,255,096-52,259,661
hg38 chr3:52,221,080-52,225,645 

HGVS

Type Transcript Protein
Summary

MGeND

Clinical significance
Variant entry
GWAS entry
Disease area statistics Show details

Frequency

[No Data.]

Prediction

[No Data.]

ClinVar

Clinical Significance
Review star [No Data.]
Show details
Links
Disease area statistics
[No Data.]
MGeND
[No Data.]
ClinVar
[No Data.]
CIViC
[No Data.]
DisGeNET
Score Disease name Description Source Pubmed Links
<0.001 renal cell carcinoma NA BeFree Detail
0.001 squamous cell carcinoma NA BeFree Detail
<0.001 Cardiomyopathy, Dilated NA BeFree Detail
0.002 Cardiovascular Diseases NA GAD Detail
0.002 Malignant tumor of cervix TLR9 expression in uterine cervical lesions of Uyghur women correlate with cervi... BeFree 25081715 Detail
0.002 Chagas Cardiomyopathy NA GAD Detail
<0.001 Primary biliary cirrhosis NA BeFree Detail
<0.001 Cholangitis, Sclerosing NA BeFree Detail
0.002 chorioamnionitis NA GAD Detail
<0.001 colitis NA BeFree Detail
<0.001 colorectal carcinoma IFNAR1 is a predictor for overall survival in colorectal cancer and its mRNA exp... BeFree 25546690 Detail
0.004 common variable immunodeficiency NA BeFree,GAD Detail
0.002 Connective Tissue Diseases NA GAD Detail
<0.001 Coronary Arteriosclerosis NA BeFree Detail
<0.001 Coronary heart disease NA BeFree Detail
<0.001 craniosynostosis NA BeFree Detail
0.003 Cytomegalovirus Infections Incidence and dynamics of active cytomegalovirus infection in allogeneic stem ce... BeFree,GAD 25132583 Detail
0.003 Cytomegalovirus Infections In conclusion, specific SNPs in IL28B, TLR9 and DC-SIGN genes may play a role in... BeFree,GAD 25777542 Detail
0.006 Dermatitis, Atopic NA BeFree,GAD,LHGDN Detail
<0.001 Diabetes NA BeFree Detail
<0.001 diabetes mellitus NA BeFree Detail
<0.001 Diabetes Mellitus, Insulin-Dependent Altered B cell homeostasis and toll-like receptor 9-driven response in type 1 di... BeFree 25333705 Detail
<0.001 Diabetes Mellitus, Non-Insulin-Dependent NA BeFree Detail
<0.001 Dry Eye Syndromes TLR9 mRNA was significantly down-regulated by almost 59.5% in DES subjects. BeFree 25817729 Detail
<0.001 Ectromelia NA BeFree Detail
0.003 Filarial Elephantiases NA BeFree,LHGDN Detail
<0.001 Experimental Autoimmune Encephalomyelitis NA BeFree Detail
0.002 Endometrial Neoplasms NA GAD Detail
<0.001 Esophageal Neoplasms NA BeFree Detail
0.002 Fetal Diseases NA GAD Detail
0.002 Fetal Membranes, Premature Rupture NA GAD Detail
<0.001 gastritis NA BeFree Detail
0.004 glioblastoma NA BeFree,LHGDN Detail
0.001 Glioma NA BeFree Detail
<0.001 glomerulonephritis NA BeFree Detail
0.001 IgA glomerulonephritis TLR9 and BAFF: their expression in patients with IgA nephropathy. BeFree 24993857 Detail
0.003 Granuloma NA LHGDN Detail
0.120 Granuloma, Foreign-Body NA CTD_human Detail
0.120 Granuloma, Respiratory Tract NA CTD_human Detail
<0.001 chronic granulomatous disease Moreover, proliferative capabilities of B cells on selective in vitro stimulatio... BeFree 25175493 Detail
0.003 Hematological Disease NA LHGDN Detail
0.003 Hemorrhagic Fever, Crimean NA BeFree,GAD Detail
0.003 Hepatitis, Alcoholic NA LHGDN Detail
<0.001 Hepatitis, Chronic NA BeFree Detail
0.003 hepatitis C NA BeFree,GAD Detail
0.004 Herpes Simplex Infections A TLR9 inhibitory oligonucleotide containing five adjacent guanosine residues (G... BeFree,LHGDN 24995383 Detail
0.011 HIV Infections The neutrophils were stimulated with specific agonists for TLR2, TLR4 and TLR9 i... BeFree,GAD 25785697 Detail
0.002 Hypersensitivity NA GAD Detail
0.002 Immediate hypersensitivity NA GAD Detail
0.127 Inflammation NA CTD_human,GAD,LHGDN Detail
<0.001 Inflammatory Bowel Diseases Reverse transcription-PCR analysis showed that RANTES, Toll-like receptor 9, and... BeFree 25544730 Detail
<0.001 influenza NA BeFree Detail
<0.001 keratitis NA BeFree Detail
<0.001 Keratoconjunctivitis, Vernal NA BeFree Detail
<0.001 Kidney Diseases These results suggested that overexpression of TLR9 mRNA and protein in PBMCs an... BeFree 24993857 Detail
<0.001 Kidney Failure, Chronic NA BeFree Detail
0.002 Premature Obstetric Labor NA GAD Detail
<0.001 Leishmaniasis, Visceral L. donovani increases the expression of TLR4 and TLR9 in patients with VL and TL... BeFree 25982946 Detail
<0.001 leukemia NA BeFree Detail
0.002 chronic lymphocytic leukemia TLR4 and TLR9 gene expression was related to the occurrence of infections, autoi... BeFree 24144314 Detail
0.002 chronic lymphocytic leukemia TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lympho... BeFree 26136429 Detail
0.003 lymphoid leukemia NA LHGDN Detail
<0.001 Leukemia, Myelocytic, Acute The aim of this study was to investigate the associations between expression of ... BeFree 25412934 Detail
<0.001 Lung diseases NA BeFree Detail
0.002 Lung Diseases, Fungal NA GAD Detail
0.002 Tuberculosis, Pulmonary In the present study, we investigated whether variants in the TLR-1 1805T/G (Ile... BeFree 20797905 Detail
0.003 Chronic Obstructive Airway Disease NA BeFree,GAD Detail
0.005 Lung Neoplasms NA LHGDN Detail
0.004 Lupus Vulgaris Hence, this study was carried out to analyze the G to A and C to T transitions i... BeFree 25466615 Detail
0.004 Lupus Erythematosus, Discoid Hence, this study was carried out to analyze the G to A and C to T transitions i... BeFree 25466615 Detail
0.026 Lupus Erythematosus, Systemic Together with the association of several other SNPs of TLR8 and TLR9 with variou... BeFree,GAD,LHGDN 24919757 Detail
0.026 Lupus Erythematosus, Systemic Association of TLR4 (D299G, T399I), TLR9 -1486T>C, TIRAP S180L and TNF-α promote... BeFree,GAD,LHGDN 25182168 Detail
0.026 Lupus Erythematosus, Systemic Susceptibility to SLE in South Indian Tamils may be influenced by genetic select... BeFree,GAD,LHGDN 25466615 Detail
0.026 Lupus Erythematosus, Systemic In summary, G-modification of INH-ODNs improved their ability to impair TLR7- an... BeFree,GAD,LHGDN 25695778 Detail
0.026 Lupus Erythematosus, Systemic Is there association between TLR9 polymorphism and SLE susceptibility? BeFree,GAD,LHGDN 25879159 Detail
0.006 lupus nephritis NA BeFree,GAD,LHGDN Detail
0.006 lymphoma NA BeFree,GAD Detail
<0.001 Lymphoma, Non-Hodgkin NA BeFree Detail
0.013 malaria NA BeFree,GAD,LHGDN Detail
0.003 Malaria, Cerebral NA BeFree,GAD Detail
0.007 Malaria, Falciparum NA BeFree,GAD Detail
<0.001 Malignant neoplasm of stomach In conclusion, the results indicated that the TLR9/NFκB signaling pathway was in... BeFree 25369757 Detail
<0.001 meningitis NA BeFree Detail
<0.001 meningococcal meningitis NA BeFree Detail
<0.001 Meningococcemia NA BeFree Detail
0.003 molluscum contagiosum NA LHGDN Detail
<0.001 multiple myeloma NA BeFree Detail
0.003 multiple sclerosis NA BeFree,GAD Detail
0.002 Musculoskeletal Diseases NA GAD Detail
<0.001 Mycobacterium Infections NA BeFree Detail
0.001 Mycoses NA BeFree Detail
0.003 mycosis fungoides NA BeFree,LHGDN Detail
0.002 myocardial infarction NA GAD Detail
<0.001 Nasal Polyps NA BeFree Detail
0.002 Neoplasm Metastasis NA BeFree Detail
<0.001 nephritis NA BeFree Detail
0.080 Neuritis, Autoimmune, Experimental NA BeFree,RGD Detail
<0.001 neuroblastoma NA BeFree Detail
<0.001 obesity NA BeFree Detail
<0.001 Degenerative polyarthritis NA BeFree Detail
<0.001 osteosarcoma Up-regulation of Toll-like Receptor 9 in Osteosarcoma. BeFree 26504005 Detail
<0.001 ovarian carcinoma NA BeFree Detail
<0.001 Pancreatic Neoplasm NA BeFree Detail
<0.001 periodontitis Among them, IL18 (interleukin 18), CD44 (CD44 molecule), CXCL1 (chemokine [CXC m... BeFree 24476546 Detail
<0.001 periodontitis Association of pocket epithelial cell proliferation in periodontitis with TLR9 e... BeFree 25037760 Detail
<0.001 plasmacytoma NA BeFree Detail
<0.001 pneumonia NA BeFree Detail
<0.001 Pneumonia, Viral NA BeFree Detail
<0.001 polyps NA BeFree Detail
<0.001 Poxviridae Infections NA BeFree Detail
0.002 pre-eclampsia NA GAD Detail
<0.001 Precancerous Conditions NA BeFree Detail
0.002 Pregnancy Complications, Hematologic NA GAD Detail
0.003 Prostatic Neoplasms A series of preclinical studies have demonstrated the superiority of the Ad/PSA ... BeFree,LHGDN 24847764 Detail
0.001 psoriasis Toll-like receptor 9 promoter polymorphism as a predictive factor of narrow-band... BeFree 25561051 Detail
0.002 Puerperal Disorders NA GAD Detail
<0.001 Purpura, Thrombotic Thrombocytopenic NA BeFree Detail
<0.001 kidney failure NA BeFree Detail
0.005 Respiratory Syncytial Virus Infections NA BeFree,GAD Detail
<0.001 Rheumatoid Nodule NA BeFree Detail
0.003 sarcoidosis NA BeFree,GAD Detail
0.120 Schistosomiasis mansoni NA CTD_human Detail
0.002 schizophrenia NA GAD Detail
<0.001 Seizures TLR 4 T399I and TLR9 -1486 T>C showed a positive association with seizures and p... BeFree 25182168 Detail
0.002 Septicemia The aim of this study was to investigate the associations between expression of ... BeFree 25412934 Detail
0.002 Dermatologic disorders NA GAD Detail
<0.001 Stomach Diseases NA BeFree Detail
0.002 Stomach Neoplasms NA GAD Detail
0.002 Streptococcal Infections NA GAD Detail
<0.001 Carcinogenesis The findings indicate that TLR9 -1486T/C (rs187084) may contribute to cervical c... BeFree 22059466 Detail
0.002 Autoimmune Diseases Single-nucleotide polymorphism (SNP) rs187084 (T-1486C) of the TLR9 promoter is ... BeFree 25248338 Detail
<0.001 toxoplasmosis NA BeFree Detail
<0.001 Toxoplasmosis, Congenital NA BeFree Detail
0.003 Ocular Toxoplasmosis NA BeFree,GAD Detail
<0.001 Trichomonas Infections NA BeFree Detail
<0.001 Chagas disease NA BeFree Detail
0.006 tuberculosis TLR9 gene region polymorphisms and susceptibility to tuberculosis in Vietnam. BeFree,GAD 25616954 Detail
0.006 tuberculosis Other polymorphisms, including TLR9 1486C/T, did not show significant associatio... BeFree,GAD 25877346 Detail
<0.001 Tuberculosis, Meningeal This is the first demonstration of an association between a TLR9 gene region SNP... BeFree 25616954 Detail
0.002 Tuberculosis, Pulmonary In addition, this extends previous findings that support associations of TLR9 SN... BeFree 25616954 Detail
0.004 Virus Diseases NA BeFree,GAD Detail
<0.001 Wheezing NA BeFree Detail
<0.001 B-Cell Lymphomas NA BeFree Detail
<0.001 Lymphoma, Large-Cell, Follicular NA BeFree Detail
<0.001 severe combined immunodeficiency NA BeFree Detail
0.002 Bronchial Hyperreactivity NA GAD Detail
<0.001 Meningitis, Bacterial NA BeFree Detail
<0.001 acute leukemia The aim of this study was to evaluate the expression of TLR2, TLR4 and TLR9 and ... BeFree 25624047 Detail
<0.001 Chronic sinusitis NA BeFree Detail
0.001 Epstein-Barr Virus Infections These results suggest that EBV infection of NPC cells can activate the TLR9/NF-κ... BeFree 25891128 Detail
0.007 Premature Birth NA GAD Detail
<0.001 Adenocarcinoma of lung (disorder) NA BeFree Detail
<0.001 Streptococcal sepsis NA BeFree Detail
<0.001 Malignant neoplasm of mouth NA BeFree Detail
<0.001 Hearing Loss, Mixed Conductive-Sensorineural NA BeFree Detail
<0.001 allergic asthma NA BeFree Detail
0.001 Tumor Progression Our findings demonstrate that bladder cancer cell lines express functional TLR4 ... BeFree 25499923 Detail
<0.001 Adenomatous Polyps NA BeFree Detail
<0.001 Lip and oral cavity carcinoma NA BeFree Detail
<0.001 X-linked agammaglobulinemia NA BeFree Detail
<0.001 pancreatic carcinoma NA BeFree Detail
<0.001 Interstitial fibrosis NA BeFree Detail
0.006 Malignant neoplasm of lung NA BeFree,GAD Detail
0.005 Parasitemia NA BeFree,GAD Detail
<0.001 Systemic Inflammatory Response Syndrome NA BeFree Detail
0.004 Sepsis The aim of this study was to investigate the associations between expression of ... BeFree,GAD 25412934 Detail
<0.001 Chronic Periodontitis NA BeFree Detail
0.080 Pancreatitis, Acute Necrotizing NA RGD Detail
<0.001 chronic cervicitis TLR9 expression, which was mainly observed as cytoplasmic staining, gradually in... BeFree 25081715 Detail
<0.001 chronic purulent otitis media The etiology, pathological profile, expression levels of TLR2, TLR4, TLR5, TLR9 ... BeFree 24882571 Detail
<0.001 Disease due to Parvoviridae NA BeFree Detail
<0.001 Metastatic melanoma NA BeFree Detail
<0.001 Squamous cell carcinoma of esophagus NA BeFree Detail
<0.001 cervical squamous cell carcinoma TLR9 expression, which was mainly observed as cytoplasmic staining, gradually in... BeFree 25081715 Detail
<0.001 Solid tumour Preclinical and clinical studies of MGN1703 have confirmed that this TLR-9 agoni... BeFree 25577571 Detail
0.002 cervix carcinoma TLR9 expression in uterine cervical lesions of Uyghur women correlate with cervi... BeFree 25081715 Detail
0.003 Thyroid associated opthalmopathies NA BeFree,GAD Detail
<0.001 Microscopic Polyangiitis NA BeFree Detail
<0.001 Human papilloma virus infection NA BeFree Detail
<0.001 Malignant neoplasm of pancreas NA BeFree Detail
<0.001 Cervical intraepithelial neoplasia grade 1 TLR9 expression, which was mainly observed as cytoplasmic staining, gradually in... BeFree 25081715 Detail
<0.001 Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
<0.001 Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site NA BeFree Detail
0.003 Malignant neoplasm of prostate NA BeFree,GAD Detail
<0.001 Hematologic Neoplasms NA BeFree Detail
0.002 Hereditary hemochromatosis NA GAD Detail
0.002 Atopy NA GAD Detail
<0.001 Osteoarthritis, Knee NA BeFree Detail
0.007 lupus erythematosus Hence, this study was carried out to analyze the G to A and C to T transitions i... BeFree,GAD 25466615 Detail
<0.001 endometrial carcinoma NA BeFree Detail
0.002 Dermatitis and eczema NA GAD Detail
0.080 Necrotizing Enterocolitis NA BeFree,RGD Detail
<0.001 Hepatitis B, Chronic NA BeFree Detail
<0.001 Osteoarthritis, Knee The (-1486T/C) promoter polymorphism of the TLR-9 gene is associated with end-st... BeFree 21748790 Detail
0.013 malaria The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes... BeFree 21457584 Detail
0.003 Hemorrhagic Fever, Crimean Our findings suggest that TLR8 Met1Val, TLR8 -129C/G, and TLR9 -1486T/C polymorp... BeFree 20674764 Detail
<0.001 Malignant neoplasm of stomach For TLR9 -1486 T/C, multiple logistic regression analyses revealed that compared... BeFree 23776537 Detail
<0.001 primary sclerosing cholangitis TLR9 expressions were correlated with Ludwig fibrosis scores in PSC patients. BeFree 25160604 Detail
<0.001 Osteosarcoma of bone Up-regulation of Toll-like Receptor 9 in Osteosarcoma. BeFree 26504005 Detail
<0.001 Carcinogenesis NA BeFree Detail
0.001 prostate carcinoma NA BeFree Detail
0.002 breast carcinoma NA BeFree Detail
0.002 Carcinoma of lung NA BeFree Detail
<0.001 Secondary malignant neoplasm of lymph node NA BeFree Detail
<0.001 colon carcinoma NA BeFree Detail
<0.001 stomach carcinoma In conclusion, the results indicated that the TLR9/NFκB signaling pathway was in... BeFree 25369757 Detail
<0.001 Carcinoma of bladder Our findings demonstrate that bladder cancer cell lines express functional TLR4 ... BeFree 25499923 Detail
<0.001 airway disease NA BeFree Detail
<0.001 Central neuroblastoma NA BeFree Detail
<0.001 Acute GVH disease NA BeFree Detail
<0.001 Chronic graft-versus-host disease NA BeFree Detail
<0.001 Malignant neoplasm of ovary NA BeFree Detail
<0.001 Chronic inflammatory disorder NA BeFree Detail
<0.001 Herpes simplex type 1 infection NA BeFree Detail
<0.001 Esophageal Squamous Intraepithelial Neoplasia NA BeFree Detail
0.005 Mammary Neoplasms NA LHGDN Detail
<0.001 colorectal cancer IFNAR1 is a predictor for overall survival in colorectal cancer and its mRNA exp... BeFree 25546690 Detail
<0.001 Non-Neoplastic Disorder NA BeFree Detail
<0.001 Idiopathic Pulmonary Fibrosis NA BeFree Detail
0.002 Venous thromboembolism NA GAD Detail
<0.001 PHOTOPAROXYSMAL RESPONSE 1 TLR 4 T399I and TLR9 -1486 T>C showed a positive association with seizures and p... BeFree 25182168 Detail
<0.001 uterine corpus cancer NA BeFree Detail
<0.001 coronary artery disease NA BeFree Detail
0.002 liver carcinoma NA BeFree Detail
<0.001 Chronic kidney disease stage 5 NA BeFree Detail
0.003 Idiopathic Interstitial Pneumonias NA BeFree,LHGDN Detail
<0.001 Pulmonary Aspergillosis NA BeFree Detail
<0.001 Bronchopulmonary Aspergillosis NA BeFree Detail
<0.001 Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis NA BeFree Detail
<0.001 Thrombotic Microangiopathies NA BeFree Detail
0.002 Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified NA GAD Detail
0.002 Chronic ulcerative colitis NA GAD Detail
<0.001 Acute malaria NA BeFree Detail
<0.001 Nasopharyngeal carcinoma As detected by immunohistochemistry and western blotting, SPLUNC1 protein expres... BeFree 25891128 Detail
<0.001 granulomatosis with polyangiitis NA BeFree Detail
<0.001 Triple Negative Breast Neoplasms NA BeFree Detail
<0.001 Allergic disposition NA BeFree Detail
0.003 Warts NA LHGDN Detail
0.016 Infection NA GAD,LHGDN Detail
<0.001 Meningitis in children NA BeFree Detail
0.003 acquired immunodeficiency syndrome NA LHGDN Detail
<0.001 acute pancreatitis NA BeFree Detail
<0.001 extrinsic allergic alveolitis NA BeFree Detail
0.003 Alzheimer's disease NA LHGDN Detail
0.004 anemia NA BeFree,LHGDN Detail
<0.001 Refractory anaemia with excess blasts NA BeFree Detail
<0.001 Anxiety Disorders NA BeFree Detail
<0.001 arthritis NA BeFree Detail
0.004 rheumatoid arthritis Our results show that rheumatoid arthritis synovial fibroblasts (RASF) express a... BeFree,GAD 24936783 Detail
0.005 aspergillosis NA GAD Detail
0.005 Aspergillosis, Allergic Bronchopulmonary NA BeFree,GAD,LHGDN Detail
0.020 asthma NA BeFree,GAD,LHGDN Detail
0.002 atherosclerosis NA GAD Detail
0.002 Autoimmune Diseases In the past, most studies focused on the intracellular TLRs, such as TLR3, TLR7,... BeFree 24352680 Detail
<0.001 Bacteremia NA BeFree Detail
<0.001 Bacterial Infections NA BeFree Detail
0.003 Behcet Syndrome NA BeFree,GAD Detail
<0.001 Malignant neoplasm of urinary bladder Our findings demonstrate that bladder cancer cell lines express functional TLR4 ... BeFree 25499923 Detail
<0.001 Brain Neoplasms NA BeFree Detail
0.005 Malignant neoplasm of breast NA BeFree,GAD Detail
<0.001 bronchiectasis NA BeFree Detail
0.002 bronchiolitis obliterans NA GAD Detail
0.002 Bronchiolitis, Viral NA GAD Detail
<0.001 Cachexia NA BeFree Detail
<0.001 Malignant tumor of colon NA BeFree Detail
<0.001 Malignant neoplasm of endometrium NA BeFree Detail
<0.001 Non-small cell lung carcinoma NA BeFree Detail
Annotation

Annotations

DescrptionSourceLinks
NA DisGeNET Detail
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TLR9 expression in uterine cervical lesions of Uyghur women correlate with cervical cancer progressi... DisGeNET Detail
NA DisGeNET Detail
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IFNAR1 is a predictor for overall survival in colorectal cancer and its mRNA expression correlated w... DisGeNET Detail
NA DisGeNET Detail
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NA DisGeNET Detail
NA DisGeNET Detail
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Incidence and dynamics of active cytomegalovirus infection in allogeneic stem cell transplant patien... DisGeNET Detail
In conclusion, specific SNPs in IL28B, TLR9 and DC-SIGN genes may play a role in modulating the susc... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Altered B cell homeostasis and toll-like receptor 9-driven response in type 1 diabetes carriers of t... DisGeNET Detail
NA DisGeNET Detail
TLR9 mRNA was significantly down-regulated by almost 59.5% in DES subjects. DisGeNET Detail
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TLR9 and BAFF: their expression in patients with IgA nephropathy. DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Moreover, proliferative capabilities of B cells on selective in vitro stimulation of B-cell receptor... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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A TLR9 inhibitory oligonucleotide containing five adjacent guanosine residues (G-ODN) exhibited viru... DisGeNET Detail
The neutrophils were stimulated with specific agonists for TLR2, TLR4 and TLR9 in the presence of HI... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
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Reverse transcription-PCR analysis showed that RANTES, Toll-like receptor 9, and IL-4 expression lev... DisGeNET Detail
NA DisGeNET Detail
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These results suggested that overexpression of TLR9 mRNA and protein in PBMCs and elevated levels of... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
L. donovani increases the expression of TLR4 and TLR9 in patients with VL and TLR2 in THP1 cells, su... DisGeNET Detail
NA DisGeNET Detail
TLR4 and TLR9 gene expression was related to the occurrence of infections, autoimmunity and disease ... DisGeNET Detail
TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cel... DisGeNET Detail
NA DisGeNET Detail
The aim of this study was to investigate the associations between expression of TLR2, TLR4 and TLR9 ... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
In the present study, we investigated whether variants in the TLR-1 1805T/G (Ile602Ser), TLR-2 2258G... DisGeNET Detail
NA DisGeNET Detail
NA DisGeNET Detail
Hence, this study was carried out to analyze the G to A and C to T transitions in TLR2 and TLR9 gene... DisGeNET Detail
Hence, this study was carried out to analyze the G to A and C to T transitions in TLR2 and TLR9 gene... DisGeNET Detail
Together with the association of several other SNPs of TLR8 and TLR9 with various clinical and serol... DisGeNET Detail
Association of TLR4 (D299G, T399I), TLR9 -1486T>C, TIRAP S180L and TNF-α promoter (-1031, -863, -857... DisGeNET Detail
Susceptibility to SLE in South Indian Tamils may be influenced by genetic selection pressure on TLR2... DisGeNET Detail
In summary, G-modification of INH-ODNs improved their ability to impair TLR7- and TLR9-mediated sign... DisGeNET Detail
Is there association between TLR9 polymorphism and SLE susceptibility? DisGeNET Detail
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In conclusion, the results indicated that the TLR9/NFκB signaling pathway was involved in gastric ca... DisGeNET Detail
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Up-regulation of Toll-like Receptor 9 in Osteosarcoma. DisGeNET Detail
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Among them, IL18 (interleukin 18), CD44 (CD44 molecule), CXCL1 (chemokine [CXC motif] ligand 1), IL6... DisGeNET Detail
Association of pocket epithelial cell proliferation in periodontitis with TLR9 expression and inflam... DisGeNET Detail
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A series of preclinical studies have demonstrated the superiority of the Ad/PSA vaccine to other PSA... DisGeNET Detail
Toll-like receptor 9 promoter polymorphism as a predictive factor of narrow-band UVB phototherapy re... DisGeNET Detail
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TLR 4 T399I and TLR9 -1486 T>C showed a positive association with seizures and photosensitivity, res... DisGeNET Detail
The aim of this study was to investigate the associations between expression of TLR2, TLR4 and TLR9 ... DisGeNET Detail
NA DisGeNET Detail
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The findings indicate that TLR9 -1486T/C (rs187084) may contribute to cervical cancer carcinogenesis... DisGeNET Detail
Single-nucleotide polymorphism (SNP) rs187084 (T-1486C) of the TLR9 promoter is associated with vari... DisGeNET Detail
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TLR9 gene region polymorphisms and susceptibility to tuberculosis in Vietnam. DisGeNET Detail
Other polymorphisms, including TLR9 1486C/T, did not show significant associations with tuberculosis... DisGeNET Detail
This is the first demonstration of an association between a TLR9 gene region SNP and tuberculous men... DisGeNET Detail
In addition, this extends previous findings that support associations of TLR9 SNPs with pulmonary tu... DisGeNET Detail
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The aim of this study was to evaluate the expression of TLR2, TLR4 and TLR9 and their significance a... DisGeNET Detail
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These results suggest that EBV infection of NPC cells can activate the TLR9/NF-κB signaling pathway,... DisGeNET Detail
NA DisGeNET Detail
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Our findings demonstrate that bladder cancer cell lines express functional TLR4 and TLR9 with possib... DisGeNET Detail
NA DisGeNET Detail
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The aim of this study was to investigate the associations between expression of TLR2, TLR4 and TLR9 ... DisGeNET Detail
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TLR9 expression, which was mainly observed as cytoplasmic staining, gradually increased in accordanc... DisGeNET Detail
The etiology, pathological profile, expression levels of TLR2, TLR4, TLR5, TLR9 and proinflammatory ... DisGeNET Detail
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TLR9 expression, which was mainly observed as cytoplasmic staining, gradually increased in accordanc... DisGeNET Detail
Preclinical and clinical studies of MGN1703 have confirmed that this TLR-9 agonist has therapeutic p... DisGeNET Detail
TLR9 expression in uterine cervical lesions of Uyghur women correlate with cervical cancer progressi... DisGeNET Detail
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TLR9 expression, which was mainly observed as cytoplasmic staining, gradually increased in accordanc... DisGeNET Detail
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Hence, this study was carried out to analyze the G to A and C to T transitions in TLR2 and TLR9 gene... DisGeNET Detail
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The (-1486T/C) promoter polymorphism of the TLR-9 gene is associated with end-stage knee osteoarthri... DisGeNET Detail
The tlr-4 (D299G and T399I), tlr-9 (T-1486C and T-1237C) and tirap (S180L) genes were assessed in 64... DisGeNET Detail
Our findings suggest that TLR8 Met1Val, TLR8 -129C/G, and TLR9 -1486T/C polymorphisms are important ... DisGeNET Detail
For TLR9 -1486 T/C, multiple logistic regression analyses revealed that compared with the TT homozyg... DisGeNET Detail
TLR9 expressions were correlated with Ludwig fibrosis scores in PSC patients. DisGeNET Detail
Up-regulation of Toll-like Receptor 9 in Osteosarcoma. DisGeNET Detail
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In conclusion, the results indicated that the TLR9/NFκB signaling pathway was involved in gastric ca... DisGeNET Detail
Our findings demonstrate that bladder cancer cell lines express functional TLR4 and TLR9 with possib... DisGeNET Detail
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IFNAR1 is a predictor for overall survival in colorectal cancer and its mRNA expression correlated w... DisGeNET Detail
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TLR 4 T399I and TLR9 -1486 T>C showed a positive association with seizures and photosensitivity, res... DisGeNET Detail
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As detected by immunohistochemistry and western blotting, SPLUNC1 protein expression exhibited low o... DisGeNET Detail
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Our results show that rheumatoid arthritis synovial fibroblasts (RASF) express a series of TLRs, inc... DisGeNET Detail
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In the past, most studies focused on the intracellular TLRs, such as TLR3, TLR7, and TLR9, but recen... DisGeNET Detail
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Our findings demonstrate that bladder cancer cell lines express functional TLR4 and TLR9 with possib... DisGeNET Detail
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Overlapped Transcript Coordinates

Gene Transcript ID Exon Number Chromosome Start Stop Type Amino Mutation Transcript Position Links

Overlapped Transcript

Gene Transcript ID Chromosome Start Stop Links
Gene
-
dbSNP
rs386502799 dbSNP
Genome
hg19
Position
chr3:52,255,096-52,259,661
Variant Type
snv
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